Dépouillements

Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders / Hirokazu KUMAZAKI in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 13-14 (May 2015) . - p.1-7 Titre : Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Hirotaka KOSAKA, Auteur ; Takashi X. FUJISAWA, Auteur ; Kazuhiko IWATA, Auteur ; Akemi TOMODA, Auteur ; Kenji TSUCHIYA, Auteur ; Masaru MIMURA, Auteur Article en page(s) : p.1-7 Langues : Anglais (eng) Mots-clés : High functioning autism spectrum disorders  Sex differences  Narrow age range  Before adolescence  CARS-TV  Taste, Smell, Touch Response and Use Index. décimale : PER Périodiques Résumé : Abstract Although a small number of studies have investigated sex differences in the associated features of high-functioning autism spectrum disorders (HFASDs), they have failed to provide consistent findings. We sought to examine sex differences in 5–9-year-old females and males with HFASDs within a narrow range of ages before adolescence in order to identify the noticeable autistic profile of females compared to males. Using the Japanese version of the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) and the Childhood Autism Rating Scale-Tokyo Version (CARS-TV), 20 females with HFASDs were compared with 26 males with HFASDs. Although females and males with HFASDs share similar cognitive profiles in WISC-III, females demonstrated a different symptom profile from males in CARS-TV. Although the female subjects scored significantly lower than the male subjects on “Body Use,” “Object Use,” and “Activity Level,” female subjects scored significantly higher than males on “Taste, Smell, and Touch Response and Use” in the CARS-TV. This finding can be useful for the early identification of females with HFASDs who have typically been underdiagnosed. Future research should focus on elucidating the possible behavioral, neurological, and genetic links to these sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders [Texte imprimé et/ou numérique] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Hirotaka KOSAKA, Auteur ; Takashi X. FUJISAWA, Auteur ; Kazuhiko IWATA, Auteur ; Akemi TOMODA, Auteur ; Kenji TSUCHIYA, Auteur ; Masaru MIMURA, Auteur . - p.1-7. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 13-14 (May 2015) . - p.1-7 Mots-clés : High functioning autism spectrum disorders  Sex differences  Narrow age range  Before adolescence  CARS-TV  Taste, Smell, Touch Response and Use Index. décimale : PER Périodiques Résumé : Abstract Although a small number of studies have investigated sex differences in the associated features of high-functioning autism spectrum disorders (HFASDs), they have failed to provide consistent findings. We sought to examine sex differences in 5–9-year-old females and males with HFASDs within a narrow range of ages before adolescence in order to identify the noticeable autistic profile of females compared to males. Using the Japanese version of the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) and the Childhood Autism Rating Scale-Tokyo Version (CARS-TV), 20 females with HFASDs were compared with 26 males with HFASDs. Although females and males with HFASDs share similar cognitive profiles in WISC-III, females demonstrated a different symptom profile from males in CARS-TV. Although the female subjects scored significantly lower than the male subjects on “Body Use,” “Object Use,” and “Activity Level,” female subjects scored significantly higher than males on “Taste, Smell, and Touch Response and Use” in the CARS-TV. This finding can be useful for the early identification of females with HFASDs who have typically been underdiagnosed. Future research should focus on elucidating the possible behavioral, neurological, and genetic links to these sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Is there a bit of autism in all of us? Autism spectrum traits are related to cortical thickness differences in both autism and typical development / Line GEBAUER in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 13-14 (May 2015) . - p.8-14 Titre : Is there a bit of autism in all of us? Autism spectrum traits are related to cortical thickness differences in both autism and typical development Type de document : Texte imprimé et/ou numérique Auteurs : Line GEBAUER, Auteur ; Nicholas E. V. FOSTER, Auteur ; Peter VUUST, Auteur ; Krista L. HYDE, Auteur Article en page(s) : p.8-14 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum quotient  Brain structure  MRI  Cortical thickness Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in communication and social interaction, as well as repetitive behaviors and interests. However, these traits are highly variable across individuals with ASD and are also present in the typically developing population. Brain structural correlates of ASD are