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Auteur Daniel A. GELLER |
Documents disponibles écrits par cet auteur (2)
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Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis / Matti CERVIN in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)
[article]
Titre : Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.594-609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [?2.51, 4.21]; moderate), SRIs (MD: 3.07 [?0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: ?1.20 [?5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526
in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609[article] Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis [Texte imprimé et/ou numérique] / Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur . - p.594-609.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609
Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [?2.51, 4.21]; moderate), SRIs (MD: 3.07 [?0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: ?1.20 [?5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis / Amitai ABRAMOVITCH in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)
[article]
Titre : Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Amitai ABRAMOVITCH, Auteur ; Jonathan S. ABRAMOWITZ, Auteur ; Andrew MITTELMAN, Auteur ; Abigail STARK, Auteur ; Kesley RAMSEY, Auteur ; Daniel A. GELLER, Auteur Article en page(s) : p.837-847 Langues : Anglais (eng) Mots-clés : Obsessive–compulsive disorder pediatric neuropsychology meta-analysis executive function developmental cognitive functions Index. décimale : PER Périodiques Résumé : Background Research into the neuropsychology of pediatric obsessive–compulsive disorder (OCD) reveals inconsistent results, limiting the ability to draw conclusions about possible neurocognitive deficits in youth with OCD. The aim of this study was to conduct a meta-analysis of the available literature. Methods We identified 36 studies, of which 11 studies met inclusion criteria. Results were categorized into nine functional subdomains: planning, response inhibition/interference control, set shifting/cognitive flexibility, verbal memory, nonverbal memory, processing speed, working memory, visuospatial functions, and attention. For each domain, weighted pooled Hedges' g effect size was calculated using random model analyses. Results Small effect sizes were found across all subdomains, none of which were found to be statistically significant. Discussion Results indicate that youth with OCD do not exhibit noteworthy neuropsychological deficits. This is in line with recent suggestions that OCD may not be characterized by clinically meaningful neuropsychological impairments. However, the small number of available controlled studies highlights the urgent need for more neuropsychological research in this population, as well as for further exploration of the neurodevelopmental hypothesis in pediatric OCD. Finally, the relatively low persistence rates of OCD into adulthood should be taken under consideration, especially in the context of the putative neuropsychological performance differences between adult and pediatric OCD populations. En ligne : http://dx.doi.org/10.1111/jcpp.12414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263
in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.837-847[article] Research Review: Neuropsychological test performance in pediatric obsessive–compulsive disorder – a meta-analysis [Texte imprimé et/ou numérique] / Amitai ABRAMOVITCH, Auteur ; Jonathan S. ABRAMOWITZ, Auteur ; Andrew MITTELMAN, Auteur ; Abigail STARK, Auteur ; Kesley RAMSEY, Auteur ; Daniel A. GELLER, Auteur . - p.837-847.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-8 (August 2015) . - p.837-847
Mots-clés : Obsessive–compulsive disorder pediatric neuropsychology meta-analysis executive function developmental cognitive functions Index. décimale : PER Périodiques Résumé : Background Research into the neuropsychology of pediatric obsessive–compulsive disorder (OCD) reveals inconsistent results, limiting the ability to draw conclusions about possible neurocognitive deficits in youth with OCD. The aim of this study was to conduct a meta-analysis of the available literature. Methods We identified 36 studies, of which 11 studies met inclusion criteria. Results were categorized into nine functional subdomains: planning, response inhibition/interference control, set shifting/cognitive flexibility, verbal memory, nonverbal memory, processing speed, working memory, visuospatial functions, and attention. For each domain, weighted pooled Hedges' g effect size was calculated using random model analyses. Results Small effect sizes were found across all subdomains, none of which were found to be statistically significant. Discussion Results indicate that youth with OCD do not exhibit noteworthy neuropsychological deficits. This is in line with recent suggestions that OCD may not be characterized by clinically meaningful neuropsychological impairments. However, the small number of available controlled studies highlights the urgent need for more neuropsychological research in this population, as well as for further exploration of the neurodevelopmental hypothesis in pediatric OCD. Finally, the relatively low persistence rates of OCD into adulthood should be taken under consideration, especially in the context of the putative neuropsychological performance differences between adult and pediatric OCD populations. En ligne : http://dx.doi.org/10.1111/jcpp.12414 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263