Annual Research Review: Exposure to environmental chemicals and psychosocial stress and the development of children's learning difficulties / Amy E. MARGOLIS in Journal of Child Psychology and Psychiatry, 66-4 (April 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-4 (April 2025) . - p.547-568 Titre : Annual Research Review: Exposure to environmental chemicals and psychosocial stress and the development of children's learning difficulties Type de document : Texte imprimé et/ou numérique Auteurs : Amy E. MARGOLIS, Auteur ; Alex DRANOVSKY, Auteur ; David PAGLIACCIO, Auteur ; Gazi AZAD, Auteur ; Virginia RAUH, Auteur ; Julie HERBSTMAN, Auteur Article en page(s) : p.547-568 Langues : Anglais (eng) Mots-clés : Learning difficulties  environmental exposures  brain development  stress Index. décimale : PER Périodiques Résumé : Although awareness of the role of environmental exposures in children's cognitive development is increasing, learning difficulties have not yet been a major focus of environmental health science. Learning difficulties disproportionately affect children living in economic disadvantage, yielding an ?achievement gap.? Studies examining the neurobiology of reading and math have mostly included economically advantaged youth, leaving a great deal unknown about the neural underpinnings of reading and math difficulties in youth living in disadvantaged contexts. Critically, due to environmental injustice, these youth are disproportionately exposed to environmental neurotoxicants. Herein, we review literature supporting a theoretical framework of environmentally associated phenotypes of learning difficulties. We propose that prenatal exposure to neurotoxicants and early-life exposure to psychosocial stressors increases risk for learning difficulties via effects on neural circuits that support cognitive processes which, in addition to literacy and numeracy, are integral to acquiring and performing academic skills. We describe models in which (1) prenatal exposure to air pollution has a main effect on learning via brain structure and function or associated domain-general cognitive processes and (2) a joint ?two-hit? pathway in which prenatal air pollution exposure followed by early life stress?when combined and sequential?increases risk for learning difficulties also via effects on brain structure, function, and/or associated cognitive processes. We review a select literature documenting effects of exposure to pollutants and early life stress on relevant neural circuits and associated cognitive processes in animal models and parallel findings in human epidemiologic studies. We advocate for team science in which researchers, practitioners, and policymakers collaborate to increase health literacy about environmentally associated phenotypes of learning difficulties and support the development of precision-oriented instructional and environmental intervention methods for youth living in economic disadvantage. En ligne : https://doi.org/10.1111/jcpp.14137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550 [article] Annual Research Review: Exposure to environmental chemicals and psychosocial stress and the development of children's learning difficulties [Texte imprimé et/ou numérique] / Amy E. MARGOLIS, Auteur ; Alex DRANOVSKY, Auteur ; David PAGLIACCIO, Auteur ; Gazi AZAD, Auteur ; Virginia RAUH, Auteur ; Julie HERBSTMAN, Auteur . - p.547-568. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-4 (April 2025) . - p.547-568 Mots-clés : Learning difficulties  environmental exposures  brain development  stress Index. décimale : PER Périodiques Résumé : Although awareness of the role of environmental exposures in children's cognitive development is increasing, learning difficulties have not yet been a major focus of environmental health science. Learning difficulties disproportionately affect children living in economic disadvantage, yielding an ?achievement gap.? Studies examining the neurobiology of reading and math have mostly included economically advantaged youth, leaving a great deal unknown about the neural underpinnings of reading and math difficulties in youth living in disadvantaged contexts. Critically, due to environmental injustice, these youth are disproportionately exposed to environmental neurotoxicants. Herein, we review literature supporting a theoretical framework of environmentally associated phenotypes of learning difficulties. We propose that prenatal exposure to neurotoxicants and early-life exposure to psychosocial stressors increases risk for learning difficulties via effects on neural circuits that support cognitive processes which, in addition to literacy and numeracy, are integral to acquiring and performing academic skills. We describe models in which (1) prenatal exposure to air pollution has a main effect on learning via brain structure and function or associated domain-general cognitive processes and (2) a joint ?two-hit? pathway in which prenatal air pollution exposure followed by early life stress?when combined and sequential?increases risk for learning difficulties also via effects on brain structure, function, and/or associated cognitive processes. We review a select literature documenting effects of exposure to pollutants and early life stress on relevant neural circuits and associated cognitive processes in animal models and parallel findings in human epidemiologic studies. We advocate for team science in which researchers, practitioners, and policymakers collaborate to increase health literacy about environmentally associated phenotypes of learning difficulties and support the development of precision-oriented instructional and environmental intervention methods for youth living in economic disadvantage. En ligne : https://doi.org/10.1111/jcpp.14137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550