also heterogeneous. Recent findings have indicated that ASD traits as measured by the autism quotient (AQ) are reflected in white matter structural differences in a continuous way across both typically-developed and ASD individuals. Here, we tested for the first time, how ASD traits are related to gray matter structural differences (and particularly cortical thickness) in both ASD and typically developing adults. The present results show that ASD traits are primarily correlated with reductions in cortical thickness in a continuous fashion across ASD and typically developing adults in social brain areas and the default mode network including the orbitofrontal cortex, postcentral gyrus, and lingual gyrus. These findings provide new evidence that ASD traits are primarily reflected in neural structure that exists along a continuum extending into the typically developing population. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Is there a bit of autism in all of us? Autism spectrum traits are related to cortical thickness differences in both autism and typical development [Texte imprimé et/ou numérique] / Line GEBAUER, Auteur ; Nicholas E. V. FOSTER, Auteur ; Peter VUUST, Auteur ; Krista L. HYDE, Auteur . - p.8-14. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 13-14 (May 2015) . - p.8-14 Mots-clés : Autism  Autism spectrum quotient  Brain structure  MRI  Cortical thickness Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in communication and social interaction, as well as repetitive behaviors and interests. However, these traits are highly variable across individuals with ASD and are also present in the typically developing population. Brain structural correlates of ASD are also heterogeneous. Recent findings have indicated that ASD traits as measured by the autism quotient (AQ) are reflected in white matter structural differences in a continuous way across both typically-developed and ASD individuals. Here, we tested for the first time, how ASD traits are related to gray matter structural differences (and particularly cortical thickness) in both ASD and typically developing adults. The present results show that ASD traits are primarily correlated with reductions in cortical thickness in a continuous fashion across ASD and typically developing adults in social brain areas and the default mode network including the orbitofrontal cortex, postcentral gyrus, and lingual gyrus. These findings provide new evidence that ASD traits are primarily reflected in neural structure that exists along a continuum extending into the typically developing population. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Predicting the rate of language development from early motor skills in at-risk infants who develop autism spectrum disorder / Hayley C. LEONARD in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 13-14 (May 2015) . - p.15-24 Titre : Predicting the rate of language development from early motor skills in at-risk infants who develop autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Hayley C. LEONARD, Auteur ; Rachael BEDFORD, Auteur ; Andrew PICKLES, Auteur ; Elisabeth L. HILL, Auteur Article en page(s) : p.15-24 Langues : Anglais (eng) Mots-clés : Motor development  Autism spectrum disorder  Infancy  Language development  Prospective Index. décimale : PER Périodiques Résumé : Abstract The aim of the current paper was to use data from a prospective study to assess the impact of early motor skills on the rate of language development in infants with an older sibling with autism spectrum disorder (ASD), who are at increased risk of developing ASD themselves. Infants were tested prospectively at four points (7, 14, 24 and 36 months), and were assessed for ASD at the last visit. Latent growth curve analysis was used to model rate of language development using the Vineland Adaptive Behavior Scales between 7–36 months in infants at high and low familial risk for ASD. Motor scores from the Mullen Scales of Early Learning at 7 months were used as predictors of language growth. Gross Motor scores predicted the subsequent rate of expressive, but not receptive, language development in at-risk siblings who were later diagnosed with ASD. Although the pattern was similar for fine motor skills, the relationship did not reach significance. It seems that early motor delay impacts the rate of development of expressive language, and this may be of particular importance to infants at increased risk of developing ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Predicting the rate of language development from early motor skills in at-risk infants who develop autism spectrum disorder [Texte imprimé et/ou numérique] / Hayley C. LEONARD, Auteur ; Rachael BEDFORD, Auteur ; Andrew PICKLES, Auteur ; Elisabeth L. HILL, Auteur . - p.15-24. