Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder / Aja Louise MURRAY in Journal of Autism and Developmental Disorders, 44-11 (November 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2921-2930 Titre : Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur Article en page(s) : p.2921-2930 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Range restriction  Fractionable triad  Simultaneous selection  Sampling Index. décimale : PER Périodiques Résumé : The magnitude of symptom inter-correlations in diagnosed individuals has contributed to the evidence that autism spectrum disorders (ASD) is a fractionable disorder. Such correlations may substantially under-estimate the population correlations among symptoms due to simultaneous selection on the areas of deficit required for diagnosis. Using statistical simulations of this selection mechanism, we provide estimates of the extent of this bias, given different levels of population correlation between symptoms. We then use real data to compare domain inter-correlations in the Autism Spectrum Quotient, in those with ASD versus a combined ASD and non-ASD sample. Results from both studies indicate that samples restricted to individuals with a diagnosis of ASD potentially substantially under-estimate the magnitude of association between features of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2154-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Are We Under-Estimating the Association Between Autism Symptoms?: The Importance of Considering Simultaneous Selection When Using Samples of Individuals Who Meet Diagnostic Criteria for an Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur . - p.2921-2930. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2921-2930 Mots-clés : Autism spectrum disorder  Range restriction  Fractionable triad  Simultaneous selection  Sampling Index. décimale : PER Périodiques Résumé : The magnitude of symptom inter-correlations in diagnosed individuals has contributed to the evidence that autism spectrum disorders (ASD) is a fractionable disorder. Such correlations may substantially under-estimate the population correlations among symptoms due to simultaneous selection on the areas of deficit required for diagnosis. Using statistical simulations of this selection mechanism, we provide estimates of the extent of this bias, given different levels of population correlation between symptoms. We then use real data to compare domain inter-correlations in the Autism Spectrum Quotient, in those with ASD versus a combined ASD and non-ASD sample. Results from both studies indicate that samples restricted to individuals with a diagnosis of ASD potentially substantially under-estimate the magnitude of association between features of ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2154-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults / Tom BOOTH in Journal of Autism and Developmental Disorders, 43-12 (December 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2997-3000 Titre : Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults Type de document : Texte imprimé et/ou numérique Auteurs : Tom BOOTH, Auteur ; Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur ; Hollie G. BURNETT, Auteur Article en page(s) : p.2997-3000 Langues : Anglais (eng) Mots-clés : Autism  AQ  ASD  Screening  ROC analysis Index. décimale : PER Périodiques Résumé : There is a need for brief screening instruments for autistic spectrum disorders (ASD) that can be used by frontline healthcare professionals to aid in the decision as to whether an individual should be referred for a full diagnostic assessment. In this study we evaluated the ability of a short form of the autism spectrum quotient (AQ) questionnaire, the 10 item AQ-10, to correctly classify individuals as having or not having ASD. In a sample of 149 individuals with ASD and 134 controls without an ASD diagnosis, we found that the full AQ (AQ-50) abridged AQ (AQ-S) and AQ-10 all performed well as a screen for ASD. ROC analysis indicated that sensitivity, specificity and area under the curve were very similar at suggested cut-off’s for ASD across measures, with little difference in performance between the AQ-10 and full AQ-50. Results indicate the potential usefulness of the AQ-10 as a brief screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1844-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218 [article] Brief Report: An Evaluation of the AQ-10 as a Brief Screening Instrument for ASD in Adults [Texte imprimé et/ou numérique] / Tom BOOTH, Auteur ; Aja Louise MURRAY, Auteur ; Karen MCKENZIE, Auteur ; Renate KUENSSBERG, Auteur ; Michael O’DONNELL, Auteur ; Hollie G. BURNETT, Auteur . - p.2997-3000. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2997-3000 Mots-clés : Autism  AQ  ASD  Screening  ROC analysis Index. décimale : PER Périodiques Résumé : There is a need for brief screening instruments for autistic spectrum disorders (ASD) that can be used by frontline healthcare professionals to aid in the decision as to whether an individual should be referred for a full diagnostic assessment. In this study we evaluated the ability of a short form of the autism spectrum quotient (AQ) questionnaire, the 10 item AQ-10, to correctly classify individuals as having or not having ASD. In a sample of 149 individuals with ASD and 134 controls without an ASD diagnosis, we found that the full AQ (AQ-50) abridged AQ (AQ-S) and AQ-10 all performed well as a screen for ASD. ROC analysis indicated that sensitivity, specificity and area under the curve were very similar at suggested cut-off’s for ASD across measures, with little difference in performance between the AQ-10 and full AQ-50. Results indicate the potential usefulness of the AQ-10 as a brief screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1844-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218

