Eye-Hand Coordination in Children with High Functioning Autism and Asperger’s Disorder Using a Gap-Overlap Paradigm / Alessandro CRIPPA in Journal of Autism and Developmental Disorders, 43-4 (April 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-4 (April 2013) . - p.841-850 Titre : Eye-Hand Coordination in Children with High Functioning Autism and Asperger’s Disorder Using a Gap-Overlap Paradigm Type de document : Texte imprimé et/ou numérique Auteurs : Alessandro CRIPPA, Auteur ; Sara FORTI, Auteur ; Paolo PEREGO, Auteur ; Massimo MOLTENI, Auteur Article en page(s) : p.841-850 Langues : Anglais (eng) Mots-clés : Autism  Eye hand coordination  Gap effect  Oculomotor control Index. décimale : PER Périodiques Résumé : We investigated eye-hand coordination in children with autism spectrum disorders (ASD) in comparison with age-matched normally developing peers. The eye-hand correlation was measured by putting fixation latencies in relation with pointing and key pressing responses in visual detection tasks where a gap-overlap paradigm was used and compared to fixation latencies in absence of manual response. ASD patients showed less efficient eye-hand coordination, which was particularly evident when pointing towards a target was being fixated. The data of normally developing participants confirmed that manual gap effects are more likely for more complex hand movements. An important discrepancy was discovered in participants with ASD: beside normal eye gap effects, they showed no concurrent hand gap effects when pointing to targets. This result has been interpreted as a further sign of inefficient eye-hand coordination in this patient population. En ligne : http://dx.doi.org/10.1007/s10803-012-1623-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=194 [article] Eye-Hand Coordination in Children with High Functioning Autism and Asperger’s Disorder Using a Gap-Overlap Paradigm [Texte imprimé et/ou numérique] / Alessandro CRIPPA, Auteur ; Sara FORTI, Auteur ; Paolo PEREGO, Auteur ; Massimo MOLTENI, Auteur . - p.841-850. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-4 (April 2013) . - p.841-850 Mots-clés : Autism  Eye hand coordination  Gap effect  Oculomotor control Index. décimale : PER Périodiques Résumé : We investigated eye-hand coordination in children with autism spectrum disorders (ASD) in comparison with age-matched normally developing peers. The eye-hand correlation was measured by putting fixation latencies in relation with pointing and key pressing responses in visual detection tasks where a gap-overlap paradigm was used and compared to fixation latencies in absence of manual response. ASD patients showed less efficient eye-hand coordination, which was particularly evident when pointing towards a target was being fixated. The data of normally developing participants confirmed that manual gap effects are more likely for more complex hand movements. An important discrepancy was discovered in participants with ASD: beside normal eye gap effects, they showed no concurrent hand gap effects when pointing to targets. This result has been interpreted as a further sign of inefficient eye-hand coordination in this patient population. En ligne : http://dx.doi.org/10.1007/s10803-012-1623-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=194

