Autism Spectrum Disorder Prevalence in Children Aged 12-13 Years From the Longitudinal Study of Australian Children / Tamara MAY in Autism Research, 13-5 (May 2020)  

Public ISBD [article]  inAutism Research > 13-5 (May 2020) . - p.821-827 Titre : Autism Spectrum Disorder Prevalence in Children Aged 12-13 Years From the Longitudinal Study of Australian Children Type de document : Texte imprimé et/ou numérique Auteurs : Tamara MAY, Auteur ; Amanda BRIGNELL, Auteur ; Katrina WILLIAMS, Auteur Article en page(s) : p.821-827 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  emotional and behavioral problems  epidemiology  longitudinal  prevalence Index. décimale : PER Périodiques Résumé : This study aimed to provide an autism spectrum disorder (ASD) prevalence update from parent and teacher report using the Longitudinal Study of Australian Children (LSAC). The LSAC is a prospective cohort study of Australian children representative of the population with two cohorts: Kinder (birth year 1999/2000) and Birth cohort (birth year 2003/2004). Children in the Birth and Kinder cohort with parent- and teacher-reported ASD prevalence were compared to children without ASD. There were N = 3,381 (66%) responding in the Birth cohort at age 12 and N = 3,089 (62%) for the Kinder cohort at age 16. Quality of life was measured by the Pediatric Quality of Life Inventory, and emotional/behavior problems using the Strengths and Difficulties Questionnaire. Parent-reported ASD prevalence increased to 4.36% [95% CI 3.56-5.19] at age 12-13 years in the Birth cohort and 2.60% [95% CI 2.07-3.31] in the Kinder cohort. Kinder cohort ASD children had more parent- and teacher-reported social problems, and lower parent-reported social and psychosocial quality of life. As expected, parent-reported ASD prevalence continued to rise. The higher prevalence in the Birth cohort may relate to milder cases of ASD being diagnosed. Autism Res 2020, 13: 821-827. (c) 2020 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Parent-reported ASD prevalence in 2016 in 12-year-old children from the Birth cohort of the Longitudinal Study of Australian Children was 4.4%, and higher than the 2.6% in the earlier born Kinder cohort. The Birth cohort had a milder presentation with fewer social, emotional, and behavioral problems than the Kinder cohort. Milder cases of ASD are being diagnosed in Australia resulting in one of the highest reported prevalence rates in the world. En ligne : http://dx.doi.org/10.1002/aur.2286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 [article] Autism Spectrum Disorder Prevalence in Children Aged 12-13 Years From the Longitudinal Study of Australian Children [Texte imprimé et/ou numérique] / Tamara MAY, Auteur ; Amanda BRIGNELL, Auteur ; Katrina WILLIAMS, Auteur . - p.821-827. Langues : Anglais (eng) in Autism Research > 13-5 (May 2020) . - p.821-827 Mots-clés : autism spectrum disorder  emotional and behavioral problems  epidemiology  longitudinal  prevalence Index. décimale : PER Périodiques Résumé : This study aimed to provide an autism spectrum disorder (ASD) prevalence update from parent and teacher report using the Longitudinal Study of Australian Children (LSAC). The LSAC is a prospective cohort study of Australian children representative of the population with two cohorts: Kinder (birth year 1999/2000) and Birth cohort (birth year 2003/2004). Children in the Birth and Kinder cohort with parent- and teacher-reported ASD prevalence were compared to children without ASD. There were N = 3,381 (66%) responding in the Birth cohort at age 12 and N = 3,089 (62%) for the Kinder cohort at age 16. Quality of life was measured by the Pediatric Quality of Life Inventory, and emotional/behavior problems using the Strengths and Difficulties Questionnaire. Parent-reported ASD prevalence increased to 4.36% [95% CI 3.56-5.19] at age 12-13 years in the Birth cohort and 2.60% [95% CI 2.07-3.31] in the Kinder cohort. Kinder cohort ASD children had more parent- and teacher-reported social problems, and lower parent-reported social and psychosocial quality of life. As expected, parent-reported ASD prevalence continued to rise. The higher prevalence in the Birth cohort may relate to milder cases of ASD being diagnosed. Autism Res 2020, 13: 821-827. (c) 2020 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Parent-reported ASD prevalence in 2016 in 12-year-old children from the Birth cohort of the Longitudinal Study of Australian Children was 4.4%, and higher than the 2.6% in the earlier born Kinder cohort. The Birth cohort had a milder presentation with fewer social, emotional, and behavioral problems than the Kinder cohort. Milder cases of ASD are being diagnosed in Australia resulting in one of the highest reported prevalence rates in the world. En ligne : http://dx.doi.org/10.1002/aur.2286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422

