Disconnection from others in autism is more than just a feeling: whole-brain neural synchrony in adults during implicit processing of emotional faces / R. MENNELLA in Molecular Autism, 8 (2017)  

Public ISBD [article]  inMolecular Autism > 8 (2017) . - 7p. Titre : Disconnection from others in autism is more than just a feeling: whole-brain neural synchrony in adults during implicit processing of emotional faces Type de document : Texte imprimé et/ou numérique Auteurs : R. MENNELLA, Auteur ; R. C. LEUNG, Auteur ; M. J. TAYLOR, Auteur ; B. T. DUNKLEY, Auteur Article en page(s) : 7p. Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/*psychology  Brain/*physiology  Brain Mapping/*methods  Facial Expression  Female  Humans  Image Processing, Computer-Assisted  Magnetoencephalography/*methods  Male  Social Perception  Young Adult  *Autism  *Emotional faces  *Functional connectivity  *Magnetoencephalography  *Social brain  *Young adults Index. décimale : PER Périodiques Résumé : BACKGROUND: Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the "social brain". Nonetheless, a whole-brain characterization of the fast responses in functional connectivity during implicit processing of emotional faces in adults with ASD is lacking. METHODS: The present study used magnetoencephalography to investigate early responses in functional connectivity, as measured by interregional phase synchronization, during implicit processing of angry, neutral and happy faces. The sample (n = 44) consisted of 22 young adults with ASD and 22 age- and sex-matched typically developed (TD) controls. RESULTS: Reduced phase-synchrony in the beta band around 300 ms emerged during processing of angry faces in the ASD compared to TD group, involving key areas of the social brain. In the same time window, de-synchronization in the beta band in the amygdala was reduced in the ASD group across conditions. CONCLUSIONS: This is the first demonstration of atypical global and local synchrony patterns in the social brain in adults with ASD during implicit processing of emotional faces. The present results replicate and substantially extend previous findings on adolescents, highlighting that atypical brain synchrony during processing of socio-emotional stimuli is a hallmark of clinical sequelae in autism. En ligne : http://dx.doi.org/10.1186/s13229-017-0123-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=330 [article] Disconnection from others in autism is more than just a feeling: whole-brain neural synchrony in adults during implicit processing of emotional faces [Texte imprimé et/ou numérique] / R. MENNELLA, Auteur ; R. C. LEUNG, Auteur ; M. J. TAYLOR, Auteur ; B. T. DUNKLEY, Auteur . - 7p. Langues : Anglais (eng) in Molecular Autism > 8 (2017) . - 7p. Mots-clés : Adult  Autism Spectrum Disorder/*psychology  Brain/*physiology  Brain Mapping/*methods  Facial Expression  Female  Humans  Image Processing, Computer-Assisted  Magnetoencephalography/*methods  Male  Social Perception  Young Adult  *Autism  *Emotional faces  *Functional connectivity  *Magnetoencephalography  *Social brain  *Young adults Index. décimale : PER Périodiques Résumé : BACKGROUND: Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the "social brain". Nonetheless, a whole-brain characterization of the fast responses in functional connectivity during implicit processing of emotional faces in adults with ASD is lacking. METHODS: The present study used magnetoencephalography to investigate early responses in functional connectivity, as measured by interregional phase synchronization, during implicit processing of angry, neutral and happy faces. The sample (n = 44) consisted of 22 young adults with ASD and 22 age- and sex-matched typically developed (TD) controls. RESULTS: Reduced phase-synchrony in the beta band around 300 ms emerged during processing of angry faces in the ASD compared to TD group, involving key areas of the social brain. In the same time window, de-synchronization in the beta band in the amygdala was reduced in the ASD group across conditions. CONCLUSIONS: This is the first demonstration of atypical global and local synchrony patterns in the social brain in adults with ASD during implicit processing of emotional faces. The present results replicate and substantially extend previous findings on adolescents, highlighting that atypical brain synchrony during processing of socio-emotional stimuli is a hallmark of clinical sequelae in autism. En ligne : http://dx.doi.org/10.1186/s13229-017-0123-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=330

Enhanced Early Visual Responses During Implicit Emotional Faces Processing in Autism Spectrum Disorder / K. KOVARSKI in Journal of Autism and Developmental Disorders, 49-3 (March 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.871-886 Titre : Enhanced Early Visual Responses During Implicit Emotional Faces Processing in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : K. KOVARSKI, Auteur ; R. MENNELLA, Auteur ; S. M. WONG, Auteur ; B. T. DUNKLEY, Auteur ; M. J. TAYLOR, Auteur ; Magali BATTY, Auteur Article en page(s) : p.871-886 Langues : Anglais (eng) Mots-clés : Autism  Emotion  Face processing  Meg  Visual processing Index. décimale : PER Périodiques Résumé : Research on Autism Spectrum Disorder (ASD) has focused on processing of socially-relevant stimuli, such as faces. Nonetheless, before being 'social', faces are visual stimuli. The present magnetoencephalography study investigated the time course of brain activity during an implicit emotional task in visual emotion-related regions in 19 adults with ASD (mean age 26.3 +/- 4.4) and 19 typically developed controls (26.4 +/- 4). The results confirmed previously-reported differences between groups in brain responses to emotion and a hypo-activation in the ASD group in the right fusiform gyrus around 150 ms. However, the ASD group also presented early enhanced activity in the occipital region. These results support that impaired face processing in ASD might be sustained by atypical responses in primary visual areas. En ligne : http://dx.doi.org/10.1007/s10803-018-3787-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Enhanced Early Visual Responses During Implicit Emotional Faces Processing in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / K. KOVARSKI, Auteur ; R. MENNELLA, Auteur ; S. M. WONG, Auteur ; B. T. DUNKLEY, Auteur ; M. J. TAYLOR, Auteur ; Magali BATTY, Auteur . - p.871-886. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.871-886 Mots-clés : Autism  Emotion  Face processing  Meg  Visual processing Index. décimale : PER Périodiques Résumé : Research on Autism Spectrum Disorder (ASD) has focused on processing of socially-relevant stimuli, such as faces. Nonetheless, before being 'social', faces are visual stimuli. The present magnetoencephalography study investigated the time course of brain activity during an implicit emotional task in visual emotion-related regions in 19 adults with ASD (mean age 26.3 +/- 4.4) and 19 typically developed controls (26.4 +/- 4). The results confirmed previously-reported differences between groups in brain responses to emotion and a hypo-activation in the ASD group in the right fusiform gyrus around 150 ms. However, the ASD group also presented early enhanced activity in the occipital region. These results support that impaired face processing in ASD might be sustained by atypical responses in primary visual areas. En ligne : http://dx.doi.org/10.1007/s10803-018-3787-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

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