Gestational Age in Autistic Children and Adolescents: Prevalence and Effects on Autism Phenotype / Miriam I. MARTINI in Journal of Autism and Developmental Disorders, 53-5 (May 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-5 (May 2023) . - p.1906-1914 Titre : Gestational Age in Autistic Children and Adolescents: Prevalence and Effects on Autism Phenotype Type de document : texte imprimé Auteurs : Miriam I. MARTINI, Auteur ; Inge MERKELBACH, Auteur ; Sander BEGEER, Auteur Article en page(s) : p.1906-1914 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Pre- and post-term children show increased autism risk. Little is known about gestational age (GA) prevalence among autistic children, and their respective autism phenotype. We compared prevalence of pre-, full- and post-term birth between a population-derived sample of N=606 (137 females, 22.61%) autistic children and adolescents (mean age=14.01, SD=3.63, range 3-24) from the Netherlands Autism Register, and matched controls from the Dutch birth register. Autism phenotype and comorbid symptoms were assessed with the AQ-short and SDQ questionnaires. Using logistic regression, we found higher prevalence of pre- and post-term birth among autistic individuals but no phenotypical differences across GA groups. Autism risk was particularly elevated for post-term children, highlighting the need for closer investigation of autism on the whole GA range. En ligne : https://doi.org/10.1007/s10803-022-05466-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500 [article] Gestational Age in Autistic Children and Adolescents: Prevalence and Effects on Autism Phenotype [texte imprimé] / Miriam I. MARTINI, Auteur ; Inge MERKELBACH, Auteur ; Sander BEGEER, Auteur . - p.1906-1914. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-5 (May 2023) . - p.1906-1914 Index. décimale : PER Périodiques Résumé : Pre- and post-term children show increased autism risk. Little is known about gestational age (GA) prevalence among autistic children, and their respective autism phenotype. We compared prevalence of pre-, full- and post-term birth between a population-derived sample of N=606 (137 females, 22.61%) autistic children and adolescents (mean age=14.01, SD=3.63, range 3-24) from the Netherlands Autism Register, and matched controls from the Dutch birth register. Autism phenotype and comorbid symptoms were assessed with the AQ-short and SDQ questionnaires. Using logistic regression, we found higher prevalence of pre- and post-term birth among autistic individuals but no phenotypical differences across GA groups. Autism risk was particularly elevated for post-term children, highlighting the need for closer investigation of autism on the whole GA range. En ligne : https://doi.org/10.1007/s10803-022-05466-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500

Sex differences in psychiatric diagnoses preceding autism diagnosis and their stability post autism diagnosis / Miriam I. MARTINI in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1170-1181 Titre : Sex differences in psychiatric diagnoses preceding autism diagnosis and their stability post autism diagnosis Type de document : texte imprimé Auteurs : Miriam I. MARTINI, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Agnieszka BUTWICKA, Auteur ; Ebba DU RIETZ, Auteur ; Aleksandra KANINA, Auteur ; Isabell BRIKELL, Auteur ; Zheng CHANG, Auteur ; Henrik LARSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur ; Francesca HAPPE, Auteur ; Mark J. TAYLOR, Auteur Article en page(s) : p.1170-1181 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  sex differences  psychiatric diagnoses  follow-up study Index. décimale : PER Périodiques Résumé : Background Autistic individuals often receive psychiatric diagnoses prior to their autism diagnosis. It remains unclear to what extent autistic females and males differ in their likelihood of receiving psychiatric diagnoses prior to their autism diagnosis and continue seeking care for them after an autism diagnosis. Methods In a nationwide cohort of all individuals born in Sweden 1990 2015 with a clinical autism diagnosis (N 72,331, nfemales 24,110), we used linear and logistic regression to estimate the association between sex and (a) psychiatric diagnoses before autism diagnosis, including time trends by autism diagnosis year (2010 2020), (b) autism diagnosis age in those with preceding diagnoses, (c) stability of preceding diagnoses (defined as continued care utilization indicated through diagnosis or medication in the 5 years following autism diagnosis). Results In total 54.2% of autistic females and 40.9% of autistic males received at least one preceding psychiatric diagnosis (most common: ADHD, anxiety, depression). Autistic females showed higher odds than males for most preceding psychiatric diagnoses (ORrange 1.29 [1.18, 1.41] 10.69 [8.06, 14.17]), except psychotic disorders (OR 0.91 [0.78, 1.06]) and ADHD (OR 0.69 [0.66, 0.71]). Sex differences in preceding diagnoses were persistent across different autism diagnosis years (2010 2020). For most conditions, females with a preceding diagnosis were diagnosed with autism later than males with the same condition. For both sexes, the stability of preceding diagnoses varied considerably (23.1% 88.9%) and was less than 50% for most diagnoses. Females showed a higher stability for anxiety, sleep disorders and self-harm (ORrange 1.45 [1.30, 1.62] 2.37 [1.93, 2.90]), and males for psychotic disorders (OR 0.60 [0.44, 0.81]). Conclusions Autistic females are more likely to be diagnosed with psychiatric conditions prior to an autism diagnosis and receive care for them post autism diagnosis. Our findings emphasize the variability of clinical presentation and importance of disentangling persistent support needs from overlapping diagnostic presentations, particularly in autistic females, to provide appropriate and timely care. En ligne : https://doi.org/10.1111/jcpp.14130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] Sex differences in psychiatric diagnoses preceding autism diagnosis and their stability post autism diagnosis [texte imprimé] / Miriam I. MARTINI, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Agnieszka BUTWICKA, Auteur ; Ebba DU RIETZ, Auteur ; Aleksandra KANINA, Auteur ; Isabell BRIKELL, Auteur ; Zheng CHANG, Auteur ; Henrik LARSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur ; Francesca HAPPE, Auteur ; Mark J. TAYLOR, Auteur . - p.1170-1181. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1170-1181 Mots-clés : Autism spectrum disorder  sex differences  psychiatric diagnoses  follow-up study Index. décimale : PER Périodiques Résumé : Background Autistic individuals often receive psychiatric diagnoses prior to their autism diagnosis. It remains unclear to what extent autistic females and males differ in their likelihood of receiving psychiatric diagnoses prior to their autism diagnosis and continue seeking care for them after an autism diagnosis. Methods In a nationwide cohort of all individuals born in Sweden 1990 2015 with a clinical autism diagnosis (N 72,331, nfemales 24,110), we used linear and logistic regression to estimate the association between sex and (a) psychiatric diagnoses before autism diagnosis, including time trends by autism diagnosis year (2010 2020), (b) autism diagnosis age in those with preceding diagnoses, (c) stability of preceding diagnoses (defined as continued care utilization indicated through diagnosis or medication in the 5 years following autism diagnosis). Results In total 54.2% of autistic females and 40.9% of autistic males received at least one preceding psychiatric diagnosis (most common: ADHD, anxiety, depression). Autistic females showed higher odds than males for most preceding psychiatric diagnoses (ORrange 1.29 [1.18, 1.41] 10.69 [8.06, 14.17]), except psychotic disorders (OR 0.91 [0.78, 1.06]) and ADHD (OR 0.69 [0.66, 0.71]). Sex differences in preceding diagnoses were persistent across different autism diagnosis years (2010 2020). For most conditions, females with a preceding diagnosis were diagnosed with autism later than males with the same condition. For both sexes, the stability of preceding diagnoses varied considerably (23.1% 88.9%) and was less than 50% for most diagnoses. Females showed a higher stability for anxiety, sleep disorders and self-harm (ORrange 1.45 [1.30, 1.62] 2.37 [1.93, 2.90]), and males for psychotic disorders (OR 0.60 [0.44, 0.81]). Conclusions Autistic females are more likely to be diagnosed with psychiatric conditions prior to an autism diagnosis and receive care for them post autism diagnosis. Our findings emphasize the variability of clinical presentation and importance of disentangling persistent support needs from overlapping diagnostic presentations, particularly in autistic females, to provide appropriate and timely care. En ligne : https://doi.org/10.1111/jcpp.14130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap / Georgina M. HOSANG in Journal of Child Psychology and Psychiatry, 67-5 (May 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-5 (May 2026) . - p.686-695 Titre : Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap Type de document : texte imprimé Auteurs : Georgina M. HOSANG, Auteur ; Miriam I. MARTINI, Auteur ; Angelica RONALD, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Paul LICHTENSTEIN, Auteur ; Mark J. TAYLOR, Auteur Article en page(s) : p.686-695 Langues : Anglais (eng) Mots-clés : Hypomania  psychiatric illnesses  neurodevelopmental conditions  twin study  genetic Index. décimale : PER Périodiques Résumé : Background Subclinical hypomanic symptoms are fairly common in the general population but are linked to psychiatric and neurodevelopmental conditions. However, the genetic and environmental origins of these associations are unclear. This twin study examined the phenotypic and aetiological associations between subclinical hypomania and psychiatric and neurodevelopmental diagnoses. Methods Participants were 4,932 twin pairs from the Child and Adolescent Twin Study in Sweden. Hypomanic symptoms were assessed using the parent-rated Mood Disorders Questionnaire when the twins were aged 18. Specialist diagnoses of 14 conditions and symptoms were ascertained from Swedish population registries. Phenotypic associations between hypomania and these conditions/symptoms were investigated, and their aetiological overlap was examined using the twin method. Results Subclinical hypomania was significantly associated with all 14 diagnoses. The highest odds were for psychotic disorders (odds ratio [OR]?=?1.48, 95% confidence intervals [CI]?=?1.33?1.64, p? En ligne : https://doi.org/10.1111/jcpp.70045 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586 [article] Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap [texte imprimé] / Georgina M. HOSANG, Auteur ; Miriam I. MARTINI, Auteur ; Angelica RONALD, Auteur ; Henrik LARSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Paul LICHTENSTEIN, Auteur ; Mark J. TAYLOR, Auteur . - p.686-695. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-5 (May 2026) . - p.686-695 Mots-clés : Hypomania  psychiatric illnesses  neurodevelopmental conditions  twin study  genetic Index. décimale : PER Périodiques Résumé : Background Subclinical hypomanic symptoms are fairly common in the general population but are linked to psychiatric and neurodevelopmental conditions. However, the genetic and environmental origins of these associations are unclear. This twin study examined the phenotypic and aetiological associations between subclinical hypomania and psychiatric and neurodevelopmental diagnoses. Methods Participants were 4,932 twin pairs from the Child and Adolescent Twin Study in Sweden. Hypomanic symptoms were assessed using the parent-rated Mood Disorders Questionnaire when the twins were aged 18. Specialist diagnoses of 14 conditions and symptoms were ascertained from Swedish population registries. Phenotypic associations between hypomania and these conditions/symptoms were investigated, and their aetiological overlap was examined using the twin method. Results Subclinical hypomania was significantly associated with all 14 diagnoses. The highest odds were for psychotic disorders (odds ratio [OR]?=?1.48, 95% confidence intervals [CI]?=?1.33?1.64, p? En ligne : https://doi.org/10.1111/jcpp.70045 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586

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