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Auteur Christine Wu NORDAHL |
Documents disponibles écrits par cet auteur (5)



Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder / Konnor DAVIS in Journal of Autism and Developmental Disorders, 53-3 (March 2023)
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Titre : Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine Wu NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur Article en page(s) : p.1301-1301 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05694-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500
in Journal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.1301-1301[article] Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine Wu NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur . - p.1301-1301.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.1301-1301
Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05694-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500 Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability / Derek S. ANDREWS in Autism Research, 18-3 (March 2025)
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Titre : Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability Type de document : Texte imprimé et/ou numérique Auteurs : Derek S. ANDREWS, Auteur ; Andrew J. DAKOPOLOS, Auteur ; Joshua K. LEE, Auteur ; Brianna HEATH, Auteur ; Devani CORDERO, Auteur ; Marjorie SOLOMON, Auteur ; David G. AMARAL, Auteur ; Christine Wu NORDAHL, Auteur Article en page(s) : p.486-497 Langues : Anglais (eng) Mots-clés : autism cortical thickness intellectual disability IQ MRI Index. décimale : PER Périodiques Résumé : ABSTRACT Of the 1 in 36 individuals in the United States who are diagnosed with autism spectrum disorder, nearly 40% also have intellectual disability (ID). The cortex has been widely implicated in neural processes underlying autistic behaviors as well as intellectual ability. Thus, neuroimaging features such as cortical thickness are of particular interest as a possible biomarkers of the condition. However, neuroimaging studies often fail to include autistic individuals with ID. As a result, there are few studies of cortical thickness in autistic individuals across the entire range of intellectual abilities. This study used MRI to evaluate cortical thickness in young autistic children (n?=?88, mean age 5.37?years) with a large range of intellectual ability (IQ 19?133) as well as nonautistic, nondevelopmentally delayed (referred to here as typically developing [TD]) peers (n?=?53, mean age 5.29?years). We first investigated associations between full scale IQ and cortical thickness in both autistic and TD children. Autistic children had significant negative associations (i.e., thinner cortex, higher IQ) in bilateral entorhinal cortex, right fusiform gyrus, superior, middle and inferior temporal gyri, and right temporal pole that were not present in TD children. Significantly thicker cortex was also observed in these regions for autistic children with ID (i.e., IQ???70) compared with those without. Last, given the reported correspondence between the severity of autism symptoms and intellectual ability, we compared cortical thickness associations with both IQ and ADOS Calibrated Severity Scores and found these patterns overlapped to a significant degree across the cortex. En ligne : https://doi.org/10.1002/aur.3313 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550
in Autism Research > 18-3 (March 2025) . - p.486-497[article] Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability [Texte imprimé et/ou numérique] / Derek S. ANDREWS, Auteur ; Andrew J. DAKOPOLOS, Auteur ; Joshua K. LEE, Auteur ; Brianna HEATH, Auteur ; Devani CORDERO, Auteur ; Marjorie SOLOMON, Auteur ; David G. AMARAL, Auteur ; Christine Wu NORDAHL, Auteur . - p.486-497.
