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Auteur David A. AXELSON |
Documents disponibles écrits par cet auteur (7)



A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder / C. J. R. SEWALL in Journal of Child Psychology and Psychiatry, 62-7 (July 2021)
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Titre : A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : C. J. R. SEWALL, Auteur ; J. M. GIRARD, Auteur ; J. MERRANKO, Auteur ; D. HAFEMAN, Auteur ; B. I. GOLDSTEIN, Auteur ; M. STROBER, Auteur ; H. HOWER, Auteur ; L. M. WEINSTOCK, Auteur ; S. YEN, Auteur ; N. D. RYAN, Auteur ; M. B. KELLER, Auteur ; F. LIAO, Auteur ; Rasim S. DILER, Auteur ; M. KAY GILL, Auteur ; David A. AXELSON, Auteur ; Boris BIRMAHER, Auteur ; Tina R. GOLDSTEIN, Auteur Article en page(s) : p.905-915 Langues : Anglais (eng) Mots-clés : Adolescent Bayes Theorem Bipolar Disorder/epidemiology Humans Multilevel Analysis Risk Factors Suicidal Ideation Suicide, Attempted Bayesian analysis Suicide adolescence bipolar disorder parent-child relationships peer relationships Index. décimale : PER Périodiques Résumé : BACKGROUND: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between-person differences - reflecting the average relationship quality across time - and within-person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. METHODS: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. RESULTS: Poorer average relationship quality with parents (? = -.33, 95% Bayesian highest density interval (HDI) [-0.54, -0.11]) or friends (? = -.33, 95% HDI [-0.55, -0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (? = -.10, 95% HDI [-0.19, -0.03]) and, to a lesser extent, friends (? = -.06, 95% HDI [-0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (? = -.15, 95% HDI [-0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. CONCLUSIONS: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time-sensitive indicator of increased risk for SI or suicide attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.905-915[article] A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder [Texte imprimé et/ou numérique] / C. J. R. SEWALL, Auteur ; J. M. GIRARD, Auteur ; J. MERRANKO, Auteur ; D. HAFEMAN, Auteur ; B. I. GOLDSTEIN, Auteur ; M. STROBER, Auteur ; H. HOWER, Auteur ; L. M. WEINSTOCK, Auteur ; S. YEN, Auteur ; N. D. RYAN, Auteur ; M. B. KELLER, Auteur ; F. LIAO, Auteur ; Rasim S. DILER, Auteur ; M. KAY GILL, Auteur ; David A. AXELSON, Auteur ; Boris BIRMAHER, Auteur ; Tina R. GOLDSTEIN, Auteur . - p.905-915.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-7 (July 2021) . - p.905-915
Mots-clés : Adolescent Bayes Theorem Bipolar Disorder/epidemiology Humans Multilevel Analysis Risk Factors Suicidal Ideation Suicide, Attempted Bayesian analysis Suicide adolescence bipolar disorder parent-child relationships peer relationships Index. décimale : PER Périodiques Résumé : BACKGROUND: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between-person differences - reflecting the average relationship quality across time - and within-person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. METHODS: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. RESULTS: Poorer average relationship quality with parents (? = -.33, 95% Bayesian highest density interval (HDI) [-0.54, -0.11]) or friends (? = -.33, 95% HDI [-0.55, -0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (? = -.10, 95% HDI [-0.19, -0.03]) and, to a lesser extent, friends (? = -.06, 95% HDI [-0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (? = -.15, 95% HDI [-0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. CONCLUSIONS: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time-sensitive indicator of increased risk for SI or suicide attempt. En ligne : http://dx.doi.org/10.1111/jcpp.13343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Criterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjects / William BURLESON DAVISS in Journal of Child Psychology and Psychiatry, 47-9 (September 2006)
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Titre : Criterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjects Type de document : Texte imprimé et/ou numérique Auteurs : William BURLESON DAVISS, Auteur ; David A. BRENT, Auteur ; Boris BIRMAHER, Auteur ; Nadine M. MELHEM, Auteur ; David A. AXELSON, Auteur ; Shana M. MICHAELS, Auteur Année de publication : 2006 Article en page(s) : p.927–934 Langues : Anglais (eng) Mots-clés : Pediatric-depression assessment validity reliability Index. décimale : PER Périodiques Résumé : Background: Previous measures of pediatric depression have shown inconsistent validity in groups with differing demographics, comorbid diagnoses, and clinic or non-clinic origins. The current study re-examines the criterion validity of child- and parent-versions of the Mood and Feelings Questionnaire (MFQ-C, MFQ-P) in a heterogeneous sample of children and adolescents from clinic and non-clinic sources.
