Autism severity aggregates with family psychiatric history in a community-based autism sample / D. SIPSOCK in Autism Research, 14-12 (December 2021)  

Public ISBD [article]  inAutism Research > 14-12 (December 2021) . - p.2524-2532 Titre : Autism severity aggregates with family psychiatric history in a community-based autism sample Type de document : Texte imprimé et/ou numérique Auteurs : D. SIPSOCK, Auteur ; H. TOKADJIAN, Auteur ; G. RIGHI, Auteur ; E. M. MORROW, Auteur ; S. J. SHEINKOPF, Auteur Article en page(s) : p.2524-2532 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/complications/genetics  Autistic Disorder/genetics  Family  Humans  Longitudinal Studies  Registries  autism spectrum disorder  disease severity  family medical history  population study  registry Index. décimale : PER Périodiques Résumé : The purpose of this study was to examine family psychiatric history in individuals with autism spectrum disorder (ASD) and its association with clinical presentation. Participants were 798 individuals with a clinical diagnosis of ASD, confirmed by the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), enrolled in Rhode Island Consortium for Autism Research and Treatment, a statewide research registry. Prior research suggests a specific behavioral phenotype in individuals with ASD who have family members with psychiatric diagnoses, including higher IQ and less severe language impairment. However, studies have not specifically investigated autism severity. We hypothesized that increased psychiatric family history would be associated with increased autism severity symptoms. Results show a strong association of increased burden of first-degree family psychiatric history with higher autism symptom severity as measured by Social Responsiveness Scale, Second Edition (SRS-2), but not with ADOS-2 severity scores, IQ, or adaptive functioning. These findings support the importance of investigating the contribution of psychiatric family history toward clinical ASD presentation. LAY SUMMARY: This study explored how family psychiatric history is related to clinical presentation of Autism Spectrum Disorder (ASD). Higher amounts of first-degree family psychiatric history was associated with higher autism symptom severity as measured by the Social Responsiveness Scale, Second Edition (SRS-2). The contribution of psychiatric family history requires ongoing investigation. En ligne : http://dx.doi.org/10.1002/aur.2625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Autism severity aggregates with family psychiatric history in a community-based autism sample [Texte imprimé et/ou numérique] / D. SIPSOCK, Auteur ; H. TOKADJIAN, Auteur ; G. RIGHI, Auteur ; E. M. MORROW, Auteur ; S. J. SHEINKOPF, Auteur . - p.2524-2532. Langues : Anglais (eng) in Autism Research > 14-12 (December 2021) . - p.2524-2532 Mots-clés : Autism Spectrum Disorder/complications/genetics  Autistic Disorder/genetics  Family  Humans  Longitudinal Studies  Registries  autism spectrum disorder  disease severity  family medical history  population study  registry Index. décimale : PER Périodiques Résumé : The purpose of this study was to examine family psychiatric history in individuals with autism spectrum disorder (ASD) and its association with clinical presentation. Participants were 798 individuals with a clinical diagnosis of ASD, confirmed by the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), enrolled in Rhode Island Consortium for Autism Research and Treatment, a statewide research registry. Prior research suggests a specific behavioral phenotype in individuals with ASD who have family members with psychiatric diagnoses, including higher IQ and less severe language impairment. However, studies have not specifically investigated autism severity. We hypothesized that increased psychiatric family history would be associated with increased autism severity symptoms. Results show a strong association of increased burden of first-degree family psychiatric history with higher autism symptom severity as measured by Social Responsiveness Scale, Second Edition (SRS-2), but not with ADOS-2 severity scores, IQ, or adaptive functioning. These findings support the importance of investigating the contribution of psychiatric family history toward clinical ASD presentation. LAY SUMMARY: This study explored how family psychiatric history is related to clinical presentation of Autism Spectrum Disorder (ASD). Higher amounts of first-degree family psychiatric history was associated with higher autism symptom severity as measured by the Social Responsiveness Scale, Second Edition (SRS-2). The contribution of psychiatric family history requires ongoing investigation. En ligne : http://dx.doi.org/10.1002/aur.2625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison / K. A. PEDERSEN in Journal of Autism and Developmental Disorders, 48-11 (November 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3658-3667 Titre : Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison Type de document : Texte imprimé et/ou numérique Auteurs : K. A. PEDERSEN, Auteur ; Susan L. SANTANGELO, Auteur ; R. L. GABRIELS, Auteur ; G. RIGHI, Auteur ; M. ERARD, Auteur ; M. SIEGEL, Auteur Article en page(s) : p.3658-3667 Langues : Anglais (eng) Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder (ASD)  Crisis  Externalizing problem behaviors  Psychiatric inpatients  Self-injurious behavior  Tantrum-like behavior Index. décimale : PER Périodiques Résumé : Psychiatric hospitalization of