Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder / Marion RUTHERFORD in Autism, 20-5 (July 2016)  

Public ISBD [article]  inAutism > 20-5 (July 2016) . - p.628-634 Titre : Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; Tess JOHNSON, Auteur ; Ciara CATCHPOLE, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Deborah MCCARTNEY, Auteur ; Aja MURRAY, Auteur Article en page(s) : p.628-634 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  diagnosis  females  gender  males Index. décimale : PER Périodiques Résumé : This article reports on gender ratio, age of diagnosis and the duration of assessment procedures in autism spectrum disorder diagnosis in a national study which included all types of clinical services for children and adults. Findings are reported from a retrospective case note analysis undertaken with a representative sample of 150 Scottish children and adults recently diagnosed with autism spectrum disorder. The study reports key findings that the gender ratio in this consecutively referred cohort is lower than anticipated in some age groups and reduces with increasing age. The gender ratio in children, together with the significant difference in the mean age of referral and diagnosis for girls compared to boys, adds evidence of delayed recognition of autism spectrum disorder in younger girls. There was no significant difference in duration of assessment for males and females suggesting that delays in diagnosis of females occur prior to referral for assessment. Implications for practice and research are considered. En ligne : http://dx.doi.org/10.1177/1362361315617879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 [article] Gender ratio in a clinical population sample, age of diagnosis and duration of assessment in children and adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Marion RUTHERFORD, Auteur ; Karen MCKENZIE, Auteur ; Tess JOHNSON, Auteur ; Ciara CATCHPOLE, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Kirsty FORSYTH, Auteur ; Deborah MCCARTNEY, Auteur ; Aja MURRAY, Auteur . - p.628-634. Langues : Anglais (eng) in Autism > 20-5 (July 2016) . - p.628-634 Mots-clés : autism spectrum disorder  diagnosis  females  gender  males Index. décimale : PER Périodiques Résumé : This article reports on gender ratio, age of diagnosis and the duration of assessment procedures in autism spectrum disorder diagnosis in a national study which included all types of clinical services for children and adults. Findings are reported from a retrospective case note analysis undertaken with a representative sample of 150 Scottish children and adults recently diagnosed with autism spectrum disorder. The study reports key findings that the gender ratio in this consecutively referred cohort is lower than anticipated in some age groups and reduces with increasing age. The gender ratio in children, together with the significant difference in the mean age of referral and diagnosis for girls compared to boys, adds evidence of delayed recognition of autism spectrum disorder in younger girls. There was no significant difference in duration of assessment for males and females suggesting that delays in diagnosis of females occur prior to referral for assessment. Implications for practice and research are considered. En ligne : http://dx.doi.org/10.1177/1362361315617879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290

Prenatal maternal infections and early childhood developmental outcomes: analysis of linked administrative health data for Greater Glasgow & Clyde, Scotland / Iain HARDIE in Journal of Child Psychology and Psychiatry, 66-1 (January 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-1 (January 2025) . - p.30-40 Titre : Prenatal maternal infections and early childhood developmental outcomes: analysis of linked administrative health data for Greater Glasgow & Clyde, Scotland Type de document : Texte imprimé et/ou numérique Auteurs : Iain HARDIE, Auteur ; Aja MURRAY, Auteur ; Josiah KING, Auteur ; Hildigunnur Anna HALL, Auteur ; Emily LUEDECKE, Auteur ; Louise MARRYAT, Auteur ; Lucy THOMPSON, Auteur ; Helen MINNIS, Auteur ; Philip WILSON, Auteur ; Bonnie AUYEUNG, Auteur Article en page(s) : p.30-40 Langues : Anglais (eng) Mots-clés : Child development  maternal factors  prenatal  infection  CNS Index. décimale : PER Périodiques Résumé : Background Previous research has linked prenatal maternal infections to later childhood developmental outcomes and socioemotional difficulties. However, existing studies have relied on retrospectively self-reported survey data, or data on hospital-recorded infections only, resulting in gaps in data collection. Methods This study used a large linked administrative health dataset, bringing together data from birth records, hospital