Further Empirical Data on the Psychoeducational Profile-Revised (PEP-R): Reliability and Validation with the Vineland Adaptive Behavior Scales / Susanna VILLA in Journal of Autism and Developmental Disorders, 40-3 (March 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-3 (March 2010) . - p.334-341 Titre : Further Empirical Data on the Psychoeducational Profile-Revised (PEP-R): Reliability and Validation with the Vineland Adaptive Behavior Scales Type de document : Texte imprimé et/ou numérique Auteurs : Susanna VILLA, Auteur ; Valentina PASTORE, Auteur ; Massimo MOLTENI, Auteur ; Enrico MICHELI, Auteur ; Laura VILLA, Auteur ; Alessandro CRIPPA, Auteur Année de publication : 2010 Article en page(s) : p.334-341 Langues : Anglais (eng) Mots-clés : Autism Assessment Psychometrics-properties Psychoeducational-profile- revised-(PEP-R) Vineland-Adaptive-Behavior-Scales Index. décimale : PER Périodiques Résumé : The PEP-R (psychoeducational profile revised) is an instrument that has been used in many countries to assess abilities and formulate treatment programs for children with autism and related developmental disorders. To the end to provide further information on the PEP-R’s psychometric properties, a large sample (N = 137) of children presenting Autistic Disorder symptoms under the age of 12 years, including low-functioning individuals, was examined. Results yielded data of interest especially in terms of: Cronbach’s alpha, interrater reliability, and validation with the Vineland Adaptive Behavior Scales. These findings help complete the instrument’s statistical description and augment its usefulness, not only in designing treatment programs for these individuals, but also as an instrument for verifying the efficacy of intervention. En ligne : http://dx.doi.org/10.1007/s10803-009-0877-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=966 [article] Further Empirical Data on the Psychoeducational Profile-Revised (PEP-R): Reliability and Validation with the Vineland Adaptive Behavior Scales [Texte imprimé et/ou numérique] / Susanna VILLA, Auteur ; Valentina PASTORE, Auteur ; Massimo MOLTENI, Auteur ; Enrico MICHELI, Auteur ; Laura VILLA, Auteur ; Alessandro CRIPPA, Auteur . - 2010 . - p.334-341. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-3 (March 2010) . - p.334-341 Mots-clés : Autism Assessment Psychometrics-properties Psychoeducational-profile- revised-(PEP-R) Vineland-Adaptive-Behavior-Scales Index. décimale : PER Périodiques Résumé : The PEP-R (psychoeducational profile revised) is an instrument that has been used in many countries to assess abilities and formulate treatment programs for children with autism and related developmental disorders. To the end to provide further information on the PEP-R’s psychometric properties, a large sample (N = 137) of children presenting Autistic Disorder symptoms under the age of 12 years, including low-functioning individuals, was examined. Results yielded data of interest especially in terms of: Cronbach’s alpha, interrater reliability, and validation with the Vineland Adaptive Behavior Scales. These findings help complete the instrument’s statistical description and augment its usefulness, not only in designing treatment programs for these individuals, but also as an instrument for verifying the efficacy of intervention. En ligne : http://dx.doi.org/10.1007/s10803-009-0877-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=966

Further evidence of complex motor dysfunction in drug naïve children with autism using automatic motion analysis of gait / Maria NOBILE in Autism, 15-3 (May 2011)  

