How nonshared environmental factors come to correlate with heredity / Christopher R. BEAM in Development and Psychopathology, 34-1 (February 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-1 (February 2022) . - p.321-333 Titre : How nonshared environmental factors come to correlate with heredity Type de document : Texte imprimé et/ou numérique Auteurs : Christopher R. BEAM, Auteur ; Patrizia PEZZOLI, Auteur ; Jane MENDLE, Auteur ; S. Alexandra BURT, Auteur ; Michael C. NEALE, Auteur ; Steven M. BOKER, Auteur ; Pamela K. KEEL, Auteur ; Kelly L. KLUMP, Auteur Article en page(s) : p.321-333 Langues : Anglais (eng) Mots-clés : affect  developmental behavioral genetics  gene?environment interplay  longitudinal modeling  mood Index. décimale : PER Périodiques Résumé : Conventional longitudinal behavioral genetic models estimate the relative contribution of genetic and environmental factors to stability and change of traits and behaviors. Longitudinal models rarely explain the processes that generate observed differences between genetically and socially related individuals. We propose that exchanges between individuals and their environments (i.e., phenotype?environment effects) can explain the emergence of observed differences over time. Phenotype?environment models, however, would require violation of the independence assumption of standard behavioral genetic models; that is, uncorrelated genetic and environmental factors. We review how specification of phenotype?environment effects contributes to understanding observed changes in genetic variability over time and longitudinal correlations among nonshared environmental factors. We then provide an example using 30 days of positive and negative affect scores from an all-female sample of twins. Results demonstrate that the phenotype?environment effects explain how heritability estimates fluctuate as well as how nonshared environmental factors persist over time. We discuss possible mechanisms underlying change in gene?environment correlation over time, the advantages and challenges of including gene?environment correlation in longitudinal twin models, and recommendations for future research. En ligne : http://dx.doi.org/10.1017/s0954579420001017 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] How nonshared environmental factors come to correlate with heredity [Texte imprimé et/ou numérique] / Christopher R. BEAM, Auteur ; Patrizia PEZZOLI, Auteur ; Jane MENDLE, Auteur ; S. Alexandra BURT, Auteur ; Michael C. NEALE, Auteur ; Steven M. BOKER, Auteur ; Pamela K. KEEL, Auteur ; Kelly L. KLUMP, Auteur . - p.321-333. Langues : Anglais (eng) in Development and Psychopathology > 34-1 (February 2022) . - p.321-333 Mots-clés : affect  developmental behavioral genetics  gene?environment interplay  longitudinal modeling  mood Index. décimale : PER Périodiques Résumé : Conventional longitudinal behavioral genetic models estimate the relative contribution of genetic and environmental factors to stability and change of traits and behaviors. Longitudinal models rarely explain the processes that generate observed differences between genetically and socially related individuals. We propose that exchanges between individuals and their environments (i.e., phenotype?environment effects) can explain the emergence of observed differences over time. Phenotype?environment models, however, would require violation of the independence assumption of standard behavioral genetic models; that is, uncorrelated genetic and environmental factors. We review how specification of phenotype?environment effects contributes to understanding observed changes in genetic variability over time and longitudinal correlations among nonshared environmental factors. We then provide an example using 30 days of positive and negative affect scores from an all-female sample of twins. Results demonstrate that the phenotype?environment effects explain how heritability estimates fluctuate as well as how nonshared environmental factors persist over time. We discuss possible mechanisms underlying change in gene?environment correlation over time, the advantages and challenges of including gene?environment correlation in longitudinal twin models, and recommendations for future research. En ligne : http://dx.doi.org/10.1017/s0954579420001017 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Maternal warmth and directiveness jointly moderate the etiology of childhood conduct problems / S. Alexandra BURT in Journal of Child Psychology and Psychiatry, 54-10 (October 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-10 (October 2013) . - p.1030-1037 Titre : Maternal warmth and directiveness jointly moderate the etiology of childhood conduct problems Type de document : Texte imprimé et/ou numérique Auteurs : S. Alexandra BURT, Auteur ; Ashlea M. KLAHR, Auteur ; Michael C. NEALE, Auteur ; Kelly L. KLUMP, Auteur Article en page(s) : p.1030-1037 Langues : Anglais (eng) Mots-clés : Child conduct problems  GxE  maternal directiveness or control  maternal warmth Index. décimale : PER Périodiques Résumé : Background Prior studies exploring gene–environment interactions (GxE) in the development of youth conduct problems (CP) have focused almost exclusively on single-risk experiences, despite research indicating that the presence of other risk factors and or the absence of protective factors can accentuate the influence of a given risk factor on CP. The goal of the current study was to fill this gap in the literature, evaluating whether risky and protective aspects of parenting might combine to jointly moderate the etiology of CP. Methods The sample consisted of 500 child twin pairs from the Michigan State University Twin Registry (MSUTR). Child CP was assessed using multiple informant reports. Maternal warmth and directiveness were assessed via videotaped dyadic interactions between mothers and each of their twins. Results Biometric GxE analyses revealed that directiveness and warmth did appear to jointly moderate the etiology of CP. In particular, shared environmental influences were accentuated by colder, less directive or ‘less engaged’ mothering, whereas genetic influences were strongest when the child was experiencing warmer, more directive or ‘more authoritative’ mothering. Conclusions Such findings serve to highlight the synergistic effects of risky and protective experiences on child outcomes. They also provide additional empirical support for the bioecological form of GxE, which postulates that, in some cases, genetic influences may be most strongly expressed in the presence of low-risk environments. En ligne : http://dx.doi.org/10.1111/jcpp.12095 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Maternal warmth and directiveness jointly moderate the etiology of childhood conduct problems [Texte imprimé et/ou numérique] / S. Alexandra BURT, Auteur ; Ashlea M. KLAHR, Auteur ; Michael C. NEALE, Auteur ; Kelly L. KLUMP, Auteur . - p.1030-1037. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-10 (October 2013) . - p.1030-1037 Mots-clés : Child conduct problems  GxE  maternal directiveness or control  maternal warmth Index. décimale : PER Périodiques Résumé : Background Prior studies exploring gene–environment interactions (GxE) in the development of youth conduct problems (CP) have focused almost exclusively on single-risk experiences, despite research indicating that the presence of other risk factors and or the absence of protective factors can accentuate the influence of a given risk factor on CP. The goal of the current study was to fill this gap in the literature, evaluating whether risky and protective aspects of parenting might combine to jointly moderate the etiology of CP. Methods The sample consisted of 500 child twin pairs from the Michigan State University Twin Registry (MSUTR). Child CP was assessed using multiple informant reports. Maternal warmth and directiveness were assessed via videotaped dyadic interactions between mothers and each of their twins. Results Biometric GxE analyses revealed that directiveness and warmth did appear to jointly moderate the etiology of CP. In particular, shared environmental influences were accentuated by colder, less directive or ‘less engaged’ mothering, whereas genetic influences were strongest when the child was experiencing warmer, more directive or ‘more authoritative’ mothering. Conclusions Such findings serve to highlight the synergistic effects of risky and protective experiences on child outcomes. They also provide additional empirical support for the bioecological form of GxE, which postulates that, in some cases, genetic influences may be most strongly expressed in the presence of low-risk environments. En ligne : http://dx.doi.org/10.1111/jcpp.12095 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

A pediatric twin study of brain morphometry / Gregory L. WALLACE in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.987–993 Titre : A pediatric twin study of brain morphometry Type de document : Texte imprimé et/ou numérique Auteurs : Gregory L. WALLACE, Auteur ; Michael A. ROSENTHAL, Auteur ; Michael C. NEALE, Auteur ; Kenneth S. KENDLER, Auteur ; Liv S. CLASEN, Auteur ; Elizabeth A. MOLLOY, Auteur ; Sarah ORDAZ, Auteur ; Essi VIDING, Auteur ; Rhoshel LENROOT, Auteur ; J. Eric SCHMITT, Auteur ; Jay N. GIEDD, Auteur Année de publication : 2007 Article en page(s) : p.987–993 Langues : Anglais (eng) Mots-clés : Brain-development brain-imaging pediatric twin behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajectories. Method: Magnetic resonance imaging brain scans were acquired on a pediatric sample of 90 monozygotic twin pairs, 38 same-sex dyzygotic twin pairs, and 158 unrelated typically developing singletons. Structural equation modeling was used to estimate the additive genetic, common environment, and unique environment effects, as well as age by heritability interactions, on measures of brain volumes from these images. Results: Consistent with previous adult studies, additive genetic effects accounted for a substantial portion of variability in nearly all brain regions with the notable exception of the cerebellum. Significant age by heritability interactions were observed with gray matter volumes showing a reduction in heritability with increasing age, while white matter volume heritability increased with greater age. Conclusion: Understanding the relative contributions of genetic and nongenetic factors on developmental brain trajectories may have implications for better understanding brain-based disorders and typical cognitive development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01676.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788 [article] A pediatric twin study of brain morphometry [Texte imprimé et/ou numérique] / Gregory L. WALLACE, Auteur ; Michael A. ROSENTHAL, Auteur ; Michael C. NEALE, Auteur ; Kenneth S. KENDLER, Auteur ; Liv S. CLASEN, Auteur ; Elizabeth A. MOLLOY, Auteur ; Sarah ORDAZ, Auteur ; Essi VIDING, Auteur ; Rhoshel LENROOT, Auteur ; J. Eric SCHMITT, Auteur ; Jay N. GIEDD, Auteur . - 2007 . - p.987–993. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.987–993 Mots-clés : Brain-development brain-imaging pediatric twin behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajectories. Method: Magnetic resonance imaging brain scans were acquired on a pediatric sample of 90 monozygotic twin pairs, 38 same-sex dyzygotic twin pairs, and 158 unrelated typically developing singletons. Structural equation modeling was used to estimate the additive genetic, common environment, and unique environment effects, as well as age by heritability interactions, on measures of brain volumes from these images. Results: Consistent with previous adult studies, additive genetic effects accounted for a substantial portion of variability in nearly all brain regions with the notable exception of the cerebellum. Significant age by heritability interactions were observed with gray matter volumes showing a reduction in heritability with increasing age, while white matter volume heritability increased with greater age. Conclusion: Understanding the relative contributions of genetic and nongenetic factors on developmental brain trajectories may have implications for better understanding brain-based disorders and typical cognitive development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01676.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788

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