records, prescriptions and routine child health reviews for 55,856 children born in Greater Glasgow 95% CI: 1.19?1.42). This was broadly consistent across all developmental outcome types and appeared to be specifically linked to infections occurring in pregnancy trimesters 2 (OR: 1.34; 95% CI: 1.07?1.67) and 3 (OR: 1.33; 95% CI: 1.21?1.47), that is the trimesters in which foetal brain myelination occurs. Infection-related prescriptions were not associated with any clear increase in odds of having at least one developmental concern after confounder/covariate adjustment (OR: 1.03; 95% CI: 0.98?1.08), but were associated with slightly increased odds of concerns specifically related to personal-social (OR: 1.12; 95% CI: 1.03?1.22) and emotional-behavioural-attention (OR: 1.15; 95% CI: 1.08?1.22) development. Conclusions Prenatal infections, particularly those which are hospital-diagnosed (and likely more severe), are associated with early childhood developmental outcomes. Prevention of prenatal infections, and monitoring of support needs of affected children, may improve childhood development, but causality remains to be established. En ligne : https://dx.doi.org/10.1111/jcpp.14028 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Prenatal maternal infections and early childhood developmental outcomes: analysis of linked administrative health data for Greater Glasgow & Clyde, Scotland [Texte imprimé et/ou numérique] / Iain HARDIE, Auteur ; Aja MURRAY, Auteur ; Josiah KING, Auteur ; Hildigunnur Anna HALL, Auteur ; Emily LUEDECKE, Auteur ; Louise MARRYAT, Auteur ; Lucy THOMPSON, Auteur ; Helen MINNIS, Auteur ; Philip WILSON, Auteur ; Bonnie AUYEUNG, Auteur . - p.30-40. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-1 (January 2025) . - p.30-40 Mots-clés : Child development  maternal factors  prenatal  infection  CNS Index. décimale : PER Périodiques Résumé : Background Previous research has linked prenatal maternal infections to later childhood developmental outcomes and socioemotional difficulties. However, existing studies have relied on retrospectively self-reported survey data, or data on hospital-recorded infections only, resulting in gaps in data collection. Methods This study used a large linked administrative health dataset, bringing together data from birth records, hospital records, prescriptions and routine child health reviews for 55,856 children born in Greater Glasgow 95% CI: 1.19?1.42). This was broadly consistent across all developmental outcome types and appeared to be specifically linked to infections occurring in pregnancy trimesters 2 (OR: 1.34; 95% CI: 1.07?1.67) and 3 (OR: 1.33; 95% CI: 1.21?1.47), that is the trimesters in which foetal brain myelination occurs. Infection-related prescriptions were not associated with any clear increase in odds of having at least one developmental concern after confounder/covariate adjustment (OR: 1.03; 95% CI: 0.98?1.08), but were associated with slightly increased odds of concerns specifically related to personal-social (OR: 1.12; 95% CI: 1.03?1.22) and emotional-behavioural-attention (OR: 1.15; 95% CI: 1.08?1.22) development. Conclusions Prenatal infections, particularly those which are hospital-diagnosed (and likely more severe), are associated with early childhood developmental outcomes. Prevention of prenatal infections, and monitoring of support needs of affected children, may improve childhood development, but causality remains to be established. En ligne : https://dx.doi.org/10.1111/jcpp.14028 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years / Xin WANG in Autism Research, 15-9 (September 2022)  

Public ISBD [article]  inAutism Research > 15-9 (September 2022) . - p.1675-1685 Titre : Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years Type de document : Texte imprimé et/ou numérique Auteurs : Xin WANG, Auteur ; Mei-Xia DAI, Auteur ; Aja MURRAY, Auteur ; Si-Yu LIU, Auteur ; Jia-Jie CHEN, Auteur ; Li-Zi LIN, Auteur ; Jin JING, Auteur ; Bonnie AUYEUNG, Auteur Article en page(s) : p.1675-1685 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/psychology  Child  Empathy  Female  Humans  Intelligence  Male  Psychometrics  Reproducibility of Results  autism spectrum disorder  children  empathy quotient  gender differences  systemizing quotient Index. décimale : PER Périodiques Résumé : We aimed to validate the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in Mainland China, which can reflect the profiles of empathizing and systemizing, and describing specific characteristics of autism spectrum disorder (ASD) and gender-typical behaviors in general population. A total of 800 typically developing (TD) children, aged 4-12years was recruited initially with whose parents/guardians complete the measurements, and 782 TD children