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Psychosocial Adversities Underestimated in Hyperkinetic Children / S. OVERMEYER in Journal of Child Psychology and Psychiatry, 40-2 (February 1999)
[article]
Titre : Psychosocial Adversities Underestimated in Hyperkinetic Children Type de document : Texte imprimé et/ou numérique Auteurs : S. OVERMEYER, Auteur ; E. TAYLOR, Auteur ; B. BLANZ, Auteur ; Martin H. SCHMIDT, Auteur Année de publication : 1999 Article en page(s) : p.259-263 Langues : Anglais (eng) Mots-clés : Hyperkinetic disorder conduct disorder attention deficit hyperactivity disorder family factors assessment Index. décimale : PER Périodiques Résumé : Abnormal psychosocial factors, assessed both clinically and by raters blind to clinical presentation, were examined in 21 hyperkinetic and 26 conduct disordered children. Blind raters found the frequency of psychosocial adversities to be similar in the two disorders. By contrast the clinical rater, who did know the diagnosis of patients, rated adverse psychosocial situations as much lower in hyperkinetic children than in children with conduct disorder. Logistic regression showed, particularly in the category of abnormal intrafamilial relationships (Lack of warmth in parent child relationship, Hostility or scapegoating of the child, Intrafamilial discord among adults), effects of the interaction between rater and knowledge of diagnosis. Clinical raters should be aware of abnormal psychosocial situations in hyperkinetic children and assess possible adverse effects on parents and children. Researchers should be aware of a possible bias in research interviews. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124
in Journal of Child Psychology and Psychiatry > 40-2 (February 1999) . - p.259-263[article] Psychosocial Adversities Underestimated in Hyperkinetic Children [Texte imprimé et/ou numérique] / S. OVERMEYER, Auteur ; E. TAYLOR, Auteur ; B. BLANZ, Auteur ; Martin H. SCHMIDT, Auteur . - 1999 . - p.259-263.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 40-2 (February 1999) . - p.259-263
Mots-clés : Hyperkinetic disorder conduct disorder attention deficit hyperactivity disorder family factors assessment Index. décimale : PER Périodiques Résumé : Abnormal psychosocial factors, assessed both clinically and by raters blind to clinical presentation, were examined in 21 hyperkinetic and 26 conduct disordered children. Blind raters found the frequency of psychosocial adversities to be similar in the two disorders. By contrast the clinical rater, who did know the diagnosis of patients, rated adverse psychosocial situations as much lower in hyperkinetic children than in children with conduct disorder. Logistic regression showed, particularly in the category of abnormal intrafamilial relationships (Lack of warmth in parent child relationship, Hostility or scapegoating of the child, Intrafamilial discord among adults), effects of the interaction between rater and knowledge of diagnosis. Clinical raters should be aware of abnormal psychosocial situations in hyperkinetic children and assess possible adverse effects on parents and children. Researchers should be aware of a possible bias in research interviews. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 The risk of attention deficit hyperactivity disorder in children exposed to maternal smoking during pregnancy – a re-examination using a sibling design / Carsten OBEL in Journal of Child Psychology and Psychiatry, 57-4 (April 2016)
[article]
Titre : The risk of attention deficit hyperactivity disorder in children exposed to maternal smoking during pregnancy – a re-examination using a sibling design Type de document : Texte imprimé et/ou numérique Auteurs : Carsten OBEL, Auteur ; Jin Liang ZHU, Auteur ; Jørn OLSEN, Auteur ; Sanni BREINING, Auteur ; Jiong LI, Auteur ; Therese K. GRØNBORG, Auteur ; Mika GISSLER, Auteur ; Michael RUTTER, Auteur Article en page(s) : p.532-537 Langues : Anglais (eng) Mots-clés : Smoking pregnancy attention deficit hyperactivity disorder hyperkinetic disorder sibling design Index. décimale : PER Périodiques Résumé : Background Conventional cohort studies have consistently shown that exposure to maternal smoking in pregnancy is associated with about twice the risk of attention deficit hyperactivity disorder (ADHD) in the offspring. However, recent studies using alternative designs to disentangle the effect of social and genetic confounders have suggested that confounding may account for the association. In this study we aimed to estimate the association by a sibling design. Methods We used a design with half and full siblings in a Danish national register-based cohort on all singletons born between January 1991 and December 2006 and followed until January 2011. Data were available for 90% (N = 968,665) of the singleton live births in the period. We used the combination of the International Classification of Diseases (10th version) diagnosis of hyperkinetic disorder (HKD) and ADHD medication to identify children. We used sibling-matched (conditional) Cox regression to control social and genetic confounding. Results Using conventional cohort analyses, we found the expected association between pregnancy smoking and offspring ADHD (adjusted HR 2.01, 95% CI 1.94–2.07). In the sibling analysis, however, we did not detect such a strong association (adjusted HR 1.07, 95% CI 0.94–1.22). There was no difference between results for half- and full sibling analyses. The link between pregnancy smoking and low birth weight remained robust in the sibling design (adjusted OR 1.68, 95% CI 1.33–2.12). Conclusions We found no support for prenatal smoking as a strong causal factor in ADHD. Our findings suggest that the strong association found in most previous epidemiological studies is likely to be due to a strong link between maternal smoking and maternal ADHD genetics or shared family environment. Pregnant women should still be encouraged to stop smoking because of other risks, but we have no reason to believe that this would reduce the risk of ADHD in the offspring. En ligne : http://dx.doi.org/10.1111/jcpp.12478 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285