Methods: Among 470 consecutive youth completing semi-structured interviews at a university-based child psychiatry center, total scores from the 33-item MFQ-C and 34-item MFQ-P were examined across subjects with and without mood disorders using analysis of variance, and receiver operating characteristics analysis.
Results: Mean scores of the MFQ-C and MFQ-P, respectively, differed significantly (p < .0005) across youth having major depressive episodes (MDE) (33 and 32, n = 77), mood disorders not meeting criteria for current MDE (24 and 28, n = 75), and no mood disorders (12 and 10, n = 318). In the overall sample, areas under the curve (AUC) for discriminating MDE and any mood disorder, respectively, were .85 and .83 on the MFQ-C, .86 and .90 on the MFQ-P, and .89 and .90 on the MFQ-C and MFQ-P averaged together, suggesting moderate to high criterion validity. Similar findings were noted in subgroups divided by age, sex, race, comorbid psychopathology, and clinic or non-clinic origins. AUCs of these MFQ scores compared favorably with those of the Beck's Depressive Inventory, the Child Behavior Checklist's Anxious/Depressed scale and the Children's Depressive Rating Scale–Revised by the same raters. A score of 29 on the MFQ-C (positive screen rate 21%, sensitivity 68%, specificity 88%) or 27 on the MFQ-P (positive screen rate 23%, sensitivity 61%, specificity 85%) optimally discriminated youth with MDE from the rest of the sample.
Conclusions: The MFQ-C and MFQ-P, especially used in combination, validly identify MDE or other mood disorders in youth diverse in demographic and clinical characteristics.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01646.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=779
in Journal of Child Psychology and Psychiatry > 47-9 (September 2006) . - p.927–934[article] Criterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjects [Texte imprimé et/ou numérique] / William BURLESON DAVISS, Auteur ; David A. BRENT, Auteur ; Boris BIRMAHER, Auteur ; Nadine M. MELHEM, Auteur ; David A. AXELSON, Auteur ; Shana M. MICHAELS, Auteur . - 2006 . - p.927–934.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 47-9 (September 2006) . - p.927–934
Mots-clés : Pediatric-depression assessment validity reliability Index. décimale : PER Périodiques Résumé : Background: Previous measures of pediatric depression have shown inconsistent validity in groups with differing demographics, comorbid diagnoses, and clinic or non-clinic origins. The current study re-examines the criterion validity of child- and parent-versions of the Mood and Feelings Questionnaire (MFQ-C, MFQ-P) in a heterogeneous sample of children and adolescents from clinic and non-clinic sources.
Methods: Among 470 consecutive youth completing semi-structured interviews at a university-based child psychiatry center, total scores from the 33-item MFQ-C and 34-item MFQ-P were examined across subjects with and without mood disorders using analysis of variance, and receiver operating characteristics analysis.
Results: Mean scores of the MFQ-C and MFQ-P, respectively, differed significantly (p < .0005) across youth having major depressive episodes (MDE) (33 and 32, n = 77), mood disorders not meeting criteria for current MDE (24 and 28, n = 75), and no mood disorders (12 and 10, n = 318). In the overall sample, areas under the curve (AUC) for discriminating MDE and any mood disorder, respectively, were .85 and .83 on the MFQ-C, .86 and .90 on the MFQ-P, and .89 and .90 on the MFQ-C and MFQ-P averaged together, suggesting moderate to high criterion validity. Similar findings were noted in subgroups divided by age, sex, race, comorbid psychopathology, and clinic or non-clinic origins. AUCs of these MFQ scores compared favorably with those of the Beck's Depressive Inventory, the Child Behavior Checklist's Anxious/Depressed scale and the Children's Depressive Rating Scale–Revised by the same raters. A score of 29 on the MFQ-C (positive screen rate 21%, sensitivity 68%, specificity 88%) or 27 on the MFQ-P (positive screen rate 23%, sensitivity 61%, specificity 85%) optimally discriminated youth with MDE from the rest of the sample.
