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The urinary 1H-NMR metabolomics profile of an italian autistic children population and their unaffected siblings / Milena LUSSU in Autism Research, 10-6 (June 2017)
[article]
Titre : The urinary 1H-NMR metabolomics profile of an italian autistic children population and their unaffected siblings Type de document : Texte imprimé et/ou numérique Auteurs : Milena LUSSU, Auteur ; Antonio NOTO, Auteur ; Alice MASILI, Auteur ; Andrea C. RINALDI, Auteur ; Angelica DESSÌ, Auteur ; Maria DE ANGELIS, Auteur ; Andrea DE GIACOMO, Auteur ; Vassilios FANOS, Auteur ; Luigi ATZORI, Auteur ; Ruggiero FRANCAVILLA, Auteur Article en page(s) : p.1058-1066 Langues : Anglais (eng) Mots-clés : metabolomics autistic children siblings biomarkers Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) make a dishomogeneous group of psychiatric diseases having either genetic and environmental components, including changes of the microbiota. The rate of diagnosis, based on a series of psychological tests and observed behavior, dramatically increased in the past few decades. Currently, no biological markers are available and the pathogenesis is not defined. The purpose of this study was to evaluate the potential use of 1H-NMR metabolomics to analyze the global biochemical signature of ASD patients (n?=?21) and controls (n?=?21), these being siblings of autistic patients. A multivariate model has been used to extrapolate the variables of importance. The discriminating urinary metabolites were identified; in particular, significantly increased levels of hippurate, glycine, creatine, tryptophan, and d-threitol and decreased concentrations of glutamate, creatinine, lactate, valine, betaine, and taurine were observed in ASD patients. Based on the identified discriminant metabolites, the attention was focused on two possible mechanisms that could be involved in ASD: oxidative stress conditions and gut microflora modifications. In conclusion, nuclear magnetic resonance-based metabolomics analysis of the urine seems to have the potential for the identification of a metabolic fingerprint of ASD phenotypes and appears to be suitable for further investigation of the disease mechanisms. En ligne : http://dx.doi.org/10.1002/aur.1748 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309
in Autism Research > 10-6 (June 2017) . - p.1058-1066[article] The urinary 1H-NMR metabolomics profile of an italian autistic children population and their unaffected siblings [Texte imprimé et/ou numérique] / Milena LUSSU, Auteur ; Antonio NOTO, Auteur ; Alice MASILI, Auteur ; Andrea C. RINALDI, Auteur ; Angelica DESSÌ, Auteur ; Maria DE ANGELIS, Auteur ; Andrea DE GIACOMO, Auteur ; Vassilios FANOS, Auteur ; Luigi ATZORI, Auteur ; Ruggiero FRANCAVILLA, Auteur . - p.1058-1066.
Langues : Anglais (eng)
in Autism Research > 10-6 (June 2017) . - p.1058-1066
Mots-clés : metabolomics autistic children siblings biomarkers Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) make a dishomogeneous group of psychiatric diseases having either genetic and environmental components, including changes of the microbiota. The rate of diagnosis, based on a series of psychological tests and observed behavior, dramatically increased in the past few decades. Currently, no biological markers are available and the pathogenesis is not defined. The purpose of this study was to evaluate the potential use of 1H-NMR metabolomics to analyze the global biochemical signature of ASD patients (n?=?21) and controls (n?=?21), these being siblings of autistic patients. A multivariate model has been used to extrapolate the variables of importance. The discriminating urinary metabolites were identified; in particular, significantly increased levels of hippurate, glycine, creatine, tryptophan, and d-threitol and decreased concentrations of glutamate, creatinine, lactate, valine, betaine, and taurine were observed in ASD patients. Based on the identified discriminant metabolites, the attention was focused on two possible mechanisms that could be involved in ASD: oxidative stress conditions and gut microflora modifications. In conclusion, nuclear magnetic resonance-based metabolomics analysis of the urine seems to have the potential for the identification of a metabolic fingerprint of ASD phenotypes and appears to be suitable for further investigation of the disease mechanisms. En ligne : http://dx.doi.org/10.1002/aur.1748 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309 The use of amphetamines in hyperactivity / Leon Jr OETTINGER in Developmental Medicine & Child Neurology, 17-1 (February 1975)
[article]
Titre : The use of amphetamines in hyperactivity Type de document : Texte imprimé et/ou numérique Auteurs : Leon Jr OETTINGER, Auteur Année de publication : 1975 Article en page(s) : p.117 Langues : Anglais (eng) Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435
in Developmental Medicine & Child Neurology > 17-1 (February 1975) . - p.117[article] The use of amphetamines in hyperactivity [Texte imprimé et/ou numérique] / Leon Jr OETTINGER, Auteur . - 1975 . - p.117.
