Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders / Roumen N. NIKOLOV in Journal of Autism and Developmental Disorders, 39-3 (March 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-3 (March 2009) . - p.405-413 Titre : Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders Type de document : texte imprimé Auteurs : Roumen N. NIKOLOV, Auteur ; Lawrence SCAHILL, Auteur ; Bhavik SHAH, Auteur ; Maria RODOWSKI, Auteur ; Craig ERICKSON, Auteur ; Jelle LETTINGA, Auteur ; Karen E. BEARSS, Auteur ; David J. POSEY, Auteur ; Louise RITZ, Auteur ; Elaine TIERNEY, Auteur ; Christopher J. MCDOUGLE, Auteur ; Michael G. AMAN, Auteur ; Benedetto VITIELLO, Auteur ; L. Eugene ARNOLD, Auteur ; James T. MCCRACKEN, Auteur Année de publication : 2009 Article en page(s) : p.405-413 Langues : Anglais (eng) Mots-clés : Autism Chronic-gastrointestinal-problems Pervasive-developmental-disorders Index. décimale : PER Périodiques Résumé : Objective To evaluate gastrointestinal (GI) problems in a large, well-characterized sample of children with pervasive developmental disorders (PDDs). Methods One hundred seventy two children entering one of two trials conducted by the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network were assessed comprehensively prior to starting treatment and classified with regard to GI symptoms. Results Thirty nine (22.7%) were positive for GI problems, primarily constipation and diarrhea. Those with GI problems were no different from subjects without GI problems in demographic characteristics, measures of adaptive functioning, or autism symptom severity. Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment. En ligne : http://dx.doi.org/10.1007/s10803-008-0637-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders [texte imprimé] / Roumen N. NIKOLOV, Auteur ; Lawrence SCAHILL, Auteur ; Bhavik SHAH, Auteur ; Maria RODOWSKI, Auteur ; Craig ERICKSON, Auteur ; Jelle LETTINGA, Auteur ; Karen E. BEARSS, Auteur ; David J. POSEY, Auteur ; Louise RITZ, Auteur ; Elaine TIERNEY, Auteur ; Christopher J. MCDOUGLE, Auteur ; Michael G. AMAN, Auteur ; Benedetto VITIELLO, Auteur ; L. Eugene ARNOLD, Auteur ; James T. MCCRACKEN, Auteur . - 2009 . - p.405-413. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-3 (March 2009) . - p.405-413 Mots-clés : Autism Chronic-gastrointestinal-problems Pervasive-developmental-disorders Index. décimale : PER Périodiques Résumé : Objective To evaluate gastrointestinal (GI) problems in a large, well-characterized sample of children with pervasive developmental disorders (PDDs). Methods One hundred seventy two children entering one of two trials conducted by the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network were assessed comprehensively prior to starting treatment and classified with regard to GI symptoms. Results Thirty nine (22.7%) were positive for GI problems, primarily constipation and diarrhea. Those with GI problems were no different from subjects without GI problems in demographic characteristics, measures of adaptive functioning, or autism symptom severity. Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment. En ligne : http://dx.doi.org/10.1007/s10803-008-0637-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

Psychiatric disorders in adolescents and young adults with Down syndrome and other intellectual disabilities / Elisabeth M. DYKENS in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.9 Titre : Psychiatric disorders in adolescents and young adults with Down syndrome and other intellectual disabilities Type de document : texte imprimé Auteurs : Elisabeth M. DYKENS, Auteur ; Bhavik SHAH, Auteur ; Bruce DAVIS, Auteur ; Cynthia BAKER, Auteur ; Taylor FIFE, Auteur ; Jeri FITZPATRICK, Auteur Article en page(s) : p.9 Langues : Anglais (eng) Mots-clés : Catatonia  Depression  Down syndrome  Intellectual disabilities  Psychosis Index. décimale : PER Périodiques Résumé : BACKGROUND: Relative to other aspects of Down syndrome, remarkably little is known about the psychiatric problems experienced by youth and young adults with this syndrome and if these problems differ from others with intellectual disabilities. Yet adolescence and young adulthood are particularly vulnerable time periods, as they involve multiple life transitions in educational, medical, and other service systems. METHODS: This study compared the psychiatric diagnoses of 49 adolescent and young adult patients with Down syndrome to 70 patients with other intellectual disabilities (IDs). The groups were similar in age, gender, and level of intellectual impairment. The 119 participants, aged 13 to 29 years (M = 21) were evaluated in one of two specialized psychiatric clinics. RESULTS: In contrast to previous literature, those with Down syndrome versus other IDs had significantly higher rates of psychosis NOS or depression with psychotic features (43% versus 13%). Unlike the ID group, psychosis was predominantly seen in females with Down syndrome. Marked motoric slowing in performing routine daily activities or in expressive language was manifested in 17% of patients with Down syndrome. No group differences were found in anxiety or depressive disorders, and the ID group had significantly higher rates of bipolar and impulse control disorders. CONCLUSIONS: These preliminary observations warrant further studies on genetic, neurological, and psychosocial factors that place some young people with Down syndrome or other IDs at high risk for severe psychiatric illness. En ligne : http://dx.doi.org/10.1186/s11689-015-9101-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347 [article] Psychiatric disorders in adolescents and young adults with Down syndrome and other intellectual disabilities [texte imprimé] / Elisabeth M. DYKENS, Auteur ; Bhavik SHAH, Auteur ; Bruce DAVIS, Auteur ; Cynthia BAKER, Auteur ; Taylor FIFE, Auteur ; Jeri FITZPATRICK, Auteur . - p.9. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.9 Mots-clés : Catatonia  Depression  Down syndrome  Intellectual disabilities  Psychosis Index. décimale : PER Périodiques Résumé : BACKGROUND: Relative to other aspects of Down syndrome, remarkably little is known about the psychiatric problems experienced by youth and young adults with this syndrome and if these problems differ from others with intellectual disabilities. Yet adolescence and young adulthood are particularly vulnerable time periods, as they involve multiple life transitions in educational, medical, and other service systems. METHODS: This study compared the psychiatric diagnoses of 49 adolescent and young adult patients with Down syndrome to 70 patients with other intellectual disabilities (IDs). The groups were similar in age, gender, and level of intellectual impairment. The 119 participants, aged 13 to 29 years (M = 21) were evaluated in one of two specialized psychiatric clinics. RESULTS: In contrast to previous literature, those with Down syndrome versus other IDs had significantly higher rates of psychosis NOS or depression with psychotic features (43% versus 13%). Unlike the ID group, psychosis was predominantly seen in females with Down syndrome. Marked motoric slowing in performing routine daily activities or in expressive language was manifested in 17% of patients with Down syndrome. No group differences were found in anxiety or depressive disorders, and the ID group had significantly higher rates of bipolar and impulse control disorders. CONCLUSIONS: These preliminary observations warrant further studies on genetic, neurological, and psychosocial factors that place some young people with Down syndrome or other IDs at high risk for severe psychiatric illness. En ligne : http://dx.doi.org/10.1186/s11689-015-9101-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347

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