The impact of adverse childhood events on service support and educational outcomes of children who are autistic: A theory-guided analysis using structural equation modeling / Micah HARTWELL in Autism Research, 17-4 (April 2024)  

Public ISBD [article]  inAutism Research > 17-4 (April 2024) . - p.739-746 Titre : The impact of adverse childhood events on service support and educational outcomes of children who are autistic: A theory-guided analysis using structural equation modeling Type de document : Texte imprimé et/ou numérique Auteurs : Micah HARTWELL, Auteur ; Kelsi BATIOJA, Auteur ; Covenant ELENWO, Auteur ; Ashley KEENER, Auteur ; Anya MAZUR, Auteur ; Tessa CHESHER, Auteur Article en page(s) : p.739-746 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Autistic children who have experienced adverse childhood experiences (ACEs) may have barriers to receiving special education or other developmental services-thus, impacting educational outcomes. Our objective was to model such a pathway using the 2016-2021 National Survey of Children's Health datasets. We extracted data for school outcomes, use of special education and autism-related specialty services and sociodemographic characteristics among autistic children within the data. Associations between sociodemographics and ACEs (categorized as 0, 1-3, and 4+) were tested using design-based X2 tests. We then used structural equation modeling to map the quasi-causal pathways. The sample for our analysis included 4717 autistic children-38.94% were aged 6-10?years, 35.73% of children aged 11-14?years, and 25.32% were between 15 and 17?years-with 88.70% living in metropolitan areas. The X2 showed significant relationships between ACEs and age, ethnoracial groups, and urbanicity among others. The SEM showed ACEs were directly associated with poorer school outcomes (? = ?0.14 (0.04), p = 0.002) and through their inverse relationship with support services (? = ?0.08 (0.04), p = 0.023)- when support services were increased, school outcomes improved (? = 0.62, p < 0.001). Findings suggested ACEs have a significant direct and indirect impact on school outcomes of autistic children, and 10.76% of children who are autistic have experienced four or more ACEs-which were more likely to occur with severe autism symptomatology and in rural areas. Results highlight the need for communities to recognize the potential long-term impact of ACEs on the academic outcomes of autistic children. En ligne : https://doi.org/10.1002/aur.3126 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] The impact of adverse childhood events on service support and educational outcomes of children who are autistic: A theory-guided analysis using structural equation modeling [Texte imprimé et/ou numérique] / Micah HARTWELL, Auteur ; Kelsi BATIOJA, Auteur ; Covenant ELENWO, Auteur ; Ashley KEENER, Auteur ; Anya MAZUR, Auteur ; Tessa CHESHER, Auteur . - p.739-746. Langues : Anglais (eng) in Autism Research > 17-4 (April 2024) . - p.739-746 Index. décimale : PER Périodiques Résumé : Abstract Autistic children who have experienced adverse childhood experiences (ACEs) may have barriers to receiving special education or other developmental services-thus, impacting educational outcomes. Our objective was to model such a pathway using the 2016-2021 National Survey of Children's Health datasets. We extracted data for school outcomes, use of special education and autism-related specialty services and sociodemographic characteristics among autistic children within the data. Associations between sociodemographics and ACEs (categorized as 0, 1-3, and 4+) were tested using design-based X2 tests. We then used structural equation modeling to map the quasi-causal pathways. The sample for our analysis included 4717 autistic children-38.94% were aged 6-10?years, 35.73% of children aged 11-14?years, and 25.32% were between 15 and 17?years-with 88.70% living in metropolitan areas. The X2 showed significant relationships between ACEs and age, ethnoracial groups, and urbanicity among others. The SEM showed ACEs were directly associated with poorer school outcomes (? = ?0.14 (0.04), p = 0.002) and through their inverse relationship with support services (? = ?0.08 (0.04), p = 0.023)- when support services were increased, school outcomes improved (? = 0.62, p < 0.001). Findings suggested ACEs have a significant direct and indirect impact on school outcomes of autistic children, and 10.76% of children who are autistic have experienced four or more ACEs-which were more likely to occur with severe autism symptomatology and in rural areas. Results highlight the need for communities to recognize the potential long-term impact of ACEs on the academic outcomes of autistic children. En ligne : https://doi.org/10.1002/aur.3126 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

