Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior / Denis G SUKHODOLSKY in Autism, 24-2 (February 2020)  

Public ISBD [article]  inAutism > 24-2 (February 2020) . - p.400-410 Titre : Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior Type de document : Texte imprimé et/ou numérique Auteurs : Denis G SUKHODOLSKY, Auteur ; Luc LECAVALIER, Auteur ; Cynthia JOHNSON, Auteur ; Tristram SMITH, Auteur ; Naomi SWIEZY, Auteur ; Karen E. BEARSS, Auteur ; Carla B. KALVIN, Auteur ; Lawrence SCAHILL, Auteur Article en page(s) : p.400-410 Langues : Anglais (eng) Mots-clés : anxiety  autism  autism spectrum disorder  early childhood inventory  young children Index. décimale : PER Périodiques Résumé : Anxiety is a common and impairing problem in children with autism spectrum disorder, but little is known about it in preschool children with autism spectrum disorder. This article reports on the characteristics of anxiety symptoms in young children with autism spectrum disorder using a parent-completed rating scale. One hundred and eighty children (age 3-7 years) participated in a clinical trial of parent training for disruptive behaviors. Anxiety was measured as part of pre-treatment subject characterization with 16 items from the Early Childhood Inventory, a parent-completed scale on child psychiatric symptoms. Parents also completed other measures of behavioral problems. Sixty-seven percent of children were rated by their parents as having two or more clinically significant symptoms of anxiety. There were no differences in the Early Childhood Inventory anxiety severity scores of children with IQ < 70 and those with 70. Higher levels of anxiety were associated with severity of oppositional defiant behavior and social disability. Anxiety symptoms are common in preschoolers with autism spectrum disorder. These findings are consistent with earlier work in school-age children with autism spectrum disorder. There were no differences in anxiety between children with IQ below 70 and those with IQ of 70 and above. Social withdrawal and oppositional behavior were associated with anxiety in young children with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361319866561 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior [Texte imprimé et/ou numérique] / Denis G SUKHODOLSKY, Auteur ; Luc LECAVALIER, Auteur ; Cynthia JOHNSON, Auteur ; Tristram SMITH, Auteur ; Naomi SWIEZY, Auteur ; Karen E. BEARSS, Auteur ; Carla B. KALVIN, Auteur ; Lawrence SCAHILL, Auteur . - p.400-410. Langues : Anglais (eng) in Autism > 24-2 (February 2020) . - p.400-410 Mots-clés : anxiety  autism  autism spectrum disorder  early childhood inventory  young children Index. décimale : PER Périodiques Résumé : Anxiety is a common and impairing problem in children with autism spectrum disorder, but little is known about it in preschool children with autism spectrum disorder. This article reports on the characteristics of anxiety symptoms in young children with autism spectrum disorder using a parent-completed rating scale. One hundred and eighty children (age 3-7 years) participated in a clinical trial of parent training for disruptive behaviors. Anxiety was measured as part of pre-treatment subject characterization with 16 items from the Early Childhood Inventory, a parent-completed scale on child psychiatric symptoms. Parents also completed other measures of behavioral problems. Sixty-seven percent of children were rated by their parents as having two or more clinically significant symptoms of anxiety. There were no differences in the Early Childhood Inventory anxiety severity scores of children with IQ < 70 and those with 70. Higher levels of anxiety were associated with severity of oppositional defiant behavior and social disability. Anxiety symptoms are common in preschoolers with autism spectrum disorder. These findings are consistent with earlier work in school-age children with autism spectrum disorder. There were no differences in anxiety between children with IQ below 70 and those with IQ of 70 and above. Social withdrawal and oppositional behavior were associated with anxiety in young children with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361319866561 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index / Carla B. KALVIN in Journal of Autism and Developmental Disorders, 51-5 (May 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1496-1507 Titre : Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index Type de document : Texte imprimé et/ou numérique Auteurs : Carla B. KALVIN, Auteur ; Theresa R. GLADSTONE, Auteur ; Rebecca JORDAN, Auteur ; Sonia ROWLEY, Auteur ; Carolyn L. MARSH, Auteur ; Karim IBRAHIM, Auteur ; Denis G SUKHODOLSKY, Auteur Article en page(s) : p.1496-1507 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Irritability  Noncompliance  treatment manual on CBT for anger and aggression in children. Other authors (C.B.K.,  T.R.G., R.J., S.R., C.L.M. and K.I.) have no biomedical financial interests or  potential conflicts of interest to declare related to this present study. Index. décimale : PER Périodiques Résumé : Irritability is an impairing problem in children with ASD that may be associated with other behavioral and emotional concerns. The Affective Reactivity Index (ARI) is a parent-rated measure of irritability widely used in children with mood disorders, however, its utility in children with ASD remains unclear. In this study, we examined ARI parent ratings in children with ASD and contributions of parent-rated anxiety and noncompliance to irritability measured by the ARI. Participants included 81 children with ASD, aged 8-16 years. Results suggest that both anxiety and noncompliance contribute to irritability, but that anxiety only contributes to irritability in the absence of noncompliance. Further, the ARI is likely to be a useful measure of irritability in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04627-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 [article] Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index [Texte imprimé et/ou numérique] / Carla B. KALVIN, Auteur ; Theresa R. GLADSTONE, Auteur ; Rebecca JORDAN, Auteur ; Sonia ROWLEY, Auteur ; Carolyn L. MARSH, Auteur ; Karim IBRAHIM, Auteur ; Denis G SUKHODOLSKY, Auteur . - p.1496-1507. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1496-1507 Mots-clés : Anxiety  Autism spectrum disorder  Irritability  Noncompliance  treatment manual on CBT for anger and aggression in children. Other authors (C.B.K.,  T.R.G., R.J., S.R., C.L.M. and K.I.) have no biomedical financial interests or  potential conflicts of interest to declare related to this present study. Index. décimale : PER Périodiques Résumé : Irritability is an impairing problem in children with ASD that may be associated with other behavioral and emotional concerns. The Affective Reactivity Index (ARI) is a parent-rated measure of irritability widely used in children with mood disorders, however, its utility in children with ASD remains unclear. In this study, we examined ARI parent ratings in children with ASD and contributions of parent-rated anxiety and noncompliance to irritability measured by the ARI. Participants included 81 children with ASD, aged 8-16 years. Results suggest that both anxiety and noncompliance contribute to irritability, but that anxiety only contributes to irritability in the absence of noncompliance. Further, the ARI is likely to be a useful measure of irritability in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04627-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445

