ADHD medication adherence reduces risk of committing minor offenses in adolescents / Paul T. ROSENAU in Journal of Child Psychology and Psychiatry, 65-11 (November 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-11 (November 2024) . - p.1478-1485 Titre : ADHD medication adherence reduces risk of committing minor offenses in adolescents Type de document : texte imprimé Auteurs : Paul T. ROSENAU, Auteur ; Andrea DIETRICH, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur Article en page(s) : p.1478-1485 Langues : Anglais (eng) Mots-clés : Adolescents  ADHD medication  risk reduction  crime  survival analysis Index. décimale : PER Périodiques Résumé : Background This study aimed to investigate the association between adolescents? adherence to attention-deficit/hyperactivity disorder (ADHD) medication and their risk of committing minor offenses. Methods Using two Dutch databases, Statistics Netherlands (CBS) and the Foundation for Pharmaceutical Statistics (SFK), we aimed to investigate the association between adherence to ADHD medication and registered minor offenses between 2005 and 2019 of 18,234 adolescents (12 18 years). We used Cox regression analyses to compare the rate of committing minor offenses of adolescents during periods of high ADHD medication adherence compared to periods of low adherence (i.e., periods with or without sufficient amounts of dispensed medication). We additionally tested associations with adherence to selective serotonin reuptake inhibitors (SSRIs) as control medication and analyzed potential reverse causation. Results High ADHD medication adherence was associated with a reduced risk of committing a minor offense of between 33% and 38% compared to low adherence periods of 3 months (hazard ratio [HR] 0.67, confidence interval [CI] 0.64 0.71) or 6 months (HR 0.62, CI 0.59 0.65). The reduction in risk can likely be attributed to ADHD medication, given the absence of effects of SSRIs and no reverse causation. The reduction rate remained between 16% and 55% per sex, stimulant versus non-stimulant medication, different offense categories and further sensitivity analyses. Conclusions Among adolescents using ADHD medication, rates of criminality were lower during periods of high medication adherence, suggesting that adherence to ADHD medication may contribute to prevention of minor offenses in adolescents. En ligne : https://doi.org/10.1111/jcpp.13997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=537 [article] ADHD medication adherence reduces risk of committing minor offenses in adolescents [texte imprimé] / Paul T. ROSENAU, Auteur ; Andrea DIETRICH, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur . - p.1478-1485. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-11 (November 2024) . - p.1478-1485 Mots-clés : Adolescents  ADHD medication  risk reduction  crime  survival analysis Index. décimale : PER Périodiques Résumé : Background This study aimed to investigate the association between adolescents? adherence to attention-deficit/hyperactivity disorder (ADHD) medication and their risk of committing minor offenses. Methods Using two Dutch databases, Statistics Netherlands (CBS) and the Foundation for Pharmaceutical Statistics (SFK), we aimed to investigate the association between adherence to ADHD medication and registered minor offenses between 2005 and 2019 of 18,234 adolescents (12 18 years). We used Cox regression analyses to compare the rate of committing minor offenses of adolescents during periods of high ADHD medication adherence compared to periods of low adherence (i.e., periods with or without sufficient amounts of dispensed medication). We additionally tested associations with adherence to selective serotonin reuptake inhibitors (SSRIs) as control medication and analyzed potential reverse causation. Results High ADHD medication adherence was associated with a reduced risk of committing a minor offense of between 33% and 38% compared to low adherence periods of 3 months (hazard ratio [HR] 0.67, confidence interval [CI] 0.64 0.71) or 6 months (HR 0.62, CI 0.59 0.65). The reduction in risk can likely be attributed to ADHD medication, given the absence of effects of SSRIs and no reverse causation. The reduction rate remained between 16% and 55% per sex, stimulant versus non-stimulant medication, different offense categories and further sensitivity analyses. Conclusions Among adolescents using ADHD medication, rates of criminality were lower during periods of high medication adherence, suggesting that adherence to ADHD medication may contribute to prevention of minor offenses in adolescents. En ligne : https://doi.org/10.1111/jcpp.13997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=537

