Documents disponibles écrits par cet auteur

Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism / Mayada ELSABBAGH in Journal of Autism and Developmental Disorders, 45-2 (February 2015) 

Public ISBD [article]  in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291 Titre : Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism Type de document : texte imprimé Auteurs : Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur Article en page(s) : p.283-291 Langues : Anglais (eng) Mots-clés : Infant  Autism  Interaction  EEG  Familial risk  Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2583 [article] Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism [texte imprimé] / Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur . - p.283-291. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291 Mots-clés : Infant  Autism  Interaction  EEG  Familial risk  Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2583

Intervention for Infants at Risk of Developing Autism: A Case Series / Jonathan GREEN in Journal of Autism and Developmental Disorders, 43-11 (November 2013) 

Public ISBD [article]  in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2502-2514 Titre : Intervention for Infants at Risk of Developing Autism: A Case Series Type de document : texte imprimé Auteurs : Jonathan GREEN, Auteur ; Ming Wai WAN, Auteur ; Jeanne GUIRAUD, Auteur ; Samina HOLSGROVE, Auteur ; Janet MCNALLY, Auteur ; Vicky SLONIMS, Auteur ; Mayada ELSABBAGH, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark JOHNSON, Auteur Article en page(s) : p.2502-2514 Langues : Anglais (eng) Mots-clés : Autism  Intervention  Prodromal  Infancy  Parent–child interaction Index. décimale : PER Périodiques Résumé : Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8–10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1797-8 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2172 [article] Intervention for Infants at Risk of Developing Autism: A Case Series [texte imprimé] / Jonathan GREEN, Auteur ; Ming Wai WAN, Auteur ; Jeanne GUIRAUD, Auteur ; Samina HOLSGROVE, Auteur ; Janet MCNALLY, Auteur ; Vicky SLONIMS, Auteur ; Mayada ELSABBAGH, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark JOHNSON, Auteur . - p.2502-2514. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2502-2514 Mots-clés : Autism  Intervention  Prodromal  Infancy  Parent–child interaction Index. décimale : PER Périodiques Résumé : Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8–10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1797-8 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2172

Negative and atypical story content themes depicted by children with behaviour problems / Ming Wai WAN in Journal of Child Psychology and Psychiatry, 51-10 (October 2010) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 51-10 (October 2010) . - p.1125-1131 Titre : Negative and atypical story content themes depicted by children with behaviour problems Type de document : texte imprimé Auteurs : Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur Article en page(s) : p.1125-1131 Langues : Anglais (eng) Mots-clés : Conduct-disorder maternal-depression doll-play mother–child-relations story-stems Index. décimale : PER Périodiques Résumé : Keywords:Conduct disorder;maternal depression;doll play;mother–child relations;story stems Background:  Specific thematic content arising from children’s doll play is often considered to give clinically meaningful information regarding their mental state, but has received little systematic enquiry. This exploratory study examined the negative and atypical content themes in the attachment story narratives of children with behaviour problems, and their associations with child symptomatology and parental depressed mood. Method:  Videotaped mother–child attachment doll play completions of 77 children from a clinical sample were blind coded for negative content themes. Mothers completed questionnaires for maternal depression and child behaviour. Results:  Children rating positive for behaviour disorder were more likely to represent maternal injury, role reversal and marked maternal sadness. Severe behavioural symptoms were associated with more pervasive negative themes. Half of the overall sample depicted child accidents and maternal unresponsiveness, whereas child aggression, child anger and maternal absence were rare. Girls with depressed mothers showed an absence of particular negative representations (e.g., child sadness) compared to boys. Conclusions:  Specific atypical themes are associated with the extent of child psychopathology and may be modified by exposure to maternal depressed mood. The methodological limitations in this exploratory study are also discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02239.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1105 [article] Negative and atypical story content themes depicted by children with behaviour problems [texte imprimé] / Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur . - p.1125-1131. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 51-10 (October 2010) . - p.1125-1131 Mots-clés : Conduct-disorder maternal-depression doll-play mother–child-relations story-stems Index. décimale : PER Périodiques Résumé : Keywords:Conduct disorder;maternal depression;doll play;mother–child relations;story stems Background:  Specific thematic content arising from children’s doll play is often considered to give clinically meaningful information regarding their mental state, but has received little systematic enquiry. This exploratory study examined the negative and atypical content themes in the attachment story narratives of children with behaviour problems, and their associations with child symptomatology and parental depressed mood. Method:  Videotaped mother–child attachment doll play completions of 77 children from a clinical sample were blind coded for negative content themes. Mothers completed questionnaires for maternal depression and child behaviour. Results:  Children rating positive for behaviour disorder were more likely to represent maternal injury, role reversal and marked maternal sadness. Severe behavioural symptoms were associated with more pervasive negative themes. Half of the overall sample depicted child accidents and maternal unresponsiveness, whereas child aggression, child anger and maternal absence were rare. Girls with depressed mothers showed an absence of particular negative representations (e.g., child sadness) compared to boys. Conclusions:  Specific atypical themes are associated with the extent of child psychopathology and may be modified by exposure to maternal depressed mood. The methodological limitations in this exploratory study are also discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02239.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1105

Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome / Ming Wai WAN in Journal of Child Psychology and Psychiatry, 54-7 (July 2013) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771 Titre : Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome Type de document : texte imprimé Auteurs : Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team the, Auteur Article en page(s) : p.763-771 Langues : Anglais (eng) Mots-clés : ASD siblings  mother–child relations  high-risk infants  parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2031 [article] Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome [texte imprimé] / Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team the, Auteur . - p.763-771. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771 Mots-clés : ASD siblings  mother–child relations  high-risk infants  parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2031

Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years / Jonathan GREEN in Journal of Child Psychology and Psychiatry, 58-12 (December 2017) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1330-1340 Titre : Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years Type de document : texte imprimé Auteurs : Jonathan GREEN, Auteur ; Andrew PICKLES, Auteur ; Greg PASCO, Auteur ; Rachael BEDFORD, Auteur ; Ming Wai WAN, Auteur ; Mayada ELSABBAGH, Auteur ; Vicky SLONIMS, Auteur ; Teea GLIGA, Auteur ; Emily JONES, Auteur ; Celeste CHEUNG, Auteur ; Tony CHARMAN, Auteur ; Mark JOHNSON, Auteur ; Team THE BRITISH AUTISM STUDY OF INFANT SIBLINGS, Auteur Article en page(s) : p.1330-1340 Langues : Anglais (eng) Mots-clés : Pre-emptive intervention  prevention trials  autism  autism spectrum disorder  high-risk siblings  parent-mediated intervention Index. décimale : PER Périodiques Résumé : Background There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. Methods A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention. Fifty-four infants (28 intervention, 26 nonintervention) at familial risk of autism but not otherwise selected for developmental atypicality were assessed at 9-month baseline, 15-month treatment endpoint, and 27- and 39-month follow-up. Primary outcome: severity of autism prodromal symptoms, blind-rated on Autism Observation Schedule for Infants or Autism Diagnostic Observation Schedule 2nd Edition across the four assessment points. Secondary outcomes: blind-rated parent–child interaction and child language; nonblind parent-rated communication and socialisation. Prespecified intention-to-treat analysis combined estimates from repeated measures within correlated regressions to estimate the overall effect of the infancy intervention over time. Results Effect estimates in favour of intervention on autism prodromal symptoms, maximal at 27 months, had confidence intervals (CIs) at each separate time point including the null, but showed a significant overall effect over the course of the intervention and follow-up period (effect size [ES] = 0.32; 95% CI 0.04, 0.60; p = .026). Effects on proximal intervention targets of parent nondirectiveness/synchrony (ES = 0.33; CI 0.04, 0.63; p = .013) and child attentiveness/communication initiation (ES = 0.36; 95% CI 0.04, 0.68; p = .015) showed similar results. There was no effect on categorical diagnostic outcome or formal language measures. Conclusions Follow-up to 3 years of the first RCT of a very early social communication intervention for infants at familial risk of developing autism has shown a treatment effect, extending 24 months after intervention end, to reduce the overall severity of autism prodromal symptoms and enhance parent–child dyadic social communication over this period. We highlight the value of extended follow-up and repeat assessment for early intervention trials. En ligne : http://dx.doi.org/10.1111/jcpp.12728 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3268 [article] Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years [texte imprimé] / Jonathan GREEN, Auteur ; Andrew PICKLES, Auteur ; Greg PASCO, Auteur ; Rachael BEDFORD, Auteur ; Ming Wai WAN, Auteur ; Mayada ELSABBAGH, Auteur ; Vicky SLONIMS, Auteur ; Teea GLIGA, Auteur ; Emily JONES, Auteur ; Celeste CHEUNG, Auteur ; Tony CHARMAN, Auteur ; Mark JOHNSON, Auteur ; Team THE BRITISH AUTISM STUDY OF INFANT SIBLINGS, Auteur . - p.1330-1340. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1330-1340 Mots-clés : Pre-emptive intervention  prevention trials  autism  autism spectrum disorder  high-risk siblings  parent-mediated intervention Index. décimale : PER Périodiques Résumé : Background There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. Methods A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention. Fifty-four infants (28 intervention, 26 nonintervention) at familial risk of autism but not otherwise selected for developmental atypicality were assessed at 9-month baseline, 15-month treatment endpoint, and 27- and 39-month follow-up. Primary outcome: severity of autism prodromal symptoms, blind-rated on Autism Observation Schedule for Infants or Autism Diagnostic Observation Schedule 2nd Edition across the four assessment points. Secondary outcomes: blind-rated parent–child interaction and child language; nonblind parent-rated communication and socialisation. Prespecified intention-to-treat analysis combined estimates from repeated measures within correlated regressions to estimate the overall effect of the infancy intervention over time. Results Effect estimates in favour of intervention on autism prodromal symptoms, maximal at 27 months, had confidence intervals (CIs) at each separate time point including the null, but showed a significant overall effect over the course of the intervention and follow-up period (effect size [ES] = 0.32; 95% CI 0.04, 0.60; p = .026). Effects on proximal intervention targets of parent nondirectiveness/synchrony (ES = 0.33; CI 0.04, 0.63; p = .013) and child attentiveness/communication initiation (ES = 0.36; 95% CI 0.04, 0.68; p = .015) showed similar results. There was no effect on categorical diagnostic outcome or formal language measures. Conclusions Follow-up to 3 years of the first RCT of a very early social communication intervention for infants at familial risk of developing autism has shown a treatment effect, extending 24 months after intervention end, to reduce the overall severity of autism prodromal symptoms and enhance parent–child dyadic social communication over this period. We highlight the value of extended follow-up and repeat assessment for early intervention trials. En ligne : http://dx.doi.org/10.1111/jcpp.12728 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3268

Subgroups of Temperament Associated with Social-Emotional Difficulties in Infants with Early Signs of Autism / Lacey CHETCUTI in Autism Research, 13-12 (December 2020) 

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The Role of Negative Affectivity in Concurrent Relations Between Caregiver Psychological Distress and Social-Emotional Difficulties in Infants With Early Signs of Autism / Lacey CHETCUTI in Autism Research, 13-8 (August 2020) 

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