[article] 
inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880

Titre :	Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur
Article en page(s) :	p.871-880
Langues :	Anglais (eng)
Mots-clés :	Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress
Index. décimale :	PER Périodiques
Résumé :	BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation.
En ligne :	http://dx.doi.org/10.1111/jcpp.13532
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

[article] Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation [Texte imprimé et/ou numérique] / Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur . - p.871-880.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880

Mots-clés :	Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress
Index. décimale :	PER Périodiques
Résumé :	BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation.
En ligne :	http://dx.doi.org/10.1111/jcpp.13532
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486