
- <Centre d'Information et de documentation du CRA Rhône-Alpes
- CRA
- Informations pratiques
-
Adresse
Centre d'information et de documentation
Horaires
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexLundi au Vendredi
Contact
9h00-12h00 13h30-16h00Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Adresse
Détail de l'auteur
Auteur C. RATTAZ |
Documents disponibles écrits par cet auteur (3)



Adaptive trajectories and early risk factors in the autism spectrum: A 15-year prospective study / Amaria BAGHDADLI in Autism Research, 11-11 (November 2018)
![]()
[article]
Titre : Adaptive trajectories and early risk factors in the autism spectrum: A 15-year prospective study Type de document : Texte imprimé et/ou numérique Auteurs : Amaria BAGHDADLI, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; M. C. PICOT, Auteur ; S. MIOT, Auteur ; Sandrine SONIE, Auteur ; C. RATTAZ, Auteur ; Laurent MOTTRON, Auteur Article en page(s) : p.1455-1467 Langues : Anglais (eng) Mots-clés : adaptative level autism spectrum developmental trajectories early adulthood Index. décimale : PER Périodiques Résumé : Little is known about long-term outcomes. We investigate the adaptive trajectories and their risk factors in ASD. Data were obtained from 281 children prospectively followed untill adulthood. The final sample consisted of 106 individuals. Vineland scores were collected at baseline (T1), 3 (T2), 10 (T3), and 15 (T4) years later. A group-based method was used to identify homogeneous patterns of adaptive skills trajectories. Results show that among the children initially categorized as autistic, 82.6% remained over the ADOS diagnostic threshold, 11.9% converted to atypical autism, and 5.4% fell under the ADOS threshold. Most atypical autism diagnoses were unstable. Most (81.7%) autistic participants had an ID at inclusion. At T1, 59.3% were nonverbal, but only 39% at T4. Most changes occurred between 4 and 8 years of age. Approximately 25% of participants exhibited a "high" growth trajectory, in which progress continues throughout adolescence, and 75% a "low" growth trajectory, characterized by greater autistic symptoms, intellectual disability, and lower language abilities reflected by high CARS scores, low apparent DQ, and speech difficulties, which mostly, but not always, predicted low trajectories. Our findings suggest that the adaptive prognosis of autism is mostly poor in this cohort, biased toward intellectual disability. However, changes in diagnostic, speech, and adaptive status are not uncommon, even for indivduals with low measured intelligence or apparent intellectual disability, and are sometimes difficult to predict. Autism Research 2018, 11: 1455-1467. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Most autism diagnoses given before 5 years of age are stable to adulthood, but one-fifth of individuals are no longer considered to be autistic, even in a cohort biased toward apparent intellectual disability. Conversely, atypical autism diagnoses are mostly unstable. One-third of children who are nonverbal at 5 years are verbal within 15 years, mostly before 8 years of age. Concerning adaptive behavior outcomes, only one-fourth of children exhibit a high-growth trajectory through at least 15 years. En ligne : http://dx.doi.org/10.1002/aur.2022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370
in Autism Research > 11-11 (November 2018) . - p.1455-1467[article] Adaptive trajectories and early risk factors in the autism spectrum: A 15-year prospective study [Texte imprimé et/ou numérique] / Amaria BAGHDADLI, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; M. C. PICOT, Auteur ; S. MIOT, Auteur ; Sandrine SONIE, Auteur ; C. RATTAZ, Auteur ; Laurent MOTTRON, Auteur . - p.1455-1467.
Langues : Anglais (eng)
in Autism Research > 11-11 (November 2018) . - p.1455-1467
Mots-clés : adaptative level autism spectrum developmental trajectories early adulthood Index. décimale : PER Périodiques Résumé : Little is known about long-term outcomes. We investigate the adaptive trajectories and their risk factors in ASD. Data were obtained from 281 children prospectively followed untill adulthood. The final sample consisted of 106 individuals. Vineland scores were collected at baseline (T1), 3 (T2), 10 (T3), and 15 (T4) years later. A group-based method was used to identify homogeneous patterns of adaptive skills trajectories. Results show that among the children initially categorized as autistic, 82.6% remained over the ADOS diagnostic threshold, 11.9% converted to atypical autism, and 5.4% fell under the ADOS threshold. Most atypical autism diagnoses were unstable. Most (81.7%) autistic participants had an ID at inclusion. At T1, 59.3% were nonverbal, but only 39% at T4. Most changes occurred between 4 and 8 years of age. Approximately 25% of participants exhibited a "high" growth trajectory, in which progress continues throughout adolescence, and 75% a "low" growth trajectory, characterized by greater autistic symptoms, intellectual disability, and lower language abilities reflected by high CARS scores, low apparent DQ, and speech difficulties, which mostly, but not always, predicted low trajectories. Our findings suggest that the adaptive prognosis of autism is mostly poor in this cohort, biased toward intellectual disability. However, changes in diagnostic, speech, and adaptive status are not uncommon, even for indivduals with low measured intelligence or apparent intellectual disability, and are sometimes difficult to predict. Autism Research 2018, 11: 1455-1467. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Most autism diagnoses given before 5 years of age are stable to adulthood, but one-fifth of individuals are no longer considered to be autistic, even in a cohort biased toward apparent intellectual disability. Conversely, atypical autism diagnoses are mostly unstable. One-third of children who are nonverbal at 5 years are verbal within 15 years, mostly before 8 years of age. Concerning adaptive behavior outcomes, only one-fourth of children exhibit a high-growth trajectory through at least 15 years. En ligne : http://dx.doi.org/10.1002/aur.2022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 Correction to: Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
![]()
[article]
Titre : Correction to: Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur Article en page(s) : p.2257 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained the following omissions. En ligne : https://dx.doi.org/10.1007/s10803-019-03950-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2257[article] Correction to: Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort [Texte imprimé et/ou numérique] / Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur . - p.2257.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2257
Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained the following omissions. En ligne : https://dx.doi.org/10.1007/s10803-019-03950-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
![]()
[article]
Titre : Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur Article en page(s) : p.2243-2256 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Cohort France Long-term follow-up Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256[article] Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort [Texte imprimé et/ou numérique] / Amaria BAGHDADLI, Auteur ; C. RATTAZ, Auteur ; C. MICHELON, Auteur ; E. PERNON, Auteur ; Kerim M. MUNIR, Auteur . - p.2243-2256.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256
Mots-clés : Autism spectrum disorders Cohort France Long-term follow-up Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400