Public ISBD [article]  inAutism > 15-3 (May 2011) . - p.263-283 Titre : Further evidence of complex motor dysfunction in drug naïve children with autism using automatic motion analysis of gait Type de document : Texte imprimé et/ou numérique Auteurs : Maria NOBILE, Auteur ; Paolo PEREGO, Auteur ; Luigi PICCININI, Auteur ; Elisa MANI, Auteur ; Agnese ROSSI, Auteur ; Monica BELLINA, Auteur ; Massimo MOLTENI, Auteur Année de publication : 2011 Article en page(s) : p.263-283 Langues : Anglais (eng) Mots-clés : autism  gait analysis  jerk  locomotion system  motor dysfunction Index. décimale : PER Périodiques Résumé : In order to increase the knowledge of locomotor disturbances in children with autism, and of the mechanism underlying them, the objective of this exploratory study was to reliably and quantitatively evaluate linear gait parameters (spatio-temporal and kinematic parameters), upper body kinematic parameters, walk orientation and smoothness using an automatic motion analyser (ELITE systems) in drug naïve children with Autistic Disorder (AD) and healthy controls. The children with AD showed a stiffer gait in which the usual fluidity of walking was lost, trunk postural abnormalities, highly significant difficulties to maintain a straight line and a marked loss of smoothness (increase of jerk index), compared to the healthy controls. As a whole, these data suggest a complex motor dysfunction involving both the cortical and the subcortical area or, maybe, a possible deficit in the integration of sensory-motor information within motor networks (i.e., anomalous connections within the fronto-cerebello-thalamo-frontal network). Although the underlying neural structures involved remain to be better defined, these data may contribute to highlighting the central role of motor impairment in autism and suggest the usefulness of taking into account motor difficulties when developing new diagnostic and rehabilitation programs. En ligne : http://dx.doi.org/10.1177/1362361309356929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130 [article] Further evidence of complex motor dysfunction in drug naïve children with autism using automatic motion analysis of gait [Texte imprimé et/ou numérique] / Maria NOBILE, Auteur ; Paolo PEREGO, Auteur ; Luigi PICCININI, Auteur ; Elisa MANI, Auteur ; Agnese ROSSI, Auteur ; Monica BELLINA, Auteur ; Massimo MOLTENI, Auteur . - 2011 . - p.263-283. Langues : Anglais (eng) in Autism > 15-3 (May 2011) . - p.263-283 Mots-clés : autism  gait analysis  jerk  locomotion system  motor dysfunction Index. décimale : PER Périodiques Résumé : In order to increase the knowledge of locomotor disturbances in children with autism, and of the mechanism underlying them, the objective of this exploratory study was to reliably and quantitatively evaluate linear gait parameters (spatio-temporal and kinematic parameters), upper body kinematic parameters, walk orientation and smoothness using an automatic motion analyser (ELITE systems) in drug naïve children with Autistic Disorder (AD) and healthy controls. The children with AD showed a stiffer gait in which the usual fluidity of walking was lost, trunk postural abnormalities, highly significant difficulties to maintain a straight line and a marked loss of smoothness (increase of jerk index), compared to the healthy controls. As a whole, these data suggest a complex motor dysfunction involving both the cortical and the subcortical area or, maybe, a possible deficit in the integration of sensory-motor information within motor networks (i.e., anomalous connections within the fronto-cerebello-thalamo-frontal network). Although the underlying neural structures involved remain to be better defined, these data may contribute to highlighting the central role of motor impairment in autism and suggest the usefulness of taking into account motor difficulties when developing new diagnostic and rehabilitation programs. En ligne : http://dx.doi.org/10.1177/1362361309356929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130

Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation / Sarah NAZZARI in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880 Titre : Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation Type de document : Texte imprimé et/ou numérique Auteurs : Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur Article en page(s) : p.871-880 Langues : Anglais (eng) Mots-clés : Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation. En ligne : http://dx.doi.org/10.1111/jcpp.13532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation [Texte imprimé et/ou numérique] / Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur . - p.871-880. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880 Mots-clés : Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation. En ligne : http://dx.doi.org/10.1111/jcpp.13532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

A multimethod approach to assessing motor skills in boys and girls with autism spectrum disorder / Alessandro CRIPPA in Autism, 25-5 (July 2021)  

