Brief Report: Sexual Orientation in Individuals with Autistic Traits: Population Based Study of 47,000 Adults in Stockholm County / Christiane E.S. RUDOLPH in Journal of Autism and Developmental Disorders, 48-2 (February 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-2 (February 2018) . - p.619-624 Titre : Brief Report: Sexual Orientation in Individuals with Autistic Traits: Population Based Study of 47,000 Adults in Stockholm County Type de document : texte imprimé Auteurs : Christiane E.S. RUDOLPH, Auteur ; Andreas LUNDIN, Auteur ; J.W. Ã…HS, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur Article en page(s) : p.619-624 Langues : Anglais (eng) Mots-clés : Aq-10  Bisexuality  Epidemiology  Homosexuality  Sexual orientation Index. décimale : PER Périodiques Résumé : We examined the association between autistic traits and sexual orientation in a general adult population (N = 47,356). Autistic traits were measured with the ten items Autistic Quotient questionnaire using a cut-off score of >/= 6. Sexual orientation was assessed by self-report. Multinomial logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for sexual orientation categories. Participants with autistic traits were more likely to identify as bisexual (OR 1.73; 95% CI 1.01-2.9) and to feel that their sexual orientation could neither be described as hetero-, homo- nor bisexual (OR 3.05; 95% CI 2.56-3.63), compared to individuals without autistic traits. Autistic traits are associated with minority sexual orientation, and perhaps with uncertain self-identification and/or a defiance of traditional ways of categorizing sexual identity. En ligne : https://doi.org/10.1007/s10803-017-3369-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=338 [article] Brief Report: Sexual Orientation in Individuals with Autistic Traits: Population Based Study of 47,000 Adults in Stockholm County [texte imprimé] / Christiane E.S. RUDOLPH, Auteur ; Andreas LUNDIN, Auteur ; J.W. Ã…HS, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur . - p.619-624. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-2 (February 2018) . - p.619-624 Mots-clés : Aq-10  Bisexuality  Epidemiology  Homosexuality  Sexual orientation Index. décimale : PER Périodiques Résumé : We examined the association between autistic traits and sexual orientation in a general adult population (N = 47,356). Autistic traits were measured with the ten items Autistic Quotient questionnaire using a cut-off score of >/= 6. Sexual orientation was assessed by self-report. Multinomial logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for sexual orientation categories. Participants with autistic traits were more likely to identify as bisexual (OR 1.73; 95% CI 1.01-2.9) and to feel that their sexual orientation could neither be described as hetero-, homo- nor bisexual (OR 3.05; 95% CI 2.56-3.63), compared to individuals without autistic traits. Autistic traits are associated with minority sexual orientation, and perhaps with uncertain self-identification and/or a defiance of traditional ways of categorizing sexual identity. En ligne : https://doi.org/10.1007/s10803-017-3369-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=338

Maternal hirsutism and autism spectrum disorders in offspring / Brian K. LEE in Autism Research, 10-9 (September 2017)  

Public ISBD [article]  inAutism Research > 10-9 (September 2017) . - p.1544-1546 Titre : Maternal hirsutism and autism spectrum disorders in offspring Type de document : texte imprimé Auteurs : Brian K. LEE, Auteur ; Stefan ARVER, Auteur ; Linnea WIDMAN, Auteur ; Renee M. GARDNER, Auteur ; Cecilia MAGNUSSON, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur Article en page(s) : p.1544-1546 Langues : Anglais (eng) Mots-clés : epidemiology - analytic (risk factors)  pre- and perinatal risk factors  environmental risk factors Index. décimale : PER Périodiques Résumé : Because animal and human studies indicate that androgen exposure can influence neurodevelopment, it has been hypothesized that prenatal exposure to excess androgens may predispose to disorders with male-skewed ratio such as autism spectrum disorders (ASD). Therefore, maternal conditions characterized by hyperandrogenism such as polycystic ovary syndrome (PCOS) or hirsutism may be relevant to child ASD. We previously found in a large Swedish case-control study of 23,748 ASD cases and 208,796 matched controls that PCOS in mothers is associated with increased offspring risk of ASD. In the same sample, we have now examined whether maternal diagnoses of hirsutism were associated with ASD. In both unadjusted logistic regression models and models adjusted for a variety of covariates, hirsutism was associated with higher odds of ASD. The most adjusted odds ratios for associations with ASD for hirsutism diagnosis before birth and lifetime diagnosis of hirsutism were 1.64 (95% CI: 0.94, 2.83) and 1.26 (95% CI: 1.01, 1.57), respectively. The presence of an association of maternal hirsutism with child ASD is consistent with the hypothesis that androgens may be involved in the etiology of ASD. En ligne : http://dx.doi.org/10.1002/aur.1797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320 [article] Maternal hirsutism and autism spectrum disorders in offspring [texte imprimé] / Brian K. LEE, Auteur ; Stefan ARVER, Auteur ; Linnea WIDMAN, Auteur ; Renee M. GARDNER, Auteur ; Cecilia MAGNUSSON, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur . - p.1544-1546. Langues : Anglais (eng) in Autism Research > 10-9 (September 2017) . - p.1544-1546 Mots-clés : epidemiology - analytic (risk factors)  pre- and perinatal risk factors  environmental risk factors Index. décimale : PER Périodiques Résumé : Because animal and human studies indicate that androgen exposure can influence neurodevelopment, it has been hypothesized that prenatal exposure to excess androgens may predispose to disorders with male-skewed ratio such as autism spectrum disorders (ASD). Therefore, maternal conditions characterized by hyperandrogenism such as polycystic ovary syndrome (PCOS) or hirsutism may be relevant to child ASD. We previously found in a large Swedish case-control study of 23,748 ASD cases and 208,796 matched controls that PCOS in mothers is associated with increased offspring risk of ASD. In the same sample, we have now examined whether maternal diagnoses of hirsutism were associated with ASD. In both unadjusted logistic regression models and models adjusted for a variety of covariates, hirsutism was associated with higher odds of ASD. The most adjusted odds ratios for associations with ASD for hirsutism diagnosis before birth and lifetime diagnosis of hirsutism were 1.64 (95% CI: 0.94, 2.83) and 1.26 (95% CI: 1.01, 1.57), respectively. The presence of an association of maternal hirsutism with child ASD is consistent with the hypothesis that androgens may be involved in the etiology of ASD. En ligne : http://dx.doi.org/10.1002/aur.1797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320