who met inclusion criteria were finally included. A 23-item three-factor EQ-C and a 22-item four-factor SQ-C was developed with good internal consistency (Omega total values of 0.87 and 0.86) and test-retest reliability (Pearson correlation coefficients of 0.82 and 0.69). In TD children, girls scored significantly higher on EQ-C (31.4Â+7.8 vs. 28.2Â+7.7) but there were no gender differences in SQ-C scores. TD children showed different cognitive styles (empathizing-dominant for girls with 42.6% identified as Type E; systemizing-dominant for boys with 40.7% identified as Type S). A further sample of 222 children with ASD indicated that they scored lower on EQ/SQ-C compared to TD children (13.2Â+5.1 vs. 29.7Â+7.9, 12.4Â+5.8 vs. 23.5Â+8.3) and were generally systemizing-dominant (Type S: 50.8% for boys and 64.0% for girls). Autistic children scored higher on the SQ-C in those without intellectual disability and with higher paternal education level and family income (14.2Â+6.1 vs. 10.9Â+5.0, 13.3Â+6.2 vs. 11.5Â+5.1, 13.7Â+5.6 vs. 11.9Â+5.8), while there were no differences in the EQ-C. This study indicated good reliability and validity of the Chinese version of EQ/SQ-C, which can be used in Chinese children with and without ASD. LAY SUMMARY: We developed the Chinese version of the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in 782 typically developing (TD) children aged 4-12years in Mainland China, yielding a 23-item, 3-factor EQ-C and a 22-item, 4-factor SQ-C with good psychometric properties. In TD children, we found gender difference only in scores of EQ-C. Further analyses of 222 autistic children indicated that differences were found in scores of SQ-C when considering their gender, intelligence and socio-economic status. En ligne : http://dx.doi.org/10.1002/aur.2743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 [article] Psychometric properties of the Chinese version of the children's empathy quotient and systemizing quotient: 4-12years [Texte imprimé et/ou numérique] / Xin WANG, Auteur ; Mei-Xia DAI, Auteur ; Aja MURRAY, Auteur ; Si-Yu LIU, Auteur ; Jia-Jie CHEN, Auteur ; Li-Zi LIN, Auteur ; Jin JING, Auteur ; Bonnie AUYEUNG, Auteur . - p.1675-1685. Langues : Anglais (eng) in Autism Research > 15-9 (September 2022) . - p.1675-1685 Mots-clés : Autism Spectrum Disorder/psychology  Child  Empathy  Female  Humans  Intelligence  Male  Psychometrics  Reproducibility of Results  autism spectrum disorder  children  empathy quotient  gender differences  systemizing quotient Index. décimale : PER Périodiques Résumé : We aimed to validate the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in Mainland China, which can reflect the profiles of empathizing and systemizing, and describing specific characteristics of autism spectrum disorder (ASD) and gender-typical behaviors in general population. A total of 800 typically developing (TD) children, aged 4-12years was recruited initially with whose parents/guardians complete the measurements, and 782 TD children who met inclusion criteria were finally included. A 23-item three-factor EQ-C and a 22-item four-factor SQ-C was developed with good internal consistency (Omega total values of 0.87 and 0.86) and test-retest reliability (Pearson correlation coefficients of 0.82 and 0.69). In TD children, girls scored significantly higher on EQ-C (31.4Â+7.8 vs. 28.2Â+7.7) but there were no gender differences in SQ-C scores. TD children showed different cognitive styles (empathizing-dominant for girls with 42.6% identified as Type E; systemizing-dominant for boys with 40.7% identified as Type S). A further sample of 222 children with ASD indicated that they scored lower on EQ/SQ-C compared to TD children (13.2Â+5.1 vs. 29.7Â+7.9, 12.4Â+5.8 vs. 23.5Â+8.3) and were generally systemizing-dominant (Type S: 50.8% for boys and 64.0% for girls). Autistic children scored higher on the SQ-C in those without intellectual disability and with higher paternal education level and family income (14.2Â+6.1 vs. 10.9Â+5.0, 13.3Â+6.2 vs. 11.5Â+5.1, 13.7Â+5.6 vs. 11.9Â+5.8), while there were no differences in the EQ-C. This study indicated good reliability and validity of the Chinese version of EQ/SQ-C, which can be used in Chinese children with and without ASD. LAY SUMMARY: We developed the Chinese version of the Children's Empathy Quotient (EQ-C) and Systemizing Quotient (SQ-C) in 782 typically developing (TD) children aged 4-12years in Mainland China, yielding a 23-item, 3-factor EQ-C and a 22-item, 4-factor SQ-C with good psychometric properties. In TD children, we found gender difference only in scores of EQ-C. Further analyses of 222 autistic children indicated that differences were found in scores of SQ-C when considering their gender, intelligence and socio-economic status. En ligne : http://dx.doi.org/10.1002/aur.2743 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483