Public ISBD [article]  inAutism > 25-5 (July 2021) . - p.1481-1491 Titre : A multimethod approach to assessing motor skills in boys and girls with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Alessandro CRIPPA, Auteur ; Francesco CRAIG, Auteur ; Silvia BUSTI CECCARELLI, Auteur ; Maddalena MAURI, Auteur ; Silvia GRAZIOLI, Auteur ; Nicoletta SCIONTI, Auteur ; Alice CREMASCOLI, Auteur ; Camilla FERRANTE, Auteur ; Chiara VISIOLI, Auteur ; Gian Marco MARZOCCHI, Auteur ; Massimo MOLTENI, Auteur ; Maria NOBILE, Auteur Article en page(s) : p.1481-1491 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Child  Female  Humans  Male  Motor Skills  Quality of Life  Sex Factors  kinematics  motion capture  sex differences Index. décimale : PER Périodiques Résumé : Motor peculiarities are often reported in children with autism spectrum disorder and may predict subsequent adaptive functioning and quality of life. Although the sex bias in the prevalence of the disorder is well documented, little is known about differences in motor profile in males and females with autism spectrum disorder. Our goal was to study differences in motor functioning of boys and girls with autism spectrum disorder aged 3-11?years compared with typically developing children. Their motor performances were evaluated using a multimethod approach, including standardized motor tests, caregiver reports, and a detailed motion capture analysis of a simple reach-to-drop movement. We found that, irrespective of sex, children with autism spectrum disorder had worse scores than typically developing children on standardized tests and on caregiver reports. Interestingly, girls with autism spectrum disorder, but not boys, presented altered motor anticipation in reach-to-drop. Our findings emphasize the need for more sex-specific assessment of motor function in autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361321995634 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] A multimethod approach to assessing motor skills in boys and girls with autism spectrum disorder [Texte imprimé et/ou numérique] / Alessandro CRIPPA, Auteur ; Francesco CRAIG, Auteur ; Silvia BUSTI CECCARELLI, Auteur ; Maddalena MAURI, Auteur ; Silvia GRAZIOLI, Auteur ; Nicoletta SCIONTI, Auteur ; Alice CREMASCOLI, Auteur ; Camilla FERRANTE, Auteur ; Chiara VISIOLI, Auteur ; Gian Marco MARZOCCHI, Auteur ; Massimo MOLTENI, Auteur ; Maria NOBILE, Auteur . - p.1481-1491. Langues : Anglais (eng) in Autism > 25-5 (July 2021) . - p.1481-1491 Mots-clés : Autism Spectrum Disorder  Child  Female  Humans  Male  Motor Skills  Quality of Life  Sex Factors  kinematics  motion capture  sex differences Index. décimale : PER Périodiques Résumé : Motor peculiarities are often reported in children with autism spectrum disorder and may predict subsequent adaptive functioning and quality of life. Although the sex bias in the prevalence of the disorder is well documented, little is known about differences in motor profile in males and females with autism spectrum disorder. Our goal was to study differences in motor functioning of boys and girls with autism spectrum disorder aged 3-11?years compared with typically developing children. Their motor performances were evaluated using a multimethod approach, including standardized motor tests, caregiver reports, and a detailed motion capture analysis of a simple reach-to-drop movement. We found that, irrespective of sex, children with autism spectrum disorder had worse scores than typically developing children on standardized tests and on caregiver reports. Interestingly, girls with autism spectrum disorder, but not boys, presented altered motor anticipation in reach-to-drop. Our findings emphasize the need for more sex-specific assessment of motor function in autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361321995634 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

A multimethod approach to assessing motor skills in boys and girls with autism spectrum disorder / Alessandro CRIPPA in Autism, 26-5 (July 2022)  

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A multimodal approach can identify specific motor profiles in autism and attention-deficit/hyperactivity disorder / Stefano DE FRANCESCO in Autism Research, 16-8 (August 2023)  

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Navigation and exploration of an urban virtual environment by children with autism spectrum disorder compared to children with typical development / Livia FORNASARI in Research in Autism Spectrum Disorders, 7-8 (August 2013)  

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Social skill training in autism spectrum disorders / Massimo MOLTENI

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Socioeconomic status mediates the genetic contribution of the dopamine receptor D4 and serotonin transporter linked promoter region repeat polymorphisms to externalization in preadolescence / Maria NOBILE in Development and Psychopathology, 19-4 (Fall 2007)  

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The influence of family structure, the TPH2 G-703T and the 5-HTTLPR serotonergic genes upon affective problems in children aged 10–14 years / Maria NOBILE in Journal of Child Psychology and Psychiatry, 50-3 (March 2009)  

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Three-Dimensional Kinematic Analysis of Prehension Movements in Young Children with Autism Spectrum Disorder: New Insights on Motor Impairment / Giovanna Cristina CAMPIONE in Journal of Autism and Developmental Disorders, 46-6 (June 2016)  

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Understanding feeding problems in autistic children: Exploring the interplay between internalizing symptoms and sensory features / Alessandro CRIPPA in Autism, 26-8 (November 2022)  

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Use of Machine Learning to Identify Children with Autism and Their Motor Abnormalities / Alessandro CRIPPA in Journal of Autism and Developmental Disorders, 45-7 (July 2015)  

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