children with autism spectrum disorder (ASD) is relatively common and occurs at a higher rate than in non-ASD youth. This study compared changes in the severity of serious problem behaviors in 350 youth with ASD enrolled in the autism inpatient collection during and after hospitalization in six specialized child psychiatry units. There was a significant reduction in serious problem behaviors from admission (aberrant behavior checklist-irritability subscale M = 29.7, SD 9.6) to discharge (M = 15.0, SD 10.3) and 2-month follow-up (M = 19.3, SD 10.3). Between discharge and 2-month follow-up, tantrum-like behaviors but not self-injurious behaviors increased slightly. Improvement in the severity of problem behaviors was not uniform across sites, even after controlling for measured site differences. En ligne : http://dx.doi.org/10.1007/s10803-017-3366-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison [Texte imprimé et/ou numérique] / K. A. PEDERSEN, Auteur ; Susan L. SANTANGELO, Auteur ; R. L. GABRIELS, Auteur ; G. RIGHI, Auteur ; M. ERARD, Auteur ; M. SIEGEL, Auteur . - p.3658-3667. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3658-3667 Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder (ASD)  Crisis  Externalizing problem behaviors  Psychiatric inpatients  Self-injurious behavior  Tantrum-like behavior Index. décimale : PER Périodiques Résumé : Psychiatric hospitalization of children with autism spectrum disorder (ASD) is relatively common and occurs at a higher rate than in non-ASD youth. This study compared changes in the severity of serious problem behaviors in 350 youth with ASD enrolled in the autism inpatient collection during and after hospitalization in six specialized child psychiatry units. There was a significant reduction in serious problem behaviors from admission (aberrant behavior checklist-irritability subscale M = 29.7, SD 9.6) to discharge (M = 15.0, SD 10.3) and 2-month follow-up (M = 19.3, SD 10.3). Between discharge and 2-month follow-up, tantrum-like behaviors but not self-injurious behaviors increased slightly. Improvement in the severity of problem behaviors was not uniform across sites, even after controlling for measured site differences. En ligne : http://dx.doi.org/10.1007/s10803-017-3366-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder / G. RIGHI in Journal of Autism and Developmental Disorders, 48-11 (November 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3647-3657 Titre : Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : G. RIGHI, Auteur ; J. BENEVIDES, Auteur ; C. MAZEFSKY, Auteur ; M. SIEGEL, Auteur ; S. J. SHEINKOPF, Auteur ; E. M. MORROW, Auteur Article en page(s) : p.3647-3657 Langues : Anglais (eng) Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder  Children and adolescents  Inpatient psychiatric hospitalization Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is associated with significant healthcare expenditures and a greater utilization of psychiatric health services. High utilization may not be evenly distributed across individuals with ASD. The objective of this study was to identify individual and family characteristics that increase the risk of psychiatric hospitalization. Naturalistic study of two age- and gender-matched ASD cohorts, inpatients enrolled in the Autism Inpatient Collection (AIC) and outpatients enrolled in the Rhode Island Consortium of Autism Research and Treatment (RI-CART), revealed a number of factors associated with hospitalization. Multiple logistic regression analyses revealed that adaptive functioning, ASD symptom severity, primary caregiver's marital status, the presence of mood disorders, and the presence of sleep problems independently increased the risk of psychiatric hospitalization. En ligne : http://dx.doi.org/10.1007/s10803-017-3154-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / G. RIGHI, Auteur ; J. BENEVIDES, Auteur ; C. MAZEFSKY, Auteur ; M. SIEGEL, Auteur ; S. J. SHEINKOPF, Auteur ; E. M. MORROW, Auteur . - p.3647-3657. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3647-3657 Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder  Children and adolescents  Inpatient psychiatric hospitalization Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is associated with significant healthcare expenditures and a greater utilization of psychiatric health services. High utilization may not be evenly distributed across individuals with ASD. The objective of this study was to identify individual and family characteristics that increase the risk of psychiatric hospitalization. Naturalistic study of two age- and gender-matched ASD cohorts, inpatients enrolled in the Autism Inpatient Collection (AIC) and outpatients enrolled in the Rhode Island Consortium of Autism Research and Treatment (RI-CART), revealed a number of factors associated with hospitalization. Multiple logistic regression analyses revealed that adaptive functioning, ASD symptom severity, primary caregiver's marital status, the presence of mood disorders, and the presence of sleep problems independently increased the risk of psychiatric hospitalization. En ligne : http://dx.doi.org/10.1007/s10803-017-3154-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

Sensitivity to audio-visual synchrony and its relation to language abilities in children with and without ASD / G. RIGHI in Autism Research, 11-4 (April 2018)  