Langues : Anglais (eng)
in Autism Research > 18-3 (March 2025) . - p.486-497
Mots-clés : autism cortical thickness intellectual disability IQ MRI Index. décimale : PER Périodiques Résumé : ABSTRACT Of the 1 in 36 individuals in the United States who are diagnosed with autism spectrum disorder, nearly 40% also have intellectual disability (ID). The cortex has been widely implicated in neural processes underlying autistic behaviors as well as intellectual ability. Thus, neuroimaging features such as cortical thickness are of particular interest as a possible biomarkers of the condition. However, neuroimaging studies often fail to include autistic individuals with ID. As a result, there are few studies of cortical thickness in autistic individuals across the entire range of intellectual abilities. This study used MRI to evaluate cortical thickness in young autistic children (n?=?88, mean age 5.37?years) with a large range of intellectual ability (IQ 19?133) as well as nonautistic, nondevelopmentally delayed (referred to here as typically developing [TD]) peers (n?=?53, mean age 5.29?years). We first investigated associations between full scale IQ and cortical thickness in both autistic and TD children. Autistic children had significant negative associations (i.e., thinner cortex, higher IQ) in bilateral entorhinal cortex, right fusiform gyrus, superior, middle and inferior temporal gyri, and right temporal pole that were not present in TD children. Significantly thicker cortex was also observed in these regions for autistic children with ID (i.e., IQ???70) compared with those without. Last, given the reported correspondence between the severity of autism symptoms and intellectual ability, we compared cortical thickness associations with both IQ and ADOS Calibrated Severity Scores and found these patterns overlapped to a significant degree across the cortex. En ligne : https://doi.org/10.1002/aur.3313 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550 Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability / Andre SILLAS ; Melanie PRIETO ; Emily CAMP ; Christine Wu NORDAHL ; Susan M. RIVERA in Autism Research, 17-8 (August 2024)
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Titre : Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability Type de document : Texte imprimé et/ou numérique Auteurs : Andre SILLAS, Auteur ; Melanie PRIETO, Auteur ; Emily CAMP, Auteur ; Christine Wu NORDAHL, Auteur ; Susan M. RIVERA, Auteur Article en page(s) : p.1677-1695 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The autistic-developed monotropism account suggests that atypical, domain-general attentional hyper-focus on interests is a central aspect of autism, but domain-general attention differences in autism can manifest differently. Prior research suggests autistic children are often slow to disengage attention from stimuli-a pattern often called "sticky attention"-and that they can show reduced novelty preference. These attentional patterns could influence sensory experiences and learning. We used eye-tracking to investigate novelty preference and "sticky attention" in young autistic children; we also examined whether attentional patterns were related to cognitive abilities and caregiver-reported sensory responsiveness. A total of 46 autistic and 28 nonautistic participants, aged between 2 and 4?years, provided usable data. We found no evidence that autistic children exhibited greater "sticky attention" than nonautistics, but "sticky attention" in autism was associated with more caregiver-reported sensory hyper-responsiveness, seeking/interests, and enhanced perception. Autistic children also nonsignificantly trended toward exhibiting reduced novelty preference. Unexpectedly, the time-course of this trending novelty preference difference implied it was not driven by reduced orienting to novelty, but increased returning to already-familiarized stimuli: what we call "springy attention." Exploratory analyses of data from the attentional disengagement task suggest autistic participants may have exhibited greater "springy attention," though further research with paradigms optimized for measuring this construct should confirm this. Importantly, "springy attention" was robustly related to reduced cognitive abilities and greater caregiver-reported hypo-responsiveness. Thus, this study illuminates two distinct domain-general attentional patterns, each with distinct correlates in young autistic children, which could have important implications for understanding autistic children's learning, development, and experiences. En ligne : https://doi.org/10.1002/aur.3174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533
in Autism Research > 17-8 (August 2024) . - p.1677-1695[article] Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability [Texte imprimé et/ou numérique] / Andre SILLAS, Auteur ; Melanie PRIETO, Auteur ; Emily CAMP, Auteur ; Christine Wu NORDAHL, Auteur ; Susan M. RIVERA, Auteur . - p.1677-1695.
