The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder / Marilena M. DEMAYO in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1211-1222 Titre : The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Marilena M. DEMAYO, Auteur ; Izabella POKORSKI, Auteur ; Yun Ju C. SONG, Auteur ; Rinku THAPA, Auteur ; Shrujna PATEL, Auteur ; Zahava AMBARCHI, Auteur ; Domenic SOLIGO, Auteur ; Indra SADELI, Auteur ; Emma E. THOMAS, Auteur ; Ian B. HICKIE, Auteur ; Adam J. GUASTELLA, Auteur Article en page(s) : p.1211-1222 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain  Child  Child, Preschool  Feasibility Studies  Humans  Magnetic Resonance Imaging/methods  Autism spectrum disorders  Biomarkers  Brain function  Brain structure  Clinical trial  Interventions–pharmacologic  Magnetic resonance imaging  Neuroimaging  Pre-school children  School-age children Index. décimale : PER Périodiques Résumé : There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial. En ligne : http://dx.doi.org/10.1007/s10803-021-05028-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder [texte imprimé] / Marilena M. DEMAYO, Auteur ; Izabella POKORSKI, Auteur ; Yun Ju C. SONG, Auteur ; Rinku THAPA, Auteur ; Shrujna PATEL, Auteur ; Zahava AMBARCHI, Auteur ; Domenic SOLIGO, Auteur ; Indra SADELI, Auteur ; Emma E. THOMAS, Auteur ; Ian B. HICKIE, Auteur ; Adam J. GUASTELLA, Auteur . - p.1211-1222. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1211-1222 Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain  Child  Child, Preschool  Feasibility Studies  Humans  Magnetic Resonance Imaging/methods  Autism spectrum disorders  Biomarkers  Brain function  Brain structure  Clinical trial  Interventions–pharmacologic  Magnetic resonance imaging  Neuroimaging  Pre-school children  School-age children Index. décimale : PER Périodiques Résumé : There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial. En ligne : http://dx.doi.org/10.1007/s10803-021-05028-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

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