Measuring Autism Traits in the Adult General Population with the Brief Autism-Spectrum Quotient, AQ-10: Findings from the Stockholm Public Health Cohort / Andreas LUNDIN in Journal of Autism and Developmental Disorders, 49-2 (February 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-2 (February 2019) . - p.773-780 Titre : Measuring Autism Traits in the Adult General Population with the Brief Autism-Spectrum Quotient, AQ-10: Findings from the Stockholm Public Health Cohort Type de document : texte imprimé Auteurs : Andreas LUNDIN, Auteur ; Kyriaki KOSIDOU, Auteur ; Christina DALMAN, Auteur Article en page(s) : p.773-780 Langues : Anglais (eng) Mots-clés : Attention switching  Attention to details  Autistic traits  Imagination  Routine  Social skills Index. décimale : PER Périodiques Résumé : BACKGROUND: The autism-spectrum quotient scale was developed to study autism as a spectrum. Few studies have examined the psychometric properties of the 10 item AQ (AQ-10). We examine the AQ-10 measurement ability and convergent validity in a population health survey (n = 44,722). METHODS: The item severity and item discrimination was assessed using item response theory. Convergent validity was assessed by regressing on ADHD, psychological distress (PD) and having an education in the sciences. RESULTS: Whilst unidimensional, the AQ-10 had some poorly fitting items. Item discrimination ranged from very low to very high. The scale correlated as hypothesised with the regress expected when factoring in ADHD, PD and possessing an eduction in the sciences. CONCLUSION: The AQ-10 has adequate validity in the present sample and may be used in s as a measure of autistic traits. In Conclusion, The AQ-10 has adequate validity to be used in health surveys as a measure of autistic traits, although some items may perform poorly. En ligne : http://dx.doi.org/10.1007/s10803-018-3749-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382 [article] Measuring Autism Traits in the Adult General Population with the Brief Autism-Spectrum Quotient, AQ-10: Findings from the Stockholm Public Health Cohort [texte imprimé] / Andreas LUNDIN, Auteur ; Kyriaki KOSIDOU, Auteur ; Christina DALMAN, Auteur . - p.773-780. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-2 (February 2019) . - p.773-780 Mots-clés : Attention switching  Attention to details  Autistic traits  Imagination  Routine  Social skills Index. décimale : PER Périodiques Résumé : BACKGROUND: The autism-spectrum quotient scale was developed to study autism as a spectrum. Few studies have examined the psychometric properties of the 10 item AQ (AQ-10). We examine the AQ-10 measurement ability and convergent validity in a population health survey (n = 44,722). METHODS: The item severity and item discrimination was assessed using item response theory. Convergent validity was assessed by regressing on ADHD, psychological distress (PD) and having an education in the sciences. RESULTS: Whilst unidimensional, the AQ-10 had some poorly fitting items. Item discrimination ranged from very low to very high. The scale correlated as hypothesised with the regress expected when factoring in ADHD, PD and possessing an eduction in the sciences. CONCLUSION: The AQ-10 has adequate validity in the present sample and may be used in s as a measure of autistic traits. In Conclusion, The AQ-10 has adequate validity to be used in health surveys as a measure of autistic traits, although some items may perform poorly. En ligne : http://dx.doi.org/10.1007/s10803-018-3749-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382

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