Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults / Jinni SU in Development and Psychopathology, 36-4 (October 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-4 (October 2024) . - p.1763-1775 Titre : Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults Type de document : Texte imprimé et/ou numérique Auteurs : Jinni SU, Auteur ; Sally I. Chun KUO, Auteur ; Fazil ALIEV, Auteur ; Jill A. RABINOWITZ, Auteur ; Belal JAMIL, Auteur ; Grace CHAN, Auteur ; Howard J. EDENBERG, Auteur ; Meredith FRANCIS, Auteur ; Victor HESSELBROCK, Auteur ; Chella KAMARAJAN, Auteur ; Sivan KINREICH, Auteur ; John KRAMER, Auteur ; Donbing LAI, Auteur ; Vivia MCCUTCHEON, Auteur ; Jacquelyn MEYERS, Auteur ; Ashwini PANDEY, Auteur ; Gayathri PANDEY, Auteur ; Martin H. PLAWECKI, Auteur ; Marc SCHUCKIT, Auteur ; Jay TISCHFIELD, Auteur ; Danielle M. DICK, Auteur Article en page(s) : p.1763-1775 Langues : Anglais (eng) Mots-clés : COGA  alcohol use  gene-environment interaction  polygenic scores  social support Index. décimale : PER Périodiques Résumé : Alcohol use is influenced by genetic and environmental factors. We examined the interactive effects between genome-wide polygenic risk scores for alcohol use (alc-PRS) and social support in relation to alcohol use among European American (EA) and African American (AA) adults across sex and developmental stages (emerging adulthood, young adulthood, and middle adulthood). Data were drawn from 4,011 EA and 1,274 AA adults from the Collaborative Study on the Genetics of Alcoholism who were between ages 18-65 and had ever used alcohol. Participants completed the Semi-Structured Assessment for the Genetics of Alcoholism and provided saliva or blood samples for genotyping. Results indicated that social support from friends, but not family, moderated the association between alc-PRS and alcohol use among EAs and AAs (only in middle adulthood for AAs); alc-PRS was associated with higher levels of alcohol use when friend support was low, but not when friend support was high. Associations were similar across sex but differed across developmental stages. Findings support the important role of social support from friends in buffering genetic risk for alcohol use among EA and AA adults and highlight the need to consider developmental changes in the role of social support in relation to alcohol use. En ligne : https://dx.doi.org/10.1017/S0954579423001141 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539 [article] Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults [Texte imprimé et/ou numérique] / Jinni SU, Auteur ; Sally I. Chun KUO, Auteur ; Fazil ALIEV, Auteur ; Jill A. RABINOWITZ, Auteur ; Belal JAMIL, Auteur ; Grace CHAN, Auteur ; Howard J. EDENBERG, Auteur ; Meredith FRANCIS, Auteur ; Victor HESSELBROCK, Auteur ; Chella KAMARAJAN, Auteur ; Sivan KINREICH, Auteur ; John KRAMER, Auteur ; Donbing LAI, Auteur ; Vivia MCCUTCHEON, Auteur ; Jacquelyn MEYERS, Auteur ; Ashwini PANDEY, Auteur ; Gayathri PANDEY, Auteur ; Martin H. PLAWECKI, Auteur ; Marc SCHUCKIT, Auteur ; Jay TISCHFIELD, Auteur ; Danielle M. DICK, Auteur . - p.1763-1775. Langues : Anglais (eng) in Development and Psychopathology > 36-4 (October 2024) . - p.1763-1775 Mots-clés : COGA  alcohol use  gene-environment interaction  polygenic scores  social support Index. décimale : PER Périodiques Résumé : Alcohol use is influenced by genetic and environmental factors. We examined the interactive effects between genome-wide polygenic risk scores for alcohol use (alc-PRS) and social support in relation to alcohol use among European American (EA) and African American (AA) adults across sex and developmental stages (emerging adulthood, young adulthood, and middle adulthood). Data were drawn from 4,011 EA and 1,274 AA adults from the Collaborative Study on the Genetics of Alcoholism who were between ages 18-65 and had ever used alcohol. Participants completed the Semi-Structured Assessment for the Genetics of Alcoholism and provided saliva or blood samples for genotyping. Results indicated that social support from friends, but not family, moderated the association between alc-PRS and alcohol use among EAs and AAs (only in middle adulthood for AAs); alc-PRS was associated with higher levels of alcohol use when friend support was low, but not when friend support was high. Associations were similar across sex but differed across developmental stages. Findings support the important role of social support from friends in buffering genetic risk for alcohol use among EA and AA adults and highlight the need to consider developmental changes in the role of social support in relation to alcohol use. En ligne : https://dx.doi.org/10.1017/S0954579423001141 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples / Kit K. ELAM in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.82-91 Titre : Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples Type de document : Texte imprimé et/ou numérique Auteurs : Kit K. ELAM, Auteur ; Kaitlin E. BOUNTRESS, Auteur ; Thao HA, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Fazil ALIEV, Auteur ; Danielle M. DICK, Auteur ; Kathryn LEMERY-CHALFANT, Auteur Article en page(s) : p.82-91 Langues : Anglais (eng) Mots-clés : adolescence  alcohol use  externalizing  longitudinal  polygenic Index. décimale : PER Périodiques Résumé : Externalizing behavior in early adolescence is associated with alcohol use in adolescence and early adulthood and these behaviors often emerge as part of a developmental sequence. This pattern can be the result of heterotypic continuity, in which different behaviors emerge over time based on an underlying shared etiology. In particular, there is largely a shared genetic etiology underlying externalizing and substance use behaviors. We examined whether polygenic risk for alcohol use disorder predicted (1) externalizing behavior in early adolescence and alcohol use in adolescence in the Early Steps Multisite sample and (2) externalizing behavior in adolescence and alcohol use in early adulthood in the Project Alliance 1 (PAL1) sample. We examined associations separately for African Americans and European Americans. When examining European Americans in the Early Steps sample, greater polygenic risk was associated with externalizing behavior in early adolescence. In European Americans in PAL1, we found greater polygenic risk was associated with alcohol use in early adulthood. Effects were largely absent in African Americans in both samples. Results imply that genetic predisposition for alcohol use disorder may increase risk for externalizing and alcohol use as these behaviors emerge developmentally. En ligne : https://dx.doi.org/10.1017/S0954579422000980 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples [Texte imprimé et/ou numérique] / Kit K. ELAM, Auteur ; Kaitlin E. BOUNTRESS, Auteur ; Thao HA, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Fazil ALIEV, Auteur ; Danielle M. DICK, Auteur ; Kathryn LEMERY-CHALFANT, Auteur . - p.82-91. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.82-91 Mots-clés : adolescence  alcohol use  externalizing  longitudinal  polygenic Index. décimale : PER Périodiques Résumé : Externalizing behavior in early adolescence is associated with alcohol use in adolescence and early adulthood and these behaviors often emerge as part of a developmental sequence. This pattern can be the result of heterotypic continuity, in which different behaviors emerge over time based on an underlying shared etiology. In particular, there is largely a shared genetic etiology underlying externalizing and substance use behaviors. We examined whether polygenic risk for alcohol use disorder predicted (1) externalizing behavior in early adolescence and alcohol use in adolescence in the Early Steps Multisite sample and (2) externalizing behavior in adolescence and alcohol use in early adulthood in the Project Alliance 1 (PAL1) sample. We examined associations separately for African Americans and European Americans. When examining European Americans in the Early Steps sample, greater polygenic risk was associated with externalizing behavior in early adolescence. In European Americans in PAL1, we found greater polygenic risk was associated with alcohol use in early adulthood. Effects were largely absent in African Americans in both samples. Results imply that genetic predisposition for alcohol use disorder may increase risk for externalizing and alcohol use as these behaviors emerge developmentally. En ligne : https://dx.doi.org/10.1017/S0954579422000980 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins / Jeanne E. SAVAGE in Development and Psychopathology, 30-1 (February 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-1 (February 2018) . - p.79-92 Titre : Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins Type de document : Texte imprimé et/ou numérique Auteurs : Jeanne E. SAVAGE, Auteur ; Richard J. ROSE, Auteur ; Lea PULKKINEN, Auteur ; Karri SILVENTOINEN, Auteur ; Tellervo KORHONEN, Auteur ; Jaakko KAPRIO, Auteur ; Nathan GILLESPIE, Auteur ; Danielle M. DICK, Auteur Article en page(s) : p.79-92 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Early maturation, indexed by pubertal development (PD), has been associated with earlier initiation and greater frequency of adolescent substance use, but this relationship may be biased by confounding factors and effects that change across development. Using a population-based Finnish twin sample (N = 3,632 individuals), we conducted twin modeling and multilevel structural equation modeling of the relationship between PD and substance use at ages 12–22. Shared environmental factors contributed to early PD and heavier substance use for females. Biological father absence was associated with early PD for boys but not girls, and did not account for the relationship between PD and substance use. The association between early PD and heavier substance use was partially due to between-family confounds, although early PD appeared to qualitatively alter long-term trajectories for some substances (nicotine), but not others (alcohol). Mediation by peer and parental factors did not explain this relationship within families. However, higher peer substance use and lower parental monitoring were themselves associated with heavier substance use, strengthening the existing evidence for these factors as targets for prevention/intervention efforts. Early maturation was not supported as a robust determinant of alcohol use trajectories in adolescence and young adulthood, but may require longer term follow-up. Subtle effects of early PD on nicotine and illicit drug use trajectories throughout adolescence and adulthood merit further investigation. En ligne : https://doi.org/10.1017/S0954579417000487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=335 [article] Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins [Texte imprimé et/ou numérique] / Jeanne E. SAVAGE, Auteur ; Richard J. ROSE, Auteur ; Lea PULKKINEN, Auteur ; Karri SILVENTOINEN, Auteur ; Tellervo KORHONEN, Auteur ; Jaakko KAPRIO, Auteur ; Nathan GILLESPIE, Auteur ; Danielle M. DICK, Auteur . - p.79-92. Langues : Anglais (eng) in Development and Psychopathology > 30-1 (February 2018) . - p.79-92 Index. décimale : PER Périodiques Résumé : Early maturation, indexed by pubertal development (PD), has been associated with earlier initiation and greater frequency of adolescent substance use, but this relationship may be biased by confounding factors and effects that change across development. Using a population-based Finnish twin sample (N = 3,632 individuals), we conducted twin modeling and multilevel structural equation modeling of the relationship between PD and substance use at ages 12–22. Shared environmental factors contributed to early PD and heavier substance use for females. Biological father absence was associated with early PD for boys but not girls, and did not account for the relationship between PD and substance use. The association between early PD and heavier substance use was partially due to between-family confounds, although early PD appeared to qualitatively alter long-term trajectories for some substances (nicotine), but not others (alcohol). Mediation by peer and parental factors did not explain this relationship within families. However, higher peer substance use and lower parental monitoring were themselves associated with heavier substance use, strengthening the existing evidence for these factors as targets for prevention/intervention efforts. Early maturation was not supported as a robust determinant of alcohol use trajectories in adolescence and young adulthood, but may require longer term follow-up. Subtle effects of early PD on nicotine and illicit drug use trajectories throughout adolescence and adulthood merit further investigation. En ligne : https://doi.org/10.1017/S0954579417000487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=335