Public ISBD [article]  inAutism Research > 11-4 (April 2018) . - p.645-653 Titre : Sensitivity to audio-visual synchrony and its relation to language abilities in children with and without ASD Type de document : Texte imprimé et/ou numérique Auteurs : G. RIGHI, Auteur ; E. J. TENENBAUM, Auteur ; C. MCCORMICK, Auteur ; M. BLOSSOM, Auteur ; Dima AMSO, Auteur ; S. J. SHEINKOPF, Auteur Article en page(s) : p.645-653 Langues : Anglais (eng) Mots-clés : audio-visual synchrony  autism  eye-tracking  language development Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is often accompanied by deficits in speech and language processing. Speech processing relies heavily on the integration of auditory and visual information, and it has been suggested that the ability to detect correspondence between auditory and visual signals helps to lay the foundation for successful language development. The goal of the present study was to examine whether young children with ASD show reduced sensitivity to temporal asynchronies in a speech processing task when compared to typically developing controls, and to examine how this sensitivity might relate to language proficiency. Using automated eye tracking methods, we found that children with ASD failed to demonstrate sensitivity to asynchronies of 0.3s, 0.6s, or 1.0s between a video of a woman speaking and the corresponding audio track. In contrast, typically developing children who were language-matched to the ASD group, were sensitive to both 0.6s and 1.0s asynchronies. We also demonstrated that individual differences in sensitivity to audiovisual asynchronies and individual differences in orientation to relevant facial features were both correlated with scores on a standardized measure of language abilities. Results are discussed in the context of attention to visual language and audio-visual processing as potential precursors to language impairment in ASD. Autism Res 2018, 11: 645-653. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Speech processing relies heavily on the integration of auditory and visual information, and it has been suggested that the ability to detect correspondence between auditory and visual signals helps to lay the foundation for successful language development. The goal of the present study was to explore whether children with ASD process audio-visual synchrony in ways comparable to their typically developing peers, and the relationship between preference for synchrony and language ability. Results showed that there are differences in attention to audiovisual synchrony between typically developing children and children with ASD. Preference for synchrony was related to the language abilities of children across groups. En ligne : http://dx.doi.org/10.1002/aur.1918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358 [article] Sensitivity to audio-visual synchrony and its relation to language abilities in children with and without ASD [Texte imprimé et/ou numérique] / G. RIGHI, Auteur ; E. J. TENENBAUM, Auteur ; C. MCCORMICK, Auteur ; M. BLOSSOM, Auteur ; Dima AMSO, Auteur ; S. J. SHEINKOPF, Auteur . - p.645-653. Langues : Anglais (eng) in Autism Research > 11-4 (April 2018) . - p.645-653 Mots-clés : audio-visual synchrony  autism  eye-tracking  language development Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is often accompanied by deficits in speech and language processing. Speech processing relies heavily on the integration of auditory and visual information, and it has been suggested that the ability to detect correspondence between auditory and visual signals helps to lay the foundation for successful language development. The goal of the present study was to examine whether young children with ASD show reduced sensitivity to temporal asynchronies in a speech processing task when compared to typically developing controls, and to examine how this sensitivity might relate to language proficiency. Using automated eye tracking methods, we found that children with ASD failed to demonstrate sensitivity to asynchronies of 0.3s, 0.6s, or 1.0s between a video of a woman speaking and the corresponding audio track. In contrast, typically developing children who were language-matched to the ASD group, were sensitive to both 0.6s and 1.0s asynchronies. We also demonstrated that individual differences in sensitivity to audiovisual asynchronies and individual differences in orientation to relevant facial features were both correlated with scores on a standardized measure of language abilities. Results are discussed in the context of attention to visual language and audio-visual processing as potential precursors to language impairment in ASD. Autism Res 2018, 11: 645-653. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Speech processing relies heavily on the integration of auditory and visual information, and it has been suggested that the ability to detect correspondence between auditory and visual signals helps to lay the foundation for successful language development. The goal of the present study was to explore whether children with ASD process audio-visual synchrony in ways comparable to their typically developing peers, and the relationship between preference for synchrony and language ability. Results showed that there are differences in attention to audiovisual synchrony between typically developing children and children with ASD. Preference for synchrony was related to the language abilities of children across groups. En ligne : http://dx.doi.org/10.1002/aur.1918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358

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