Autism and lack of D3 vitamin: A systematic review / Giovanni PIOGGIA in Research in Autism Spectrum Disorders, 8-12 (December 2014)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 8-12 (December 2014) . - p.1685-1698 Titre : Autism and lack of D3 vitamin: A systematic review Type de document : texte imprimé Auteurs : Giovanni PIOGGIA, Auteur ; A. TONACCI, Auteur ; G. TARTARISCO, Auteur ; Lucia BILLECI, Auteur ; Filippo MURATORI, Auteur ; Liliana RUTA, Auteur ; S. GANGEMI, Auteur Article en page(s) : p.1685-1698 Langues : Anglais (eng) Mots-clés : Autism  Autoimmune disease  Brain function  Cholecalciferol  Neurodevelopmental disorders  Vitamin D3 Index. décimale : PER Périodiques Résumé : Abstract Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by social communication deficits and restricted, repetitive patterns of behavior. Several medical conditions including gastrointestinal (GI) problems, asthma and allergies have been associated with ASD, and multiple risk factors, both genetic and environmental, have been proposed. Among them, vitamin D (VD) deficiency is probably associated with ASD, and may play a role in the condition. We conducted a systematic review of the literature for the period January 1, 2010 through June 15, 2014, according to PRISMA guidelines, aiming to investigate the complex biological interplay between VD, metabolism, immune system and nervous system in ASD. Different trends in the association between ASD and VD deficiency have been observed, and factors such as gender, ethnicity, sampling, and methodology play a role in the results and outcomes. At present, for at least a subgroup of ASD individuals, an imbalance in VD metabolism probably exists and may be associated with the condition. In this cohort, VD replacement in these individuals might contribute to improving ASD symptoms and/or associated conditions. This topic is an important challenge for future research, and could lead to a new tailored therapeutic approach for VD in ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.09.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 [article] Autism and lack of D3 vitamin: A systematic review [texte imprimé] / Giovanni PIOGGIA, Auteur ; A. TONACCI, Auteur ; G. TARTARISCO, Auteur ; Lucia BILLECI, Auteur ; Filippo MURATORI, Auteur ; Liliana RUTA, Auteur ; S. GANGEMI, Auteur . - p.1685-1698. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 8-12 (December 2014) . - p.1685-1698 Mots-clés : Autism  Autoimmune disease  Brain function  Cholecalciferol  Neurodevelopmental disorders  Vitamin D3 Index. décimale : PER Périodiques Résumé : Abstract Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by social communication deficits and restricted, repetitive patterns of behavior. Several medical conditions including gastrointestinal (GI) problems, asthma and allergies have been associated with ASD, and multiple risk factors, both genetic and environmental, have been proposed. Among them, vitamin D (VD) deficiency is probably associated with ASD, and may play a role in the condition. We conducted a systematic review of the literature for the period January 1, 2010 through June 15, 2014, according to PRISMA guidelines, aiming to investigate the complex biological interplay between VD, metabolism, immune system and nervous system in ASD. Different trends in the association between ASD and VD deficiency have been observed, and factors such as gender, ethnicity, sampling, and methodology play a role in the results and outcomes. At present, for at least a subgroup of ASD individuals, an imbalance in VD metabolism probably exists and may be associated with the condition. In this cohort, VD replacement in these individuals might contribute to improving ASD symptoms and/or associated conditions. This topic is an important challenge for future research, and could lead to a new tailored therapeutic approach for VD in ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.09.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243

Autism and social robotics: A systematic review / Paola PENNISI in Autism Research, 9-2 (February 2016)  

