Correction to: Early Second Trimester Maternal Serum SteroidRelated Biomarkers Associated with Autism Spectrum Disorder / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4584 Titre : Correction to: Early Second Trimester Maternal Serum SteroidRelated Biomarkers Associated with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Deborah A. BILDER, Auteur ; M. Sean ESPLIN, Auteur ; Hilary COON, Auteur ; Paul BURGHARDT, Auteur ; Erin A.S. CLARK, Auteur ; Alison FRASER, Auteur ; Ken R. SMITH, Auteur ; Whitney WORSHAM, Auteur ; Katlin CHAPPELLE, Auteur ; Thomas RAYNER, Auteur ; Amanda V. BAKIAN, Auteur Article en page(s) : p.4584 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The original version of the article has been published without funding source information. En ligne : http://dx.doi.org/10.1007/s10803-019-04206-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408 [article] Correction to: Early Second Trimester Maternal Serum SteroidRelated Biomarkers Associated with Autism Spectrum Disorder [texte imprimé] / Deborah A. BILDER, Auteur ; M. Sean ESPLIN, Auteur ; Hilary COON, Auteur ; Paul BURGHARDT, Auteur ; Erin A.S. CLARK, Auteur ; Alison FRASER, Auteur ; Ken R. SMITH, Auteur ; Whitney WORSHAM, Auteur ; Katlin CHAPPELLE, Auteur ; Thomas RAYNER, Auteur ; Amanda V. BAKIAN, Auteur . - p.4584. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4584 Index. décimale : PER Périodiques Résumé : The original version of the article has been published without funding source information. En ligne : http://dx.doi.org/10.1007/s10803-019-04206-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408

Early Second Trimester Maternal Serum Steroid-Related Biomarkers Associated with Autism Spectrum Disorder / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4572-4583 Titre : Early Second Trimester Maternal Serum Steroid-Related Biomarkers Associated with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Deborah A. BILDER, Auteur ; M. Sean ESPLIN, Auteur ; Hilary COON, Auteur ; Paul BURGHARDT, Auteur ; Erin A.S. CLARK, Auteur ; Alison FRASER, Auteur ; Ken R. SMITH, Auteur ; Whitney WORSHAM, Auteur ; Katlin CHAPPELLE, Auteur ; Thomas RAYNER, Auteur ; Amanda V. BAKIAN, Auteur Article en page(s) : p.4572-4583 Langues : Anglais (eng) Mots-clés : Autism  Biomarkers  Metabolic syndrome  Prenatal risk factors Index. décimale : PER Périodiques Résumé : Epidemiologic studies link increased autism spectrum disorder (ASD) risk to obstetrical conditions associated with inflammation and steroid dysregulation, referred to as prenatal metabolic syndrome (PNMS). This pilot study measured steroid-related biomarkers in early second trimester maternal serum collected during the first and second trimester evaluation of risk study. ASD case and PNMS exposure status of index offspring were determined through linkage with autism registries and birth certificate records. ASD case (N = 53) and control (N = 19) groups were enriched for PNMS exposure. Higher estradiol and lower sex hormone binding globulin (SHBG) were significantly associated with increased ASD risk. Study findings provide preliminary evidence to link greater placental estradiol activity with ASD and support future investigations of the prenatal steroid environment in ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04162-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408 [article] Early Second Trimester Maternal Serum Steroid-Related Biomarkers Associated with Autism Spectrum Disorder [texte imprimé] / Deborah A. BILDER, Auteur ; M. Sean ESPLIN, Auteur ; Hilary COON, Auteur ; Paul BURGHARDT, Auteur ; Erin A.S. CLARK, Auteur ; Alison FRASER, Auteur ; Ken R. SMITH, Auteur ; Whitney WORSHAM, Auteur ; Katlin CHAPPELLE, Auteur ; Thomas RAYNER, Auteur ; Amanda V. BAKIAN, Auteur . - p.4572-4583. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-11 (November 2019) . - p.4572-4583 Mots-clés : Autism  Biomarkers  Metabolic syndrome  Prenatal risk factors Index. décimale : PER Périodiques Résumé : Epidemiologic studies link increased autism spectrum disorder (ASD) risk to obstetrical conditions associated with inflammation and steroid dysregulation, referred to as prenatal metabolic syndrome (PNMS). This pilot study measured steroid-related biomarkers in early second trimester maternal serum collected during the first and second trimester evaluation of risk study. ASD case and PNMS exposure status of index offspring were determined through linkage with autism registries and birth certificate records. ASD case (N = 53) and control (N = 19) groups were enriched for PNMS exposure. Higher estradiol and lower sex hormone binding globulin (SHBG) were significantly associated with increased ASD risk. Study findings provide preliminary evidence to link greater placental estradiol activity with ASD and support future investigations of the prenatal steroid environment in ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04162-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408

Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 43-5 (May 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1196-1204 Titre : Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study Type de document : texte imprimé Auteurs : Deborah A. BILDER, Auteur ; Elizabeth L. BOTTS, Auteur ; Ken R. SMITH, Auteur ; Richard PIMENTEL, Auteur ; Megan A. FARLEY, Auteur ; Joseph VISKOCHIL, Auteur ; William M. MCMAHON, Auteur ; Heidi BLOCK, Auteur ; Edward R. RITVO, Auteur ; Ariella R. RITVO, Auteur ; Hilary H. COON, Auteur Article en page(s) : p.1196-1204 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Mortality  Causes of death  Epilepsy  Intellectual disability Index. décimale : PER Périodiques Résumé : This study’s purpose was to investigate mortality among individuals with autism spectrum disorders (ASD) ascertained during a 1980s statewide autism prevalence study (n = 305) in relation to controls. Twenty-nine of these individuals (9.5 %) died by the time of follow up, representing a hazard rate ratio of 9.9 (95 % CI 5.7–17.2) in relation to population controls. Death certificates identified respiratory, cardiac, and epileptic events as the most common causes of death. The elevated mortality risk associated with ASD in the study cohort appeared related to the presence of comorbid medical conditions and intellectual disability rather than ASD itself suggesting the importance of coordinated medical care for this high risk sub-population of individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1664-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195 [article] Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study [texte imprimé] / Deborah A. BILDER, Auteur ; Elizabeth L. BOTTS, Auteur ; Ken R. SMITH, Auteur ; Richard PIMENTEL, Auteur ; Megan A. FARLEY, Auteur ; Joseph VISKOCHIL, Auteur ; William M. MCMAHON, Auteur ; Heidi BLOCK, Auteur ; Edward R. RITVO, Auteur ; Ariella R. RITVO, Auteur ; Hilary H. COON, Auteur . - p.1196-1204. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1196-1204 Mots-clés : Autism spectrum disorders  Mortality  Causes of death  Epilepsy  Intellectual disability Index. décimale : PER Périodiques Résumé : This study’s purpose was to investigate mortality among individuals with autism spectrum disorders (ASD) ascertained during a 1980s statewide autism prevalence study (n = 305) in relation to controls. Twenty-nine of these individuals (9.5 %) died by the time of follow up, representing a hazard rate ratio of 9.9 (95 % CI 5.7–17.2) in relation to population controls. Death certificates identified respiratory, cardiac, and epileptic events as the most common causes of death. The elevated mortality risk associated with ASD in the study cohort appeared related to the presence of comorbid medical conditions and intellectual disability rather than ASD itself suggesting the importance of coordinated medical care for this high risk sub-population of individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1664-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195

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