Genetic underpinnings of callous-unemotional traits and emotion recognition in children, adolescents, and emerging adults / A. A. MOORE in Journal of Child Psychology and Psychiatry, 60-6 (June 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-6 (June 2019) . - p.638-645 Titre : Genetic underpinnings of callous-unemotional traits and emotion recognition in children, adolescents, and emerging adults Type de document : Texte imprimé et/ou numérique Auteurs : A. A. MOORE, Auteur ; L. M. RAPPAPORT, Auteur ; James R. BLAIR, Auteur ; D. S. PINE, Auteur ; E. LEIBENLUFT, Auteur ; Melissa A. BROTMAN, Auteur ; J. M. HETTEMA, Auteur ; R. ROBERSON-NAY, Auteur Article en page(s) : p.638-645 Langues : Anglais (eng) Mots-clés : Callous-unemotional traits  emotion recognition  genetics  psychopathy  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-Unemotional (CU) and psychopathic traits are consistently associated with impaired recognition of others' emotions, specifically fear and sadness. However, no studies have examined whether the association between CU traits and emotion recognition deficits is due primarily to genetic or environmental factors. METHODS: The current study used data from 607 Caucasian twin pairs (N = 1,214 twins) to examine the phenotypic and genetic relationship between the Inventory of Callous-Unemotional Traits (ICU) and facial emotion recognition assessed via the laboratory-based Facial Expression Labeling Task (FELT). RESULTS: The uncaring/callous dimension of the ICU was significantly associated with impaired recognition of happiness, sadness, fear, surprise, and disgust. The unemotional ICU dimension was significantly associated with improved recognition of surprise and disgust. Total ICU score was significantly associated with impaired recognition of sadness. Significant genetic correlations were found for uncaring/callous traits and distress cue recognition (i.e. fear and sadness). The observed relationship between uncaring/callous traits and deficits in distress cue recognition was accounted for entirely by shared genetic influences. CONCLUSIONS: The results of the current study replicate previous findings demonstrating impaired emotion recognition among youth with elevated CU traits. We extend these findings by replicating them in an epidemiological sample not selected or enriched for pathological levels of CU traits. Furthermore, the current study is the first to investigate the genetic and environmental etiology of CU traits and emotion recognition, and results suggest genetic influences underlie the specific relationship between uncaring/callous traits and distress cue (fear/sadness) recognition in others. En ligne : http://dx.doi.org/10.1111/jcpp.13018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397 [article] Genetic underpinnings of callous-unemotional traits and emotion recognition in children, adolescents, and emerging adults [Texte imprimé et/ou numérique] / A. A. MOORE, Auteur ; L. M. RAPPAPORT, Auteur ; James R. BLAIR, Auteur ; D. S. PINE, Auteur ; E. LEIBENLUFT, Auteur ; Melissa A. BROTMAN, Auteur ; J. M. HETTEMA, Auteur ; R. ROBERSON-NAY, Auteur . - p.638-645. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-6 (June 2019) . - p.638-645 Mots-clés : Callous-unemotional traits  emotion recognition  genetics  psychopathy  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-Unemotional (CU) and psychopathic traits are consistently associated with impaired recognition of others' emotions, specifically fear and sadness. However, no studies have examined whether the association between CU traits and emotion recognition deficits is due primarily to genetic or environmental factors. METHODS: The current study used data from 607 Caucasian twin pairs (N = 1,214 twins) to examine the phenotypic and genetic relationship between the Inventory of Callous-Unemotional Traits (ICU) and facial emotion recognition assessed via the laboratory-based Facial Expression Labeling Task (FELT). RESULTS: The uncaring/callous dimension of the ICU was significantly associated with impaired recognition of happiness, sadness, fear, surprise, and disgust. The unemotional ICU dimension was significantly associated with improved recognition of surprise and disgust. Total ICU score was significantly associated with impaired recognition of sadness. Significant genetic correlations were found for uncaring/callous traits and distress cue recognition (i.e. fear and sadness). The observed relationship between uncaring/callous traits and deficits in distress cue recognition was accounted for entirely by shared genetic influences. CONCLUSIONS: The results of the current study replicate previous findings demonstrating impaired emotion recognition among youth with elevated CU traits. We extend these findings by replicating them in an epidemiological sample not selected or enriched for pathological levels of CU traits. Furthermore, the current study is the first to investigate the genetic and environmental etiology of CU traits and emotion recognition, and results suggest genetic influences underlie the specific relationship between uncaring/callous traits and distress cue (fear/sadness) recognition in others. En ligne : http://dx.doi.org/10.1111/jcpp.13018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397