Conclusions: The MFQ-C and MFQ-P, especially used in combination, validly identify MDE or other mood disorders in youth diverse in demographic and clinical characteristics.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01646.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=779 Dimensional psychopathology in preschool offspring of parents with bipolar disorder / Hagai MAOZ in Journal of Child Psychology and Psychiatry, 55-2 (February 2014)
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Titre : Dimensional psychopathology in preschool offspring of parents with bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : Hagai MAOZ, Auteur ; Tina R. GOLDSTEIN, Auteur ; David A. AXELSON, Auteur ; Benjamin I. GOLDSTEIN, Auteur ; Jieyu FAN, Auteur ; Mary Beth HICKEY, Auteur ; Kelly MONK, Auteur ; Dara SAKOLSKY, Auteur ; Rasim S. DILER, Auteur ; David A. BRENT, Auteur ; Satish IYENGAR, Auteur ; David J. KUPFER, Auteur ; Boris BIRMAHER, Auteur Article en page(s) : p.144-153 Langues : Anglais (eng) Mots-clés : BP offspring dimensional psychopathology Index. décimale : PER Périodiques Résumé : Background The purpose of this study is to compare the dimensional psychopathology, as ascertained by parental report, in preschool offspring of parents with bipolar disorder (BP) and offspring of community control parents. Methods 122 preschool offspring (mean age 3.3 years) of 84 parents with BP, with 102 offspring of 65 control parents (36 healthy, 29 with non-BP psychopathology), were evaluated using the Child Behavior Checklist (CBCL), the CBCL-Dysregulation Profile (CBCL-DP), the Early Childhood Inventory (ECI-4), and the Emotionality Activity Sociability (EAS) survey. Teachers' Report Forms (TRF) were available for 51 preschoolers. Results After adjusting for confounders, offspring of parents with BP showed higher scores in the CBCL total, externalizing, somatic, sleep, aggressive, and CBCL-DP subscales; the ECI-4 sleep problem scale; and the EAS total and emotionality scale. The proportion of offspring with CBCL T-scores ?2 SD above the norm was significantly higher on most CBCL subscales and the CBCL-DP in offspring of parents with BP compared to offspring of controls even after excluding offspring with attention deficit hyperactivity disorder and/or oppositional defiant disorder. Compared to offspring of parents with BP-I, offspring of parents with BP-II showed significantly higher scores in total and most CBCL subscales, the ECI-4 anxiety and sleep scales and the EAS emotionality scale. For both groups of parents, there were significant correlations between CBCL and TRF scores (r = .32–.38, p-values ?.02). Conclusions Independent of categorical axis-I psychopathology and other demographic or clinical factors in both biological parents, preschool offspring of parents with BP have significantly greater aggression, mood dysregulation, sleep disturbances, and somatic complaints compared to offspring of control parents. Interventions to target these symptoms are warranted. En ligne : http://dx.doi.org/10.1111/jcpp.12137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.144-153[article] Dimensional psychopathology in preschool offspring of parents with bipolar disorder [Texte imprimé et/ou numérique] / Hagai MAOZ, Auteur ; Tina R. GOLDSTEIN, Auteur ; David A. AXELSON, Auteur ; Benjamin I. GOLDSTEIN, Auteur ; Jieyu FAN, Auteur ; Mary Beth HICKEY, Auteur ; Kelly MONK, Auteur ; Dara SAKOLSKY, Auteur ; Rasim S. DILER, Auteur ; David A. BRENT, Auteur ; Satish IYENGAR, Auteur ; David J. KUPFER, Auteur ; Boris BIRMAHER, Auteur . - p.144-153.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.144-153