Brain–behavior relationships in the experience and regulation of negative emotion in healthy children: Implications for risk for childhood depression / David PAGLIACCIO in Development and Psychopathology, 26-4 (Part 2) (November 2014)  

Public ISBD [article]  inDevelopment and Psychopathology > 26-4 (Part 2) (November 2014) . - p.1289-1303 Titre : Brain–behavior relationships in the experience and regulation of negative emotion in healthy children: Implications for risk for childhood depression Type de document : Texte imprimé et/ou numérique Auteurs : David PAGLIACCIO, Auteur ; Joan L. LUBY, Auteur ; Katherine R. LUKING, Auteur ; Andrew C. BELDEN, Auteur ; Deanna M. BARCH, Auteur Année de publication : 2014 Article en page(s) : p.1289-1303 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Structural and functional alterations in a variety of brain regions have been associated with depression and risk for depression across the life span. A majority of these regions are associated with emotion reactivity and/or regulation. However, it is generally unclear what mechanistic role these alterations play in the etiology of depression. A first step toward understanding this is to characterize the relationships between variation in brain structure/function and individual differences in depression severity and related processes, particularly emotion regulation. To this end, the current study examines how brain structure and function predict concurrent and longitudinal measures of depression symptomology and emotion regulation skills in psychiatrically healthy school-age children (N = 60). Specifically, we found that smaller hippocampus volumes and greater responses to sad faces in emotion reactivity regions predict increased depressive symptoms at the time of scan, whereas larger amygdala volumes, smaller insula volumes, and greater responses in emotion reactivity regions predict decreased emotion regulation skills. In addition, larger insula volumes predict improvements in emotion regulation skills even after accounting for emotion regulation at the time of scan. Understanding brain–behavior relationships in psychiatrically healthy samples, especially early in development, will help inform normative developmental trajectories and neural alterations in depression and other affective pathology. En ligne : http://dx.doi.org/10.1017/S0954579414001035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245 [article] Brain–behavior relationships in the experience and regulation of negative emotion in healthy children: Implications for risk for childhood depression [Texte imprimé et/ou numérique] / David PAGLIACCIO, Auteur ; Joan L. LUBY, Auteur ; Katherine R. LUKING, Auteur ; Andrew C. BELDEN, Auteur ; Deanna M. BARCH, Auteur . - 2014 . - p.1289-1303. Langues : Anglais (eng) in Development and Psychopathology > 26-4 (Part 2) (November 2014) . - p.1289-1303 Index. décimale : PER Périodiques Résumé : Structural and functional alterations in a variety of brain regions have been associated with depression and risk for depression across the life span. A majority of these regions are associated with emotion reactivity and/or regulation. However, it is generally unclear what mechanistic role these alterations play in the etiology of depression. A first step toward understanding this is to characterize the relationships between variation in brain structure/function and individual differences in depression severity and related processes, particularly emotion regulation. To this end, the current study examines how brain structure and function predict concurrent and longitudinal measures of depression symptomology and emotion regulation skills in psychiatrically healthy school-age children (N = 60). Specifically, we found that smaller hippocampus volumes and greater responses to sad faces in emotion reactivity regions predict increased depressive symptoms at the time of scan, whereas larger amygdala volumes, smaller insula volumes, and greater responses in emotion reactivity regions predict decreased emotion regulation skills. In addition, larger insula volumes predict improvements in emotion regulation skills even after accounting for emotion regulation at the time of scan. Understanding brain–behavior relationships in psychiatrically healthy samples, especially early in development, will help inform normative developmental trajectories and neural alterations in depression and other affective pathology. En ligne : http://dx.doi.org/10.1017/S0954579414001035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245

