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Auteur Guang YANG
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Documents disponibles écrits par cet auteur (2)
Faire une suggestion Affiner la rechercheDaily Mindfulness and Depressive Symptoms Among Parents of Autistic Children: A Dynamic Structural Equation Modelling Study / Lin WANG in Autism, 30-6 (June 2026)
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[article]
Titre : Daily Mindfulness and Depressive Symptoms Among Parents of Autistic Children: A Dynamic Structural Equation Modelling Study Type de document : texte imprimé Auteurs : Lin WANG, Auteur ; Meng HUA, Auteur ; Xinyi HU, Auteur ; Yifan WANG, Auteur ; Qinxing XIE, Auteur ; Guang YANG, Auteur ; Yuan CHEN, Auteur Article en page(s) : p.1576-1592 Langues : Anglais (eng) Mots-clés : child externalising problems daily diary study depressive symptoms dynamic structural equation modelling mindfulness parents of autistic children perceived social support Index. décimale : PER Périodiques Résumé : Elevated depressive symptoms among parents of autistic children are well documented and associated with poorer mental health. Mindfulness has been identified as a protective factor against mental health difficulties, but its day-to-day associations with depressive symptoms in this population remain unclear. A total of 210 Chinese parents of autistic children participated in this 15-day diary study, during which they completed daily measures of mindfulness and depressive symptoms. The data were analysed using dynamic structural equation modelling. Results indicated that (1) parents’ daily mindfulness and depressive symptoms exhibited autoregressive stability and showed significant negative reciprocal cross-lagged associations at the within-person level. At the between-person level, (2) higher perceived social support was associated with lower mean depressive symptoms and higher mean mindfulness, and it strengthened the negative cross-lagged effect of daily mindfulness on next-day depressive symptoms; and (3) child externalising problems were positively associated with parents’ overall mean depressive symptoms and negatively associated with both parents’ overall mean daily mindfulness and the autoregressive effects of daily mindfulness and depressive symptoms. Findings underscore the importance of fostering daily mindfulness within a supportive resource context and highlight the need to maintain the day-to-day persistence of mindfulness in families of autistic children with higher externalising problems.Lay Abstract Parents of autistic children tended to feel fewer depressive symptoms on the day after they felt more mindful; likewise, they tended to feel less mindful the day after they felt more depressed. We asked 210 parents in China to complete a short daily questionnaire for 15 days about their daily mindfulness and depressive symptoms. We also looked at two factors that might affect day-to-day mindfulness and depressive symptoms: the level of perceived social support and children’s challenging externalising behaviours directed towards parents. We focused on how parents’ mindfulness and depressive symptoms shift from one day to the next to identify practical ways to improve parents’ mental well-being. We found that more perceived social support was linked to a stronger next-day connection between feeling more mindful and feeling less depressed, whereas more frequent behavioural challenges were linked to more ups and downs from one day to the next in both mindfulness and mood. The findings of this work can guide researchers and practitioners to design simple, everyday actions, such as brief mindfulness moments and better support for families, that help parents feel less low from one day to the next. En ligne : https://dx.doi.org/10.1177/13623613261439930 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586
in Autism > 30-6 (June 2026) . - p.1576-1592[article] Daily Mindfulness and Depressive Symptoms Among Parents of Autistic Children: A Dynamic Structural Equation Modelling Study [texte imprimé] / Lin WANG, Auteur ; Meng HUA, Auteur ; Xinyi HU, Auteur ; Yifan WANG, Auteur ; Qinxing XIE, Auteur ; Guang YANG, Auteur ; Yuan CHEN, Auteur . - p.1576-1592.