Delineating the autistic phenotype in children with neurofibromatosis type 1 / A. K. CHISHOLM in Molecular Autism, 13 (2022)  

Public ISBD [article]  inMolecular Autism > 13 (2022) . - 3p. Titre : Delineating the autistic phenotype in children with neurofibromatosis type 1 Type de document : Texte imprimé et/ou numérique Auteurs : A. K. CHISHOLM, Auteur ; K. M. HAEBICH, Auteur ; N. A. PRIDE, Auteur ; K. S. WALSH, Auteur ; F. LAMI, Auteur ; A. URE, Auteur ; T. MALOOF, Auteur ; Amanda BRIGNELL, Auteur ; M. ROUEL, Auteur ; Y. GRANADER, Auteur ; A. MAIER, Auteur ; B. BARTON, Auteur ; H. DARKE, Auteur ; G. DABSCHECK, Auteur ; V. A. ANDERSON, Auteur ; K. WILLIAMS, Auteur ; K. N. NORTH, Auteur ; J. M. PAYNE, Auteur Article en page(s) : 3p. Langues : Anglais (eng) Mots-clés : Autism  Autism Diagnostic Interview-Revised (ADI-R)  Autism Diagnostic Observation Schedule-Second Edition (ADOS-2)  Autistic behaviours  Neurofibromatosis type 1 Index. décimale : PER Périodiques Résumé : BACKGROUND: Existing research has demonstrated elevated autistic behaviours in children with neurofibromatosis type 1 (NF1), but the autistic phenotype and its relationship to other neurodevelopmental manifestations of NF1 remains unclear. To address this gap, we performed detailed characterisation of autistic behaviours in children with NF1 and investigated their association with other common NF1 child characteristics. METHODS: Participants were drawn from a larger cross-sectional study examining autism in children with NF1. The population analysed in this study scored above threshold on the Social Responsiveness Scale-Second Edition (T-score???60; 51% larger cohort) and completed the Autism Diagnostic Interview-Revised (ADI-R) and/or the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). All participants underwent evaluation of their intellectual function, and behavioural data were collected via parent questionnaires. RESULTS: The study cohort comprised 68 children (3-15 years). Sixty-three per cent met the ADOS-2 'autism spectrum' cut-off, and 34% exceeded the more stringent threshold for 'autistic disorder' on the ADI-R. Social communication symptoms were common and wide-ranging, while restricted and repetitive behaviours (RRBs) were most commonly characterised by 'insistence on sameness' (IS) behaviours such as circumscribed interests and difficulties with minor changes. Autistic behaviours were weakly correlated with hyperactive/impulsive attention deficit hyperactivity disorder (ADHD) symptoms but not with inattentive ADHD or other behavioural characteristics. Language and verbal IQ were weakly related to social communication behaviours but not to RRBs. LIMITATIONS: Lack of genetic validation of NF1, no clinical diagnosis of autism, and a retrospective assessment of autistic behaviours in early childhood. CONCLUSIONS: Findings provide strong support for elevated autistic behaviours in children with NF1. While these behaviours were relatively independent of other NF1 comorbidities, the importance of taking broader child characteristics into consideration when interpreting data from autism-specific measures in this population is highlighted. Social communication deficits appear similar to those observed in idiopathic autism and are coupled with a unique RRB profile comprising prominent IS behaviours. This autistic phenotype and its relationship to common NF1 comorbidities such as anxiety and executive dysfunction will be important to examine in future research. Current findings have important implications for the early identification of autism in NF1 and clinical management. En ligne : http://dx.doi.org/10.1186/s13229-021-00481-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 [article] Delineating the autistic phenotype in children with neurofibromatosis type 1 [Texte imprimé et/ou numérique] / A. K. CHISHOLM, Auteur ; K. M. HAEBICH, Auteur ; N. A. PRIDE, Auteur ; K. S. WALSH, Auteur ; F. LAMI, Auteur ; A. URE, Auteur ; T. MALOOF, Auteur ; Amanda BRIGNELL, Auteur ; M. ROUEL, Auteur ; Y. GRANADER, Auteur ; A. MAIER, Auteur ; B. BARTON, Auteur ; H. DARKE, Auteur ; G. DABSCHECK, Auteur ; V. A. ANDERSON, Auteur ; K. WILLIAMS, Auteur ; K. N. NORTH, Auteur ; J. M. PAYNE, Auteur . - 3p. Langues : Anglais (eng) in Molecular Autism > 13 (2022) . - 3p. Mots-clés : Autism  Autism Diagnostic Interview-Revised (ADI-R)  Autism Diagnostic Observation Schedule-Second Edition (ADOS-2)  Autistic behaviours  Neurofibromatosis type 1 Index. décimale : PER Périodiques Résumé : BACKGROUND: Existing research has demonstrated elevated autistic behaviours in children with neurofibromatosis type 1 (NF1), but the autistic phenotype and its relationship to other neurodevelopmental manifestations of NF1 remains unclear. To address this gap, we performed detailed characterisation of autistic behaviours in children with NF1 and investigated their association with other common NF1 child characteristics. METHODS: Participants were drawn from a larger cross-sectional study examining autism in children with NF1. The population analysed in this study scored above threshold on the Social Responsiveness Scale-Second Edition (T-score???60; 51% larger cohort) and completed the Autism Diagnostic Interview-Revised (ADI-R) and/or the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). All participants underwent evaluation of their intellectual function, and behavioural data were collected via parent questionnaires. RESULTS: The study cohort comprised 68 children (3-15 years). Sixty-three per cent met the ADOS-2 'autism spectrum' cut-off, and 34% exceeded the more stringent threshold for 'autistic disorder' on the ADI-R. Social communication symptoms were common and wide-ranging, while restricted and repetitive behaviours (RRBs) were most commonly characterised by 'insistence on sameness' (IS) behaviours such as circumscribed interests and difficulties with minor changes. Autistic behaviours were weakly correlated with hyperactive/impulsive attention deficit hyperactivity disorder (ADHD) symptoms but not with inattentive ADHD or other behavioural characteristics. Language and verbal IQ were weakly related to social communication behaviours but not to RRBs. LIMITATIONS: Lack of genetic validation of NF1, no clinical diagnosis of autism, and a retrospective assessment of autistic behaviours in early childhood. CONCLUSIONS: Findings provide strong support for elevated autistic behaviours in children with NF1. While these behaviours were relatively independent of other NF1 comorbidities, the importance of taking broader child characteristics into consideration when interpreting data from autism-specific measures in this population is highlighted. Social communication deficits appear similar to those observed in idiopathic autism and are coupled with a unique RRB profile comprising prominent IS behaviours. This autistic phenotype and its relationship to common NF1 comorbidities such as anxiety and executive dysfunction will be important to examine in future research. Current findings have important implications for the early identification of autism in NF1 and clinical management. En ligne : http://dx.doi.org/10.1186/s13229-021-00481-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459