Developmental associations between bullying victimization and suicidal ideation and direct self-injurious behavior in adolescence and emerging adulthood / Xinxin ZHU in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.820-828 Titre : Developmental associations between bullying victimization and suicidal ideation and direct self-injurious behavior in adolescence and emerging adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Xinxin ZHU, Auteur ; Helen GRIFFITHS, Auteur ; Manuel EISNER, Auteur ; Urs HEPP, Auteur ; Denis RIBEAUD, Auteur ; Aja Louise MURRAY, Auteur Article en page(s) : p.820-828 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Bullying  Child  Crime Victims  Humans  Self-Injurious Behavior/epidemiology  Suicidal Ideation  Suicide  Young Adult  adolescence and emerging adulthood  direct self-injurious behavior  general and sexual bullying victimization Index. décimale : PER Périodiques Résumé : BACKGROUND: Bullying, suicide, and self-injury are significant issues among young people. Extensive research has documented bullying victimization associations with suicidal ideation and self-injury; however, the modeling approaches used have mostly not addressed the relations between these constructs at the within-person level, and it is these links that are critical for testing developmental theories and guiding intervention efforts. This examined the within-person, bidirectional relations between these constructs in adolescence and emerging adulthood. METHODS: Participants were from the Zurich Project on Social Development from Childhood to Adulthood (z-proso). Random intercept cross-lagged panel models (RI-CLPMs) were fit to general and sexual bullying victimization and suicidal ideation data at ages 15, 17, and 20 (n=1465), and general and sexual victimization and direct self-injurious behavior data at ages 13, 15, 17, and 20 (n=1482). RESULTS: There was a positive within-person effect of age 15 general bullying victimization on age 17 suicidal ideation (?=.10) and age 17 suicidal ideation on age 20 general bullying victimization (?=.14). CONCLUSIONS: General bullying victimization and suicidal ideation may have detrimental effects on each other over development but at different stages. En ligne : http://dx.doi.org/10.1111/jcpp.13529 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] Developmental associations between bullying victimization and suicidal ideation and direct self-injurious behavior in adolescence and emerging adulthood [Texte imprimé et/ou numérique] / Xinxin ZHU, Auteur ; Helen GRIFFITHS, Auteur ; Manuel EISNER, Auteur ; Urs HEPP, Auteur ; Denis RIBEAUD, Auteur ; Aja Louise MURRAY, Auteur . - p.820-828. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.820-828 Mots-clés : Adolescent  Adult  Bullying  Child  Crime Victims  Humans  Self-Injurious Behavior/epidemiology  Suicidal Ideation  Suicide  Young Adult  adolescence and emerging adulthood  direct self-injurious behavior  general and sexual bullying victimization Index. décimale : PER Périodiques Résumé : BACKGROUND: Bullying, suicide, and self-injury are significant issues among young people. Extensive research has documented bullying victimization associations with suicidal ideation and self-injury; however, the modeling approaches used have mostly not addressed the relations between these constructs at the within-person level, and it is these links that are critical for testing developmental theories and guiding intervention efforts. This examined the within-person, bidirectional relations between these constructs in adolescence and emerging adulthood. METHODS: Participants were from the Zurich Project on Social Development from Childhood to Adulthood (z-proso). Random intercept cross-lagged panel models (RI-CLPMs) were fit to general and sexual bullying victimization and suicidal ideation data at ages 15, 17, and 20 (n=1465), and general and sexual victimization and direct self-injurious behavior data at ages 13, 15, 17, and 20 (n=1482). RESULTS: There was a positive within-person effect of age 15 general bullying victimization on age 17 suicidal ideation (?=.10) and age 17 suicidal ideation on age 20 general bullying victimization (?=.14). CONCLUSIONS: General bullying victimization and suicidal ideation may have detrimental effects on each other over development but at different stages. En ligne : http://dx.doi.org/10.1111/jcpp.13529 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