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 13-14 (May 2015) . - p.15-24 Mots-clés : Motor development  Autism spectrum disorder  Infancy  Language development  Prospective Index. décimale : PER Périodiques Résumé : Abstract The aim of the current paper was to use data from a prospective study to assess the impact of early motor skills on the rate of language development in infants with an older sibling with autism spectrum disorder (ASD), who are at increased risk of developing ASD themselves. Infants were tested prospectively at four points (7, 14, 24 and 36 months), and were assessed for ASD at the last visit. Latent growth curve analysis was used to model rate of language development using the Vineland Adaptive Behavior Scales between 7–36 months in infants at high and low familial risk for ASD. Motor scores from the Mullen Scales of Early Learning at 7 months were used as predictors of language growth. Gross Motor scores predicted the subsequent rate of expressive, but not receptive, language development in at-risk siblings who were later diagnosed with ASD. Although the pattern was similar for fine motor skills, the relationship did not reach significance. It seems that early motor delay impacts the rate of development of expressive language, and this may be of particular importance to infants at increased risk of developing ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Prosocial skills in young children with autism, and their mothers’ psychological well-being: Longitudinal relationships / Vasiliki TOTSIKA in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 13-14 (May 2015) . - p.25-31 Titre : Prosocial skills in young children with autism, and their mothers’ psychological well-being: Longitudinal relationships Type de document : Texte imprimé et/ou numérique Auteurs : Vasiliki TOTSIKA, Auteur ; Richard P. HASTINGS, Auteur ; Eric EMERSON, Auteur ; Damon M. BERRIDGE, Auteur ; Gillian A. LANCASTER, Auteur Article en page(s) : p.25-31 Langues : Anglais (eng) Mots-clés : Autism  Prosocial skills  Distress  Life satisfaction  Bidirectional Index. décimale : PER Périodiques Résumé : Abstract The study aimed to explore the longitudinal association between prosocial skills in young children with an ASD and maternal psychological well-being. Participants were 132 children with autism drawn from the British Millennium Cohort Study (aged 9 months, 3 and 5 years). Three-wave cross-lagged structural equation models tested whether children's prosocial skills were reciprocally related to maternal psychological distress and life satisfaction. Findings indicated that relationships were not bidirectional, as both maternal outcomes were not associated with children's prosocial skills two years later. However, prosocial skills at 3 years were associated with improved maternal well-being (less distress and more life satisfaction) when children were 5-years-old. The study adds to the limited evidence base on bidirectional relationships between prosocial skills in ASD and proximal environmental variables. Findings highlight the importance of testing for reciprocal relationships rather than assuming unidirectional effects. In addition, they indicate that other-directed behaviors in children with autism have the potential to boost maternal well-being. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.01.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Prosocial skills in young children with autism, and their mothers’ psychological well-being: Longitudinal relationships [Texte imprimé et/ou numérique] / Vasiliki TOTSIKA, Auteur ; Richard P. HASTINGS, Auteur ; Eric EMERSON, Auteur ; Damon M. BERRIDGE, Auteur ; Gillian A. LANCASTER, Auteur . - p.25-31. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 13-14 (May 2015) . - p.25-31 Mots-clés : Autism  Prosocial skills  Distress  Life satisfaction  Bidirectional Index. décimale : PER Périodiques Résumé : Abstract The study aimed to explore the longitudinal association between prosocial skills in young children with an ASD and maternal psychological well-being. Participants were 132 children with autism drawn from the British Millennium Cohort Study (aged 9 months, 3 and 5 years). Three-wave cross-lagged structural equation models tested whether children's prosocial skills were reciprocally related to maternal psychological distress and life satisfaction. Findings indicated that relationships were not bidirectional, as both maternal outcomes were not associated with children's prosocial skills two years later. However, prosocial skills at 3 years were associated with improved maternal well-being (less distress and more life satisfaction) when children were 5-years-old. The study adds to the limited evidence base on bidirectional relationships between prosocial skills in ASD and proximal environmental variables. Findings highlight the importance of testing for reciprocal relationships rather than assuming unidirectional effects. In addition, they indicate that other-directed behaviors in children with autism have the potential to boost maternal well-being. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.01.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Voluntary attention in Asperger's syndrome: Brain electrical oscillation and phase-synchronization during facial emotion recognition / Yi-Li TSENG in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 13-14 (May 2015) . - p.32-51 Titre : Voluntary attention in Asperger's syndrome: Brain electrical oscillation and phase-synchronization during facial emotion recognition Type de document : Texte imprimé et/ou numérique Auteurs : Yi-Li TSENG, Auteur ; Han Hsuan YANG, Auteur ; Alexander N. SAVOSTYANOV, Auteur ; Vincent S. C. CHIEN, Auteur ; Michelle LIOU, Auteur Article en page(s) : p.32-51 Langues : Anglais (eng) Mots-clés : Asperger syndrome  EEG  Facial emotion recognition  Spatial frequency  Event-related spectral perturbations (ERSP)  Phase synchronization Index. décimale : PER Périodiques Résumé : Abstract This study investigated electroencephalography (EEG) oscillatory activity and phase-synchronization in patients with Asperger's syndrome (AS) during visual recognition of emotional faces. In the experiment, 10 AS adults (2 females, age 19.6 ± 1.96) and 10 IQ-matched controls (3 females, age 24.4 ± 3.24) participated in tasks involving emotionality evaluation of either photograph or line-drawing faces. Emotional faces elicited comparable reaction times and evaluation scores between the two groups. In the photograph task, the AS group had no visible N400 component and lower delta/theta synchronization (350–450 ms post-stimulus onset) in the temporal and occipital–parietal regions, and much weaker phase synchronization between distant scalp regions (200–500 ms post-stimulus onset) compared with the control group. In the line-drawing task, the two groups had the same degree of delta/theta synchronization in the central and occipital–parietal regions and comparable phase synchronization between scalp regions. We conclude by hypothesizing that AS patients might have structural deficits in the amygdala and its related limbic structures, a site critical for recognition of emotional faces beyond conscious awareness, but that they preserve the intact function in the cognitive pathway to keep up comparable behavioral performances with the healthy controls through voluntary control of attention. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.01.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Voluntary attention in Asperger's syndrome: Brain electrical oscillation and phase-synchronization during facial emotion recognition [Texte imprimé et/ou numérique] / Yi-Li TSENG, Auteur ; Han Hsuan YANG, Auteur ; Alexander N. SAVOSTYANOV, Auteur ; Vincent S. C. CHIEN, Auteur ; Michelle LIOU, Auteur . - p.32-51. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 13-14 (May 2015) . - p.32-51 Mots-clés : Asperger syndrome  EEG  Facial emotion recognition  Spatial frequency  Event-related spectral perturbations (ERSP)  Phase synchronization Index. décimale : PER Périodiques Résumé : Abstract This study investigated electroencephalography (EEG) oscillatory activity and phase-synchronization in patients with Asperger's syndrome (AS) during visual recognition of emotional faces. In the experiment, 10 AS adults (2 females, age 19.6 ± 1.96) and 10 IQ-matched controls (3 females, age 24.4 ± 3.24) participated in tasks involving emotionality evaluation of either photograph or line-drawing faces. Emotional faces elicited comparable reaction times and evaluation scores between the two groups. In the photograph task, the AS group had no visible N400 component and lower delta/theta synchronization (350–450 ms post-stimulus onset) in the temporal and occipital–parietal regions, and much weaker phase synchronization between distant scalp regions (200–500 ms post-stimulus onset) compared with the control group. In the line-drawing task, the two groups had the same degree of delta/theta synchronization in the central and occipital–parietal regions and comparable phase synchronization between scalp regions. We conclude by hypothesizing that AS patients might have structural deficits in the amygdala and its related limbic structures, a site critical for recognition of emotional faces beyond conscious awareness, but that they preserve the intact function in the cognitive pathway to keep up comparable behavioral performances with the healthy controls through voluntary control of attention. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.01.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260