Examining interactions between genetic risk for alcohol problems, peer deviance, and interpersonal traumatic events on trajectories of alcohol use disorder symptoms among African American college students / Jinni SU in Development and Psychopathology, 30-5 (December 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-5 (December 2018) . - p.1749-1761 Titre : Examining interactions between genetic risk for alcohol problems, peer deviance, and interpersonal traumatic events on trajectories of alcohol use disorder symptoms among African American college students Type de document : Texte imprimé et/ou numérique Auteurs : Jinni SU, Auteur ; Sally I. Chun KUO, Auteur ; Jacquelyn L. MEYERS, Auteur ; Mignonne C. GUY, Auteur ; Danielle M. DICK, Auteur Article en page(s) : p.1749-1761 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Numerous studies have demonstrated that genetic and environmental factors interact to influence alcohol problems. Yet prior research has primarily focused on samples of European descent and little is known about gene–environment interactions in relation to alcohol problems in non-European populations. In this study, we examined whether and how genetic risk for alcohol problems and peer deviance and interpersonal traumatic events independently and interactively influence trajectories of alcohol use disorder symptoms in a sample of African American students across the college years (N = 1,119; Mage = 18.44 years). Data were drawn from the Spit for Science study where participants completed multiple online surveys throughout college and provided a saliva sample for genotyping. Multilevel growth curve analyses indicated that alcohol dependence genome-wide polygenic risk scores did not predict trajectory of alcohol use disorder symptoms, while family history of alcohol problems was associated with alcohol use disorder symptoms at the start of college but not with the rate of change in symptoms over time. Peer deviance and interpersonal traumatic events were associated with more alcohol use disorder symptoms across college years. Neither alcohol dependence genome-wide polygenic risk scores nor family history of alcohol problems moderated the effects of these environmental risk factors on alcohol use disorder symptoms. Our findings indicated that peer deviance and experience of interpersonal traumatic events are salient risk factors that elevate risk for alcohol problems among African American college students. Family history of alcohol problems could be a useful indicator of genetic risk for alcohol problems. Gene identification efforts with much larger samples of African descent are needed to better characterize genetic risk for alcohol use disorders, in order to better understand gene–environment interaction processes in this understudied population. En ligne : http://dx.doi.org/10.1017/S0954579418000962 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Examining interactions between genetic risk for alcohol problems, peer deviance, and interpersonal traumatic events on trajectories of alcohol use disorder symptoms among African American college students [Texte imprimé et/ou numérique] / Jinni SU, Auteur ; Sally I. Chun KUO, Auteur ; Jacquelyn L. MEYERS, Auteur ; Mignonne C. GUY, Auteur ; Danielle M. DICK, Auteur . - p.1749-1761. Langues : Anglais (eng) in Development and Psychopathology > 30-5 (December 2018) . - p.1749-1761 Index. décimale : PER Périodiques Résumé : Numerous studies have demonstrated that genetic and environmental factors interact to influence alcohol problems. Yet prior research has primarily focused on samples of European descent and little is known about gene–environment interactions in relation to alcohol problems in non-European populations. In this study, we examined whether and how genetic risk for alcohol problems and peer deviance and interpersonal traumatic events independently and interactively influence trajectories of alcohol use disorder symptoms in a sample of African American students across the college years (N = 1,119; Mage = 18.44 years). Data were drawn from the Spit for Science study where participants completed multiple online surveys throughout college and provided a saliva sample for genotyping. Multilevel growth curve analyses indicated that alcohol dependence genome-wide polygenic risk scores did not predict trajectory of alcohol use disorder symptoms, while family history of alcohol problems was associated with alcohol use disorder symptoms at the start of college but not with the rate of change in symptoms over time. Peer deviance and interpersonal traumatic events were associated with more alcohol use disorder symptoms across college years. Neither alcohol dependence genome-wide polygenic risk scores nor family history of alcohol problems moderated the effects of these environmental risk factors on alcohol use disorder symptoms. Our findings indicated that peer deviance and experience of interpersonal traumatic events are salient risk factors that elevate risk for alcohol problems among African American college students. Family history of alcohol problems could be a useful indicator of genetic risk for alcohol problems. Gene identification efforts with much larger samples of African descent are needed to better characterize genetic risk for alcohol use disorders, in order to better understand gene–environment interaction processes in this understudied population. En ligne : http://dx.doi.org/10.1017/S0954579418000962 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