Discrepancies between parent and child ratings of anxiety in children with autism spectrum disorder / Carla B. KALVIN in Autism Research, 13-1 (January 2020)  

Public ISBD [article]  inAutism Research > 13-1 (January 2020) . - p.93-103 Titre : Discrepancies between parent and child ratings of anxiety in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Carla B. KALVIN, Auteur ; Carolyn L. MARSH, Auteur ; Karim IBRAHIM, Auteur ; Theresa R. GLADSTONE, Auteur ; Diana WOODWARD, Auteur ; Heidi GRANTZ, Auteur ; Pamela VENTOLA, Auteur ; Denis G SUKHODOLSKY, Auteur Article en page(s) : p.93-103 Langues : Anglais (eng) Mots-clés : anxiety  assessment  autism spectrum disorder  comorbidity  self-report Index. décimale : PER Périodiques Résumé : Co-occurring anxiety is common in children with autism spectrum disorder (ASD). However, inconsistencies across parent and child reports of anxiety may complicate the assessment of anxiety in this population. The present study examined parent and child anxiety ratings in children with ASD with and without anxiety disorders and tested the association between parent-child anxiety rating discrepancy and ASD symptom severity. Participants included children aged 8-16 years in three diagnostic groups: ASD with co-occurring anxiety disorders (ASD + Anxiety; n = 34), ASD without co-occurring anxiety disorders (ASD; n = 18), and typically developing healthy controls (TD; n = 50). Parents and children completed ratings of child anxiety using the Multidimensional Anxiety Rating Scale. Patterns of parent and child anxiety ratings differed among the three groups, with parent ratings exceeding child ratings only in the ASD + Anxiety group. Parents reported higher levels of child anxiety in the ASD + Anxiety versus ASD group, whereas children reported comparable levels of anxiety in the two groups. Among children with ASD, ASD symptom severity was positively associated with the degree to which parent ratings exceeded child ratings. Results suggest that children with ASD and co-occurring anxiety disorders endorse some anxiety symptoms but may underreport overall levels of anxiety. In addition, ASD symptom severity might increase discrepancies in parent-child anxiety ratings. These findings suggest a unique and valuable role of child anxiety ratings and suggest that both parent and child anxiety ratings should be considered in light of children's ASD symptom severity and used to guide further assessment. Autism Res 2020, 13: 93-103. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Children with autism spectrum disorder (ASD) commonly experience anxiety; yet, their perceptions of their anxiety might differ from their parents' perceptions. This study found that, while children with ASD and anxiety disorders acknowledge some anxiety, their parents report them as having higher levels of anxiety. Also, child and parent perceptions of anxiety may differ more for children with more severe ASD symptoms. How these findings may guide research and clinical practice is discussed. En ligne : http://dx.doi.org/10.1002/aur.2220 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] Discrepancies between parent and child ratings of anxiety in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Carla B. KALVIN, Auteur ; Carolyn L. MARSH, Auteur ; Karim IBRAHIM, Auteur ; Theresa R. GLADSTONE, Auteur ; Diana WOODWARD, Auteur ; Heidi GRANTZ, Auteur ; Pamela VENTOLA, Auteur ; Denis G SUKHODOLSKY, Auteur . - p.93-103. Langues : Anglais (eng) in Autism Research > 13-1 (January 2020) . - p.93-103 Mots-clés : anxiety  assessment  autism spectrum disorder  comorbidity  self-report Index. décimale : PER Périodiques Résumé : Co-occurring anxiety is common in children with autism spectrum disorder (ASD). However, inconsistencies across parent and child reports of anxiety may complicate the assessment of anxiety in this population. The present study examined parent and child anxiety ratings in children with ASD with and without anxiety disorders and tested the association between parent-child anxiety rating discrepancy and ASD symptom severity. Participants included children aged 8-16 years in three diagnostic groups: ASD with co-occurring anxiety disorders (ASD + Anxiety; n = 34), ASD without co-occurring anxiety disorders (ASD; n = 18), and typically developing healthy controls (TD; n = 50). Parents and children completed ratings of child anxiety using the Multidimensional Anxiety Rating Scale. Patterns of parent and child anxiety ratings differed among the three groups, with parent ratings exceeding child ratings only in the ASD + Anxiety group. Parents reported higher levels of child anxiety in the ASD + Anxiety versus ASD group, whereas children reported comparable levels of anxiety in the two groups. Among children with ASD, ASD symptom severity was positively associated with the degree to which parent ratings exceeded child ratings. Results suggest that children with ASD and co-occurring anxiety disorders endorse some anxiety symptoms but may underreport overall levels of anxiety. In addition, ASD symptom severity might increase discrepancies in parent-child anxiety ratings. These findings suggest a unique and valuable role of child anxiety ratings and suggest that both parent and child anxiety ratings should be considered in light of children's ASD symptom severity and used to guide further assessment. Autism Res 2020, 13: 93-103. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Children with autism spectrum disorder (ASD) commonly experience anxiety; yet, their perceptions of their anxiety might differ from their parents' perceptions. This study found that, while children with ASD and anxiety disorders acknowledge some anxiety, their parents report them as having higher levels of anxiety. Also, child and parent perceptions of anxiety may differ more for children with more severe ASD symptoms. How these findings may guide research and clinical practice is discussed. En ligne : http://dx.doi.org/10.1002/aur.2220 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials / Lawrence SCAHILL in Autism, 20-2 (February 2016)  