Detecting adolescent depression through passive monitoring of linguistic markers in smartphone communication / Esha TRIVEDI ; Lilian Y. LI ; Fiona HELGREN ; Emily ZHANG ; Aishwarya SRITHARAN ; Rachel A. CHERNER ; David PAGLIACCIO ; Katherine DURHAM ; Mia KYLER ; Trinity C. TSE ; Savannah N. BUCHANAN ; Nicholas B. ALLEN ; Stewart A. SHANKMAN ; Randy P. AUERBACH in Journal of Child Psychology and Psychiatry, 65-7 (July 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-7 (July 2024) . - p.932-941 Titre : Detecting adolescent depression through passive monitoring of linguistic markers in smartphone communication Type de document : Texte imprimé et/ou numérique Auteurs : Esha TRIVEDI, Auteur ; Lilian Y. LI, Auteur ; Fiona HELGREN, Auteur ; Emily ZHANG, Auteur ; Aishwarya SRITHARAN, Auteur ; Rachel A. CHERNER, Auteur ; David PAGLIACCIO, Auteur ; Katherine DURHAM, Auteur ; Mia KYLER, Auteur ; Trinity C. TSE, Auteur ; Savannah N. BUCHANAN, Auteur ; Nicholas B. ALLEN, Auteur ; Stewart A. SHANKMAN, Auteur ; Randy P. AUERBACH, Auteur Article en page(s) : p.932-941 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Cross sectional studies have identified linguistic correlates of major depressive disorder (MDD) in smartphone communication. However, it is unclear whether monitoring these linguistic characteristics can detect when an individual is experiencing MDD, which would facilitate timely intervention. Methods Approximately 1.2 million messages typed into smartphone social communication apps (e.g. texting, social media) were passively collected from 90 adolescents with a range of depression severity over a 12-month period. Sentiment (i.e. positive vs. negative valence of text), proportions of first-person singular pronouns (e.g. 'I'), and proportions of absolutist words (e.g. 'all') were computed for each message and converted to weekly aggregates temporally aligned with weekly MDD statuses obtained from retrospective interviews. Idiographic, multilevel logistic regression models tested whether within-person deviations in these linguistic features were associated with the probability of concurrently meeting threshold for MDD. Results Using more first-person singular pronouns in smartphone communication relative to one's own average was associated with higher odds of meeting threshold for MDD in the concurrent week (OR = 1.29; p = .007). Sentiment (OR = 1.07; p = .54) and use of absolutist words (OR = 0.99; p = .90) were not related to weekly MDD. Conclusions Passively monitoring use of first-person singular pronouns in adolescents' smartphone communication may help detect MDD, providing novel opportunities for early intervention. En ligne : https://doi.org/10.1111/jcpp.13931 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=532 [article] Detecting adolescent depression through passive monitoring of linguistic markers in smartphone communication [Texte imprimé et/ou numérique] / Esha TRIVEDI, Auteur ; Lilian Y. LI, Auteur ; Fiona HELGREN, Auteur ; Emily ZHANG, Auteur ; Aishwarya SRITHARAN, Auteur ; Rachel A. CHERNER, Auteur ; David PAGLIACCIO, Auteur ; Katherine DURHAM, Auteur ; Mia KYLER, Auteur ; Trinity C. TSE, Auteur ; Savannah N. BUCHANAN, Auteur ; Nicholas B. ALLEN, Auteur ; Stewart A. SHANKMAN, Auteur ; Randy P. AUERBACH, Auteur . - p.932-941. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-7 (July 2024) . - p.932-941 Index. décimale : PER Périodiques Résumé : Background Cross sectional studies have identified linguistic correlates of major depressive disorder (MDD) in smartphone communication. However, it is unclear whether monitoring these linguistic characteristics can detect when an individual is experiencing MDD, which would facilitate timely intervention. Methods Approximately 1.2 million messages typed into smartphone social communication apps (e.g. texting, social media) were passively collected from 90 adolescents with a range of depression severity over a 12-month period. Sentiment (i.e. positive vs. negative valence of text), proportions of first-person singular pronouns (e.g. 'I'), and proportions of absolutist words (e.g. 'all') were computed for each message and converted to weekly aggregates temporally aligned with weekly MDD statuses obtained from retrospective interviews. Idiographic, multilevel logistic regression models tested whether within-person deviations in these linguistic features were associated with the probability of concurrently meeting threshold for MDD. Results Using more first-person singular pronouns in smartphone communication relative to one's own average was associated with higher odds of meeting threshold for MDD in the concurrent week (OR = 1.29; p = .007). Sentiment (OR = 1.07; p = .54) and use of absolutist words (OR = 0.99; p = .90) were not related to weekly MDD. Conclusions Passively monitoring use of first-person singular pronouns in adolescents' smartphone communication may help detect MDD, providing novel opportunities for early intervention. En ligne : https://doi.org/10.1111/jcpp.13931 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=532

