Developing a neurobehavioral animal model of poverty: Drawing cross-species connections between environments of scarcity-adversity, parenting quality, and infant outcome / Rosemarie E. PERRY in Development and Psychopathology, 31-2 (May 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-2 (May 2019) . - p.399-418 Titre : Developing a neurobehavioral animal model of poverty: Drawing cross-species connections between environments of scarcity-adversity, parenting quality, and infant outcome Type de document : Texte imprimé et/ou numérique Auteurs : Rosemarie E. PERRY, Auteur ; Eric D. FINEGOOD, Auteur ; Stephen H. BRAREN, Auteur ; Meriah L. DEJOSEPH, Auteur ; David F. PUTRINO, Auteur ; Donald A. WILSON, Auteur ; Regina M. SULLIVAN, Auteur ; C. Cybele RAVER, Auteur ; Clancy BLAIR, Auteur Article en page(s) : p.399-418 Langues : Anglais (eng) Mots-clés : brain development parenting poverty regulation Index. décimale : PER Périodiques Résumé : Children reared in impoverished environments are at risk for enduring psychological and physical health problems. Mechanisms by which poverty affects development, however, remain unclear. To explore one potential mechanism of poverty's impact on social–emotional and cognitive development, an experimental examination of a rodent model of scarcity-adversity was conducted and compared to results from a longitudinal study of human infants and families followed from birth (N = 1,292) who faced high levels of poverty-related scarcity-adversity. Cross-species results supported the hypothesis that altered caregiving is one pathway by which poverty adversely impacts development. Rodent mothers assigned to the scarcity-adversity condition exhibited decreased sensitive parenting and increased negative parenting relative to mothers assigned to the control condition. Furthermore, scarcity-adversity reared pups exhibited decreased developmental competence as indicated by disrupted nipple attachment, distress vocalization when in physical contact with an anesthetized mother, and reduced preference for maternal odor with corresponding changes in brain activation. Human results indicated that scarcity-adversity was inversely correlated with sensitive parenting and positively correlated with negative parenting, and that parenting fully mediated the association of poverty-related risk with infant indicators of developmental competence. Findings are discussed from the perspective of the usefulness of bidirectional–translational research to inform interventions for at-risk families. En ligne : http://dx.doi.org/10.1017/S095457941800007X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393 [article] Developing a neurobehavioral animal model of poverty: Drawing cross-species connections between environments of scarcity-adversity, parenting quality, and infant outcome [Texte imprimé et/ou numérique] / Rosemarie E. PERRY, Auteur ; Eric D. FINEGOOD, Auteur ; Stephen H. BRAREN, Auteur ; Meriah L. DEJOSEPH, Auteur ; David F. PUTRINO, Auteur ; Donald A. WILSON, Auteur ; Regina M. SULLIVAN, Auteur ; C. Cybele RAVER, Auteur ; Clancy BLAIR, Auteur . - p.399-418. Langues : Anglais (eng) in Development and Psychopathology > 31-2 (May 2019) . - p.399-418 Mots-clés : brain development parenting poverty regulation Index. décimale : PER Périodiques Résumé : Children reared in impoverished environments are at risk for enduring psychological and physical health problems. Mechanisms by which poverty affects development, however, remain unclear. To explore one potential mechanism of poverty's impact on social–emotional and cognitive development, an experimental examination of a rodent model of scarcity-adversity was conducted and compared to results from a longitudinal study of human infants and families followed from birth (N = 1,292) who faced high levels of poverty-related scarcity-adversity. Cross-species results supported the hypothesis that altered caregiving is one pathway by which poverty adversely impacts development. Rodent mothers assigned to the scarcity-adversity condition exhibited decreased sensitive parenting and increased negative parenting relative to mothers assigned to the control condition. Furthermore, scarcity-adversity reared pups exhibited decreased developmental competence as indicated by disrupted nipple attachment, distress vocalization when in physical contact with an anesthetized mother, and reduced preference for maternal odor with corresponding changes in brain activation. Human results indicated that scarcity-adversity was inversely correlated with sensitive parenting and positively correlated with negative parenting, and that parenting fully mediated the association of poverty-related risk with infant indicators of developmental competence. Findings are discussed from the perspective of the usefulness of bidirectional–translational research to inform interventions for at-risk families. En ligne : http://dx.doi.org/10.1017/S095457941800007X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393

