Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people / Patrick SMITH in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1117-1128 Titre : Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people Type de document : texte imprimé Auteurs : Patrick SMITH, Auteur ; Anke EHLERS, Auteur ; Ewan CARR, Auteur ; David M. CLARK, Auteur ; Tim DALGLEISH, Auteur ; Gordon FORBES, Auteur ; Kimberley GOLDSMITH, Auteur ; Helena GRIFFITHS, Auteur ; Monica GUPTA, Auteur ; Dorothy KING, Auteur ; Sarah MILES, Auteur ; Dominic T. PLANT, Auteur ; Anne SMITH, Auteur ; Jess STEWARD, Auteur ; William YULE, Auteur ; Richard MEISER-STEDMAN, Auteur Article en page(s) : p.1117-1128 Langues : Anglais (eng) Mots-clés : Post-traumatic stress disorder  adolescence  cognitive therapy  E-health  Randomised Controlled Trial Index. décimale : PER Périodiques Résumé : Background Effective face-to-face treatments for Post-Traumatic Stress Disorder (PTSD) are available, but most young people with PTSD do not receive effective treatment. Therapist-supported online Cognitive Therapy has the potential to improve accessibility of effective treatment. This early-stage trial gathered data on the feasibility, acceptability, and initial signal of clinical efficacy of a novel online Cognitive Therapy program for young people with PTSD. Methods A two-arm, parallel-groups, single-blind, early-stage feasibility RCT compared online Cognitive Therapy to a waitlList condition. Participants were N 31 adolescents (12 17 years-old) with a diagnosis of PTSD, randomised in a 1:1 ratio using minimisation. Thresholds for progression to a larger trial were set a priori for recruitment rate, data completeness, and the initial signal of clinical efficacy. The primary clinical outcome was PTSD diagnosis at 16 weeks post-randomisation. Secondary clinical outcomes were continuous measures of PTSD, depression, and anxiety at 16 weeks; and at 38 weeks in the online Cognitive Therapy arm. Results All pre-determined feasibility thresholds for progression to a larger trial were met. We recruited to target at a rate of 1 2 participants/month. No patient dropped out of therapy; 94% of all participants were retained at 16 weeks. At 16-weeks, the intention-to-treat (ITT) effect adjusted odds ratio was 0.20 (95% CI, 0.02, 1.42), indicating that the odds of meeting PTSD caseness after online therapy were 80% lower than after the waitlist (10/16 participants met PTSD caseness after therapy compared to 11/13 after WL). Effect-size estimates for all secondary clinical outcomes were large-moderate; improvements were sustained 38 weeks after online Cognitive Therapy. Conclusions Therapist-supported online Cognitive Therapy for PTSD is acceptable to young people and has potential for meaningful and sustained clinical effects. A larger trial appears feasible to deliver. Further work is needed to refine the intervention and its delivery and to evaluate it in a larger confirmatory trial. En ligne : https://doi.org/10.1111/jcpp.14124 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=564 [article] Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people [texte imprimé] / Patrick SMITH, Auteur ; Anke EHLERS, Auteur ; Ewan CARR, Auteur ; David M. CLARK, Auteur ; Tim DALGLEISH, Auteur ; Gordon FORBES, Auteur ; Kimberley GOLDSMITH, Auteur ; Helena GRIFFITHS, Auteur ; Monica GUPTA, Auteur ; Dorothy KING, Auteur ; Sarah MILES, Auteur ; Dominic T. PLANT, Auteur ; Anne SMITH, Auteur ; Jess STEWARD, Auteur ; William YULE, Auteur ; Richard MEISER-STEDMAN, Auteur . - p.1117-1128. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1117-1128 Mots-clés : Post-traumatic stress disorder  adolescence  cognitive therapy  E-health  Randomised Controlled Trial Index. décimale : PER Périodiques Résumé : Background Effective face-to-face treatments for Post-Traumatic Stress Disorder (PTSD) are available, but most young people with PTSD do not receive effective treatment. Therapist-supported online Cognitive Therapy has the potential to improve accessibility of effective treatment. This early-stage trial gathered data on the feasibility, acceptability, and initial signal of clinical efficacy of a novel online Cognitive Therapy program for young people with PTSD. Methods A two-arm, parallel-groups, single-blind, early-stage feasibility RCT compared online Cognitive Therapy to a waitlList condition. Participants were N 31 adolescents (12 17 years-old) with a diagnosis of PTSD, randomised in a 1:1 ratio using minimisation. Thresholds for progression to a larger trial were set a priori for recruitment rate, data completeness, and the initial signal of clinical efficacy. The