Mots-clés : BP offspring dimensional psychopathology Index. décimale : PER Périodiques Résumé : Background The purpose of this study is to compare the dimensional psychopathology, as ascertained by parental report, in preschool offspring of parents with bipolar disorder (BP) and offspring of community control parents. Methods 122 preschool offspring (mean age 3.3 years) of 84 parents with BP, with 102 offspring of 65 control parents (36 healthy, 29 with non-BP psychopathology), were evaluated using the Child Behavior Checklist (CBCL), the CBCL-Dysregulation Profile (CBCL-DP), the Early Childhood Inventory (ECI-4), and the Emotionality Activity Sociability (EAS) survey. Teachers' Report Forms (TRF) were available for 51 preschoolers. Results After adjusting for confounders, offspring of parents with BP showed higher scores in the CBCL total, externalizing, somatic, sleep, aggressive, and CBCL-DP subscales; the ECI-4 sleep problem scale; and the EAS total and emotionality scale. The proportion of offspring with CBCL T-scores ?2 SD above the norm was significantly higher on most CBCL subscales and the CBCL-DP in offspring of parents with BP compared to offspring of controls even after excluding offspring with attention deficit hyperactivity disorder and/or oppositional defiant disorder. Compared to offspring of parents with BP-I, offspring of parents with BP-II showed significantly higher scores in total and most CBCL subscales, the ECI-4 anxiety and sleep scales and the EAS emotionality scale. For both groups of parents, there were significant correlations between CBCL and TRF scores (r = .32–.38, p-values ?.02). Conclusions Independent of categorical axis-I psychopathology and other demographic or clinical factors in both biological parents, preschool offspring of parents with BP have significantly greater aggression, mood dysregulation, sleep disturbances, and somatic complaints compared to offspring of control parents. Interventions to target these symptoms are warranted. En ligne : http://dx.doi.org/10.1111/jcpp.12137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 Expressed Emotion in Mothers of Currently Depressed, Remitted, High-Risk, and Low-Risk Youth: Links to Child Depression Status and Longitudinal Course / Jennifer S. SILK in Journal of Clinical Child & Adolescent Psychology, 38-1 (January-February 2009)
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Titre : Expressed Emotion in Mothers of Currently Depressed, Remitted, High-Risk, and Low-Risk Youth: Links to Child Depression Status and Longitudinal Course Type de document : Texte imprimé et/ou numérique Auteurs : Jennifer S. SILK, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; Neal D. RYAN, Auteur ; Ronald E. DAHL, Auteur ; Douglas E. WILLIAMSON, Auteur ; Diana J. WHALEN, Auteur ; Melissa L. ZIEGLER, Auteur ; Laura J. DIETZ, Auteur Année de publication : 2009 Article en page(s) : p.36-47 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study examined expressed emotion in the families of children and adolescents who were (a) in a current episode of Major Depressive Disorder (MDD), (b) in remission from a past episode of MDD, (c) at high familial risk for developing MDD, and (d) low-risk controls. Participants were 109 mother-child dyads (children ages 8-19). Expressed emotion was assessed using the Five Minute Speech Sample, and psychiatric follow-ups were conducted annually. Mothers of children with a current or remitted episode of MDD and at high risk for MDD were more likely to be rated high on criticism than mothers of controls. There were no differences in critical expressed emotion among mothers of children in the current, remitted, or high-risk for depression groups. Higher initial critical expressed emotion was associated with a greater likelihood of having a future onset of a depressive episode in high-risk and depressed participants. Diagnostic groups did not differ in Emotional Overinvolvement. En ligne : http://dx.doi.org/10.1080/15374410802575339 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=682
in Journal of Clinical Child & Adolescent Psychology > 38-1 (January-February 2009) . - p.36-47[article] Expressed Emotion in Mothers of Currently Depressed, Remitted, High-Risk, and Low-Risk Youth: Links to Child Depression Status and Longitudinal Course [Texte imprimé et/ou numérique] / Jennifer S. SILK, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; Neal D. RYAN, Auteur ; Ronald E. DAHL, Auteur ; Douglas E. WILLIAMSON, Auteur ; Diana J. WHALEN, Auteur ; Melissa L. ZIEGLER, Auteur ; Laura J. DIETZ, Auteur . - 2009 . - p.36-47.