Langues : Anglais (eng)
in Developmental Medicine & Child Neurology > 17-1 (February 1975) . - p.117
Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 The use of behavior modeling training in a mobile app parent training program to improve functional communication of young children with autism spectrum disorder / G. C. LAW in Autism, 22-4 (May 2018)
[article]
Titre : The use of behavior modeling training in a mobile app parent training program to improve functional communication of young children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : G. C. LAW, Auteur ; M. NEIHART, Auteur ; A. DUTT, Auteur Article en page(s) : p.424-439 Langues : Anglais (eng) Mots-clés : autism intervention behavior modeling training mobile technology naturalistic developmental and behavioral intervention parent training Index. décimale : PER Périodiques Résumé : Communication intervention in early life can significantly impact long-term outcomes for young children with autism. Parents can be vital resources in the midst of the current manpower shortage. Map4speech is a new mobile application developed for parents of children with autism spectrum disorder. It is specially designed to provide high-quality, interactive learning, coupled with frequent feedback and live coaching to train parents in a naturalistic language intervention. A multiple-baseline single-case experimental design was conducted across three parent-child dyads. Results indicate that procedural integrity of parents' intervention techniques was above 85% during post-training intervention, and their respective children showed increases in spontaneous word/gesture use. The results show that mobile applications with feedback can be a promising means for improving efficiency and effectiveness in disseminating evidence-based practices for autism intervention. En ligne : http://dx.doi.org/10.1177/1362361316683887 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=361
in Autism > 22-4 (May 2018) . - p.424-439[article] The use of behavior modeling training in a mobile app parent training program to improve functional communication of young children with autism spectrum disorder [Texte imprimé et/ou numérique] / G. C. LAW, Auteur ; M. NEIHART, Auteur ; A. DUTT, Auteur . - p.424-439.
Langues : Anglais (eng)
in Autism > 22-4 (May 2018) . - p.424-439
Mots-clés : autism intervention behavior modeling training mobile technology naturalistic developmental and behavioral intervention parent training Index. décimale : PER Périodiques Résumé : Communication intervention in early life can significantly impact long-term outcomes for young children with autism. Parents can be vital resources in the midst of the current manpower shortage. Map4speech is a new mobile application developed for parents of children with autism spectrum disorder. It is specially designed to provide high-quality, interactive learning, coupled with frequent feedback and live coaching to train parents in a naturalistic language intervention. A multiple-baseline single-case experimental design was conducted across three parent-child dyads. Results indicate that procedural integrity of parents' intervention techniques was above 85% during post-training intervention, and their respective children showed increases in spontaneous word/gesture use. The results show that mobile applications with feedback can be a promising means for improving efficiency and effectiveness in disseminating evidence-based practices for autism intervention. En ligne : http://dx.doi.org/10.1177/1362361316683887 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=361 The Use Of A Calcium-Channel Blocker, Nicardipine, For Severely Asphyxiated Newborn Infants / Malcolm I. LEVENE in Developmental Medicine & Child Neurology, 32-7 (July 1990)
[article]