primary clinical outcome was PTSD diagnosis at 16 weeks post-randomisation. Secondary clinical outcomes were continuous measures of PTSD, depression, and anxiety at 16 weeks; and at 38 weeks in the online Cognitive Therapy arm. Results All pre-determined feasibility thresholds for progression to a larger trial were met. We recruited to target at a rate of 1 2 participants/month. No patient dropped out of therapy; 94% of all participants were retained at 16 weeks. At 16-weeks, the intention-to-treat (ITT) effect adjusted odds ratio was 0.20 (95% CI, 0.02, 1.42), indicating that the odds of meeting PTSD caseness after online therapy were 80% lower than after the waitlist (10/16 participants met PTSD caseness after therapy compared to 11/13 after WL). Effect-size estimates for all secondary clinical outcomes were large-moderate; improvements were sustained 38 weeks after online Cognitive Therapy. Conclusions Therapist-supported online Cognitive Therapy for PTSD is acceptable to young people and has potential for meaningful and sustained clinical effects. A larger trial appears feasible to deliver. Further work is needed to refine the intervention and its delivery and to evaluate it in a larger confirmatory trial. En ligne : https://doi.org/10.1111/jcpp.14124 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=564

Parent-Child Interaction Synchrony for Infants At-Risk for Autism Spectrum Disorder / Amanda Mossman STEINER in Journal of Autism and Developmental Disorders, 48-10 (October 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-10 (October 2018) . - p.3562-3572 Titre : Parent-Child Interaction Synchrony for Infants At-Risk for Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Amanda Mossman STEINER, Auteur ; Grace W. GENGOUX, Auteur ; Anne SMITH, Auteur ; Katarzyna CHAWARSKA, Auteur Article en page(s) : p.3562-3572 Langues : Anglais (eng) Mots-clés : Autism  Infant siblings  Parent-child interaction  Synchrony Index. décimale : PER Périodiques Résumé : This study investigated interactions between parents and 12-month-old infants at high (HR-SIBS; n = 27) and low (LR-SIBS; n = 14) familial risk for autism spectrum disorder (ASD). The contributions of parental variables, as well as child's autism symptom severity and verbal skills, to the parent interaction style were examined. Parents of HR-SIBS exhibited a higher level of synchronous-demanding behaviors, which was associated with parental report of atypical mood in the infant, but not with autism symptom severity, verbal skills, or parental depressive symptoms. These preliminary findings suggest a need for further investigation into HR-SIBS' emotional development and parental perception of that development, as these factors may shape parent-child interaction and influence the effectiveness of parent-assisted early intervention programs. En ligne : http://dx.doi.org/10.1007/s10803-018-3624-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Parent-Child Interaction Synchrony for Infants At-Risk for Autism Spectrum Disorder [texte imprimé] / Amanda Mossman STEINER, Auteur ; Grace W. GENGOUX, Auteur ; Anne SMITH, Auteur ; Katarzyna CHAWARSKA, Auteur . - p.3562-3572. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-10 (October 2018) . - p.3562-3572 Mots-clés : Autism  Infant siblings  Parent-child interaction  Synchrony Index. décimale : PER Périodiques Résumé : This study investigated interactions between parents and 12-month-old infants at high (HR-SIBS; n = 27) and low (LR-SIBS; n = 14) familial risk for autism spectrum disorder (ASD). The contributions of parental variables, as well as child's autism symptom severity and verbal skills, to the parent interaction style were examined. Parents of HR-SIBS exhibited a higher level of synchronous-demanding behaviors, which was associated with parental report of atypical mood in the infant, but not with autism symptom severity, verbal skills, or parental depressive symptoms. These preliminary findings suggest a need for further investigation into HR-SIBS' emotional development and parental perception of that development, as these factors may shape parent-child interaction and influence the effectiveness of parent-assisted early intervention programs. En ligne : http://dx.doi.org/10.1007/s10803-018-3624-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