The relationship between waiting times and ‘adherence’ to the Scottish Intercollegiate Guidelines Network 98 guideline in autism spectrum disorder diagnostic services in Scotland / Karen MCKENZIE in Autism, 20-4 (May 2016)  

Public ISBD [article]  inAutism > 20-4 (May 2016) . - p.395-401 Titre : The relationship between waiting times and ‘adherence’ to the Scottish Intercollegiate Guidelines Network 98 guideline in autism spectrum disorder diagnostic services in Scotland Type de document : Texte imprimé et/ou numérique Auteurs : Karen MCKENZIE, Auteur ; Kirsty FORSYTH, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Marion RUTHERFORD, Auteur ; Aja MURRAY, Auteur ; Linda IRVINE, Auteur Article en page(s) : p.395-401 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  clinical guidelines  diagnosis  Scottish Intercollegiate Guidelines Network  wait times Index. décimale : PER Périodiques Résumé : The aim of this study was to explore the extent to which the Scottish Intercollegiate Guidelines Network 98 guidelines on the assessment and diagnosis of autism spectrum disorder were adhered to in child autism spectrum disorder diagnostic services in Scotland and whether there was a significant relationship between routine practice which more closely reflected these recommendations (increased adherence) and increased waiting times. Retrospective, cross-sectional case note analysis was applied to data from 80 case notes. Adherence ranged from a possible 0 (no adherence) to 19 (full adherence). Overall, 17/22 of the recommendations were adhered to in over 50 of the 80 cases and in 70 or more cases for 11/22 of the recommendations, with a mean adherence score of 16 (standard deviation?=?1.9). No significant correlation was found between adherence and total wait time for untransformed (r?=?0.15, p?=?0.32) or transformed data (r?=?0.12, p?=?0.20). The results indicated that the assessment and diagnostic practices were consistent with the relevant Scottish Intercollegiate Guidelines Network 98 guideline recommendations. Increased adherence to the 19 included recommendations was not significantly related to increased total waiting times, indicating that the Scottish Intercollegiate Guidelines Network 98 recommendations have generally been integrated into practice, without a resultant increase in patient waits. En ligne : http://dx.doi.org/10.1177/1362361315586136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=287 [article] The relationship between waiting times and ‘adherence’ to the Scottish Intercollegiate Guidelines Network 98 guideline in autism spectrum disorder diagnostic services in Scotland [Texte imprimé et/ou numérique] / Karen MCKENZIE, Auteur ; Kirsty FORSYTH, Auteur ; Anne O’HARE, Auteur ; IAIN MCCLURE, Auteur ; Marion RUTHERFORD, Auteur ; Aja MURRAY, Auteur ; Linda IRVINE, Auteur . - p.395-401. Langues : Anglais (eng) in Autism > 20-4 (May 2016) . - p.395-401 Mots-clés : autism spectrum disorder  clinical guidelines  diagnosis  Scottish Intercollegiate Guidelines Network  wait times Index. décimale : PER Périodiques Résumé : The aim of this study was to explore the extent to which the Scottish Intercollegiate Guidelines Network 98 guidelines on the assessment and diagnosis of autism spectrum disorder were adhered to in child autism spectrum disorder diagnostic services in Scotland and whether there was a significant relationship between routine practice which more closely reflected these recommendations (increased adherence) and increased waiting times. Retrospective, cross-sectional case note analysis was applied to data from 80 case notes. Adherence ranged from a possible 0 (no adherence) to 19 (full adherence). Overall, 17/22 of the recommendations were adhered to in over 50 of the 80 cases and in 70 or more cases for 11/22 of the recommendations, with a mean adherence score of 16 (standard deviation?=?1.9). No significant correlation was found between adherence and total wait time for untransformed (r?=?0.15, p?=?0.32) or transformed data (r?=?0.12, p?=?0.20). The results indicated that the assessment and diagnostic practices were consistent with the relevant Scottish Intercollegiate Guidelines Network 98 guideline recommendations. Increased adherence to the 19 included recommendations was not significantly related to increased total waiting times, indicating that the Scottish Intercollegiate Guidelines Network 98 recommendations have generally been integrated into practice, without a resultant increase in patient waits. En ligne : http://dx.doi.org/10.1177/1362361315586136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=287

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