Commentary: Why treatment is the best choice for childhood mental disorders - a commentary on Roest et al. (2022) / Tycho J. DEKKERS in Journal of Child Psychology and Psychiatry, 64-3 (March 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-3 (March 2023) . - p.470-473 Titre : Commentary: Why treatment is the best choice for childhood mental disorders - a commentary on Roest et al. (2022) Type de document : texte imprimé Auteurs : Tycho J. DEKKERS, Auteur ; Annabeth P. GROENMAN, Auteur ; Pim CUIJPERS, Auteur ; Pieter J. HOEKSTRA, Auteur ; Marjolein LUMAN, Auteur ; Bram OROBIO DE CASTRO, Auteur ; Geertjan OVERBEEK, Auteur ; Arne POPMA, Auteur ; Nanda N. ROMMELSE, Auteur ; Elske SALEMINK, Auteur ; Yvonne A.J. STIKKELBROEK, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Saskia VAN DER OORD, Auteur ; Patty LEIJTEN, Auteur Article en page(s) : p.470-473 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : An important question in mental healthcare for children is whether treatments are effective and safe in the long run. Here, we comment on a recent editorial perspective by Roest et al. (2022), who argue, based on an overview of systematic reviews, ˜that there is no convincing evidence that interventions for the most common childhood disorders are beneficial in the long term’. We believe that the available evidence does not justify this conclusion and express our concern regarding the harmful effects of their message. We show that there is evidence to suggest beneficial longer term treatment effects for each of the disorders and explain why evidence-based treatment should be offered to children with mental disorders. En ligne : https://doi.org/10.1111/jcpp.13715 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493 [article] Commentary: Why treatment is the best choice for childhood mental disorders - a commentary on Roest et al. (2022) [texte imprimé] / Tycho J. DEKKERS, Auteur ; Annabeth P. GROENMAN, Auteur ; Pim CUIJPERS, Auteur ; Pieter J. HOEKSTRA, Auteur ; Marjolein LUMAN, Auteur ; Bram OROBIO DE CASTRO, Auteur ; Geertjan OVERBEEK, Auteur ; Arne POPMA, Auteur ; Nanda N. ROMMELSE, Auteur ; Elske SALEMINK, Auteur ; Yvonne A.J. STIKKELBROEK, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Saskia VAN DER OORD, Auteur ; Patty LEIJTEN, Auteur . - p.470-473. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-3 (March 2023) . - p.470-473 Index. décimale : PER Périodiques Résumé : An important question in mental healthcare for children is whether treatments are effective and safe in the long run. Here, we comment on a recent editorial perspective by Roest et al. (2022), who argue, based on an overview of systematic reviews, ˜that there is no convincing evidence that interventions for the most common childhood disorders are beneficial in the long term’. We believe that the available evidence does not justify this conclusion and express our concern regarding the harmful effects of their message. We show that there is evidence to suggest beneficial longer term treatment effects for each of the disorders and explain why evidence-based treatment should be offered to children with mental disorders. En ligne : https://doi.org/10.1111/jcpp.13715 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493

Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children / Simone BREIDER in Journal of Autism and Developmental Disorders, 52-6 (June 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2747-2761 Titre : Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children Type de document : texte imprimé Auteurs : Simone BREIDER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Klaas J. WARDENAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Andrea DIETRICH, Auteur ; Annelies A. DE BILDT, Auteur Article en page(s) : p.2747-2761 Langues : Anglais (eng) Mots-clés : Alspac  Autism spectrum disorder  Disruptive behaviors  Early-life  Environmental  Risk factors Index. décimale : PER Périodiques Résumé : We studied the association of early-life environmental and child factors with disruptive behaviors in children with autistic traits around age 7, in the Avon Longitudinal Study of Parents and Children (n=6,401). Logistic regression with the least absolute shrinkage and selection operator indicated that disruptive behaviors were associated with prenatal smoking, no seafood-consumption during pregnancy, breech presentation at delivery, neonatal feeding problems, low social-economic situation, suboptimal preschool family environment, maternal depression, maternal antisocial behavior, male sex, and difficult child temperament. Compared to controls, male sex, maternal depression, and suboptimal preschool family environment were related to autistic traits without disruptive behaviors. Thus, there may be a difference in early-life factors related to autism spectrum disorder with and without disruptive behaviors. En ligne : http://dx.doi.org/10.1007/s10803-021-05081-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children [texte imprimé] / Simone BREIDER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Klaas J. WARDENAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Andrea DIETRICH, Auteur ; Annelies A. DE BILDT, Auteur . - p.2747-2761. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2747-2761 Mots-clés : Alspac  Autism spectrum disorder  Disruptive behaviors  Early-life  Environmental  Risk factors Index. décimale : PER Périodiques Résumé : We studied the association of early-life environmental and child factors with disruptive behaviors in children with autistic traits around age 7, in the Avon Longitudinal Study of Parents and Children (n=6,401). Logistic regression with the least absolute shrinkage and selection operator indicated that disruptive behaviors were associated with prenatal smoking, no seafood-consumption during pregnancy, breech presentation at delivery, neonatal feeding problems, low social-economic situation, suboptimal preschool family environment, maternal depression, maternal antisocial behavior, male sex, and difficult child temperament. Compared to controls, male sex, maternal depression, and suboptimal preschool family environment were related to autistic traits without disruptive behaviors. Thus, there may be a difference in early-life factors related to autism spectrum disorder with and without disruptive behaviors. En ligne : http://dx.doi.org/10.1007/s10803-021-05081-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Effects of methylphenidate on executive functioning in children and adolescents with ADHD after long-term use: a randomized, placebo-controlled discontinuation study / Paul T. ROSENAU in Journal of Child Psychology and Psychiatry, 62-12 (December 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-12 (December 2021) . - p.1444-1452 Titre : Effects of methylphenidate on executive functioning in children and adolescents with ADHD after long-term use: a randomized, placebo-controlled discontinuation study Type de document : texte imprimé Auteurs : Paul T. ROSENAU, Auteur ; Thaïra J.C. OPENNEER, Auteur ; Anne-Flore M. MATTHIJSSEN, Auteur ; Gigi H.H. VAN DE LOO-NEUS, Auteur ; Jan K. BUITELAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Andrea DIETRICH, Auteur Article en page(s) : p.1444-1452 Langues : Anglais (eng) Mots-clés : Adolescent  Attention Deficit Disorder with Hyperactivity/drug therapy  Central Nervous System Stimulants/adverse effects  Child  Double-Blind Method  Executive Function  Humans  Methylphenidate/adverse effects  Netherlands  Treatment Outcome  attention-deficit/hyperactivity disorder  executive functioning  long-term  methylphenidate  working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Methylphenidate may improve executive functioning in children with attention-deficit/hyperactivity disorder (ADHD). However, it is unclear if there are still acute effects of methylphenidate on executive functioning after long-term use. METHODS: In a randomized double-blind, placebo-controlled discontinuation study, 94 children and adolescents (ages 8-18 years) who used methylphenidate beyond two years were either assigned to seven weeks of continued treatment with 36 or 54 mg of extended-release methylphenidate or to gradual withdrawal over three weeks to placebo for four weeks. Performance on neuropsychological tasks, measuring working memory, response inhibition, attentional flexibility and psychomotor speed was compared between both groups using mixed models for repeated measures. Additionally, we investigated within the discontinuation group if a deterioration on the investigator-rated Clinical Global Impressions Improvement scale after withdrawing to placebo was related to a worse performance on the neuropsychological tasks. This study was registered in the Netherlands Trial Register (www. Trialregister.nl) with identifier 5252. RESULTS: After withdrawal of methylphenidate, the discontinuation group made more errors on working memory (β = -1.62, SD = 0.56, t = -2.88, p = .01, Cohen's f2 = .14), independent from reaction time compared to baseline, in contrast to the continuation group. We did not find differences in changes in response inhibition, attentional flexibility and psychomotor speed between the two groups. Also, there were no significant differences in task measures between the participants who deteriorated clinically and those who did not. CONCLUSIONS: Our study shows that methylphenidate has a beneficial effect