in Journal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.532-537[article] The risk of attention deficit hyperactivity disorder in children exposed to maternal smoking during pregnancy – a re-examination using a sibling design [Texte imprimé et/ou numérique] / Carsten OBEL, Auteur ; Jin Liang ZHU, Auteur ; Jørn OLSEN, Auteur ; Sanni BREINING, Auteur ; Jiong LI, Auteur ; Therese K. GRØNBORG, Auteur ; Mika GISSLER, Auteur ; Michael RUTTER, Auteur . - p.532-537.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.532-537
Mots-clés : Smoking pregnancy attention deficit hyperactivity disorder hyperkinetic disorder sibling design Index. décimale : PER Périodiques Résumé : Background Conventional cohort studies have consistently shown that exposure to maternal smoking in pregnancy is associated with about twice the risk of attention deficit hyperactivity disorder (ADHD) in the offspring. However, recent studies using alternative designs to disentangle the effect of social and genetic confounders have suggested that confounding may account for the association. In this study we aimed to estimate the association by a sibling design. Methods We used a design with half and full siblings in a Danish national register-based cohort on all singletons born between January 1991 and December 2006 and followed until January 2011. Data were available for 90% (N = 968,665) of the singleton live births in the period. We used the combination of the International Classification of Diseases (10th version) diagnosis of hyperkinetic disorder (HKD) and ADHD medication to identify children. We used sibling-matched (conditional) Cox regression to control social and genetic confounding. Results Using conventional cohort analyses, we found the expected association between pregnancy smoking and offspring ADHD (adjusted HR 2.01, 95% CI 1.94–2.07). In the sibling analysis, however, we did not detect such a strong association (adjusted HR 1.07, 95% CI 0.94–1.22). There was no difference between results for half- and full sibling analyses. The link between pregnancy smoking and low birth weight remained robust in the sibling design (adjusted OR 1.68, 95% CI 1.33–2.12). Conclusions We found no support for prenatal smoking as a strong causal factor in ADHD. Our findings suggest that the strong association found in most previous epidemiological studies is likely to be due to a strong link between maternal smoking and maternal ADHD genetics or shared family environment. Pregnant women should still be encouraged to stop smoking because of other risks, but we have no reason to believe that this would reduce the risk of ADHD in the offspring. En ligne : http://dx.doi.org/10.1111/jcpp.12478 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285 A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders / Hjördis Osk ATLADOTTIR in Journal of Autism and Developmental Disorders, 45-8 (August 2015)
[article]
Titre : A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Erik T. PARNER, Auteur ; T. B. HENRIKSEN, Auteur Année de publication : 2015 Article en page(s) : p.2429-2442 Langues : Anglais (eng) Mots-clés : Autism Neonatal Hyperkinetic disorder CP Epilepsy Intellectual disability Index. décimale : PER Périodiques Résumé : The aim of this study was to describe the profile of specific neonatal morbidities in children later diagnosed with autism spectrum disorder (ASD), and to compare this profile with the profile of children with hyperkinetic disorder, cerebral palsy, epilepsy or intellectual disability. This is a Danish population based cohort study, including all children born in Denmark from 1994, through 2010, and surviving the first year of life. Children with ASD as a whole have significantly elevated rates of a range of neurologic, respiratory, inflammatory, and metabolic problems in the neonatal period compared to the general population, but there are few if any indicators of a distinctive neonatal morbidity profile in ASD compared to other neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1007/s10803-015-2408-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263
in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2429-2442[article] A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders [Texte imprimé et/ou numérique] / Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Erik T. PARNER, Auteur ; T. B. HENRIKSEN, Auteur . - 2015 . - p.2429-2442.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2429-2442
Mots-clés : Autism Neonatal Hyperkinetic disorder CP Epilepsy Intellectual disability Index. décimale : PER Périodiques Résumé : The aim of this study was to describe the profile of specific neonatal morbidities in children later diagnosed with autism spectrum disorder (ASD), and to compare this profile with the profile of children with hyperkinetic disorder, cerebral palsy, epilepsy or intellectual disability. This is a Danish population based cohort study, including all children born in Denmark from 1994, through 2010, and surviving the first year of life. Children with ASD as a whole have significantly elevated rates of a range of neurologic, respiratory, inflammatory, and metabolic problems in the neonatal period compared to the general population, but there are few if any indicators of a distinctive neonatal morbidity profile in ASD compared to other neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1007/s10803-015-2408-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263