Is language ability associated with behaviors of concern in autism? A systematic review / Katrina WILLIAMS ; Tamara MAY ; Wei Herng WAN ; Amanda BRIGNELL in Autism Research, 16-2 (February 2023)  

Public ISBD [article]  inAutism Research > 16-2 (February 2023) . - p.250-270 Titre : Is language ability associated with behaviors of concern in autism? A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Katrina WILLIAMS, Auteur ; Tamara MAY, Auteur ; Wei Herng WAN, Auteur ; Amanda BRIGNELL, Auteur Article en page(s) : p.250-270 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract This review systematically synthesized evidence on the association between structural language ability and behaviors of concern (BoC) in autism. Four databases were searched for studies that included >10 autistic participants, measures of structural language (content and/or form of language) and BoC, and an analysis of their association. BoCs included self-injurious behavior (SIB), aggression, tantrums, and externalizing behavior. Methodological quality of studies were assessed using the Newcastle Ottawa Scale. Forty-five publications (n = 11,961) were included. Forty studies were cross-sectional and five were prospective cohort studies. Over 70% of the studies investigating expressive language and SIB (n = 10), aggression (n = 5), tantrums (n = 3), and externalizing behavior (n = 17) reported an inverse association, where lower expressive language ability was associated with increased BoC. Eleven out of sixteen studies of combined expressive and receptive language reported an inverse relationship with SIB or aggression. All outcomes were rated as moderate to very low certainty of evidence. This review highlights evidence showing an inverse association between expressive or combined language ability and SIB, and externalizing behavior in autism. However, further high-quality studies that use standardized, consistent measures of language and behavior and investigate longitudinal associations are needed. Early detection and support for reduced structural language difficulties have substantial potential to assist in reducing BoC. En ligne : https://doi.org/10.1002/aur.2855 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495 [article] Is language ability associated with behaviors of concern in autism? A systematic review [Texte imprimé et/ou numérique] / Katrina WILLIAMS, Auteur ; Tamara MAY, Auteur ; Wei Herng WAN, Auteur ; Amanda BRIGNELL, Auteur . - p.250-270. Langues : Anglais (eng) in Autism Research > 16-2 (February 2023) . - p.250-270 Index. décimale : PER Périodiques Résumé : Abstract This review systematically synthesized evidence on the association between structural language ability and behaviors of concern (BoC) in autism. Four databases were searched for studies that included >10 autistic participants, measures of structural language (content and/or form of language) and BoC, and an analysis of their association. BoCs included self-injurious behavior (SIB), aggression, tantrums, and externalizing behavior. Methodological quality of studies were assessed using the Newcastle Ottawa Scale. Forty-five publications (n = 11,961) were included. Forty studies were cross-sectional and five were prospective cohort studies. Over 70% of the studies investigating expressive language and SIB (n = 10), aggression (n = 5), tantrums (n = 3), and externalizing behavior (n = 17) reported an inverse association, where lower expressive language ability was associated with increased BoC. Eleven out of sixteen studies of combined expressive and receptive language reported an inverse relationship with SIB or aggression. All outcomes were rated as moderate to very low certainty of evidence. This review highlights evidence showing an inverse association between expressive or combined language ability and SIB, and externalizing behavior in autism. However, further high-quality studies that use standardized, consistent measures of language and behavior and investigate longitudinal associations are needed. Early detection and support for reduced structural language difficulties have substantial potential to assist in reducing BoC. En ligne : https://doi.org/10.1002/aur.2855 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495

