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Auteur Megan MIKHAIL
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Documents disponibles écrits par cet auteur (2)
Faire une suggestion Affiner la rechercheExploring the possibility of parents’ broad internalizing phenotype acting through passive gene–environment correlations on daughters’ disordered eating / Shannon M. O’CONNOR in Development and Psychopathology, 34-5 (December 2022)
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[article]
Titre : Exploring the possibility of parents’ broad internalizing phenotype acting through passive gene–environment correlations on daughters’ disordered eating Type de document : texte imprimé Auteurs : Shannon M. O’CONNOR, Auteur ; Megan MIKHAIL, Auteur ; Carolina ANAYA, Auteur ; Leora L. HALLER, Auteur ; S. Alexandra BURT, Auteur ; Matt MCGUE, Auteur ; William G. IACONO, Auteur ; Kelly L. KLUMP, Auteur Article en page(s) : p.1744-1755 Langues : Anglais (eng) Mots-clés : Disordered eating eating disorders family twin study internalizing Index. décimale : PER Périodiques Résumé : Twin studies demonstrate significant environmental influences and a lack of genetic effects on disordered eating before puberty in girls. However, genetic factors could act indirectly through passive gene “environment correlations (rGE; correlations between parents’ genes and an environment shaped by those genes) that inflate environmental (but not genetic) estimates. The only study to explore passive rGE did not find significant effects, but the full range of parental phenotypes (e.g., internalizing symptoms) that could impact daughters’ disordered eating was not examined. We addressed this gap by exploring whether parents’ internalizing symptoms (e.g., anxiety, depressive symptoms) contribute to daughters’ eating pathology through passive rGE. Participants were female twin pairs (aged 8 “14 years; M = 10.44) in pre-early puberty and their biological parents (n = 279 families) from the Michigan State University Twin Registry. Nuclear twin family models explored passive rGE for parents’ internalizing traits/symptoms and twins’ overall eating disorder symptoms. No evidence for passive rGE was found. Instead, environmental factors that create similarities between co-twins (but not with their parents) and unique environmental factors were important. In pre-early puberty, genetic factors do not influence daughters’ disordered eating, even indirectly through passive rGE. Future research should explore sibling-specific and unique environmental factors during this critical developmental period. En ligne : http://dx.doi.org/10.1017/S0954579422000608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492
in Development and Psychopathology > 34-5 (December 2022) . - p.1744-1755[article] Exploring the possibility of parents’ broad internalizing phenotype acting through passive gene–environment correlations on daughters’ disordered eating [texte imprimé] / Shannon M. O’CONNOR, Auteur ; Megan MIKHAIL, Auteur ; Carolina ANAYA, Auteur ; Leora L. HALLER, Auteur ; S. Alexandra BURT, Auteur ; Matt MCGUE, Auteur ; William G. IACONO, Auteur ; Kelly L. KLUMP, Auteur . - p.1744-1755.
Langues : Anglais (eng)
in Development and Psychopathology > 34-5 (December 2022) . - p.1744-1755
Mots-clés : Disordered eating eating disorders family twin study internalizing Index. décimale : PER Périodiques Résumé : Twin studies demonstrate significant environmental influences and a lack of genetic effects on disordered eating before puberty in girls. However, genetic factors could act indirectly through passive gene “environment correlations (rGE; correlations between parents’ genes and an environment shaped by those genes) that inflate environmental (but not genetic) estimates. The only study to explore passive rGE did not find significant effects, but the full range of parental phenotypes (e.g., internalizing symptoms) that could impact daughters’ disordered eating was not examined. We addressed this gap by exploring whether parents’ internalizing symptoms (e.g., anxiety, depressive symptoms) contribute to daughters’ eating pathology through passive rGE. Participants were female twin pairs (aged 8 “14 years; M = 10.44) in pre-early puberty and their biological parents (n = 279 families) from the Michigan State University Twin Registry. Nuclear twin family models explored passive rGE for parents’ internalizing traits/symptoms and twins’ overall eating disorder symptoms. No evidence for passive rGE was found. Instead, environmental factors that create similarities between co-twins (but not with their parents) and unique environmental factors were important. In pre-early puberty, genetic factors do not influence daughters’ disordered eating, even indirectly through passive rGE. Future research should explore sibling-specific and unique environmental factors during this critical developmental period. En ligne : http://dx.doi.org/10.1017/S0954579422000608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 Identifying the 'active ingredients' of socioeconomic disadvantage for youth outcomes in middle childhood / Elizabeth A. SHEWARK ; Megan MIKHAIL ; Daniel J. THALER ; Amber L. PEARSON ; Kelly L. KLUMP ; S. Alexandra BURT in Development and Psychopathology, 36-2 (May 2024)