Developmental pathways to social anxiety and irritability: The role of the ERN / Courtney A. FILIPPI in Development and Psychopathology, 32-3 (August 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-3 (August 2020) . - p.897-907 Titre : Developmental pathways to social anxiety and irritability: The role of the ERN Type de document : Texte imprimé et/ou numérique Auteurs : Courtney A. FILIPPI, Auteur ; Anni R. SUBAR, Auteur ; Jessica F. SACHS, Auteur ; Katharina KIRCANSKI, Auteur ; George BUZZELL, Auteur ; David PAGLIACCIO, Auteur ; Rany ABEND, Auteur ; Nathan A. FOX, Auteur ; Ellen LEIBENLUFT, Auteur ; Daniel S. PINE, Auteur Article en page(s) : p.897-907 Langues : Anglais (eng) Mots-clés : Ern  behavioral inhibition  developmental pathways  irritability  psychopathology Index. décimale : PER Périodiques Résumé : Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We tested whether error-related negativity (ERN) moderates the link between early behavior and later psychopathology in two early childhood phenotypes: behavioral inhibition and irritability. From ages 2 to 7 years, children (n = 291) were assessed longitudinally for behavioral inhibition (BI) and irritability. Behavioral inhibition was assessed via maternal report and behavioral responses to novelty. Childhood irritability was assessed using the Child Behavior Checklist. At age 12, an electroencephalogram (EEG) was recorded while children performed a flanker task to measure ERN, a neural indicator of error monitoring. Clinical assessments of anxiety and irritability were conducted using questionnaires (i.e., Screen for Child Anxiety Related Disorders and Affective Reactivity Index) and clinical interviews. Error monitoring interacted with early BI and early irritability to predict later psychopathology. Among children with high BI, an enhanced ERN predicted greater social anxiety at age 12. In contrast, children with high childhood irritability and blunted ERN predicted greater irritability at age 12. This converges with previous work and provides novel insight into the specificity of pathways associated with psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579419001329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Developmental pathways to social anxiety and irritability: The role of the ERN [Texte imprimé et/ou numérique] / Courtney A. FILIPPI, Auteur ; Anni R. SUBAR, Auteur ; Jessica F. SACHS, Auteur ; Katharina KIRCANSKI, Auteur ; George BUZZELL, Auteur ; David PAGLIACCIO, Auteur ; Rany ABEND, Auteur ; Nathan A. FOX, Auteur ; Ellen LEIBENLUFT, Auteur ; Daniel S. PINE, Auteur . - p.897-907. Langues : Anglais (eng) in Development and Psychopathology > 32-3 (August 2020) . - p.897-907 Mots-clés : Ern  behavioral inhibition  developmental pathways  irritability  psychopathology Index. décimale : PER Périodiques Résumé : Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We tested whether error-related negativity (ERN) moderates the link between early behavior and later psychopathology in two early childhood phenotypes: behavioral inhibition and irritability. From ages 2 to 7 years, children (n = 291) were assessed longitudinally for behavioral inhibition (BI) and irritability. Behavioral inhibition was assessed via maternal report and behavioral responses to novelty. Childhood irritability was assessed using the Child Behavior Checklist. At age 12, an electroencephalogram (EEG) was recorded while children performed a flanker task to measure ERN, a neural indicator of error monitoring. Clinical assessments of anxiety and irritability were conducted using questionnaires (i.e., Screen for Child Anxiety Related Disorders and Affective Reactivity Index) and clinical interviews. Error monitoring interacted with early BI and early irritability to predict later psychopathology. Among children with high BI, an enhanced ERN predicted greater social anxiety at age 12. In contrast, children with high childhood irritability and blunted ERN predicted greater irritability at age 12. This converges with previous work and provides novel insight into the specificity of pathways associated with psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579419001329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