Language growth in verbal autistic children from 5 to 11?years / Amanda BRIGNELL in Autism Research, 17-10 (October 2024)  

Public ISBD [article]  inAutism Research > 17-10 (October 2024) . - p.1994-2003 Titre : Language growth in verbal autistic children from 5 to 11?years Type de document : Texte imprimé et/ou numérique Auteurs : Amanda BRIGNELL, Auteur ; Katrina J. WILLIAMS, Auteur ; Sheena REILLY, Auteur ; Angela T. MORGAN, Auteur Article en page(s) : p.1994-2003 Langues : Anglais (eng) Mots-clés : autism  developmental language disorder  language  language impairment  language trajectory Index. décimale : PER Périodiques Résumé : Abstract To examine predictors and growth in language for verbal autistic and non-autistic children with/without low language from 4 to 11?years. Receptive and expressive language trajectories were compared in a community sample of 1026 children at ages 5, 7, and 11?years, across four groups: two autistic groups; one with and one without low language; and two non-autistic groups; one with and one without low language. Groups were delineated on baseline assessment at 4?years. Non-autistic and autistic children with low language had lower mean expressive language scores than the non-autistic typical language group (22.26 and 38.53?units lower, respectively, p? En ligne : https://doi.org/10.1002/aur.3171 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536 [article] Language growth in verbal autistic children from 5 to 11?years [Texte imprimé et/ou numérique] / Amanda BRIGNELL, Auteur ; Katrina J. WILLIAMS, Auteur ; Sheena REILLY, Auteur ; Angela T. MORGAN, Auteur . - p.1994-2003. Langues : Anglais (eng) in Autism Research > 17-10 (October 2024) . - p.1994-2003 Mots-clés : autism  developmental language disorder  language  language impairment  language trajectory Index. décimale : PER Périodiques Résumé : Abstract To examine predictors and growth in language for verbal autistic and non-autistic children with/without low language from 4 to 11?years. Receptive and expressive language trajectories were compared in a community sample of 1026 children at ages 5, 7, and 11?years, across four groups: two autistic groups; one with and one without low language; and two non-autistic groups; one with and one without low language. Groups were delineated on baseline assessment at 4?years. Non-autistic and autistic children with low language had lower mean expressive language scores than the non-autistic typical language group (22.26 and 38.53?units lower, respectively, p? En ligne : https://doi.org/10.1002/aur.3171 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536

Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder / Karen CHENAUSKY in Autism & Developmental Language Impairments, 4 (January-December 2019)  