Speech motor planning and execution deficits in early childhood stuttering / Bridget WALSH in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.27 Titre : Speech motor planning and execution deficits in early childhood stuttering Type de document : texte imprimé Auteurs : Bridget WALSH, Auteur ; Kathleen Marie METTEL, Auteur ; Anne SMITH, Auteur Article en page(s) : p.27 Langues : Anglais (eng) Mots-clés : Preschool children  Sex differences  Speech kinematics  Speech motor control  Speech production  Stuttering Index. décimale : PER Périodiques Résumé : BACKGROUND: Five to eight percent of preschool children develop stuttering, a speech disorder with clearly observable, hallmark symptoms: sound repetitions, prolongations, and blocks. While the speech motor processes underlying stuttering have been widely documented in adults, few studies to date have assessed the speech motor dynamics of stuttering near its onset. We assessed fundamental characteristics of speech movements in preschool children who stutter and their fluent peers to determine if atypical speech motor characteristics described for adults are early features of the disorder or arise later in the development of chronic stuttering. METHODS: Orofacial movement data were recorded from 58 children who stutter and 43 children who do not stutter aged 4;0 to 5;11 (years; months) in a sentence production task. For single speech movements and multiple speech movement sequences, we computed displacement amplitude, velocity, and duration. For the phrase level movement sequence, we computed an index of articulation coordination consistency for repeated productions of the sentence. RESULTS: Boys who stutter, but not girls, produced speech with reduced amplitudes and velocities of articulatory movement. All children produced speech with similar durations. Boys, particularly the boys who stuttered, had more variable patterns of articulatory coordination compared to girls. CONCLUSIONS: This study is the first to demonstrate sex-specific differences in speech motor control processes between preschool boys and girls who are stuttering. The sex-specific lag in speech motor development in many boys who stutter likely has significant implications for the dramatically different recovery rates between male and female preschoolers who stutter. Further, our findings document that atypical speech motor development is an early feature of stuttering. En ligne : http://dx.doi.org/10.1186/s11689-015-9123-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348 [article] Speech motor planning and execution deficits in early childhood stuttering [texte imprimé] / Bridget WALSH, Auteur ; Kathleen Marie METTEL, Auteur ; Anne SMITH, Auteur . - p.27. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.27 Mots-clés : Preschool children  Sex differences  Speech kinematics  Speech motor control  Speech production  Stuttering Index. décimale : PER Périodiques Résumé : BACKGROUND: Five to eight percent of preschool children develop stuttering, a speech disorder with clearly observable, hallmark symptoms: sound repetitions, prolongations, and blocks. While the speech motor processes underlying stuttering have been widely documented in adults, few studies to date have assessed the speech motor dynamics of stuttering near its onset. We assessed fundamental characteristics of speech movements in preschool children who stutter and their fluent peers to determine if atypical speech motor characteristics described for adults are early features of the disorder or arise later in the development of chronic stuttering. METHODS: Orofacial movement data were recorded from 58 children who stutter and 43 children who do not stutter aged 4;0 to 5;11 (years; months) in a sentence production task. For single speech movements and multiple speech movement sequences, we computed displacement amplitude, velocity, and duration. For the phrase level movement sequence, we computed an index of articulation coordination consistency for repeated productions of the sentence. RESULTS: Boys who stutter, but not girls, produced speech with reduced amplitudes and velocities of articulatory movement. All children produced speech with similar durations. Boys, particularly the boys who stuttered, had more variable patterns of articulatory coordination compared to girls. CONCLUSIONS: This study is the first to demonstrate sex-specific differences in speech motor control processes between preschool boys and girls who are stuttering. The sex-specific lag in speech motor development in many boys who stutter likely has significant implications for the dramatically different recovery rates between male and female preschoolers who stutter. Further, our findings document that atypical speech motor development is an early feature of stuttering. En ligne : http://dx.doi.org/10.1186/s11689-015-9123-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348

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