17 recherche sur le mot-clé 'genetic'

Twin Studies in Autism: What Might They Say About Genetic and Environmental Influences / George M. ANDERSON in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1526-1527 Titre : Twin Studies in Autism: What Might They Say About Genetic and Environmental Influences Type de document : Texte imprimé et/ou numérique Auteurs : George M. ANDERSON, Auteur Année de publication : 2012 Article en page(s) : p.1526-1527 Langues : Anglais (eng) Mots-clés : Autism  Risk  Twin  Monozygotic  Heritability  Genetic  Environmental Index. décimale : PER Périodiques Résumé : Genetic and epigenetic differences exist within monozygote twin-pairs and might be especially important in the expression of autism. Assuming phenotypic differences between monozygotic twins are due to environmental influences may lead to mistaken conclusions regarding the relative genetic and environmental contribution to autism risk. En ligne : http://dx.doi.org/10.1007/s10803-012-1552-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 [article] Twin Studies in Autism: What Might They Say About Genetic and Environmental Influences [Texte imprimé et/ou numérique] / George M. ANDERSON, Auteur . - 2012 . - p.1526-1527. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1526-1527 Mots-clés : Autism  Risk  Twin  Monozygotic  Heritability  Genetic  Environmental Index. décimale : PER Périodiques Résumé : Genetic and epigenetic differences exist within monozygote twin-pairs and might be especially important in the expression of autism. Assuming phenotypic differences between monozygotic twins are due to environmental influences may lead to mistaken conclusions regarding the relative genetic and environmental contribution to autism risk. En ligne : http://dx.doi.org/10.1007/s10803-012-1552-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166