Elevated infant cortisol is necessary but not sufficient for transmission of environmental risk to infant social development: Cross-species evidence of mother-infant physiological social transmission / Rosemarie E. PERRY in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1696-1714 Titre : Elevated infant cortisol is necessary but not sufficient for transmission of environmental risk to infant social development: Cross-species evidence of mother-infant physiological social transmission Type de document : Texte imprimé et/ou numérique Auteurs : Rosemarie E. PERRY, Auteur ; Stephen H. BRAREN, Auteur ; Maya OPENDAK, Auteur ; Annie BRANDES-AITKEN, Auteur ; Divija CHOPRA, Auteur ; Joyce WOO, Auteur ; Regina SULLIVAN, Auteur ; Clancy BLAIR, Auteur Article en page(s) : p.1696-1714 Langues : Anglais (eng) Mots-clés : Corticosterone  Female  Humans  *Hydrocortisone  Infant  Mother-Child Relations  *Mothers  Parenting  Stress, Psychological  *corticosterone  *cortisol  *early-life adversity  *early-life stress  *mother–infant  *social transmission Index. décimale : PER Périodiques Résumé : Environmental adversity increases child susceptibility to disrupted developmental outcomes, but the mechanisms by which adversity can shape development remain unclear. A translational cross-species approach was used to examine stress-mediated pathways by which poverty-related adversity can influence infant social development. Findings from a longitudinal sample of low-income mother-infant dyads indicated that infant cortisol (CORT) on its own did not mediate relations between early-life scarcity-adversity exposure and later infant behavior in a mother-child interaction task. However, maternal CORT through infant CORT served as a mediating pathway, even when controlling for parenting behavior. Findings using a rodent "scarcity-adversity" model indicated that pharmacologically blocking pup corticosterone (CORT, rodent equivalent to cortisol) in the presence of a stressed mother causally prevented social transmission of scarcity-adversity effects on pup social behavior. Furthermore, pharmacologically increasing pup CORT without the mother present was not sufficient to disrupt pup social behavior. Integration of our cross-species results suggests that elevated infant CORT may be necessary, but without elevated caregiver CORT, may not be sufficient in mediating the effects of environmental adversity on development. These findings underscore the importance of considering infant stress physiology in relation to the broader social context, including caregiver stress physiology, in research and interventional efforts. En ligne : http://dx.doi.org/10.1017/s0954579420001455 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] Elevated infant cortisol is necessary but not sufficient for transmission of environmental risk to infant social development: Cross-species evidence of mother-infant physiological social transmission [Texte imprimé et/ou numérique] / Rosemarie E. PERRY, Auteur ; Stephen H. BRAREN, Auteur ; Maya OPENDAK, Auteur ; Annie BRANDES-AITKEN, Auteur ; Divija CHOPRA, Auteur ; Joyce WOO, Auteur ; Regina SULLIVAN, Auteur ; Clancy BLAIR, Auteur . - p.1696-1714. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1696-1714 Mots-clés : Corticosterone  Female  Humans  *Hydrocortisone  Infant  Mother-Child Relations  *Mothers  Parenting  Stress, Psychological  *corticosterone  *cortisol  *early-life adversity  *early-life stress  *mother–infant  *social transmission Index. décimale : PER Périodiques Résumé : Environmental adversity increases child susceptibility to disrupted developmental outcomes, but the mechanisms by which adversity can shape development remain unclear. A translational cross-species approach was used to examine stress-mediated pathways by which poverty-related adversity can influence infant social development. Findings from a longitudinal sample of low-income mother-infant dyads indicated that infant cortisol (CORT) on its own did not mediate relations between early-life scarcity-adversity exposure and later infant behavior in a mother-child interaction task. However, maternal CORT through infant CORT served as a mediating pathway, even when controlling for parenting behavior. Findings using a rodent "scarcity-adversity" model indicated that pharmacologically blocking pup corticosterone (CORT, rodent equivalent to cortisol) in the presence of a stressed mother causally prevented social transmission of scarcity-adversity effects on pup social behavior. Furthermore, pharmacologically increasing pup CORT without the mother present was not sufficient to disrupt pup social behavior. Integration of our cross-species results suggests that elevated infant CORT may be necessary, but without elevated caregiver CORT, may not be sufficient in mediating the effects of environmental adversity on development. These findings underscore the importance of considering infant stress physiology in relation to the broader social context, including caregiver stress physiology, in research and interventional efforts. En ligne : http://dx.doi.org/10.1017/s0954579420001455 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437

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