Does emotion dysregulation mediate the association between ADHD symptoms and internalizing problems? A longitudinal within-person analysis in a large population-representative study / Evelyn Mary-Ann ANTONY in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1583-1590 Titre : Does emotion dysregulation mediate the association between ADHD symptoms and internalizing problems? A longitudinal within-person analysis in a large population-representative study Type de document : Texte imprimé et/ou numérique Auteurs : Evelyn Mary-Ann ANTONY, Auteur ; Milla PIHLAJAMAKI, Auteur ; Lydia Gabriela SPEYER, Auteur ; Aja Louise MURRAY, Auteur Article en page(s) : p.1583-1590 Langues : Anglais (eng) Mots-clés : Child  Male  Humans  Attention Deficit Disorder with Hyperactivity/complications  Cohort Studies  Anxiety/epidemiology  Anxiety Disorders  Interpersonal Relations  Attention-deficit/hyperactivity disorder  autoregressive latent trajectory model with structured residuals  child development  emotion dysregulation  internalizing problems Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research has suggested that children with attention-deficit/hyperactivity disorder (ADHD) symptoms commonly show emotion dysregulation difficulties. These difficulties may partly explain the strong tendency for internalizing problems such as anxiety and depression to co-occur with ADHD symptoms. However, no study has yet provided a longitudinal analysis of the within-person links between ADHD symptoms, emotion dysregulation, and internalizing problems necessary to examine this hypothesis from a developmental perspective. METHODS: We used data from the age 3, 5, and 7 waves of the large UK population-representative Millennium Cohort Study (n=9,619, 4,885 males) and fit gender-stratified autoregressive latent trajectory models with structured residuals (ALT-SR) to disaggregate within- and between-person relations between ADHD symptom, emotion dysregulation, and internalizing problem symptoms. RESULTS: We found that emotion dysregulation significantly mediated the longitudinal within-person association between ADHD symptoms and internalizing problems. CONCLUSIONS: Results underline the promise of targeting emotion dysregulation as a means of preventing internalizing problems co-occurring with ADHD symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.13624 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Does emotion dysregulation mediate the association between ADHD symptoms and internalizing problems? A longitudinal within-person analysis in a large population-representative study [Texte imprimé et/ou numérique] / Evelyn Mary-Ann ANTONY, Auteur ; Milla PIHLAJAMAKI, Auteur ; Lydia Gabriela SPEYER, Auteur ; Aja Louise MURRAY, Auteur . - p.1583-1590. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1583-1590 Mots-clés : Child  Male  Humans  Attention Deficit Disorder with Hyperactivity/complications  Cohort Studies  Anxiety/epidemiology  Anxiety Disorders  Interpersonal Relations  Attention-deficit/hyperactivity disorder  autoregressive latent trajectory model with structured residuals  child development  emotion dysregulation  internalizing problems Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research has suggested that children with attention-deficit/hyperactivity disorder (ADHD) symptoms commonly show emotion dysregulation difficulties. These difficulties may partly explain the strong tendency for internalizing problems such as anxiety and depression to co-occur with ADHD symptoms. However, no study has yet provided a longitudinal analysis of the within-person links between ADHD symptoms, emotion dysregulation, and internalizing problems necessary to examine this hypothesis from a developmental perspective. METHODS: We used data from the age 3, 5, and 7 waves of the large UK population-representative Millennium Cohort Study (n=9,619, 4,885 males) and fit gender-stratified autoregressive latent trajectory models with structured residuals (ALT-SR) to disaggregate within- and between-person relations between ADHD symptom, emotion dysregulation, and internalizing problem symptoms. RESULTS: We found that emotion dysregulation significantly mediated the longitudinal within-person association between ADHD symptoms and internalizing problems. CONCLUSIONS: Results underline the promise of targeting emotion dysregulation as a means of preventing internalizing problems co-occurring with ADHD symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.13624 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Investigating diagnostic bias in autism spectrum conditions: An item response theory analysis of sex bias in the AQ-10 / Aja Louise MURRAY in Autism Research, 10-5 (May 2017)  