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[article]
Titre : Identifying the 'active ingredients' of socioeconomic disadvantage for youth outcomes in middle childhood Type de document : texte imprimé Auteurs : Elizabeth A. SHEWARK, Auteur ; Megan MIKHAIL, Auteur ; Daniel J. THALER, Auteur ; Amber L. PEARSON, Auteur ; Kelly L. KLUMP, Auteur ; S. Alexandra BURT, Auteur Article en page(s) : p.857-865 Langues : Anglais (eng) Mots-clés : academic achievement ecological model neighborhood context socioeconomic disadvantage youth psychopathology Index. décimale : PER Périodiques Résumé : Background:Youth experiencing socioeconomic deprivation may be exposed to disadvantage in multiple contexts (e.g., neighborhood, family, and school). To date, however, we know little about the underlying structure of socioeconomic disadvantage, including whether the 'active ingredients' driving its robust effects are specific to one context (e.g., neighborhood) or whether the various contexts increment one another as predictors of youth outcomes.Methods:The present study addressed this gap by examining the underlying structure of socioeconomic disadvantage across neighborhoods, families, and schools, as well as whether the various forms of disadvantage jointly predicted youth psychopathology and cognitive performance. Participants were 1,030 school-aged twin pairs from a subsample of the Michigan State University Twin Registry enriched for neighborhood disadvantage.Results:Two correlated factors underlay the indicators of disadvantage. Proximal disadvantage comprised familial indicators, whereas contextual disadvantage represented deprivation in the broader school and neighborhood contexts. Results from exhaustive modeling analyses indicated that proximal and contextual disadvantage incremented one another as predictors of childhood externalizing problems, disordered eating, and reading difficulties, but not internalizing symptoms.Conclusions:Disadvantage within the family and disadvantage in the broader context, respectively, appear to represent distinct constructs with additive influence, carrying unique implications for multiple behavioral outcomes during middle childhood. En ligne : https://dx.doi.org/10.1017/S0954579423000135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528
in Development and Psychopathology > 36-2 (May 2024) . - p.857-865[article] Identifying the 'active ingredients' of socioeconomic disadvantage for youth outcomes in middle childhood [texte imprimé] / Elizabeth A. SHEWARK, Auteur ; Megan MIKHAIL, Auteur ; Daniel J. THALER, Auteur ; Amber L. PEARSON, Auteur ; Kelly L. KLUMP, Auteur ; S. Alexandra BURT, Auteur . - p.857-865.
Langues : Anglais (eng)
in Development and Psychopathology > 36-2 (May 2024) . - p.857-865
Mots-clés : academic achievement ecological model neighborhood context socioeconomic disadvantage youth psychopathology Index. décimale : PER Périodiques Résumé : Background:Youth experiencing socioeconomic deprivation may be exposed to disadvantage in multiple contexts (e.g., neighborhood, family, and school). To date, however, we know little about the underlying structure of socioeconomic disadvantage, including whether the 'active ingredients' driving its robust effects are specific to one context (e.g., neighborhood) or whether the various contexts increment one another as predictors of youth outcomes.Methods:The present study addressed this gap by examining the underlying structure of socioeconomic disadvantage across neighborhoods, families, and schools, as well as whether the various forms of disadvantage jointly predicted youth psychopathology and cognitive performance. Participants were 1,030 school-aged twin pairs from a subsample of the Michigan State University Twin Registry enriched for neighborhood disadvantage.Results:Two correlated factors underlay the indicators of disadvantage. Proximal disadvantage comprised familial indicators, whereas contextual disadvantage represented deprivation in the broader school and neighborhood contexts. Results from exhaustive modeling analyses indicated that proximal and contextual disadvantage incremented one another as predictors of childhood externalizing problems, disordered eating, and reading difficulties, but not internalizing symptoms.Conclusions:Disadvantage within the family and disadvantage in the broader context, respectively, appear to represent distinct constructs with additive influence, carrying unique implications for multiple behavioral outcomes during middle childhood. En ligne : https://dx.doi.org/10.1017/S0954579423000135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528