Langues : Anglais (eng)
in Autism > 30-6 (June 2026) . - p.1576-1592
Mots-clés : child externalising problems daily diary study depressive symptoms dynamic structural equation modelling mindfulness parents of autistic children perceived social support Index. décimale : PER Périodiques Résumé : Elevated depressive symptoms among parents of autistic children are well documented and associated with poorer mental health. Mindfulness has been identified as a protective factor against mental health difficulties, but its day-to-day associations with depressive symptoms in this population remain unclear. A total of 210 Chinese parents of autistic children participated in this 15-day diary study, during which they completed daily measures of mindfulness and depressive symptoms. The data were analysed using dynamic structural equation modelling. Results indicated that (1) parents’ daily mindfulness and depressive symptoms exhibited autoregressive stability and showed significant negative reciprocal cross-lagged associations at the within-person level. At the between-person level, (2) higher perceived social support was associated with lower mean depressive symptoms and higher mean mindfulness, and it strengthened the negative cross-lagged effect of daily mindfulness on next-day depressive symptoms; and (3) child externalising problems were positively associated with parents’ overall mean depressive symptoms and negatively associated with both parents’ overall mean daily mindfulness and the autoregressive effects of daily mindfulness and depressive symptoms. Findings underscore the importance of fostering daily mindfulness within a supportive resource context and highlight the need to maintain the day-to-day persistence of mindfulness in families of autistic children with higher externalising problems.Lay Abstract Parents of autistic children tended to feel fewer depressive symptoms on the day after they felt more mindful; likewise, they tended to feel less mindful the day after they felt more depressed. We asked 210 parents in China to complete a short daily questionnaire for 15 days about their daily mindfulness and depressive symptoms. We also looked at two factors that might affect day-to-day mindfulness and depressive symptoms: the level of perceived social support and children’s challenging externalising behaviours directed towards parents. We focused on how parents’ mindfulness and depressive symptoms shift from one day to the next to identify practical ways to improve parents’ mental well-being. We found that more perceived social support was linked to a stronger next-day connection between feeling more mindful and feeling less depressed, whereas more frequent behavioural challenges were linked to more ups and downs from one day to the next in both mindfulness and mood. The findings of this work can guide researchers and practitioners to design simple, everyday actions, such as brief mindfulness moments and better support for families, that help parents feel less low from one day to the next. En ligne : https://dx.doi.org/10.1177/13623613261439930 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586 Depicting the composition of gut microbiota in children with tic disorders: an exploratory study / Wenjie XI in Journal of Child Psychology and Psychiatry, 62-10 (October 2021)
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Titre : Depicting the composition of gut microbiota in children with tic disorders: an exploratory study Type de document : texte imprimé Auteurs : Wenjie XI, Auteur ; Xuefeng GAO, Auteur ; Huijun ZHAO, Auteur ; Xuerong LUO, Auteur ; Jun LI, Auteur ; Xinjie TAN, Auteur ; Lifang WANG, Auteur ; Jian-Bo ZHAO, Auteur ; Jing WANG, Auteur ; Guang YANG, Auteur ; Li-Ying LIU, Auteur ; Yang-Yang WANG, Auteur ; Lilhua PENG, Auteur ; Li-Ping ZOU, Auteur ; Yongjie YANG, Auteur Année de publication : 2021 Article en page(s) : p.1246-1254 Langues : Anglais (eng) Mots-clés : Bacteroides Child Gastrointestinal Microbiome Humans Prevotella Ruminococcus Streptococcus Tic Disorders dopamine receptor antagonists gut microbiota metabolic pathways metagenomics Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptom improvement in children with tic disorder (TD) following fecal microbiota transplantation led us to investigate the gut microbiota in TD. This exploratory study aims to depict the gut microbial profile in patients with TD and explore the impact of dopamine receptor antagonist (DRA) drugs on the composition and metabolic function of the gut microbiota. METHODS: The gut microbiota were profiled in fecal samples of 49 children