Langues : Anglais (eng)
in Journal of Clinical Child & Adolescent Psychology > 38-1 (January-February 2009) . - p.36-47
Index. décimale : PER Périodiques Résumé : This study examined expressed emotion in the families of children and adolescents who were (a) in a current episode of Major Depressive Disorder (MDD), (b) in remission from a past episode of MDD, (c) at high familial risk for developing MDD, and (d) low-risk controls. Participants were 109 mother-child dyads (children ages 8-19). Expressed emotion was assessed using the Five Minute Speech Sample, and psychiatric follow-ups were conducted annually. Mothers of children with a current or remitted episode of MDD and at high risk for MDD were more likely to be rated high on criticism than mothers of controls. There were no differences in critical expressed emotion among mothers of children in the current, remitted, or high-risk for depression groups. Higher initial critical expressed emotion was associated with a greater likelihood of having a future onset of a depressive episode in high-risk and depressed participants. Diagnostic groups did not differ in Emotional Overinvolvement. En ligne : http://dx.doi.org/10.1080/15374410802575339 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=682 Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization / Cecile D. LADOUCEUR in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)
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Titre : Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization Type de document : Texte imprimé et/ou numérique Auteurs : Cecile D. LADOUCEUR, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; Neal D. RYAN, Auteur ; Ronald E. DAHL, Auteur Année de publication : 2007 Article en page(s) : p.1073–1082 Langues : Anglais (eng) Mots-clés : Children anxiety-disorders error-related-negativity-(ERN) error-related-positivity-(PE) anterior-cingulate-cortex event-related-potentialssource-localization Index. décimale : PER Périodiques Résumé : Background: In this study we used event-related potentials (ERPs) and source localization analyses to track the time course of neural activity underlying response monitoring in children diagnosed with an anxiety disorder compared to age-matched low-risk normal controls.
Methods: High-density ERPs were examined following errors on a flanker task from 12 children between 8 and 14 years old diagnosed with an anxiety disorder (ANX) and 13 age-matched low-risk normal controls (LRNC).
Results: Children diagnosed with an anxiety disorder had increased error-related negativity (ERN) amplitude. The neural generators of the ERN in the ANX group were estimated to be localized in the anterior cingulate cortex (ACC). There were no significant group differences in PE amplitude.
Conclusions: These data provide evidence for increased ERN amplitude localized to the ACC in children diagnosed with an anxiety disorder, suggesting altered maturational patterns of the ACC circuitry early in the course of this illness.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01654.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=797
in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1073–1082[article] Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization [Texte imprimé et/ou numérique] / Cecile D. LADOUCEUR, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; Neal D. RYAN, Auteur ; Ronald E. DAHL, Auteur . - 2007 . - p.1073–1082.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1073–1082
Mots-clés : Children anxiety-disorders error-related-negativity-(ERN) error-related-positivity-(PE) anterior-cingulate-cortex event-related-potentialssource-localization Index. décimale : PER Périodiques Résumé : Background: In this study we used event-related potentials (ERPs) and source localization analyses to track the time course of neural activity underlying response monitoring in children diagnosed with an anxiety disorder compared to age-matched low-risk normal controls.
Methods: High-density ERPs were examined following errors on a flanker task from 12 children between 8 and 14 years old diagnosed with an anxiety disorder (ANX) and 13 age-matched low-risk normal controls (LRNC).
Results: Children diagnosed with an anxiety disorder had increased error-related negativity (ERN) amplitude. The neural generators of the ERN in the ANX group were estimated to be localized in the anterior cingulate cortex (ACC). There were no significant group differences in PE amplitude.
Conclusions: These data provide evidence for increased ERN amplitude localized to the ACC in children diagnosed with an anxiety disorder, suggesting altered maturational patterns of the ACC circuitry early in the course of this illness.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01654.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=797 Processing emotional facial expressions influences performance on a Go/NoGo task in pediatric anxiety and depression / Cecile D. LADOUCEUR in Journal of Child Psychology and Psychiatry, 47-11 (November 2006)
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PermalinkReward-related decision-making in pediatric major depressive disorder: an fMRI study / Erika E. FORBES in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)
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