Public ISBD [article]  inAutism Research > 10-5 (May 2017) . - p.790-800 Titre : Investigating diagnostic bias in autism spectrum conditions: An item response theory analysis of sex bias in the AQ-10 Type de document : Texte imprimé et/ou numérique Auteurs : Aja Louise MURRAY, Auteur ; Carrie ALLISON, Auteur ; Paula L. SMITH, Auteur ; Simon BARON-COHEN, Auteur ; Tom BOOTH, Auteur ; Bonnie AUYEUNG, Auteur Article en page(s) : p.790-800 Langues : Anglais (eng) Mots-clés : sex differences  autism  screening  autism spectrum quotient  AQ-10  item response theory  differential item functioning  differential test functioning Index. décimale : PER Périodiques Résumé : Diagnostic bias is a concern in autism spectrum conditions (ASC) where prevalence and presentation differ by sex. To ensure that females with ASC are not under-identified, it is important that ASC screening tools do not systematically underestimate autistic traits in females relative to males. We evaluated whether the AQ-10, a brief screen for ASC recommended by the National Institute of Clinical Excellence in cases of suspected ASC, exhibits such a bias. Using an item response theory approach, we evaluated differential item functioning and differential test functioning. We found that although individual items showed some sex bias, these biases at times favored males and at other times favored females. Thus, at the level of test scores the item-level biases cancelled out to give an unbiased overall score. Results support the continued use of the AQ-10 sum score in its current form; however, suggest that caution should be exercised when interpreting responses to individual items. The nature of the item level biases could serve as a guide for future research into how ASC affects males and females differently. En ligne : http://dx.doi.org/10.1002/aur.1724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] Investigating diagnostic bias in autism spectrum conditions: An item response theory analysis of sex bias in the AQ-10 [Texte imprimé et/ou numérique] / Aja Louise MURRAY, Auteur ; Carrie ALLISON, Auteur ; Paula L. SMITH, Auteur ; Simon BARON-COHEN, Auteur ; Tom BOOTH, Auteur ; Bonnie AUYEUNG, Auteur . - p.790-800. Langues : Anglais (eng) in Autism Research > 10-5 (May 2017) . - p.790-800 Mots-clés : sex differences  autism  screening  autism spectrum quotient  AQ-10  item response theory  differential item functioning  differential test functioning Index. décimale : PER Périodiques Résumé : Diagnostic bias is a concern in autism spectrum conditions (ASC) where prevalence and presentation differ by sex. To ensure that females with ASC are not under-identified, it is important that ASC screening tools do not systematically underestimate autistic traits in females relative to males. We evaluated whether the AQ-10, a brief screen for ASC recommended by the National Institute of Clinical Excellence in cases of suspected ASC, exhibits such a bias. Using an item response theory approach, we evaluated differential item functioning and differential test functioning. We found that although individual items showed some sex bias, these biases at times favored males and at other times favored females. Thus, at the level of test scores the item-level biases cancelled out to give an unbiased overall score. Results support the continued use of the AQ-10 sum score in its current form; however, suggest that caution should be exercised when interpreting responses to individual items. The nature of the item level biases could serve as a guide for future research into how ASC affects males and females differently. En ligne : http://dx.doi.org/10.1002/aur.1724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

Investigating the Mediating Role of Executive Function in the Relationship Between ADHD and DCD Symptoms and Depression in Adults / Maria C. BROLETTI in Journal of Autism and Developmental Disorders, 54-12 (December 2024)  

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Polygenic risks for joint developmental trajectories of internalizing and externalizing problems: findings from the ALSPAC cohort / Lydia Gabriela SPEYER in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

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A symptom level perspective on reactive and proactive aggressive behaviours and ADHD symptoms in childhood / Lydia Gabriela SPEYER in Journal of Child Psychology and Psychiatry, 63-9 (September 2022)  

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The role of moment-to-moment dynamics of perceived stress and negative affect in co-occurring ADHD and internalising symptoms / Lydia Gabriela SPEYER in Journal of Autism and Developmental Disorders, 53-3 (March 2023)  

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Within-family relations of mental health problems across childhood and adolescence / Lydia Gabriela SPEYER in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

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Within-person analysis of developmental cascades between externalising and internalising problems / Aja Louise MURRAY in Journal of Child Psychology and Psychiatry, 61-6 (June 2020)  

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