Are Autistic Traits Measured Equivalently in Individuals With and Without An Autism Spectrum Disorder? An Invariance Analysis of the Autism Spectrum Quotient Short Form / Aja L. MURRAY in Journal of Autism and Developmental Disorders, 44-1 (January 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-1 (January 2014) . - p.55-64 Titre : Are Autistic Traits Measured Equivalently in Individuals With and Without An Autism Spectrum Disorder? An Invariance Analysis of the Autism Spectrum Quotient Short Form Type de document : Texte imprimé et/ou numérique Auteurs : Aja L. MURRAY, Auteur ; Tom BOOTH, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur Article en page(s) : p.55-64 Langues : Anglais (eng) Mots-clés : Autism  Autistic traits  Measurement invariance  Confirmatory factor analysis  Autism spectrum quotient Index. décimale : PER Périodiques Résumé : It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Form (AQ-S: Hoekstra et al. in J Autism Dev Disord 41(5):589–596, 2011) across those with (n = 148) and without (n = 168) ASD. Metric variance (equality of factor loadings), but not scalar invariance (equality of thresholds), held suggesting that the AQ-S measures the same latent traits in both groups, but with a bias in the manner in which trait levels are estimated. We, therefore, argue that the AQ-S can be used to investigate possible causes and consequences of autistic traits in both groups separately, but caution is due when combining or comparing levels of autistic traits across the two groups. En ligne : http://dx.doi.org/10.1007/s10803-013-1851-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220 [article] Are Autistic Traits Measured Equivalently in Individuals With and Without An Autism Spectrum Disorder? An Invariance Analysis of the Autism Spectrum Quotient Short Form [Texte imprimé et/ou numérique] / Aja L. MURRAY, Auteur ; Tom BOOTH, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur . - p.55-64. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-1 (January 2014) . - p.55-64 Mots-clés : Autism  Autistic traits  Measurement invariance  Confirmatory factor analysis  Autism spectrum quotient Index. décimale : PER Périodiques Résumé : It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Form (AQ-S: Hoekstra et al. in J Autism Dev Disord 41(5):589–596, 2011) across those with (n = 148) and without (n = 168) ASD. Metric variance (equality of factor loadings), but not scalar invariance (equality of thresholds), held suggesting that the AQ-S measures the same latent traits in both groups, but with a bias in the manner in which trait levels are estimated. We, therefore, argue that the AQ-S can be used to investigate possible causes and consequences of autistic traits in both groups separately, but caution is due when combining or comparing levels of autistic traits across the two groups. En ligne : http://dx.doi.org/10.1007/s10803-013-1851-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220

Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder / Aja Louise MURRAY in Journal of Autism and Developmental Disorders, 44-11 (November 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2921-2930 Titre : Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur Article en page(s) : p.2921-2930 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Range restriction  Fractionable triad  Simultaneous selection  Sampling Index. décimale : PER Périodiques Résumé : The magnitude of symptom inter-correlations in diagnosed individuals has contributed to the evidence that autism spectrum disorders (ASD) is a fractionable disorder. Such correlations may substantially under-estimate the population correlations among symptoms due to simultaneous selection on the areas of deficit required for diagnosis. Using statistical simulations of this selection mechanism, we provide estimates of the extent of this bias, given different levels of population correlation between symptoms. We then use real data to compare domain inter-correlations in the Autism Spectrum Quotient, in those with ASD versus a combined ASD and non-ASD sample. Results from both studies indicate that samples restricted to individuals with a diagnosis of ASD potentially substantially under-estimate the magnitude of association between features of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2154-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur . - p.2921-2930. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2921-2930 Mots-clés : Autism spectrum disorder  Range restriction  Fractionable triad  Simultaneous selection  Sampling Index. décimale : PER Périodiques Résumé : The magnitude of symptom inter-correlations in diagnosed individuals has contributed to the evidence that autism spectrum disorders (ASD) is a fractionable disorder. Such correlations may substantially under-estimate the population correlations among symptoms due to simultaneous selection on the areas of deficit required for diagnosis. Using statistical simulations of this selection mechanism, we provide estimates of the extent of this bias, given different levels of population correlation between symptoms. We then use real data to compare domain inter-correlations in the Autism Spectrum Quotient, in those with ASD versus a combined ASD and non-ASD sample. Results from both studies indicate that samples restricted to individuals with a diagnosis of ASD potentially substantially under-estimate the magnitude of association between features of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2154-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults / Tom BOOTH in Journal of Autism and Developmental Disorders, 43-12 (December 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2997-3000 Titre : Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults Type de document : Texte imprimé et/ou numérique Auteurs : Tom BOOTH, Auteur ; Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur ; Hollie G. BURNETT, Auteur Article en page(s) : p.2997-3000 Langues : Anglais (eng) Mots-clés : Autism  AQ  ASD  Screening  ROC analysis Index. décimale : PER Périodiques Résumé : There is a need for brief screening instruments for autistic spectrum disorders (ASD) that can be used by frontline healthcare professionals to aid in the decision as to whether an individual should be referred for a full diagnostic assessment. In this study we evaluated the ability of a short form of the autism spectrum quotient (AQ) questionnaire, the 10 item AQ-10, to correctly classify individuals as having or not having ASD. In a sample of 149 individuals with ASD and 134 controls without an ASD diagnosis, we found that the full AQ (AQ-50) abridged AQ (AQ-S) and AQ-10 all performed well as a screen for ASD. ROC analysis indicated that sensitivity, specificity and area under the curve were very similar at suggested cut-off’s for ASD across measures, with little difference in performance between the AQ-10 and full AQ-50. Results indicate the potential usefulness of the AQ-10 as a brief screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1844-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218 [article] Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults [Texte imprimé et/ou numérique] / Tom BOOTH, Auteur ; Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur ; Hollie G. BURNETT, Auteur . - p.2997-3000. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2997-3000 Mots-clés : Autism  AQ  ASD  Screening  ROC analysis Index. décimale : PER Périodiques Résumé : There is a need for brief screening instruments for autistic spectrum disorders (ASD) that can be used by frontline healthcare professionals to aid in the decision as to whether an individual should be referred for a full diagnostic assessment. In this study we evaluated the ability of a short form of the autism spectrum quotient (AQ) questionnaire, the 10 item AQ-10, to correctly classify individuals as having or not having ASD. In a sample of 149 individuals with ASD and 134 controls without an ASD diagnosis, we found that the full AQ (AQ-50) abridged AQ (AQ-S) and AQ-10 all performed well as a screen for ASD. ROC analysis indicated that sensitivity, specificity and area under the curve were very similar at suggested cut-off’s for ASD across measures, with little difference in performance between the AQ-10 and full AQ-50. Results indicate the potential usefulness of the AQ-10 as a brief screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1844-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218

Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder / Marion RUTHERFORD in Autism, 20-5 (July 2016)  

Public ISBD [article]  inAutism > 20-5 (July 2016) . - p.628-634 Titre : Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; Tess JOHNSON, Auteur ; Ciara CATCHPOLE, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Deborah MCCARTNEY, Auteur ; Aja MURRAY, Auteur Article en page(s) : p.628-634 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  diagnosis  females  gender  males Index. décimale : PER Périodiques Résumé : This article reports on gender ratio, age of diagnosis and the duration of assessment procedures in autism spectrum disorder diagnosis in a national study which included all types of clinical services for children and adults. Findings are reported from a retrospective case note analysis undertaken with a representative sample of 150 Scottish children and adults recently diagnosed with autism spectrum disorder. The study reports key findings that the gender ratio in this consecutively referred cohort is lower than anticipated in some age groups and reduces with increasing age. The gender ratio in children, together with the significant difference in the mean age of referral and diagnosis for girls compared to boys, adds evidence of delayed recognition of autism spectrum disorder in younger girls. There was no significant difference in duration of assessment for males and females suggesting that delays in diagnosis of females occur prior to referral for assessment. Implications for practice and research are considered. En ligne : http://dx.doi.org/10.1177/1362361315617879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 [article] Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; Tess JOHNSON, Auteur ; Ciara CATCHPOLE, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Deborah MCCARTNEY, Auteur ; Aja MURRAY, Auteur . - p.628-634. Langues : Anglais (eng) in Autism > 20-5 (July 2016) . - p.628-634 Mots-clés : autism spectrum disorder  diagnosis  females  gender  males Index. décimale : PER Périodiques Résumé : This article reports on gender ratio, age of diagnosis and the duration of assessment procedures in autism spectrum disorder diagnosis in a national study which included all types of clinical services for children and adults. Findings are reported from a retrospective case note analysis undertaken with a representative sample of 150 Scottish children and adults recently diagnosed with autism spectrum disorder. The study reports key findings that the gender ratio in this consecutively referred cohort is lower than anticipated in some age groups and reduces with increasing age. The gender ratio in children, together with the significant difference in the mean age of referral and diagnosis for girls compared to boys, adds evidence of delayed recognition of autism spectrum disorder in younger girls. There was no significant difference in duration of assessment for males and females suggesting that delays in diagnosis of females occur prior to referral for assessment. Implications for practice and research are considered. En ligne : http://dx.doi.org/10.1177/1362361315617879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290