Langues : Anglais (eng)
in Autism Research > 17-8 (August 2024) . - p.1677-1695
Index. décimale : PER Périodiques Résumé : Abstract The autistic-developed monotropism account suggests that atypical, domain-general attentional hyper-focus on interests is a central aspect of autism, but domain-general attention differences in autism can manifest differently. Prior research suggests autistic children are often slow to disengage attention from stimuli-a pattern often called "sticky attention"-and that they can show reduced novelty preference. These attentional patterns could influence sensory experiences and learning. We used eye-tracking to investigate novelty preference and "sticky attention" in young autistic children; we also examined whether attentional patterns were related to cognitive abilities and caregiver-reported sensory responsiveness. A total of 46 autistic and 28 nonautistic participants, aged between 2 and 4?years, provided usable data. We found no evidence that autistic children exhibited greater "sticky attention" than nonautistics, but "sticky attention" in autism was associated with more caregiver-reported sensory hyper-responsiveness, seeking/interests, and enhanced perception. Autistic children also nonsignificantly trended toward exhibiting reduced novelty preference. Unexpectedly, the time-course of this trending novelty preference difference implied it was not driven by reduced orienting to novelty, but increased returning to already-familiarized stimuli: what we call "springy attention." Exploratory analyses of data from the attentional disengagement task suggest autistic participants may have exhibited greater "springy attention," though further research with paradigms optimized for measuring this construct should confirm this. Importantly, "springy attention" was robustly related to reduced cognitive abilities and greater caregiver-reported hypo-responsiveness. Thus, this study illuminates two distinct domain-general attentional patterns, each with distinct correlates in young autistic children, which could have important implications for understanding autistic children's learning, development, and experiences. En ligne : https://doi.org/10.1002/aur.3174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533 Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder / Konnor DAVIS in Journal of Autism and Developmental Disorders, 53-9 (September 2023)
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Titre : Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine Wu NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur Article en page(s) : p.3567-3580 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We used parent report data to investigate video game playing, aggression, and social impairment in adolescents with autism spectrum disorder. Parents of autistic adolescents were more likely to report that their child plays video games as a hobby compared to parents of adolescents with typical development and also reported that their children spent more time playing video games. For autistic participants, we found no differences in aggression levels or social impairment when comparing players versus non-players. However, playing video games "more than average," as compared to "average" was associated with greater aggression and greater social impairment on "awareness" and "mannerisms" subscales. Future studies should focus on how type of video game(s) played is associated with these clinically important variables. En ligne : https://doi.org/10.1007/s10803-022-05649-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511
in Journal of Autism and Developmental Disorders > 53-9 (September 2023) . - p.3567-3580[article] Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine Wu NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur . - p.3567-3580.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-9 (September 2023) . - p.3567-3580
Index. décimale : PER Périodiques Résumé : We used parent report data to investigate video game playing, aggression, and social impairment in adolescents with autism spectrum disorder. Parents of autistic adolescents were more likely to report that their child plays video games as a hobby compared to parents of adolescents with typical development and also reported that their children spent more time playing video games. For autistic participants, we found no differences in aggression levels or social impairment when comparing players versus non-players. However, playing video games "more than average," as compared to "average" was associated with greater aggression and greater social impairment on "awareness" and "mannerisms" subscales. Future studies should focus on how type of video game(s) played is associated with these clinically important variables. En ligne : https://doi.org/10.1007/s10803-022-05649-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 Why do we need sex-balanced studies of autism? / Christine Wu NORDAHL in Autism Research, 16-9 (September 2023)
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Titre : Why do we need sex-balanced studies of autism? Type de document : Texte imprimé et/ou numérique Auteurs : Christine Wu NORDAHL, Auteur Article en page(s) : p.1662-1669 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Males are diagnosed with autism much more frequently than females, and most research study samples reflect this male predominance. The result is that autistic females are understudied. There is a critical need to increase our understanding of autistic females, both biologically and clinically. The only way to do this is to recruit sex-balanced cohorts in studies so that similarities and differences between males and females can be evaluated in all autism research studies. The purpose of this commentary is to (1) provide historical context about how females came to be under-represented in all research, not just in the field of autism and (2) learn from other areas of health and medicine about the potentially dire consequences of not studying both sexes, and (3) draw attention to the need to recruit sex-balanced cohorts in autism research, particularly in neuroimaging studies. En ligne : https://doi.org/10.1002/aur.2971 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510
in Autism Research > 16-9 (September 2023) . - p.1662-1669[article] Why do we need sex-balanced studies of autism? [Texte imprimé et/ou numérique] / Christine Wu NORDAHL, Auteur . - p.1662-1669.
Langues : Anglais (eng)
in Autism Research > 16-9 (September 2023) . - p.1662-1669
Index. décimale : PER Périodiques Résumé : Abstract Males are diagnosed with autism much more frequently than females, and most research study samples reflect this male predominance. The result is that autistic females are understudied. There is a critical need to increase our understanding of autistic females, both biologically and clinically. The only way to do this is to recruit sex-balanced cohorts in studies so that similarities and differences between males and females can be evaluated in all autism research studies. The purpose of this commentary is to (1) provide historical context about how females came to be under-represented in all research, not just in the field of autism and (2) learn from other areas of health and medicine about the potentially dire consequences of not studying both sexes, and (3) draw attention to the need to recruit sex-balanced cohorts in autism research, particularly in neuroimaging studies. En ligne : https://doi.org/10.1002/aur.2971 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510