Public ISBD [article]  inAutism & Developmental Language Impairments > 4 (January-December 2019) Titre : Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Karen CHENAUSKY, Auteur ; Amanda BRIGNELL, Auteur ; Angela MORGAN, Auteur ; Helen TAGER-FLUSBERG, Auteur Index. décimale : PER Périodiques Résumé : Background and aimsDevelopmental motor speech impairment has been suspected, but rarely systematically examined, in low- and minimally verbal individuals with autism spectrum disorder. We aimed to investigate the extent of motor speech impairment in this population and its relation to number of different words produced during a semi-structured language sample.MethodsVideos of 54 low-verbal and minimally verbal individuals (ages 4;4?18;10) performing portions of a speech praxis test were coded for signs of motor speech impairment (e.g., childhood apraxia of speech). Age, autism spectrum disorder severity, nonspeech oral-motor ability, speech production ability, nonverbal IQ, and receptive vocabulary were compared between groups.ResultsFour groups emerged: (1) speech within normal limits (n=12), (2) non-childhood apraxia of speech impairment (n=16), (3) suspected childhood apraxia of speech (n=13), and (4) insufficient speech to rate (n=13). Groups differed significantly in nonspeech oral-motor ability, speech production ability, nonverbal IQ, and receptive vocabulary. Overall, only speech production ability and receptive vocabulary accounted for significant variance in number of different words. Receptive vocabulary significantly predicted number of different words only in Groups 1 and 2, while speech production ability significantly predicted number of different words only in Groups 3 and 4.Conclusions and implicationsIf replicated, our findings have important implications for developing much-needed spoken language interventions in minimally verbal individuals with autism spectrum disorder. En ligne : https://doi.org/10.1177/2396941519856333 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / Karen CHENAUSKY, Auteur ; Amanda BRIGNELL, Auteur ; Angela MORGAN, Auteur ; Helen TAGER-FLUSBERG, Auteur. in Autism & Developmental Language Impairments > 4 (January-December 2019) Index. décimale : PER Périodiques Résumé : Background and aimsDevelopmental motor speech impairment has been suspected, but rarely systematically examined, in low- and minimally verbal individuals with autism spectrum disorder. We aimed to investigate the extent of motor speech impairment in this population and its relation to number of different words produced during a semi-structured language sample.MethodsVideos of 54 low-verbal and minimally verbal individuals (ages 4;4?18;10) performing portions of a speech praxis test were coded for signs of motor speech impairment (e.g., childhood apraxia of speech). Age, autism spectrum disorder severity, nonspeech oral-motor ability, speech production ability, nonverbal IQ, and receptive vocabulary were compared between groups.ResultsFour groups emerged: (1) speech within normal limits (n=12), (2) non-childhood apraxia of speech impairment (n=16), (3) suspected childhood apraxia of speech (n=13), and (4) insufficient speech to rate (n=13). Groups differed significantly in nonspeech oral-motor ability, speech production ability, nonverbal IQ, and receptive vocabulary. Overall, only speech production ability and receptive vocabulary accounted for significant variance in number of different words. Receptive vocabulary significantly predicted number of different words only in Groups 1 and 2, while speech production ability significantly predicted number of different words only in Groups 3 and 4.Conclusions and implicationsIf replicated, our findings have important implications for developing much-needed spoken language interventions in minimally verbal individuals with autism spectrum disorder. En ligne : https://doi.org/10.1177/2396941519856333 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder / Karen CHENAUSKY in Autism & Developmental Language Impairments, 4 (January-December 2019)  

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No Differences in Code-Related Emergent Literacy Skills in Well-Matched 4-Year-Old Children With and Without ASD / Marleen F. WESTERVELD in Journal of Autism and Developmental Disorders, 50-8 (August 2020)  

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Parent-reported Autism Diagnostic Stability and Trajectories in the Longitudinal Study of Australian Children / Tamara MAY in Autism Research, 14-4 (April 2021)  

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Parent-reported patterns of loss and gain in communication in 1- to 2-year-old children are not unique to autism spectrum disorder / Amanda BRIGNELL in Autism, 21-2 (February 2017)  

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Parent-reported patterns of loss and gain in communication in 1- to 2-year-old children are not unique to autism spectrum disorder / Amanda BRIGNELL in Autism, 21-3 (April 2017)  

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Patterns and Predictors of Language Development from 4 to 7 Years in Verbal Children With and Without Autism Spectrum Disorder / Amanda BRIGNELL in Journal of Autism and Developmental Disorders, 48-10 (October 2018)  

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Predictors and growth in receptive vocabulary from 4 to 8 years in children with and without autism spectrum disorder: A population-based study / Amanda BRIGNELL in Autism, 23-5 (July 2019)  

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Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1 / Anita K. CHISHOLM in Journal of Autism and Developmental Disorders, 53-7 (July 2023)  

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A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder / Amanda BRIGNELL in Autism & Developmental Language Impairments, 3 (January-December 2018)  

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