A longitudinal study examining the associations between interpersonal trauma and romantic relationships among college students / Rebecca L. SMITH in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1346-1357 Titre : A longitudinal study examining the associations between interpersonal trauma and romantic relationships among college students Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca L. SMITH, Auteur ; Danielle M. DICK, Auteur ; Ananda AMSTADTER, Auteur ; Nathaniel THOMAS, Auteur ; Jessica E. SALVATORE, Auteur Article en page(s) : p.1346-1357 Langues : Anglais (eng) Mots-clés : college students  emerging adulthood  interpersonal trauma  romantic relationships Index. décimale : PER Périodiques Résumé : We examined the associations between the developmental timing of interpersonal trauma exposure (IPT) and three indicators of involvement in and quality of romantic relationships in emerging adulthood: relationship status, relationship satisfaction, and partner alcohol use. We further examined whether these associations varied in a sex-specific manner. In a sample of emerging adult college students (N = 12,358; 61.5% female) assessed longitudinally across the college years, we found precollege IPT increased the likelihood of being in a relationship, while college-onset IPT decreased the likelihood. Precollege and college-onset IPT predicted lower relationship satisfaction, and college-onset IPT predicted higher partner alcohol use. There was no evidence that associations between IPT and relationship characteristics varied in a sex-specific manner. Findings indicate that IPT exposure, and the developmental timing of IPT, may affect college students' relationship status. Findings also suggest that IPT affects their ability to form satisfying relationships with prosocial partners. En ligne : http://dx.doi.org/10.1017/S0954579421001243 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] A longitudinal study examining the associations between interpersonal trauma and romantic relationships among college students [Texte imprimé et/ou numérique] / Rebecca L. SMITH, Auteur ; Danielle M. DICK, Auteur ; Ananda AMSTADTER, Auteur ; Nathaniel THOMAS, Auteur ; Jessica E. SALVATORE, Auteur . - p.1346-1357. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1346-1357 Mots-clés : college students  emerging adulthood  interpersonal trauma  romantic relationships Index. décimale : PER Périodiques Résumé : We examined the associations between the developmental timing of interpersonal trauma exposure (IPT) and three indicators of involvement in and quality of romantic relationships in emerging adulthood: relationship status, relationship satisfaction, and partner alcohol use. We further examined whether these associations varied in a sex-specific manner. In a sample of emerging adult college students (N = 12,358; 61.5% female) assessed longitudinally across the college years, we found precollege IPT increased the likelihood of being in a relationship, while college-onset IPT decreased the likelihood. Precollege and college-onset IPT predicted lower relationship satisfaction, and college-onset IPT predicted higher partner alcohol use. There was no evidence that associations between IPT and relationship characteristics varied in a sex-specific manner. Findings indicate that IPT exposure, and the developmental timing of IPT, may affect college students' relationship status. Findings also suggest that IPT affects their ability to form satisfying relationships with prosocial partners. En ligne : http://dx.doi.org/10.1017/S0954579421001243 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

