Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents / Xin WANG in Journal of Autism and Developmental Disorders, 56-10 (October 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4001-4009 Titre : Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents Type de document : texte imprimé Auteurs : Xin WANG, Auteur ; Chunhua WANG, Auteur ; Lizi LIN, Auteur ; Wei BAO, Auteur ; Buyun LIU, Auteur ; Baihua LIN, Auteur ; Lijie ZHANG, Auteur ; Guifeng XU, Auteur Article en page(s) : p. 4001-4009 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with Down syndrome (DS) are more likely to be diagnosed with co-existing conditions, such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). However, the correlation has not been fully delineated to date. Our study aimed to examine the associations of DS with ASD and ADHD in children and adolescents using a national population-based database. In this cross-sectional study, we included a total of 214,300 children aged 3–17 years from the National Health Interview Survey. Physician-diagnosed DS, ASD and ADHD were reported during an in-person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratios (ORs) of ASD and ADHD, along with 95% confidence intervals (CIs). Among the 214,300 children, 329 were identified as having DS. Among those, 21 children were diagnosed with ASD, 48 with ADHD, and 6 exhibited co-existing ASD and ADHD. After adjusting for demographic factors, compared to those without DS, the ORs of ASD, ADHD and the co-occurrence of ASD and ADHD in children with DS were 5.40 (95% CI: 3.04–9.59), 1.72 (95% CI: 1.17–2.53), and 3.45(95% CI:1.29–9.20), respectively. Stratified analysis revealed that significant associations of DS with ASD and ADHD were detected for both male and female, but an interaction effect was only observed between sex and ASD (P < 0.001). Our study confirmed that children with DS are more likely to have comorbidities of ASD and ADHD than the general population, and these comorbidities may vary by sex. En ligne : https://doi.org/10.1007/s10803-025-06834-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593 [article] Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents [texte imprimé] / Xin WANG, Auteur ; Chunhua WANG, Auteur ; Lizi LIN, Auteur ; Wei BAO, Auteur ; Buyun LIU, Auteur ; Baihua LIN, Auteur ; Lijie ZHANG, Auteur ; Guifeng XU, Auteur . - p. 4001-4009. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4001-4009 Index. décimale : PER Périodiques Résumé : Children with Down syndrome (DS) are more likely to be diagnosed with co-existing conditions, such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). However, the correlation has not been fully delineated to date. Our study aimed to examine the associations of DS with ASD and ADHD in children and adolescents using a national population-based database. In this cross-sectional study, we included a total of 214,300 children aged 3–17 years from the National Health Interview Survey. Physician-diagnosed DS, ASD and ADHD were reported during an in-person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratios (ORs) of ASD and ADHD, along with 95% confidence intervals (CIs). Among the 214,300 children, 329 were identified as having DS. Among those, 21 children were diagnosed with ASD, 48 with ADHD, and 6 exhibited co-existing ASD and ADHD. After adjusting for demographic factors, compared to those without DS, the ORs of ASD, ADHD and the co-occurrence of ASD and ADHD in children with DS were 5.40 (95% CI: 3.04–9.59), 1.72 (95% CI: 1.17–2.53), and 3.45(95% CI:1.29–9.20), respectively. Stratified analysis revealed that significant associations of DS with ASD and ADHD were detected for both male and female, but an interaction effect was only observed between sex and ASD (P < 0.001). Our study confirmed that children with DS are more likely to have comorbidities of ASD and ADHD than the general population, and these comorbidities may vary by sex. En ligne : https://doi.org/10.1007/s10803-025-06834-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593

Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 – 2021 National Survey of Children’s Health / Qianyi XIE in Journal of Autism and Developmental Disorders, 56-10 (October 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4010-4024 Titre : Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 – 2021 National Survey of Children’s Health Type de document : texte imprimé Auteurs : Qianyi XIE, Auteur ; Ning PAN, Auteur ; Xiaoxuan OU, Auteur ; Shuli SHEN, Auteur ; Jin JING, Auteur ; Xuchu WENG, Auteur ; Lei SHI, Auteur ; Lizi LIN, Auteur ; Jiaze YANG, Auteur ; Xiangpeng LI, Auteur ; Kai ZHANG, Auteur ; Fangfang CHEN, Auteur ; Yujie WANG, Auteur ; Jinqing WU, Auteur ; Xin WANG, Auteur Article en page(s) : p. 4010-4024 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) have long been reported to exhibit atypical pain experiences. Chronic physical pain is a significant comorbidity in ASD, leading to substantial burdens on daily functioning and quality of life. This study aims to examine the potential associations between ASD and chronic physical pain, including its specific types. The study used data on chronic physical pain and headaches from the 2016 – 2021 National Survey of Children’s Health. Participants were children aged 3 to 17 years old. Generalized linear models were used to estimate the associations between ASD and pain-related indicators (e.g., chronic physical pain, headaches, and other back or body pain). The study included 177,539 children, of whom 5311 had a current ASD diagnosis. Among children with current ASD, 14.41% experienced chronic physical pain, with 4.86% reporting headaches and 9.56% reporting other back or body pain. Compared to those without, children with current ASD had higher odds of chronic physical pain [odds ratio (OR) = 1.76, 95% confidence interval (CI): 1.40 – 2.21]. Notably, the odds of headaches (OR = 1.78, 95% CI: 1.33 – 2.38) were higher than the odds of other back or body pain (OR = 1.62, 95% CI: 1.20 – 2.19). Children with current ASD were more likely to experience chronic physical pain than those without. This trend is more pronounced in headaches compared to other back or body pain. Our findings highlight the importance of prioritizing pain management in children with ASD through thorough physical assessments. En ligne : https://doi.org/10.1007/s10803-025-06846-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593 [article] Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 – 2021 National Survey of Children’s Health [texte imprimé] / Qianyi XIE, Auteur ; Ning PAN, Auteur ; Xiaoxuan OU, Auteur ; Shuli SHEN, Auteur ; Jin JING, Auteur ; Xuchu WENG, Auteur ; Lei SHI, Auteur ; Lizi LIN, Auteur ; Jiaze YANG, Auteur ; Xiangpeng LI, Auteur ; Kai ZHANG, Auteur ; Fangfang CHEN, Auteur ; Yujie WANG, Auteur ; Jinqing WU, Auteur ; Xin WANG, Auteur . - p. 4010-4024. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-10 (October 2026) . - p. 4010-4024 Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) have long been reported to exhibit atypical pain experiences. Chronic physical pain is a significant comorbidity in ASD, leading to substantial burdens on daily functioning and quality of life. This study aims to examine the potential associations between ASD and chronic physical pain, including its specific types. The study used data on chronic physical pain and headaches from the 2016 – 2021 National Survey of Children’s Health. Participants were children aged 3 to 17 years old. Generalized linear models were used to estimate the associations between ASD and pain-related indicators (e.g., chronic physical pain, headaches, and other back or body pain). The study included 177,539 children, of whom 5311 had a current ASD diagnosis. Among children with current ASD, 14.41% experienced chronic physical pain, with 4.86% reporting headaches and 9.56% reporting other back or body pain. Compared to those without, children with current ASD had higher odds of chronic physical pain [odds ratio (OR) = 1.76, 95% confidence interval (CI): 1.40 – 2.21]. Notably, the odds of headaches (OR = 1.78, 95% CI: 1.33 – 2.38) were higher than the odds of other back or body pain (OR = 1.62, 95% CI: 1.20 – 2.19). Children with current ASD were more likely to experience chronic physical pain than those without. This trend is more pronounced in headaches compared to other back or body pain. Our findings highlight the importance of prioritizing pain management in children with ASD through thorough physical assessments. En ligne : https://doi.org/10.1007/s10803-025-06846-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=593

Gender Difference in the Association Between Executive Function and Autistic Traits in Typically Developing Children / Meixia DAI in Journal of Autism and Developmental Disorders, 49-3 (March 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.1182-1192 Titre : Gender Difference in the Association Between Executive Function and Autistic Traits in Typically Developing Children Type de document : texte imprimé Auteurs : Meixia DAI, Auteur ; Lizi LIN, Auteur ; Jingjing LIANG, Auteur ; Ziqi WANG, Auteur ; Jin JING, Auteur Article en page(s) : p.1182-1192 Langues : Anglais (eng) Mots-clés : Autistic trait  Children  Executive functions  Gender difference Index. décimale : PER Périodiques Résumé : Autistic traits and executive function (EF) were assessed in 413 typically developing children aged 6-9 years. The children were divided into the high- autistic-trait (HAT) and low-autistic-trait (LAT) groups based on their total autistic traits. Results suggested that there were gender differences in specific autistic traits in children with LAT. There were gender-specific associations between EF and autistic traits in children with HAT: the set shifting of EF predicted difficulties in social awareness in boys; whereas all the EF components predicted difficulties in social communication and social cognition in girls. These findings may have implications for developing customized interventions that are targeted at specific autistic deficits in males and females. En ligne : http://dx.doi.org/10.1007/s10803-018-3813-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Gender Difference in the Association Between Executive Function and Autistic Traits in Typically Developing Children [texte imprimé] / Meixia DAI, Auteur ; Lizi LIN, Auteur ; Jingjing LIANG, Auteur ; Ziqi WANG, Auteur ; Jin JING, Auteur . - p.1182-1192. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.1182-1192 Mots-clés : Autistic trait  Children  Executive functions  Gender difference Index. décimale : PER Périodiques Résumé : Autistic traits and executive function (EF) were assessed in 413 typically developing children aged 6-9 years. The children were divided into the high- autistic-trait (HAT) and low-autistic-trait (LAT) groups based on their total autistic traits. Results suggested that there were gender differences in specific autistic traits in children with LAT. There were gender-specific associations between EF and autistic traits in children with HAT: the set shifting of EF predicted difficulties in social awareness in boys; whereas all the EF components predicted difficulties in social communication and social cognition in girls. These findings may have implications for developing customized interventions that are targeted at specific autistic deficits in males and females. En ligne : http://dx.doi.org/10.1007/s10803-018-3813-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