Public ISBD [article]  inAutism > 20-2 (February 2016) . - p.145-152 Titre : Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials Type de document : Texte imprimé et/ou numérique Auteurs : Lawrence SCAHILL, Auteur ; Denis G SUKHODOLSKY, Auteur ; Emily I. ANDERBERG, Auteur ; Anastasia DIMITROPOULOS, Auteur ; James DZIURA, Auteur ; Michael G. AMAN, Auteur ; James MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Victoria HALLETT, Auteur ; Karol KATZ, Auteur ; Benedetto VITIELLO, Auteur ; Christopher MCDOUGLE, Auteur Article en page(s) : p.145-152 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  clinical trials  outcome measurement  repetitive behavior  risperidone Index. décimale : PER Périodiques Résumé : Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder to detect change with treatment. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. In Study 2, 49 subjects received risperidone only and 75 subjects received risperidone plus parent training. The combined sample consisted of 187 boys and 38 girls (aged 4–17?years). At the medication-free baseline, the internal consistency on the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder total score was excellent (Cronbach’s alpha = 0.84) and the mean scores were similar across the four groups. Compared to placebo in Study 1, all three active treatment groups showed significant improvement (effect sizes: 0.74–0.88). There were no differences between active treatment groups. These results indicate that the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder has acceptable test–retest as evidenced by the medium to high correlations in the placebo group and demonstrated sensitivity to change with treatment. En ligne : http://dx.doi.org/10.1177/1362361315574889 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Sensitivity of the modified Children’s Yale–Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials [Texte imprimé et/ou numérique] / Lawrence SCAHILL, Auteur ; Denis G SUKHODOLSKY, Auteur ; Emily I. ANDERBERG, Auteur ; Anastasia DIMITROPOULOS, Auteur ; James DZIURA, Auteur ; Michael G. AMAN, Auteur ; James MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Victoria HALLETT, Auteur ; Karol KATZ, Auteur ; Benedetto VITIELLO, Auteur ; Christopher MCDOUGLE, Auteur . - p.145-152. Langues : Anglais (eng) in Autism > 20-2 (February 2016) . - p.145-152 Mots-clés : autism spectrum disorder  clinical trials  outcome measurement  repetitive behavior  risperidone Index. décimale : PER Périodiques Résumé : Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder to detect change with treatment. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. In Study 2, 49 subjects received risperidone only and 75 subjects received risperidone plus parent training. The combined sample consisted of 187 boys and 38 girls (aged 4–17?years). At the medication-free baseline, the internal consistency on the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder total score was excellent (Cronbach’s alpha = 0.84) and the mean scores were similar across the four groups. Compared to placebo in Study 1, all three active treatment groups showed significant improvement (effect sizes: 0.74–0.88). There were no differences between active treatment groups. These results indicate that the Children’s Yale–Brown Obsessive Compulsive Scale modified for autism spectrum disorder has acceptable test–retest as evidenced by the medium to high correlations in the placebo group and demonstrated sensitivity to change with treatment. En ligne : http://dx.doi.org/10.1177/1362361315574889 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

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