Brief Report: Genetic Links Between Autism and Suicidal Behavior-A Preliminary Investigation / Emily DIBLASI in Journal of Autism and Developmental Disorders, 50-10 (October 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3525-3530 Titre : Brief Report: Genetic Links Between Autism and Suicidal Behavior-A Preliminary Investigation Type de document : Texte imprimé et/ou numérique Auteurs : Emily DIBLASI, Auteur ; Anne V. KIRBY, Auteur ; Eoin GAJ, Auteur ; Anna R. DOCHERTY, Auteur ; Brooks R. KEESHIN, Auteur ; Amanda V. BAKIAN, Auteur ; Hilary COON, Auteur Article en page(s) : p.3525-3530 Langues : Anglais (eng) Mots-clés : Autism  Gene set enrichment  Genetic  Suicide  publicly-available databases and existing published literature  no direct research  was conducted with human participants nor animals. No informed consent procedures  were used. Index. décimale : PER Périodiques Résumé : Evidence suggests there may be increased risk for suicidal behavior among individuals with autism spectrum disorder (ASD). An emerging body of research explores social factors that may contribute to increased risk, however little is known about the potential role of biological factors. The current project addresses this knowledge gap through a preliminary study of genes associated with both ASD and suicidal behavior. Gene set enrichment tests of eight genes strongly associated with both ASD and suicidal behavior revealed overrepresentation of nine biological processes, including cognition and synapse function, and 14 cellular components, including the neuron, the synapse, and the synaptic and postsynaptic membrane. These results can be used to inform future investigations of the biological underpinnings of suicidal behavior and ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04419-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Brief Report: Genetic Links Between Autism and Suicidal Behavior-A Preliminary Investigation [Texte imprimé et/ou numérique] / Emily DIBLASI, Auteur ; Anne V. KIRBY, Auteur ; Eoin GAJ, Auteur ; Anna R. DOCHERTY, Auteur ; Brooks R. KEESHIN, Auteur ; Amanda V. BAKIAN, Auteur ; Hilary COON, Auteur . - p.3525-3530. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3525-3530 Mots-clés : Autism  Gene set enrichment  Genetic  Suicide  publicly-available databases and existing published literature  no direct research  was conducted with human participants nor animals. No informed consent procedures  were used. Index. décimale : PER Périodiques Résumé : Evidence suggests there may be increased risk for suicidal behavior among individuals with autism spectrum disorder (ASD). An emerging body of research explores social factors that may contribute to increased risk, however little is known about the potential role of biological factors. The current project addresses this knowledge gap through a preliminary study of genes associated with both ASD and suicidal behavior. Gene set enrichment tests of eight genes strongly associated with both ASD and suicidal behavior revealed overrepresentation of nine biological processes, including cognition and synapse function, and 14 cellular components, including the neuron, the synapse, and the synaptic and postsynaptic membrane. These results can be used to inform future investigations of the biological underpinnings of suicidal behavior and ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04419-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Commentary: Genetic influences on adolescent attachment security: an empirical reminder of biology and the complexities of development – a reply to Rutter (2014) / Richard M. PASCO FEARON in Journal of Child Psychology and Psychiatry, 55-9 (September 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.1043-1046 Titre : Commentary: Genetic influences on adolescent attachment security: an empirical reminder of biology and the complexities of development – a reply to Rutter (2014) Type de document : Texte imprimé et/ou numérique Auteurs : Richard M. PASCO FEARON, Auteur ; Yael SHMUELI-GOETZ, Auteur ; Essi VIDING, Auteur ; Peter FONAGY, Auteur ; Robert PLOMIN, Auteur Article en page(s) : p.1043-1046 Langues : Anglais (eng) Mots-clés : Attachment security  adolescent  genetic  biological  environmental  influences  psychological development Index. décimale : PER Périodiques Résumé : We were delighted to learn that Michael Rutter had written a commentary (Rutter, 2014) on our article (Fearon, Shmueli-Goetz, Viding, Fonagy, Plomin, 2014). En ligne : http://dx.doi.org/10.1111/jcpp.12302 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Commentary: Genetic influences on adolescent attachment security: an empirical reminder of biology and the complexities of development – a reply to Rutter (2014) [Texte imprimé et/ou numérique] / Richard M. PASCO FEARON, Auteur ; Yael SHMUELI-GOETZ, Auteur ; Essi VIDING, Auteur ; Peter FONAGY, Auteur ; Robert PLOMIN, Auteur . - p.1043-1046. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.1043-1046 Mots-clés : Attachment security  adolescent  genetic  biological  environmental  influences  psychological development Index. décimale : PER Périodiques Résumé : We were delighted to learn that Michael Rutter had written a commentary (Rutter, 2014) on our article (Fearon, Shmueli-Goetz, Viding, Fonagy, Plomin, 2014). En ligne : http://dx.doi.org/10.1111/jcpp.12302 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Common genetic and nonshared environmental factors contribute to the association between socioemotional dispositions and the externalizing factor in children / Jeanette TAYLOR in Journal of Child Psychology and Psychiatry, 54-1 (January 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-1 (January 2013) . - 67-76 Titre : Common genetic and nonshared environmental factors contribute to the association between socioemotional dispositions and the externalizing factor in children Type de document : Texte imprimé et/ou numérique Auteurs : Jeanette TAYLOR, Auteur ; Nicholas P. ALLAN, Auteur ; Amy J. MIKOLAJEWSKI, Auteur ; Sara A. HART, Auteur Article en page(s) : 67-76 Langues : Anglais (eng) Mots-clés : Externalizing  genetic  temperament  dispositions; Index. décimale : PER Périodiques Résumé : Background: Childhood behavioral disorders including conduct disorder (CD), oppositional defiant disorder (ODD), and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Prior twin research shows that common sets of genetic and environmental factors are associated with these various disorders and they form a latent factor called Externalizing. The developmental propensity model posits that CD develops in part from socioemotional dispositions of Prosociality, Negative Emotionality, and Daring; and recent research has supported the expected genetic and environmental associations between these dispositions and CD. This study examined the developmental propensity model in relation to the broader Externalizing factor that represents the covariance among behavior disorders in children. Methods: Parents of 686 six- to twelve-year-old twin pairs rated them on symptoms of CD, ADHD, and ODD using the disruptive behavior disorder scale and on Prosociality, Negative Emotionality, and Daring using the Child and Adolescent Dispositions Scale. A latent factor multivariate Cholesky model was used with each disposition latent factor comprised of respective questionnaire items and the Externalizing factor comprised of symptom dimensions of CD, ADHD inattention, ADHD hyperactivity/impulsivity, and ODD. Results: Results supported the hypothesis that the socioemotional dispositions and the Externalizing factor have genetic factors in common, but there was not a single genetic factor associated with all of the constructs. As expected, nonshared environment factors were shared by the dispositions and Externalizing factor but, again, no single nonshared environmental factor was common to all constructs. A shared environmental factor was associated with both Negative Emotionality and Externalizing. Conclusions: The developmental propensity model was supported and appears to extend to the broader externalizing spectrum of childhood disorders. Socioemotional dispositions of prosociality, negative emotionality, and (to a lesser extent) daring may contribute to the covariation among behavioral disorders and perhaps to their comorbid expression through common sets of primarily genetic but also environmental factors. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02621.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186 [article] Common genetic and nonshared environmental factors contribute to the association between socioemotional dispositions and the externalizing factor in children [Texte imprimé et/ou numérique] / Jeanette TAYLOR, Auteur ; Nicholas P. ALLAN, Auteur ; Amy J. MIKOLAJEWSKI, Auteur ; Sara A. HART, Auteur . - 67-76. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-1 (January 2013) . - 67-76 Mots-clés : Externalizing  genetic  temperament  dispositions; Index. décimale : PER Périodiques Résumé : Background: Childhood behavioral disorders including conduct disorder (CD), oppositional defiant disorder (ODD), and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Prior twin research shows that common sets of genetic and environmental factors are associated with these various disorders and they form a latent factor called Externalizing. The developmental propensity model posits that CD develops in part from socioemotional dispositions of Prosociality, Negative Emotionality, and Daring; and recent research has supported the expected genetic and environmental associations between these dispositions and CD. This study examined the developmental propensity model in relation to the broader Externalizing factor that represents the covariance among behavior disorders in children. Methods: Parents of 686 six- to twelve-year-old twin pairs rated them on symptoms of CD, ADHD, and ODD using the disruptive behavior disorder scale and on Prosociality, Negative Emotionality, and Daring using the Child and Adolescent Dispositions Scale. A latent factor multivariate Cholesky model was used with each disposition latent factor comprised of respective questionnaire items and the Externalizing factor comprised of symptom dimensions of CD, ADHD inattention, ADHD hyperactivity/impulsivity, and ODD. Results: Results supported the hypothesis that the socioemotional dispositions and the Externalizing factor have genetic factors in common, but there was not a single genetic factor associated with all of the constructs. As expected, nonshared environment factors were shared by the dispositions and Externalizing factor but, again, no single nonshared environmental factor was common to all constructs. A shared environmental factor was associated with both Negative Emotionality and Externalizing. Conclusions: The developmental propensity model was supported and appears to extend to the broader externalizing spectrum of childhood disorders. Socioemotional dispositions of prosociality, negative emotionality, and (to a lesser extent) daring may contribute to the covariation among behavioral disorders and perhaps to their comorbid expression through common sets of primarily genetic but also environmental factors. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02621.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186