Public ISBD [article]  inAutism Research > 9-2 (February 2016) . - p.165-183 Titre : Autism and social robotics: A systematic review Type de document : texte imprimé Auteurs : Paola PENNISI, Auteur ; Alessandro TONACCI, Auteur ; Gennaro TARTARISCO, Auteur ; Lucia BILLECI, Auteur ; Liliana RUTA, Auteur ; Sebastiano GANGEMI, Auteur ; Giovanni PIOGGIA, Auteur Article en page(s) : p.165-183 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  social robotics  autism therapy  humanoid robots  autism diagnosis Index. décimale : PER Périodiques Résumé : Social robotics could be a promising method for Autism Spectrum Disorders (ASD) treatment. The aim of this article is to carry out a systematic literature review of the studies on this topic that were published in the last 10 years. We tried to address the following questions: can social robots be a useful tool in autism therapy? We followed the PRISMA guidelines, and the protocol was registered within PROSPERO database (CRD42015016158). We found many positive implications in the use of social robots in therapy as for example: ASD subjects often performed better with a robot partner rather than a human partner; sometimes, ASD patients had, toward robots, behaviors that TD patients had toward human agents; ASDs had a lot of social behaviors toward robots; during robotic sessions, ASDs showed reduced repetitive and stereotyped behaviors and, social robots manage to improve spontaneous language during therapy sessions. Therefore, robots provide therapists and researchers a means to connect with autistic subjects in an easier way, but studies in this area are still insufficient. It is necessary to clarify whether sex, intelligence quotient, and age of participants affect the outcome of therapy and whether any beneficial effects only occur during the robotic session or if they are still observable outside the clinical/experimental context. En ligne : http://dx.doi.org/10.1002/aur.1527 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282 [article] Autism and social robotics: A systematic review [texte imprimé] / Paola PENNISI, Auteur ; Alessandro TONACCI, Auteur ; Gennaro TARTARISCO, Auteur ; Lucia BILLECI, Auteur ; Liliana RUTA, Auteur ; Sebastiano GANGEMI, Auteur ; Giovanni PIOGGIA, Auteur . - p.165-183. Langues : Anglais (eng) in Autism Research > 9-2 (February 2016) . - p.165-183 Mots-clés : autism spectrum disorder  social robotics  autism therapy  humanoid robots  autism diagnosis Index. décimale : PER Périodiques Résumé : Social robotics could be a promising method for Autism Spectrum Disorders (ASD) treatment. The aim of this article is to carry out a systematic literature review of the studies on this topic that were published in the last 10 years. We tried to address the following questions: can social robots be a useful tool in autism therapy? We followed the PRISMA guidelines, and the protocol was registered within PROSPERO database (CRD42015016158). We found many positive implications in the use of social robots in therapy as for example: ASD subjects often performed better with a robot partner rather than a human partner; sometimes, ASD patients had, toward robots, behaviors that TD patients had toward human agents; ASDs had a lot of social behaviors toward robots; during robotic sessions, ASDs showed reduced repetitive and stereotyped behaviors and, social robots manage to improve spontaneous language during therapy sessions. Therefore, robots provide therapists and researchers a means to connect with autistic subjects in an easier way, but studies in this area are still insufficient. It is necessary to clarify whether sex, intelligence quotient, and age of participants affect the outcome of therapy and whether any beneficial effects only occur during the robotic session or if they are still observable outside the clinical/experimental context. En ligne : http://dx.doi.org/10.1002/aur.1527 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282