MAOA-uVNTR and early physical discipline interact to influence delinquent behavior / Michael C. EDWARDS in Journal of Child Psychology and Psychiatry, 51-6 (June 2010)  

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Mapping potential pathways from polygenic liability through brain structure to psychological problems across the transition to adolescence / E. Leighton DURHAM ; Sarah J. BRISLIN ; Peter B. BARR ; Danielle M. DICK ; Tyler M. MOORE ; Brandon L. PIERCE ; Lin TONG ; Gabrielle E. REIMANN ; Hee Jung JEONG ; Randolph M. DUPONT ; Antonia N. KACZKURKIN in Journal of Child Psychology and Psychiatry, 65-8 (August 2024)  

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Parental Socialization and Adolescents'Alcohol Use Behaviors: Predictive Disparities in Parents'Versus Adolescents'Perceptions of the Parenting Environment / Shawn J. LATENDRESSE in Journal of Clinical Child & Adolescent Psychology, 38-2 (March-April 2009)  

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A systematic review of gene-by-intervention studies of alcohol and other substance use / Zoe E. NEALE in Development and Psychopathology, 33-4 (October 2021)  

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The role of parental genotype in the intergenerational transmission of externalizing behavior: Evidence for genetic nurturance / Sally I. Chun KUO in Development and Psychopathology, 34-5 (December 2022)  

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Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk / Seung Bin CHO in Development and Psychopathology, 33-3 (August 2021)  

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Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk – CORRIGENDUM / Seung Bin CHO in Development and Psychopathology, 34-3 (August 2022)  

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