Heritability, stability, and prevalence of tonic and phasic irritability as indicators of disruptive mood dysregulation disorder / A. A. MOORE in Journal of Child Psychology and Psychiatry, 60-9 (September 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-9 (September 2019) . - p.1032-1041 Titre : Heritability, stability, and prevalence of tonic and phasic irritability as indicators of disruptive mood dysregulation disorder Type de document : Texte imprimé et/ou numérique Auteurs : A. A. MOORE, Auteur ; D. M. LAPATO, Auteur ; Melissa A. BROTMAN, Auteur ; E. LEIBENLUFT, Auteur ; S. H. AGGEN, Auteur ; J. M. HETTEMA, Auteur ; T. P. YORK, Auteur ; J. L. SILBERG, Auteur ; R. ROBERSON-NAY, Auteur Article en page(s) : p.1032-1041 Langues : Anglais (eng) Mots-clés : Disruptive behavior  emotional dysregulation  heritability  mood disorder  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Little is known about genetic and environmental influences on the components of disruptive mood dysregulation disorder (DMDD), tonic irritability (i.e., irritable mood) and phasic irritability (i.e., temper outbursts). This study examined prevalence, stability, and heritability of tonic irritability, phasic irritability, and a DMDD proxy (pDMDD) based on DSM-5 criteria. METHODS: pDMDD was derived using data from clinical interviews of parents and their twins (N = 1,431 twin pairs), ages 8-17, participating in Waves 1 and 2 of the Virginia Twin Study of Adolescent Behavioral Development. Biometrical modeling was used to compare a common pathway model (CPM) and an independent pathway model (IPM), and heritability estimates were obtained for pDMDD using the symptoms of irritable mood (tonic irritability; DMDD Criterion D), intense temper outbursts (phasic irritability; DMDD Criterion A), and frequent temper outbursts (phasic irritability; DMDD Criterion C). RESULTS: Lifetime prevalence of pDMDD was 7.46%. The stability of DMDD symptoms and the pDMDD phenotype across approximately one year were moderate (.30-.69). A CPM was a better fit to the data than an IPM. Phasic irritability loaded strongly onto the pDMDD latent factor (.89-.96) whereas tonic irritability did not (.28). Genetic influences accounted for approximately 59% of the variance in the latent pDMDD phenotype, with the remaining 41% of the variance due to unique environmental effects. The heritability of tonic irritability (54%) was slightly lower than that of frequent and intense temper (components of phasic irritability; 61% and 63%, respectively). CONCLUSIONS: Compared to tonic irritability, phasic irritability appears to be slightly more stable and heritable, as well as a stronger indicator of the latent factor. Furthermore, environmental experiences appear to play a substantial role in the development of irritability and DMDD, and researchers should seek to elucidate these mechanisms in future work. En ligne : http://dx.doi.org/10.1111/jcpp.13062 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 [article] Heritability, stability, and prevalence of tonic and phasic irritability as indicators of disruptive mood dysregulation disorder [Texte imprimé et/ou numérique] / A. A. MOORE, Auteur ; D. M. LAPATO, Auteur ; Melissa A. BROTMAN, Auteur ; E. LEIBENLUFT, Auteur ; S. H. AGGEN, Auteur ; J. M. HETTEMA, Auteur ; T. P. YORK, Auteur ; J. L. SILBERG, Auteur ; R. ROBERSON-NAY, Auteur . - p.1032-1041. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-9 (September 2019) . - p.1032-1041 Mots-clés : Disruptive behavior  emotional dysregulation  heritability  mood disorder  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Little is known about genetic and environmental influences on the components of disruptive mood dysregulation disorder (DMDD), tonic irritability (i.e., irritable mood) and phasic irritability (i.e., temper outbursts). This study examined prevalence, stability, and heritability of tonic irritability, phasic irritability, and a DMDD proxy (pDMDD) based on DSM-5 criteria. METHODS: pDMDD was derived using data from clinical interviews of parents and their twins (N = 1,431 twin pairs), ages 8-17, participating in Waves 1 and 2 of the Virginia Twin Study of Adolescent Behavioral Development. Biometrical modeling was used to compare a common pathway model (CPM) and an independent pathway model (IPM), and heritability estimates were obtained for pDMDD using the symptoms of irritable mood (tonic irritability; DMDD Criterion D), intense temper outbursts (phasic irritability; DMDD Criterion A), and frequent temper outbursts (phasic irritability; DMDD Criterion C). RESULTS: Lifetime prevalence of pDMDD was 7.46%. The stability of DMDD symptoms and the pDMDD phenotype across approximately one year were moderate (.30-.69). A CPM was a better fit to the data than an IPM. Phasic irritability loaded strongly onto the pDMDD latent factor (.89-.96) whereas tonic irritability did not (.28). Genetic influences accounted for approximately 59% of the variance in the latent pDMDD phenotype, with the remaining 41% of the variance due to unique environmental effects. The heritability of tonic irritability (54%) was slightly lower than that of frequent and intense temper (components of phasic irritability; 61% and 63%, respectively). CONCLUSIONS: Compared to tonic irritability, phasic irritability appears to be slightly more stable and heritable, as well as a stronger indicator of the latent factor. Furthermore, environmental experiences appear to play a substantial role in the development of irritability and DMDD, and researchers should seek to elucidate these mechanisms in future work. En ligne : http://dx.doi.org/10.1111/jcpp.13062 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405

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