Brief Report: Neuroimaging Endophenotypes of Social Robotic Applications in Autism Spectrum Disorder / Antonio CERASA in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2538-2542 Titre : Brief Report: Neuroimaging Endophenotypes of Social Robotic Applications in Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Antonio CERASA, Auteur ; Liliana RUTA, Auteur ; Flavia MARINO, Auteur ; Giuseppe BIAMONTI, Auteur ; Giovanni PIOGGIA, Auteur Article en page(s) : p.2538-2542 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/genetics/therapy  Autistic Disorder  Child  Creativity  Endophenotypes  Humans  Male  Neuroimaging  Research Report  Robotics/methods  Autism spectrum disorder  Neuroendophenotype  Social robot Index. décimale : PER Périodiques Résumé : A plethora of neuroimaging studies have focused on the discovery of potential neuroendophenotypes useful to understand the etiopathogenesis of autism and predict treatment response. Social robotics has recently been proposed as an effective tool to strengthen the current treatments in children with autism. However, the high clinical heterogeneity characterizing this disorder might interfere with behavioral effects. Neuroimaging is set to overcome these limitations by capturing the level of heterogeneity. Here, we provide a preliminary evaluation of the neural basis of social robotics and how extracting neural hallmarks useful to design more effective behavioral applications. Despite the endophenotype-oriented neuroimaging research approach is in its relative infancy, this preliminary evidence encourages innovation to address its current limitations. En ligne : http://dx.doi.org/10.1007/s10803-020-04708-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Brief Report: Neuroimaging Endophenotypes of Social Robotic Applications in Autism Spectrum Disorder [texte imprimé] / Antonio CERASA, Auteur ; Liliana RUTA, Auteur ; Flavia MARINO, Auteur ; Giuseppe BIAMONTI, Auteur ; Giovanni PIOGGIA, Auteur . - p.2538-2542. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2538-2542 Mots-clés : Autism Spectrum Disorder/genetics/therapy  Autistic Disorder  Child  Creativity  Endophenotypes  Humans  Male  Neuroimaging  Research Report  Robotics/methods  Autism spectrum disorder  Neuroendophenotype  Social robot Index. décimale : PER Périodiques Résumé : A plethora of neuroimaging studies have focused on the discovery of potential neuroendophenotypes useful to understand the etiopathogenesis of autism and predict treatment response. Social robotics has recently been proposed as an effective tool to strengthen the current treatments in children with autism. However, the high clinical heterogeneity characterizing this disorder might interfere with behavioral effects. Neuroimaging is set to overcome these limitations by capturing the level of heterogeneity. Here, we provide a preliminary evaluation of the neural basis of social robotics and how extracting neural hallmarks useful to design more effective behavioral applications. Despite the endophenotype-oriented neuroimaging research approach is in its relative infancy, this preliminary evidence encourages innovation to address its current limitations. En ligne : http://dx.doi.org/10.1007/s10803-020-04708-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Brief Report: Peculiar Evolution of Autistic Behaviors in Two Unrelated Children with Brachidactyly-Mental Retardation Syndrome / Luigi MAZZONE in Journal of Autism and Developmental Disorders, 42-10 (October 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-10 (October 2012) . - p.2202-2207 Titre : Brief Report: Peculiar Evolution of Autistic Behaviors in Two Unrelated Children with Brachidactyly-Mental Retardation Syndrome Type de document : texte imprimé Auteurs : Luigi MAZZONE, Auteur ; Lia VASSENA, Auteur ; Liliana RUTA, Auteur ; Diego MUGNO, Auteur ; Ornella GALESI, Auteur ; Marco FICHERA, Auteur Année de publication : 2012 Article en page(s) : p.2202-2207 Langues : Anglais (eng) Mots-clés : Autism  2q37 region  BDMR  Evolutionary course Index. décimale : PER Périodiques Résumé : Brachidactyly-Mental Retardation (BDMR) Syndrome (MIM 600430) is associated with terminal deletions at chromosome 2q37 and a limited number of studies also reported an association between 2q37 → qter deletion and autism. Herein we describe two cases of autism in unrelated children with BDMR Syndrome, showing physical, cognitive, behavioral, and disease natural history homologies, with a very prominent social impairment in the first 4 years of life. At follow-up evaluations, spanning a 5-years period, both children experienced a progressive reduction of the autistic symptoms, besides retaining compromised cognitive ability. This report supports the hypothesis that genes in the 2q37 region may contribute to the etiology of autism, leading, however, to a peculiar evolution of the disease, with symptoms severity decreasing over time. En ligne : http://dx.doi.org/10.1007/s10803-011-1432-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Brief Report: Peculiar Evolution of Autistic Behaviors in Two Unrelated Children with Brachidactyly-Mental Retardation Syndrome [texte imprimé] / Luigi MAZZONE, Auteur ; Lia VASSENA, Auteur ; Liliana RUTA, Auteur ; Diego MUGNO, Auteur ; Ornella GALESI, Auteur ; Marco FICHERA, Auteur . - 2012 . - p.2202-2207. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-10 (October 2012) . - p.2202-2207 Mots-clés : Autism  2q37 region  BDMR  Evolutionary course Index. décimale : PER Périodiques Résumé : Brachidactyly-Mental Retardation (BDMR) Syndrome (MIM 600430) is associated with terminal deletions at chromosome 2q37 and a limited number of studies also reported an association between 2q37 → qter deletion and autism. Herein we describe two cases of autism in unrelated children with BDMR Syndrome, showing physical, cognitive, behavioral, and disease natural history homologies, with a very prominent social impairment in the first 4 years of life. At follow-up evaluations, spanning a 5-years period, both children experienced a progressive reduction of the autistic symptoms, besides retaining compromised cognitive ability. This report supports the hypothesis that genes in the 2q37 region may contribute to the etiology of autism, leading, however, to a peculiar evolution of the disease, with symptoms severity decreasing over time. En ligne : http://dx.doi.org/10.1007/s10803-011-1432-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

Implementation of the Early Start Denver Model in an Italian community / Costanza COLOMBI in Autism, 22-2 (February 2018)  

