Interactions among catechol-O-methyltransferase genotype, parenting, and sex predict children's internalizing symptoms and inhibitory control: Evidence for differential susceptibility / Michael J. SULIK in Development and Psychopathology, 27-3 (August 2015)  

Public ISBD [article]  inDevelopment and Psychopathology > 27-3 (August 2015) . - p.709-723 Titre : Interactions among catechol-O-methyltransferase genotype, parenting, and sex predict children's internalizing symptoms and inhibitory control: Evidence for differential susceptibility Type de document : Texte imprimé et/ou numérique Auteurs : Michael J. SULIK, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur ; Kathryn LEMERY-CHALFANT, Auteur ; Gregory SWANN, Auteur ; Kassondra M. SILVA, Auteur ; Mark REISER, Auteur ; Daryn A. STOVER, Auteur ; Brian C. VERRELLI, Auteur Article en page(s) : p.709-723 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We used sex, observed parenting quality at 18 months, and three variants of the catechol-O-methyltransferase gene (Val158Met [rs4680], intron1 [rs737865], and 3?-untranslated region [rs165599]) to predict mothers' reports of inhibitory and attentional control (assessed at 42, 54, 72, and 84 months) and internalizing symptoms (assessed at 24, 30, 42, 48, and 54 months) in a sample of 146 children (79 male). Although the pattern for all three variants was very similar, Val158Met explained more variance in both outcomes than did intron1, the 3?-untranslated region, or a haplotype that combined all three catechol-O-methyltransferase variants. In separate models, there were significant three-way interactions among each of the variants, parenting, and sex, predicting the intercepts of inhibitory control and internalizing symptoms. Results suggested that Val158Met indexes plasticity, although this effect was moderated by sex. Parenting was positively associated with inhibitory control for methionine–methionine boys and for valine–valine/valine–methionine girls, and was negatively associated with internalizing symptoms for methionine–methionine boys. Using the “regions of significance” technique, genetic differences in inhibitory control were found for children exposed to high-quality parenting, whereas genetic differences in internalizing were found for children exposed to low-quality parenting. These findings provide evidence in support of testing for differential susceptibility across multiple outcomes. En ligne : http://dx.doi.org/10.1017/S0954579414000807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 [article] Interactions among catechol-O-methyltransferase genotype, parenting, and sex predict children's internalizing symptoms and inhibitory control: Evidence for differential susceptibility [Texte imprimé et/ou numérique] / Michael J. SULIK, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur ; Kathryn LEMERY-CHALFANT, Auteur ; Gregory SWANN, Auteur ; Kassondra M. SILVA, Auteur ; Mark REISER, Auteur ; Daryn A. STOVER, Auteur ; Brian C. VERRELLI, Auteur . - p.709-723. Langues : Anglais (eng) in Development and Psychopathology > 27-3 (August 2015) . - p.709-723 Index. décimale : PER Périodiques Résumé : We used sex, observed parenting quality at 18 months, and three variants of the catechol-O-methyltransferase gene (Val158Met [rs4680], intron1 [rs737865], and 3?-untranslated region [rs165599]) to predict mothers' reports of inhibitory and attentional control (assessed at 42, 54, 72, and 84 months) and internalizing symptoms (assessed at 24, 30, 42, 48, and 54 months) in a sample of 146 children (79 male). Although the pattern for all three variants was very similar, Val158Met explained more variance in both outcomes than did intron1, the 3?-untranslated region, or a haplotype that combined all three catechol-O-methyltransferase variants. In separate models, there were significant three-way interactions among each of the variants, parenting, and sex, predicting the intercepts of inhibitory control and internalizing symptoms. Results suggested that Val158Met indexes plasticity, although this effect was moderated by sex. Parenting was positively associated with inhibitory control for methionine–methionine boys and for valine–valine/valine–methionine girls, and was negatively associated with internalizing symptoms for methionine–methionine boys. Using the “regions of significance” technique, genetic differences in inhibitory control were found for children exposed to high-quality parenting, whereas genetic differences in internalizing were found for children exposed to low-quality parenting. These findings provide evidence in support of testing for differential susceptibility across multiple outcomes. En ligne : http://dx.doi.org/10.1017/S0954579414000807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