Developmental pathways to social anxiety and irritability: The role of the ERN – CORRIGENDUM / Courtney A. FILIPPI in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.1198-1200 Titre : Developmental pathways to social anxiety and irritability: The role of the ERN – CORRIGENDUM Type de document : Texte imprimé et/ou numérique Auteurs : Courtney A. FILIPPI, Auteur ; Anni R. SUBAR, Auteur ; Jessica F. SACHS, Auteur ; Katharina KIRCANSKI, Auteur ; George BUZZELL, Auteur ; David PAGLIACCIO, Auteur ; Rany ABEND, Auteur ; Nathan A. FOX, Auteur ; Ellen LEIBENLUFT, Auteur ; Daniel S. PINE, Auteur Article en page(s) : p.1198-1200 Langues : Anglais (eng) Mots-clés : behavioral inhibition  developmental pathways  ERN  irritability  psychopathology  corrigendum Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579421000316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Developmental pathways to social anxiety and irritability: The role of the ERN – CORRIGENDUM [Texte imprimé et/ou numérique] / Courtney A. FILIPPI, Auteur ; Anni R. SUBAR, Auteur ; Jessica F. SACHS, Auteur ; Katharina KIRCANSKI, Auteur ; George BUZZELL, Auteur ; David PAGLIACCIO, Auteur ; Rany ABEND, Auteur ; Nathan A. FOX, Auteur ; Ellen LEIBENLUFT, Auteur ; Daniel S. PINE, Auteur . - p.1198-1200. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.1198-1200 Mots-clés : behavioral inhibition  developmental pathways  ERN  irritability  psychopathology  corrigendum Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579421000316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

Neural sensitivity to peer feedback and depression symptoms in adolescents: a 2-year multiwave longitudinal study / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 64-2 (February 2023)  

Permalink

Prenatal exposure to air pollution and childhood internalizing problems: roles of shyness and anterior cingulate cortex activity / Ran LIU in Journal of Child Psychology and Psychiatry, 64-7 (July 2023)  

Permalink

Prenatal exposure to polycyclic aromatic hydrocarbons modifies the effects of early life stress on attention and Thought Problems in late childhood / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

Permalink

Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)  

Permalink

Testing the interpersonal theory of suicide in adolescents: A multi-wave longitudinal study / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)  

Permalink

---

1 (1 - 10 / 10)