Prevalence of Autism Spectrum Disorder in the United States is Stable in the COVID-19 Era / Xin WANG in Journal of Autism and Developmental Disorders, 53-8 (August 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3309-3312 Titre : Prevalence of Autism Spectrum Disorder in the United States is Stable in the COVID-19 Era Type de document : texte imprimé Auteurs : Xin WANG, Auteur ; Xuchu WENG, Auteur ; Ning PAN, Auteur ; Xiuhong LI, Auteur ; Lizi LIN, Auteur ; Jin JING, Auteur Article en page(s) : p.3309-3312 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Although the United States (US) have been monitoring the autism spectrum disorder (ASD) prevalence, whether the prevalence has continued to increase, decrease, fluctuate or reached a stable level remained unclear during the COVID-19 pandemic. We have requested the 2016-2021 National Survey of Children s Health (NSCH) data in the United States to estimate weighted ASD prevalence and assess linearity/nonlinearity in the time trend. We did not observe linear or nonlinear trends of the ASD prevalence during the 2016-2021 periods. The current ASD prevalence experienced a 0.3% drop from 2019 to 2020 but a 0.3% uptick in 2021, suggesting a stable trend during the COVID-19 pandemic. Our findings shed lights on the need for the modified strategy of monitor ASD prevalence during the COVID-19 era. En ligne : https://doi.org/10.1007/s10803-023-05915-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508 [article] Prevalence of Autism Spectrum Disorder in the United States is Stable in the COVID-19 Era [texte imprimé] / Xin WANG, Auteur ; Xuchu WENG, Auteur ; Ning PAN, Auteur ; Xiuhong LI, Auteur ; Lizi LIN, Auteur ; Jin JING, Auteur . - p.3309-3312. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3309-3312 Index. décimale : PER Périodiques Résumé : Although the United States (US) have been monitoring the autism spectrum disorder (ASD) prevalence, whether the prevalence has continued to increase, decrease, fluctuate or reached a stable level remained unclear during the COVID-19 pandemic. We have requested the 2016-2021 National Survey of Children s Health (NSCH) data in the United States to estimate weighted ASD prevalence and assess linearity/nonlinearity in the time trend. We did not observe linear or nonlinear trends of the ASD prevalence during the 2016-2021 periods. The current ASD prevalence experienced a 0.3% drop from 2019 to 2020 but a 0.3% uptick in 2021, suggesting a stable trend during the COVID-19 pandemic. Our findings shed lights on the need for the modified strategy of monitor ASD prevalence during the COVID-19 era. En ligne : https://doi.org/10.1007/s10803-023-05915-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508

Psychometric properties of the chinese version of autism spectrum quotient-children's version: A sex-specific analysis / Fan SUN in Autism Research, 12-2 (February 2019)  