Public ISBD [article]  inAutism > 22-2 (February 2018) . - p.126-133 Titre : Implementation of the Early Start Denver Model in an Italian community Type de document : texte imprimé Auteurs : Costanza COLOMBI, Auteur ; Antonio NARZISI, Auteur ; Liliana RUTA, Auteur ; Virginia CIGALA, Auteur ; Antonella GAGLIANO, Auteur ; Giovanni PIOGGIA, Auteur ; Rosamaria SIRACUSANO, Auteur ; Sally J. ROGERS, Auteur ; Filippo MURATORI, Auteur ; PRIMA PIETRA TEAM, Auteur Année de publication : 2018 Article en page(s) : p.126-133 Langues : Anglais (eng) Mots-clés : autism,autism spectrum disorder,early intervention,Early Start Denver Model,preschoolers Index. décimale : PER Périodiques Résumé : Identifying effective, community-based specialized interventions for young children with autism spectrum disorder is an international clinical and research priority. We evaluated the effectiveness of the Early Start Denver Model intervention in a group of young children with autism spectrum disorder living in an Italian community compared to a group of Italian children who received treatment as usual. A total of 22 young children diagnosed with autism spectrum disorder received the Early Start Denver Model in a center-based context for 6 h per week over 6 months. The Early Start Denver Model group was compared to a group of 70 young children diagnosed with autism spectrum disorder who received treatment as usual for an average of 5.2 h over 6 months. Children in both groups improved in cognitive, adaptive, and social skills after 3 months and 6 months of treatment. Children in the Early Start Denver Model group made larger gains in cognitive and social skills after 3 and 6 months of treatment. The Early Start Denver Model group made larger gains in adaptive skills after 3 months of treatment. Our results are discussed in terms of implications for intervention research and clinical practice. Our study supports the positive impact of the Early Start Denver Model in a non-English-speaking community. En ligne : https://doi.org/10.1177/1362361316665792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=335 [article] Implementation of the Early Start Denver Model in an Italian community [texte imprimé] / Costanza COLOMBI, Auteur ; Antonio NARZISI, Auteur ; Liliana RUTA, Auteur ; Virginia CIGALA, Auteur ; Antonella GAGLIANO, Auteur ; Giovanni PIOGGIA, Auteur ; Rosamaria SIRACUSANO, Auteur ; Sally J. ROGERS, Auteur ; Filippo MURATORI, Auteur ; PRIMA PIETRA TEAM, Auteur . - 2018 . - p.126-133. Langues : Anglais (eng) in Autism > 22-2 (February 2018) . - p.126-133 Mots-clés : autism,autism spectrum disorder,early intervention,Early Start Denver Model,preschoolers Index. décimale : PER Périodiques Résumé : Identifying effective, community-based specialized interventions for young children with autism spectrum disorder is an international clinical and research priority. We evaluated the effectiveness of the Early Start Denver Model intervention in a group of young children with autism spectrum disorder living in an Italian community compared to a group of Italian children who received treatment as usual. A total of 22 young children diagnosed with autism spectrum disorder received the Early Start Denver Model in a center-based context for 6 h per week over 6 months. The Early Start Denver Model group was compared to a group of 70 young children diagnosed with autism spectrum disorder who received treatment as usual for an average of 5.2 h over 6 months. Children in both groups improved in cognitive, adaptive, and social skills after 3 months and 6 months of treatment. Children in the Early Start Denver Model group made larger gains in cognitive and social skills after 3 and 6 months of treatment. The Early Start Denver Model group made larger gains in adaptive skills after 3 months of treatment. Our results are discussed in terms of implications for intervention research and clinical practice. Our study supports the positive impact of the Early Start Denver Model in a non-English-speaking community. En ligne : https://doi.org/10.1177/1362361316665792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=335

Outcomes of a Robot-Assisted Social-Emotional Understanding Intervention for Young Children with Autism Spectrum Disorders / Flavia MARINO in Journal of Autism and Developmental Disorders, 50-6 (June 2020)  

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Psychometric properties, factor structure and cross-cultural validity of the quantitative CHecklist for autism in toddlers (Q-CHAT) in an Italian community setting / Liliana RUTA in Research in Autism Spectrum Disorders, 64 (August 2019)  

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Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome / Hannah STEEB in Molecular Autism, (January 2014)  

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The Autism-Spectrum Quotient—Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype / Liliana RUTA in Journal of Autism and Developmental Disorders, 42-4 (April 2012)  

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The Male Prevalence in Autism Spectrum Disorders : Hypotheses on its Neurobiological Basis / Flavio KELLER

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