Titre : The Use Of A Calcium-Channel Blocker, Nicardipine, For Severely Asphyxiated Newborn Infants Type de document : Texte imprimé et/ou numérique Auteurs : Malcolm I. LEVENE, Auteur ; Neil A. GIBSON, Auteur ; Alan C. FENTON, Auteur ; Eugenia PAPATHOMA, Auteur ; David BARNETT, Auteur Année de publication : 1990 Article en page(s) : p.567-574 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : La nicardipine chez les nouveaux-nés présentant une asphyxie sévère
Une perfusion continue de nicardipine a été administrée chez quatre nouveaux-nés a terme avec asphyxie sévére qui présentaient un risque élevé de devenir pathologique et avaient présenté des résultats anormaux aux études hémodynamiques cérébrales avec doppler. Le rythme cardiaque s'accrût chez les quatres nouveaux-nés et la pression artérielle moyenne (MAP) diminua dans trois cas. Deux nourrissons avaient présenté une chute soudaine et marquée de la MAP, ainsi qu'une altération grave de la circulation sanguine cutanée et une chute simultanée de la vitesse de circulation sanguine cérébrale. Le taux sérique de nicardipine était <40ng/mL dans tous les cas. L'utilisation de nicardipine et éventuellement d'autres bloqueurs des canaux calciques peut étre associée avec une hypotension marquée et s'il n'y a pas d'auto-régulation cérébrale, cela peut créer une hypo-perfusion ultérieure; aussi l'utilisation de ces médications ne doit être tentée que si la pression sanguine est soigneusement contrôlée.Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=134
in Developmental Medicine & Child Neurology > 32-7 (July 1990) . - p.567-574[article] The Use Of A Calcium-Channel Blocker, Nicardipine, For Severely Asphyxiated Newborn Infants [Texte imprimé et/ou numérique] / Malcolm I. LEVENE, Auteur ; Neil A. GIBSON, Auteur ; Alan C. FENTON, Auteur ; Eugenia PAPATHOMA, Auteur ; David BARNETT, Auteur . - 1990 . - p.567-574.
Langues : Anglais (eng)
in Developmental Medicine & Child Neurology > 32-7 (July 1990) . - p.567-574
Index. décimale : PER Périodiques Résumé : La nicardipine chez les nouveaux-nés présentant une asphyxie sévère
Une perfusion continue de nicardipine a été administrée chez quatre nouveaux-nés a terme avec asphyxie sévére qui présentaient un risque élevé de devenir pathologique et avaient présenté des résultats anormaux aux études hémodynamiques cérébrales avec doppler. Le rythme cardiaque s'accrût chez les quatres nouveaux-nés et la pression artérielle moyenne (MAP) diminua dans trois cas. Deux nourrissons avaient présenté une chute soudaine et marquée de la MAP, ainsi qu'une altération grave de la circulation sanguine cutanée et une chute simultanée de la vitesse de circulation sanguine cérébrale. Le taux sérique de nicardipine était <40ng/mL dans tous les cas. L'utilisation de nicardipine et éventuellement d'autres bloqueurs des canaux calciques peut étre associée avec une hypotension marquée et s'il n'y a pas d'auto-régulation cérébrale, cela peut créer une hypo-perfusion ultérieure; aussi l'utilisation de ces médications ne doit être tentée que si la pression sanguine est soigneusement contrôlée.Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=134 The Use of Cell Phones to Address Safety Skills for Students With a Moderate ID in Community-Based Settings / Laura A. BASSETTE in Focus on Autism and Other Developmental Disabilities, 33-2 (June 2018)
[article]
Titre : The Use of Cell Phones to Address Safety Skills for Students With a Moderate ID in Community-Based Settings Type de document : Texte imprimé et/ou numérique Auteurs : Laura A. BASSETTE, Auteur ; Teresa TABER-DOUGHTY, Auteur ; Roberto I. GAMA, Auteur ; Paul A. ALBERTO, Auteur ; Gulnoza YAKUBOVA, Auteur ; David CIHAK, Auteur Article en page(s) : p.100-110 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The purpose of this study was to examine the impact of a video modeling (VM) intervention in conjunction with a system of least prompts (SLP) to teach safety skills using cell phones to students with a moderate intellectual disability. A multiple-probe design across three participants was used to assess student acquisition in taking and sending a picture of a key identifier (i.e., a sign) during a role-play scenario in which students pretended to