with TD and 50 matched healthy controls (HC) using shotgun metagenomic sequencing. A random forest (RF) model was constructed using the gut bacterial species to distinguish TD from HC. Associations between clinical metadata and microbial abundance or function were analyzed using MaAsLin2 and Spearman correlation. RESULTS: The gut microbiota in children with TD was featured by higher abundances of Bacteroides plebeius and Ruminococcus lactaris (a potential pro-inflammatory taxon) and lower abundances of Prevotella stercorea and Streptococcus lutetiensis compared to HC. The constructed RF model accurately distinguished TD from HC based on the gut microbiota profile, resulting in an AUC of 0.884. Significant correlations were observed between tic symptom severity and the abundances of multiple bacterial species and gut microbiota metabolic functions. Multivariate analysis identified an upregulation of 4-aminobutanoate (GABA) degradation in the gut microbiota associated with TD status. The gut microbiota of DRA-treated TD children showed a distinct gut microbiota compared to the treatment-naïve group, represented by an increase in some potential enteric pathogens such as Escherichia coli, a decline in several species including Akkermansia muciniphila, and alterations in various metabolic functions. CONCLUSIONS: Bacterial species promoting inflammatory responses and those modulating neurotransmitters such as GABA may be involved in the pathogenesis of TD. The use of DRA drugs is likely to induce overgrowth of some enteric pathogens and alter the gut microbiota metabolism. En ligne : http://dx.doi.org/10.1111/jcpp.13409 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1246-1254[article] Depicting the composition of gut microbiota in children with tic disorders: an exploratory study [texte imprimé] / Wenjie XI, Auteur ; Xuefeng GAO, Auteur ; Huijun ZHAO, Auteur ; Xuerong LUO, Auteur ; Jun LI, Auteur ; Xinjie TAN, Auteur ; Lifang WANG, Auteur ; Jian-Bo ZHAO, Auteur ; Jing WANG, Auteur ; Guang YANG, Auteur ; Li-Ying LIU, Auteur ; Yang-Yang WANG, Auteur ; Lilhua PENG, Auteur ; Li-Ping ZOU, Auteur ; Yongjie YANG, Auteur . - 2021 . - p.1246-1254.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1246-1254
Mots-clés : Bacteroides Child Gastrointestinal Microbiome Humans Prevotella Ruminococcus Streptococcus Tic Disorders dopamine receptor antagonists gut microbiota metabolic pathways metagenomics Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptom improvement in children with tic disorder (TD) following fecal microbiota transplantation led us to investigate the gut microbiota in TD. This exploratory study aims to depict the gut microbial profile in patients with TD and explore the impact of dopamine receptor antagonist (DRA) drugs on the composition and metabolic function of the gut microbiota. METHODS: The gut microbiota were profiled in fecal samples of 49 children with TD and 50 matched healthy controls (HC) using shotgun metagenomic sequencing. A random forest (RF) model was constructed using the gut bacterial species to distinguish TD from HC. Associations between clinical metadata and microbial abundance or function were analyzed using MaAsLin2 and Spearman correlation. RESULTS: The gut microbiota in children with TD was featured by higher abundances of Bacteroides plebeius and Ruminococcus lactaris (a potential pro-inflammatory taxon) and lower abundances of Prevotella stercorea and Streptococcus lutetiensis compared to HC. The constructed RF model accurately distinguished TD from HC based on the gut microbiota profile, resulting in an AUC of 0.884. Significant correlations were observed between tic symptom severity and the abundances of multiple bacterial species and gut microbiota metabolic functions. Multivariate analysis identified an upregulation of 4-aminobutanoate (GABA) degradation in the gut microbiota associated with TD status. The gut microbiota of DRA-treated TD children showed a distinct gut microbiota compared to the treatment-naïve group, represented by an increase in some potential enteric pathogens such as Escherichia coli, a decline in several species including Akkermansia muciniphila, and alterations in various metabolic functions. CONCLUSIONS: Bacterial species promoting inflammatory responses and those modulating neurotransmitters such as GABA may be involved in the pathogenesis of TD. The use of DRA drugs is likely to induce overgrowth of some enteric pathogens and alter the gut microbiota metabolism. En ligne : http://dx.doi.org/10.1111/jcpp.13409 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