Public ISBD [article]  inAutism Research > 12-2 (February 2019) . - p.303-315 Titre : Psychometric properties of the chinese version of autism spectrum quotient-children's version: A sex-specific analysis Type de document : texte imprimé Auteurs : Fan SUN, Auteur ; Meixia DAI, Auteur ; Lizi LIN, Auteur ; Xin SUN, Auteur ; Aja Louise MURRAY, Auteur ; Bonnie AUYEUNG, Auteur ; Jin JING, Auteur Article en page(s) : p.303-315 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  autism-spectrum quotient  autistic traits  children  sex differences Index. décimale : PER Périodiques Résumé : A Simplified Chinese translation of the Autism Spectrum Quotient-Children's Version (AQ-C) is needed for research in mainland China. Autism Spectrum Disorder (ASD) is a condition that differs in presentation and prevalence by sex. Thus, evaluating the psychometric validity of the AQ-C in males and females is an important step in its validation. The present study aims to develop a Chinese translation of the parent-report AQ-C, and test its psychometric properties among Mandarin Chinese speaking boys and girls. A total of 1,020 non-clinical children and 134 children with ASD were assessed. Factor analyses were performed for the whole sample, as well as for girls and boys separately. A 30-item, 5-factor model (the Chinese AQ-C) showed adequate goodness of fit (root mean square error of approximation [RMSEA] = 0.037; comparative fit index [CFI] = 0.907; Tucker-Lewis index [TLI] = 0.901) for the whole sample. According to parents' reports, non-clinical boys had significantly higher scores than non-clinical girls on the Chinese AQ-C. Sex-specific factor structures were identified resulting in a 4-factor model with 32 items for girls (the Chinese AQ-Girls), and a 4-factor model with 34 items for boys (the Chinese AQ-Boys). The cut-off scores of the Chinese AQ-C, AQ-Girls, and AQ-Boys were 44.5, 42.5, and 46.5, respectively. These three Chinese versions of the AQ-C all showed satisfactory internal consistency (alpha = 0.786-0.840) and concurrent validity with the Social Responsiveness Scale (r = 0.789-0.814) for the total scale. Differences have been found in the sex-specific factor structures of the AQ-C which would be more reliable to use for future research when measuring autistic traits in the general population. Autism Res 2019, 12: 303-315 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study developed Chinese versions of the Autism Spectrum Quotient-Children's Version (AQ-C) in Chinese boys and girls together and separately. The AQ-C showed good psychometric properties in boys and girls together and separately. There were differences in sex-specific factor structures of the AQ-C. These results suggest that the sex-specific Chinese versions of the AQ-C provide reliable and valid measurement of autistic traits. En ligne : http://dx.doi.org/10.1002/aur.2053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383 [article] Psychometric properties of the chinese version of autism spectrum quotient-children's version: A sex-specific analysis [texte imprimé] / Fan SUN, Auteur ; Meixia DAI, Auteur ; Lizi LIN, Auteur ; Xin SUN, Auteur ; Aja Louise MURRAY, Auteur ; Bonnie AUYEUNG, Auteur ; Jin JING, Auteur . - p.303-315. Langues : Anglais (eng) in Autism Research > 12-2 (February 2019) . - p.303-315 Mots-clés : autism spectrum disorder  autism-spectrum quotient  autistic traits  children  sex differences Index. décimale : PER Périodiques Résumé : A Simplified Chinese translation of the Autism Spectrum Quotient-Children's Version (AQ-C) is needed for research in mainland China. Autism Spectrum Disorder (ASD) is a condition that differs in presentation and prevalence by sex. Thus, evaluating the psychometric validity of the AQ-C in males and females is an important step in its validation. The present study aims to develop a Chinese translation of the parent-report AQ-C, and test its psychometric properties among Mandarin Chinese speaking boys and girls. A total of 1,020 non-clinical children and 134 children with ASD were assessed. Factor analyses were performed for the whole sample, as well as for girls and boys separately. A 30-item, 5-factor model (the Chinese AQ-C) showed adequate goodness of fit (root mean square error of approximation [RMSEA] = 0.037; comparative fit index [CFI] = 0.907; Tucker-Lewis index [TLI] = 0.901) for the whole sample. According to parents' reports, non-clinical boys had significantly higher scores than non-clinical girls on the Chinese AQ-C. Sex-specific factor structures were identified resulting in a 4-factor model with 32 items for girls (the Chinese AQ-Girls), and a 4-factor model with 34 items for boys (the Chinese AQ-Boys). The cut-off scores of the Chinese AQ-C, AQ-Girls, and AQ-Boys were 44.5, 42.5, and 46.5, respectively. These three Chinese versions of the AQ-C all showed satisfactory internal consistency (alpha = 0.786-0.840) and concurrent validity with the Social Responsiveness Scale (r = 0.789-0.814) for the total scale. Differences have been found in the sex-specific factor structures of the AQ-C which would be more reliable to use for future research when measuring autistic traits in the general population. Autism Res 2019, 12: 303-315 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study developed Chinese versions of the Autism Spectrum Quotient-Children's Version (AQ-C) in Chinese boys and girls together and separately. The AQ-C showed good psychometric properties in boys and girls together and separately. There were differences in sex-specific factor structures of the AQ-C. These results suggest that the sex-specific Chinese versions of the AQ-C provide reliable and valid measurement of autistic traits. En ligne : http://dx.doi.org/10.1002/aur.2053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383

Socioeconomic factors and autism among 16- to 30-month-old children: Evidence from a national survey of China / Muqing CAO in Autism, 27-5 (July 2023)  

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