Developmental profiles of child behavior problems from 18 months to 8 years: The protective effects of structured parenting vary by genetic risk / Leslie D. LEVE in Development and Psychopathology, 34-5 (December 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-5 (December 2022) . - p.1716-1730 Titre : Developmental profiles of child behavior problems from 18 months to 8 years: The protective effects of structured parenting vary by genetic risk Type de document : Texte imprimé et/ou numérique Auteurs : Leslie D. LEVE, Auteur ; Daniel ANDERSON, Auteur ; Gordon T. HAROLD, Auteur ; Jenae M. NEIDERHISER, Auteur ; Misaki N. NATSUAKI, Auteur ; Daniel S. SHAW, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur Article en page(s) : p.1716-1730 Langues : Anglais (eng) Mots-clés : adoption  behavior problems  childhood  genetic  parenting Index. décimale : PER Périodiques Résumé : Some children are more affected by specific family environments than others, as a function of differences in their genetic make-up. However, longitudinal studies of genetic moderation of parenting effects during early childhood have not been conducted. We examined developmental profiles of child behavior problems between 18 months and age 8 in a longitudinal parent “offspring sample of 361 adopted children. In toddlerhood (18 months), observed structured parenting indexed parental guidance in service of task goals. Biological parent psychopathology served as an index of genetic influences on children’s behavior problems. Four profiles of child behavior problems were identified: low stable (11%), average stable (50%), higher stable (29%), and high increasing (11%). A multinominal logistic regression analysis indicated a genetically moderated effect of structured parenting, such that for children whose biological mother had higher psychopathology, the odds of the child being in the low stable group increased as structured parenting increased. Conversely, for children whose biological mother had lower psychopathology, the odds of being in the low stable group was reduced when structured parenting increased. Results suggest that increasing structured parenting is an effective strategy for children at higher genetic risk for psychopathology, but may be detrimental for those at lower genetic risk. En ligne : http://dx.doi.org/10.1017/S0954579422000839 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 [article] Developmental profiles of child behavior problems from 18 months to 8 years: The protective effects of structured parenting vary by genetic risk [Texte imprimé et/ou numérique] / Leslie D. LEVE, Auteur ; Daniel ANDERSON, Auteur ; Gordon T. HAROLD, Auteur ; Jenae M. NEIDERHISER, Auteur ; Misaki N. NATSUAKI, Auteur ; Daniel S. SHAW, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur . - p.1716-1730. Langues : Anglais (eng) in Development and Psychopathology > 34-5 (December 2022) . - p.1716-1730 Mots-clés : adoption  behavior problems  childhood  genetic  parenting Index. décimale : PER Périodiques Résumé : Some children are more affected by specific family environments than others, as a function of differences in their genetic make-up. However, longitudinal studies of genetic moderation of parenting effects during early childhood have not been conducted. We examined developmental profiles of child behavior problems between 18 months and age 8 in a longitudinal parent “offspring sample of 361 adopted children. In toddlerhood (18 months), observed structured parenting indexed parental guidance in service of task goals. Biological parent psychopathology served as an index of genetic influences on children’s behavior problems. Four profiles of child behavior problems were identified: low stable (11%), average stable (50%), higher stable (29%), and high increasing (11%). A multinominal logistic regression analysis indicated a genetically moderated effect of structured parenting, such that for children whose biological mother had higher psychopathology, the odds of the child being in the low stable group increased as structured parenting increased. Conversely, for children whose biological mother had lower psychopathology, the odds of being in the low stable group was reduced when structured parenting increased. Results suggest that increasing structured parenting is an effective strategy for children at higher genetic risk for psychopathology, but may be detrimental for those at lower genetic risk. En ligne : http://dx.doi.org/10.1017/S0954579422000839 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492

HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescents / L. R. STARR in Development and Psychopathology, 31-4 (October 2019)  

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Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses / Corinne M. SPENCER in Autism Research, 4-1 (February 2011)  

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Oppositional defiant disorder dimensions: genetic influences and risk for later psychopathology / Amy J. MIKOLAJEWSKI in Journal of Child Psychology and Psychiatry, 58-6 (June 2017)  

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Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis / Anneli ANDERSSON in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

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The contribution of epigenetics to understanding genetic factors in autism / Layla HALL in Autism, 18-8 (November 2014)  

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