on working memory after two years of use. Future studies should explore whether cognitive outcomes may aid clinical decision-making on the continued use of methylphenidate, given dissociation between cognitive and behavioural effects of stimulant medication. En ligne : http://dx.doi.org/10.1111/jcpp.13419 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Effects of methylphenidate on executive functioning in children and adolescents with ADHD after long-term use: a randomized, placebo-controlled discontinuation study [texte imprimé] / Paul T. ROSENAU, Auteur ; Thaïra J.C. OPENNEER, Auteur ; Anne-Flore M. MATTHIJSSEN, Auteur ; Gigi H.H. VAN DE LOO-NEUS, Auteur ; Jan K. BUITELAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Andrea DIETRICH, Auteur . - p.1444-1452. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-12 (December 2021) . - p.1444-1452 Mots-clés : Adolescent  Attention Deficit Disorder with Hyperactivity/drug therapy  Central Nervous System Stimulants/adverse effects  Child  Double-Blind Method  Executive Function  Humans  Methylphenidate/adverse effects  Netherlands  Treatment Outcome  attention-deficit/hyperactivity disorder  executive functioning  long-term  methylphenidate  working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Methylphenidate may improve executive functioning in children with attention-deficit/hyperactivity disorder (ADHD). However, it is unclear if there are still acute effects of methylphenidate on executive functioning after long-term use. METHODS: In a randomized double-blind, placebo-controlled discontinuation study, 94 children and adolescents (ages 8-18 years) who used methylphenidate beyond two years were either assigned to seven weeks of continued treatment with 36 or 54 mg of extended-release methylphenidate or to gradual withdrawal over three weeks to placebo for four weeks. Performance on neuropsychological tasks, measuring working memory, response inhibition, attentional flexibility and psychomotor speed was compared between both groups using mixed models for repeated measures. Additionally, we investigated within the discontinuation group if a deterioration on the investigator-rated Clinical Global Impressions Improvement scale after withdrawing to placebo was related to a worse performance on the neuropsychological tasks. This study was registered in the Netherlands Trial Register (www. Trialregister.nl) with identifier 5252. RESULTS: After withdrawal of methylphenidate, the discontinuation group made more errors on working memory (β = -1.62, SD = 0.56, t = -2.88, p = .01, Cohen's f2 = .14), independent from reaction time compared to baseline, in contrast to the continuation group. We did not find differences in changes in response inhibition, attentional flexibility and psychomotor speed between the two groups. Also, there were no significant differences in task measures between the participants who deteriorated clinically and those who did not. CONCLUSIONS: Our study shows that methylphenidate has a beneficial effect on working memory after two years of use. Future studies should explore whether cognitive outcomes may aid clinical decision-making on the continued use of methylphenidate, given dissociation between cognitive and behavioural effects of stimulant medication. En ligne : http://dx.doi.org/10.1111/jcpp.13419 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Have parenting programs for disruptive child behavior become less effective? / Patty LEIJTEN in Journal of Child Psychology and Psychiatry, 67-1 (January 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-1 (January 2026) . - p.127-137 Titre : Have parenting programs for disruptive child behavior become less effective? Type de document : texte imprimé Auteurs : Patty LEIJTEN, Auteur ; G.J. MELENDEZ-TORRES, Auteur ; Sophia BACKHAUS, Auteur ; Frances GARDNER, Auteur ; Annabeth P. GROENMAN, Auteur ; Tycho J. DEKKERS, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Liina Björg LAAS SIGURÐARDÓTTIR, Auteur ; Danni LIU, Auteur ; Marjolein LUMAN, Auteur ; Lara MANSUR, Auteur ; Merlin NIETERAU, Auteur ; Saskia VAN DER OORD, Auteur ; Geertjan OVERBEEK, Auteur ; Constantina PSYLLOU, Auteur ; Karen RIENKS, Auteur ; Susanne SCHULZ, Auteur ; John R. WEISZ, Auteur Article en page(s) : p.127-137 Langues : Anglais (eng) Mots-clés : Behavioral parenting program  disruptive child behavior  systematic review  meta-analysis  time trends Index. décimale : PER Périodiques Résumé : Background Behavioral parenting programs have been exhaustively studied over the past five decades. We used this wealth of research to examine how estimates of parenting program effects have evolved over time, and if any time trends in effect estimates can be