be lost in the community. Intervention sessions were conducted at the students? middle school, at their community-based instruction site, and at an unfamiliar community location. All students successfully learned to take and send the picture in the community locations at the mastery criterion and generalized the skills at an unfamiliar community site. Implications of the use of VM to address the integration of technology with safety skill instruction and other areas of future research are discussed. En ligne : https://doi.org/10.1177/1088357616667590 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363
in Focus on Autism and Other Developmental Disabilities > 33-2 (June 2018) . - p.100-110[article] The Use of Cell Phones to Address Safety Skills for Students With a Moderate ID in Community-Based Settings [Texte imprimé et/ou numérique] / Laura A. BASSETTE, Auteur ; Teresa TABER-DOUGHTY, Auteur ; Roberto I. GAMA, Auteur ; Paul A. ALBERTO, Auteur ; Gulnoza YAKUBOVA, Auteur ; David CIHAK, Auteur . - p.100-110.
Langues : Anglais (eng)
in Focus on Autism and Other Developmental Disabilities > 33-2 (June 2018) . - p.100-110
Index. décimale : PER Périodiques Résumé : The purpose of this study was to examine the impact of a video modeling (VM) intervention in conjunction with a system of least prompts (SLP) to teach safety skills using cell phones to students with a moderate intellectual disability. A multiple-probe design across three participants was used to assess student acquisition in taking and sending a picture of a key identifier (i.e., a sign) during a role-play scenario in which students pretended to be lost in the community. Intervention sessions were conducted at the students? middle school, at their community-based instruction site, and at an unfamiliar community location. All students successfully learned to take and send the picture in the community locations at the mastery criterion and generalized the skills at an unfamiliar community site. Implications of the use of VM to address the integration of technology with safety skill instruction and other areas of future research are discussed. En ligne : https://doi.org/10.1177/1088357616667590 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363 The use of chloral hydrate for refractory childhood epilepsy / Teyrnon G POWELL in Developmental Medicine & Child Neurology, 25-4 (August 1983)
PermalinkThe Use of Cognitive-Behavioural Therapy with People with Asperger Syndrome: A Case Study / Dougal Julian HARE in Autism, 1-2 (November 1997)
PermalinkThe Use of Control Systems Analysis in the Neurophysiology of Eye Movements / D. A. ROBINSON in Annual Review of Neuroscience, 4 (1981)
PermalinkThe Use of Eye Tracking as a Biomarker of Treatment Outcome in a Pilot Randomized Clinical Trial for Young Children with Autism / Jessica BRADSHAW in Autism Research, 12-5 (May 2019)
PermalinkThe use of eye-tracking to explore social difficulties in cognitively able students with autism spectrum disorder: A pilot investigation / Mary HANLEY in Autism, 19-7 (October 2015)
PermalinkThe Use of Grammatical Morphemes by Mandarin-Speaking Children with High Functioning Autism / Peng ZHOU in Journal of Autism and Developmental Disorders, 45-5 (May 2015)
PermalinkThe Use of in Vitro Brain Slices for Multidisciplinary Studies of Synaptic Function / Gary LYNCH in Annual Review of Neuroscience, 3 (1980)
PermalinkThe use of innovative computer technology for teaching social communication to individuals with autism spectrum disorders / Allison L. WAINER in Research in Autism Spectrum Disorders, 5-1 (January-March 2011)
PermalinkThe use of instructive feedback for teaching language skills to children with autism / Lara DELMOLINO in Research in Autism Spectrum Disorders, 7-6 (June 2013)
PermalinkThe Use of Linguistic Cues in Sentence Comprehension by Mandarin-Speaking Children with High-Functioning Autism / Peng ZHOU in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
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