A national study to investigate the clinical use of standardised instruments in autism spectrum disorder assessment of children and adults in Scotland / Marion RUTHERFORD in Research in Autism Spectrum Disorders, 29-30 (September–October 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 29-30 (September–October 2016) . - p.93-100 Titre : A national study to investigate the clinical use of standardised instruments in autism spectrum disorder assessment of children and adults in Scotland Type de document : Texte imprimé et/ou numérique Auteurs : Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Anne O’HARE, Auteur ; Deborah MCCARTNEY, Auteur ; Ian FINLAYSON, Auteur Article en page(s) : p.93-100 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Children  Adults  Assessment Index. décimale : PER Périodiques Résumé : AbstractBackground There are few large scale studies about the nature and extent of the actual use of standardised assessments for Autism Spectrum Disorder diagnosis in clinical practice. This study compares and contrasts practice in diagnostic services for both adults and children. Method We conducted an analysis of retrospective case notes from 150 cases (70 adult, 80 children) assessed for Autism Spectrum Disorder by 16 diagnostic services. Results We found differences between adult and child services in staff training and use of standardised assessment during diagnosis. All child services had staff trained in and regularly using standardised assessments. Most adult services had staff trained in using instruments but only half used them regularly. Administration of standardised ASD assessments was ten times more likely in children than in adults (OR = 10.1; CI = 4.24, 24.0). Child services selected the ADOS as the standardised tool and adult services selected the DISCO, with very little overlap. Decisions to administer standardised tools were not based on case complexity but rather the same process was applied to all referrals within a service. The three recommended components of assessment (clinical history, clinical observation and contextual information) were included for the majority of cases, although clinical observation was more frequently used with children than with adults. Conclusions Based on the findings, we suggest a need for a wider range of appropriate assessments for use with adults, particularly those with an intellectual disability and for further research into the reasons behind the choices clinicians make during the assessment process. For child services in Scotland, there is a need for more training in use of current diagnostic interviews. Clinicians did not vary tools used based on complexity, suggesting that this is a notion still to be clearly defined and operationalised in clinical decision making about the use of standardised assessments. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.05.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 [article] A national study to investigate the clinical use of standardised instruments in autism spectrum disorder assessment of children and adults in Scotland [Texte imprimé et/ou numérique] / Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Anne O’HARE, Auteur ; Deborah MCCARTNEY, Auteur ; Ian FINLAYSON, Auteur . - p.93-100. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 29-30 (September–October 2016) . - p.93-100 Mots-clés : Autism Spectrum Disorder  Children  Adults  Assessment Index. décimale : PER Périodiques Résumé : AbstractBackground There are few large scale studies about the nature and extent of the actual use of standardised assessments for Autism Spectrum Disorder diagnosis in clinical practice. This study compares and contrasts practice in diagnostic services for both adults and children. Method We conducted an analysis of retrospective case notes from 150 cases (70 adult, 80 children) assessed for Autism Spectrum Disorder by 16 diagnostic services. Results We found differences between adult and child services in staff training and use of standardised assessment during diagnosis. All child services had staff trained in and regularly using standardised assessments. Most adult services had staff trained in using instruments but only half used them regularly. Administration of standardised ASD assessments was ten times more likely in children than in adults (OR = 10.1; CI = 4.24, 24.0). Child services selected the ADOS as the standardised tool and adult services selected the DISCO, with very little overlap. Decisions to administer standardised tools were not based on case complexity but rather the same process was applied to all referrals within a service. The three recommended components of assessment (clinical history, clinical observation and contextual information) were included for the majority of cases, although clinical observation was more frequently used with children than with adults. Conclusions Based on the findings, we suggest a need for a wider range of appropriate assessments for use with adults, particularly those with an intellectual disability and for further research into the reasons behind the choices clinicians make during the assessment process. For child services in Scotland, there is a need for more training in use of current diagnostic interviews. Clinicians did not vary tools used based on complexity, suggesting that this is a notion still to be clearly defined and operationalised in clinical decision making about the use of standardised assessments. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.05.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292

Screening for intellectual disability in autistic people: A brief report / Karen MCKENZIE in Research in Autism Spectrum Disorders, 100 (February 2023)  

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Screening tools for autism spectrum disorder, used with people with an intellectual disability: A systematic review / Dale METCALFE in Research in Autism Spectrum Disorders, 74 (June 2020)  

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Sleep Disorders / Karen MCKENZIE  

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Structural validation of the abridged Autism Spectrum Quotient–Short Form in a clinical sample of people with autism spectrum disorders / Renate KUENSSBERG in Autism, 18-2 (February 2014)  

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The relation between practice that is consistent with NICE guideline 142 recommendations and waiting times within Autism Spectrum Disorder diagnostic services / Karen MCKENZIE in Research in Autism Spectrum Disorders, 26 (June 2016)  

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The relationship between waiting times and ‘adherence’ to the Scottish Intercollegiate Guidelines Network 98 guideline in autism spectrum disorder diagnostic services in Scotland / Karen MCKENZIE in Autism, 20-4 (May 2016)  

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Why are they waiting? Exploring professional perspectives and developing solutions to delayed diagnosis of autism spectrum disorder in adults and children / Marion RUTHERFORD in Research in Autism Spectrum Disorders, 31 (November 2016)  

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