The impact of COVID-19 on autism research: A cross-sectional analysis of discontinued or suspended clinical trials / Monika NEALE in Autism Research, 15-8 (August 2022)  

Public ISBD [article]  inAutism Research > 15-8 (August 2022) . - p.1560-1564 Titre : The impact of COVID-19 on autism research: A cross-sectional analysis of discontinued or suspended clinical trials Type de document : Texte imprimé et/ou numérique Auteurs : Monika NEALE, Auteur ; Elizabeth LANDERS, Auteur ; Nicholas B. SAJJADI, Auteur ; Anya MAZUR-MOSIEWICZ, Auteur ; Micah HARTWELL, Auteur Article en page(s) : p.1560-1564 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/epidemiology  Autistic Disorder/epidemiology  covid-19  Cross-Sectional Studies  Humans  Pandemics  Covid-19  autism  clinical trials  discontinuation  pandemic Index. décimale : PER Périodiques Résumé : Due to uncertainties associated with the COVID-19 public health crisis, several clinical trials had to be withdrawn or postponed. Our investigation aimed to assess the rate of discontinuation of clinical trials focusing on Autism Spectrum Disorder. Of the 197 registered trials included in our systematic review, 15 (7.6%) were discontinued, with nearly half of these explicitly citing COVID-19 as their reason for discontinuation. Pharmacological trials were six times more likely to be discontinued during the pandemic than non-pharmacological studies. The difference between the likelihood of discontinuation was statistically significant (OR: 6.13; 95% CI: 1.22-30.71). There was no evidence of association between funding source and reasons for discontinuation. Limitations, along with implications for future trials are discussed. LAY SUMMARY: We investigated the impact of the COVID-19 pandemic on the discontinuation rate of autism clinical trials. We found that drug trials were six times more likely to be discontinued during the pandemic compared to behavioral, diagnostic, and nutritional trials. The overall discontinuation rate was notably lower in autism clinical trials than in other areas of medical research. We recommend an examination of the methodology of the continued autism trials to assess their applicability in other fields. En ligne : http://dx.doi.org/10.1002/aur.2764 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 [article] The impact of COVID-19 on autism research: A cross-sectional analysis of discontinued or suspended clinical trials [Texte imprimé et/ou numérique] / Monika NEALE, Auteur ; Elizabeth LANDERS, Auteur ; Nicholas B. SAJJADI, Auteur ; Anya MAZUR-MOSIEWICZ, Auteur ; Micah HARTWELL, Auteur . - p.1560-1564. Langues : Anglais (eng) in Autism Research > 15-8 (August 2022) . - p.1560-1564 Mots-clés : Autism Spectrum Disorder/epidemiology  Autistic Disorder/epidemiology  covid-19  Cross-Sectional Studies  Humans  Pandemics  Covid-19  autism  clinical trials  discontinuation  pandemic Index. décimale : PER Périodiques Résumé : Due to uncertainties associated with the COVID-19 public health crisis, several clinical trials had to be withdrawn or postponed. Our investigation aimed to assess the rate of discontinuation of clinical trials focusing on Autism Spectrum Disorder. Of the 197 registered trials included in our systematic review, 15 (7.6%) were discontinued, with nearly half of these explicitly citing COVID-19 as their reason for discontinuation. Pharmacological trials were six times more likely to be discontinued during the pandemic than non-pharmacological studies. The difference between the likelihood of discontinuation was statistically significant (OR: 6.13; 95% CI: 1.22-30.71). There was no evidence of association between funding source and reasons for discontinuation. Limitations, along with implications for future trials are discussed. LAY SUMMARY: We investigated the impact of the COVID-19 pandemic on the discontinuation rate of autism clinical trials. We found that drug trials were six times more likely to be discontinued during the pandemic compared to behavioral, diagnostic, and nutritional trials. The overall discontinuation rate was notably lower in autism clinical trials than in other areas of medical research. We recommend an examination of the methodology of the continued autism trials to assess their applicability in other fields. En ligne : http://dx.doi.org/10.1002/aur.2764 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483

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