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Auteur T. KATAYAMA |
Documents disponibles écrits par cet auteur (1)
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Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults / T. FUJIOKA in Molecular Autism, 7 (2016)
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Titre : Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults Type de document : Texte imprimé et/ou numérique Auteurs : T. FUJIOKA, Auteur ; K. INOHARA, Auteur ; Y. OKAMOTO, Auteur ; Y. MASUYA, Auteur ; M. ISHITOBI, Auteur ; Daisuke N. SAITO, Auteur ; M. JUNG, Auteur ; Sumiyoshi ARAI, Auteur ; Y. MATSUMURA, Auteur ; T. X. FUJISAWA, Auteur ; K. NARITA, Auteur ; K. SUZUKI, Auteur ; K. J. TSUCHIYA, Auteur ; N. MORI, Auteur ; T. KATAYAMA, Auteur ; M. SATO, Auteur ; T. MUNESUE, Auteur ; H. OKAZAWA, Auteur ; A. TOMODA, Auteur ; Y. WADA, Auteur ; H. KOSAKA, Auteur Article en page(s) : 19p. Langues : Anglais (eng) Mots-clés : Adolescent Adult Area Under Curve Autism Spectrum Disorder/diagnosis/physiopathology Case-Control Studies Discriminant Analysis Fixation, Ocular/physiology Humans Male Ocular Physiological Phenomena Photic Stimulation Psychometrics ROC Curve Social Behavior Time Factors Autism spectrum disorder Biological motion Eye-tracking Face Fixation Gaze abnormality Geometry Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, an all-in-one eye-tracking system for early detection of ASD in toddlers. Because abnormal gaze patterns have been documented in various ASD age groups, we predicted that Gazefinder might also detect gaze abnormality in adolescents and adults. In this study, we tested whether Gazefinder could identify unique gaze patterns in adolescents and adults with ASD. METHODS: We measured the percentage of eye fixation time allocated to particular objects depicted in movies (i.e., eyes and mouth in human face movies, upright and inverted biological motion in movies that presented these stimuli simultaneously, and people and geometry in movies that presented these stimuli simultaneously) by male adolescents and adults with ASD (N = 26) and age-matched males with typical development (TD; N = 35). We compared these percentages between the two groups (ASD and TD) and with scores on the social responsiveness scale (SRS). Further, we conducted discriminant analyses to determine if fixation times allocated to particular objects could be used to discriminate between individuals with and without ASD. RESULTS: Compared with the TD group, the ASD group showed significantly less fixation time at locations of salient social information (i.e., eyes in the movie of human faces without lip movement and people in the movie of people and geometry), while there were no significant groupwise differences in the responses to movies of human faces with lip movement or biological motion. In a within-group correlation analysis, a few of the fixation-time items correlated with SRS, although most of them did not. No items significantly correlated with SRS in both ASD and TD groups. The percentage fixation times to eyes and people, which exhibited large effect sizes for the group difference, could differentiate ASD and TD with a sensitivity of 81.0% and a specificity of 80.0%. CONCLUSIONS: These findings suggest that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults. En ligne : http://dx.doi.org/10.1186/s13229-016-0083-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328
in Molecular Autism > 7 (2016) . - 19p.[article] Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults [Texte imprimé et/ou numérique] / T. FUJIOKA, Auteur ; K. INOHARA, Auteur ; Y. OKAMOTO, Auteur ; Y. MASUYA, Auteur ; M. ISHITOBI, Auteur ; Daisuke N. SAITO, Auteur ; M. JUNG, Auteur ; Sumiyoshi ARAI, Auteur ; Y. MATSUMURA, Auteur ; T. X. FUJISAWA, Auteur ; K. NARITA, Auteur ; K. SUZUKI, Auteur ; K. J. TSUCHIYA, Auteur ; N. MORI, Auteur ; T. KATAYAMA, Auteur ; M. SATO, Auteur ; T. MUNESUE, Auteur ; H. OKAZAWA, Auteur ; A. TOMODA, Auteur ; Y. WADA, Auteur ; H. KOSAKA, Auteur . - 19p.
Langues : Anglais (eng)
in Molecular Autism > 7 (2016) . - 19p.
Mots-clés : Adolescent Adult Area Under Curve Autism Spectrum Disorder/diagnosis/physiopathology Case-Control Studies Discriminant Analysis Fixation, Ocular/physiology Humans Male Ocular Physiological Phenomena Photic Stimulation Psychometrics ROC Curve Social Behavior Time Factors Autism spectrum disorder Biological motion Eye-tracking Face Fixation Gaze abnormality Geometry Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, an all-in-one eye-tracking system for early detection of ASD in toddlers. Because abnormal gaze patterns have been documented in various ASD age groups, we predicted that Gazefinder might also detect gaze abnormality in adolescents and adults. In this study, we tested whether Gazefinder could identify unique gaze patterns in adolescents and adults with ASD. METHODS: We measured the percentage of eye fixation time allocated to particular objects depicted in movies (i.e., eyes and mouth in human face movies, upright and inverted biological motion in movies that presented these stimuli simultaneously, and people and geometry in movies that presented these stimuli simultaneously) by male adolescents and adults with ASD (N = 26) and age-matched males with typical development (TD; N = 35). We compared these percentages between the two groups (ASD and TD) and with scores on the social responsiveness scale (SRS). Further, we conducted discriminant analyses to determine if fixation times allocated to particular objects could be used to discriminate between individuals with and without ASD. RESULTS: Compared with the TD group, the ASD group showed significantly less fixation time at locations of salient social information (i.e., eyes in the movie of human faces without lip movement and people in the movie of people and geometry), while there were no significant groupwise differences in the responses to movies of human faces with lip movement or biological motion. In a within-group correlation analysis, a few of the fixation-time items correlated with SRS, although most of them did not. No items significantly correlated with SRS in both ASD and TD groups. The percentage fixation times to eyes and people, which exhibited large effect sizes for the group difference, could differentiate ASD and TD with a sensitivity of 81.0% and a specificity of 80.0%. CONCLUSIONS: These findings suggest that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults. En ligne : http://dx.doi.org/10.1186/s13229-016-0083-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328