Relations among maternal socialization, effortful control, and maladjustment in early childhood / Nancy EISENBERG in Development and Psychopathology, 22-3 (August 2010)  

Public ISBD [article]  inDevelopment and Psychopathology > 22-3 (August 2010) . - p.507-525 Titre : Relations among maternal socialization, effortful control, and maladjustment in early childhood Type de document : Texte imprimé et/ou numérique Auteurs : Nancy EISENBERG, Auteur ; Tierney POPP, Auteur ; Bridget M. GAERTNER, Auteur ; Cynthia L. SMITH, Auteur ; Claire HOFER, Auteur ; Kassondra M. SILVA, Auteur ; Mark REISER, Auteur ; Anne S. KUPFER, Auteur ; Tracy L. SPINRAD, Auteur ; Natalie D. EGGUM, Auteur ; Nicole MICHALIK, Auteur Année de publication : 2010 Article en page(s) : p.507-525 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : In a sample of 18-, 30-, and 42-month-olds, the relations among parenting, effortful control (EC), and maladjustment were examined. Parenting was assessed with mothers' reports and observations; EC was measured with mothers' and caregivers' reports, as well as a behavioral task; and externalizing and internalizing symptoms were assessed with parents' and caregivers' reports. Although 18-month unsupportive (vs. supportive) parenting negatively predicted EC at 30 months, when the stability of these variables was taken into account, there was no evidence of additional potentially causal relations between these two constructs. Although EC was negatively related to both internalizing and externalizing problems within all three ages as well as across 1 year, EC did not predict maladjustment once the stability of the constructs and within time covariation between the constructs were taken into account. In addition, externalizing problems at 30 months negatively predicted EC at 42 months, and internalizing problems at 30 months positively predicted EC at 42 months, but only when the effects of externalizing on EC were controlled. The findings are discussed in terms of the reasons for the lack of causal relations over time. En ligne : http://dx.doi.org/10.1017/s0954579410000246 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108 [article] Relations among maternal socialization, effortful control, and maladjustment in early childhood [Texte imprimé et/ou numérique] / Nancy EISENBERG, Auteur ; Tierney POPP, Auteur ; Bridget M. GAERTNER, Auteur ; Cynthia L. SMITH, Auteur ; Claire HOFER, Auteur ; Kassondra M. SILVA, Auteur ; Mark REISER, Auteur ; Anne S. KUPFER, Auteur ; Tracy L. SPINRAD, Auteur ; Natalie D. EGGUM, Auteur ; Nicole MICHALIK, Auteur . - 2010 . - p.507-525. Langues : Anglais (eng) in Development and Psychopathology > 22-3 (August 2010) . - p.507-525 Index. décimale : PER Périodiques Résumé : In a sample of 18-, 30-, and 42-month-olds, the relations among parenting, effortful control (EC), and maladjustment were examined. Parenting was assessed with mothers' reports and observations; EC was measured with mothers' and caregivers' reports, as well as a behavioral task; and externalizing and internalizing symptoms were assessed with parents' and caregivers' reports. Although 18-month unsupportive (vs. supportive) parenting negatively predicted EC at 30 months, when the stability of these variables was taken into account, there was no evidence of additional potentially causal relations between these two constructs. Although EC was negatively related to both internalizing and externalizing problems within all three ages as well as across 1 year, EC did not predict maladjustment once the stability of the constructs and within time covariation between the constructs were taken into account. In addition, externalizing problems at 30 months negatively predicted EC at 42 months, and internalizing problems at 30 months positively predicted EC at 42 months, but only when the effects of externalizing on EC were controlled. The findings are discussed in terms of the reasons for the lack of causal relations over time. En ligne : http://dx.doi.org/10.1017/s0954579410000246 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108

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