Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale / Carly J. JOHNCO in Journal of Autism and Developmental Disorders, 45-10 (October 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3232-3242 Titre : Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale Type de document : Texte imprimé et/ou numérique Auteurs : Carly J. JOHNCO, Auteur ; Alessandro S. DE NADAI, Auteur ; Adam B. LEWIN, Auteur ; Jill EHRENREICH-MAY, Auteur ; Jeffrey J. WOOD, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.3232-3242 Langues : Anglais (eng) Mots-clés : Autism  Treatment  Pediatric Anxiety Rating Scale  Children  Measurement Index. décimale : PER Périodiques Résumé : This study examined optimal guidelines to assess treatment response and remission for anxiety in youth with autism spectrum disorders (ASD) using the Pediatric Anxiety Rating Scale (PARS). Data was collected for 108 children aged 7–16 years with comorbid anxiety and ASD before and after receiving cognitive behavior therapy. Optimal cut-offs on the PARS were assessed using signal detection analyses using receiver operating characteristic methods. Maximum agreement with response criteria was achieved at 15 % reduction in symptoms on the PARS. Maximum agreement with remission criteria was achieved at 40 % reduction in symptoms, or at a score of 10 or below at post-treatment. Results have implications for standardizing criteria used in research trials and clinical practice. En ligne : http://dx.doi.org/10.1007/s10803-015-2483-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 [article] Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale [Texte imprimé et/ou numérique] / Carly J. JOHNCO, Auteur ; Alessandro S. DE NADAI, Auteur ; Adam B. LEWIN, Auteur ; Jill EHRENREICH-MAY, Auteur ; Jeffrey J. WOOD, Auteur ; Eric A. STORCH, Auteur . - p.3232-3242. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3232-3242 Mots-clés : Autism  Treatment  Pediatric Anxiety Rating Scale  Children  Measurement Index. décimale : PER Périodiques Résumé : This study examined optimal guidelines to assess treatment response and remission for anxiety in youth with autism spectrum disorders (ASD) using the Pediatric Anxiety Rating Scale (PARS). Data was collected for 108 children aged 7–16 years with comorbid anxiety and ASD before and after receiving cognitive behavior therapy. Optimal cut-offs on the PARS were assessed using signal detection analyses using receiver operating characteristic methods. Maximum agreement with response criteria was achieved at 15 % reduction in symptoms on the PARS. Maximum agreement with remission criteria was achieved at 40 % reduction in symptoms, or at a score of 10 or below at post-treatment. Results have implications for standardizing criteria used in research trials and clinical practice. En ligne : http://dx.doi.org/10.1007/s10803-015-2483-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267

Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis / Matti CERVIN in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609 Titre : Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.594-609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [?2.51, 4.21]; moderate), SRIs (MD: 3.07 [?0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: ?1.20 [?5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis [Texte imprimé et/ou numérique] / Matti CERVIN, Auteur ; Joseph F. MCGUIRE, Auteur ; Johann M. D'SOUZA, Auteur ; Alessandro S. DE NADAI, Auteur ; Kristina ASPVALL, Auteur ; Wayne K. GOODMAN, Auteur ; Per ANDRÉN, Auteur ; Sophie C. SCHNEIDER, Auteur ; Daniel A. GELLER, Auteur ; David MATAIX-COLS, Auteur ; Eric A. STORCH, Auteur . - p.594-609. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.594-609 Index. décimale : PER Périodiques Résumé : Background Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT). Methods PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children's Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis). Results Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [?2.51, 4.21]; moderate), SRIs (MD: 3.07 [?0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: ?1.20 [?5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low. Conclusions In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed. En ligne : https://doi.org/10.1111/jcpp.13934 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

Erratum to: Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale / Carly J. JOHNCO in Journal of Autism and Developmental Disorders, 45-10 (October 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3243-3243 Titre : Erratum to: Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale Type de document : Texte imprimé et/ou numérique Auteurs : Carly J. JOHNCO, Auteur ; Alessandro S. DE NADAI, Auteur ; Adam B. LEWIN, Auteur ; Jill EHRENREICH-MAY, Auteur ; Jeffrey J. WOOD, Auteur ; Eric A. STORCH, Auteur Article en page(s) : p.3243-3243 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-015-2554-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267 [article] Erratum to: Defining Treatment Response and Symptom Remission for Anxiety Disorders in Pediatric Autism Spectrum Disorders Using the Pediatric Anxiety Rating Scale [Texte imprimé et/ou numérique] / Carly J. JOHNCO, Auteur ; Alessandro S. DE NADAI, Auteur ; Adam B. LEWIN, Auteur ; Jill EHRENREICH-MAY, Auteur ; Jeffrey J. WOOD, Auteur ; Eric A. STORCH, Auteur . - p.3243-3243. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3243-3243 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-015-2554-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=267

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