explained by trial, sample, or intervention characteristics. Methods We based our meta-analysis on a systematic search of 22 international and regional databases, gray literature, and 4 trial registries for randomized controlled trials of behavioral parenting programs. Results We identified 244 eligible trials (1,100 effect sizes; 28,916 families) from 36 countries. Parenting program effects initially reduced and then stabilized. More recent trials used more rigorous methods (e.g., more active control conditions and less risk of bias), samples that were generally older and included more girls, and evaluated interventions that on average had fewer sessions, were more often delivered by independent staff and made less use of time-out. However, none of these developments explained the initial reduction in effect size estimates during the first decades. Conclusions Our findings suggest that estimates of parenting program effects are currently stable: Effect sizes are no longer reducing but there is also no evidence of increases over time. Experimentation with the content, delivery, and personalization of parenting programs is needed to identify ways to increase program effects. En ligne : https://doi.org/10.1111/jcpp.70049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578 [article] Have parenting programs for disruptive child behavior become less effective? [texte imprimé] / Patty LEIJTEN, Auteur ; G.J. MELENDEZ-TORRES, Auteur ; Sophia BACKHAUS, Auteur ; Frances GARDNER, Auteur ; Annabeth P. GROENMAN, Auteur ; Tycho J. DEKKERS, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Liina Björg LAAS SIGURÐARDÓTTIR, Auteur ; Danni LIU, Auteur ; Marjolein LUMAN, Auteur ; Lara MANSUR, Auteur ; Merlin NIETERAU, Auteur ; Saskia VAN DER OORD, Auteur ; Geertjan OVERBEEK, Auteur ; Constantina PSYLLOU, Auteur ; Karen RIENKS, Auteur ; Susanne SCHULZ, Auteur ; John R. WEISZ, Auteur . - p.127-137. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-1 (January 2026) . - p.127-137 Mots-clés : Behavioral parenting program  disruptive child behavior  systematic review  meta-analysis  time trends Index. décimale : PER Périodiques Résumé : Background Behavioral parenting programs have been exhaustively studied over the past five decades. We used this wealth of research to examine how estimates of parenting program effects have evolved over time, and if any time trends in effect estimates can be explained by trial, sample, or intervention characteristics. Methods We based our meta-analysis on a systematic search of 22 international and regional databases, gray literature, and 4 trial registries for randomized controlled trials of behavioral parenting programs. Results We identified 244 eligible trials (1,100 effect sizes; 28,916 families) from 36 countries. Parenting program effects initially reduced and then stabilized. More recent trials used more rigorous methods (e.g., more active control conditions and less risk of bias), samples that were generally older and included more girls, and evaluated interventions that on average had fewer sessions, were more often delivered by independent staff and made less use of time-out. However, none of these developments explained the initial reduction in effect size estimates during the first decades. Conclusions Our findings suggest that estimates of parenting program effects are currently stable: Effect sizes are no longer reducing but there is also no evidence of increases over time. Experimentation with the content, delivery, and personalization of parenting programs is needed to identify ways to increase program effects. En ligne : https://doi.org/10.1111/jcpp.70049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578

Practitioner Review: Current best practice in the use of parent training and other behavioural interventions in the treatment of children and adolescents with attention deficit hyperactivity disorder / David DALEY in Journal of Child Psychology and Psychiatry, 59-9 (September 2018)  

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Research Review: Mechanisms of change and between-family differences in parenting interventions for children with ADHD - an individual participant data meta-analysis / Constantina PSYLLOU in Journal of Child Psychology and Psychiatry, 66-9 (September 2025)  

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Treatments with versus without medication for children with behavioural difficulties in clinical practice: an economic evaluation with observational data / Hermien H. DIJK ; Barbara J. VAN DEN HOOFDAKKER ; Pieter J. HOEKSTRA ; Annabeth P. GROENMAN in Journal of Child Psychology and Psychiatry, 66-3 (March 2025)  

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