A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders / Hjördis Osk ATLADOTTIR in Journal of Autism and Developmental Disorders, 45-8 (August 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2429-2442 Titre : A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Erik T. PARNER, Auteur ; T. B. HENRIKSEN, Auteur Année de publication : 2015 Article en page(s) : p.2429-2442 Langues : Anglais (eng) Mots-clés : Autism  Neonatal  Hyperkinetic disorder  CP  Epilepsy  Intellectual disability Index. décimale : PER Périodiques Résumé : The aim of this study was to describe the profile of specific neonatal morbidities in children later diagnosed with autism spectrum disorder (ASD), and to compare this profile with the profile of children with hyperkinetic disorder, cerebral palsy, epilepsy or intellectual disability. This is a Danish population based cohort study, including all children born in Denmark from 1994, through 2010, and surviving the first year of life. Children with ASD as a whole have significantly elevated rates of a range of neurologic, respiratory, inflammatory, and metabolic problems in the neonatal period compared to the general population, but there are few if any indicators of a distinctive neonatal morbidity profile in ASD compared to other neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1007/s10803-015-2408-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 [article] A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders [Texte imprimé et/ou numérique] / Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Erik T. PARNER, Auteur ; T. B. HENRIKSEN, Auteur . - 2015 . - p.2429-2442. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2429-2442 Mots-clés : Autism  Neonatal  Hyperkinetic disorder  CP  Epilepsy  Intellectual disability Index. décimale : PER Périodiques Résumé : The aim of this study was to describe the profile of specific neonatal morbidities in children later diagnosed with autism spectrum disorder (ASD), and to compare this profile with the profile of children with hyperkinetic disorder, cerebral palsy, epilepsy or intellectual disability. This is a Danish population based cohort study, including all children born in Denmark from 1994, through 2010, and surviving the first year of life. Children with ASD as a whole have significantly elevated rates of a range of neurologic, respiratory, inflammatory, and metabolic problems in the neonatal period compared to the general population, but there are few if any indicators of a distinctive neonatal morbidity profile in ASD compared to other neurodevelopmental outcomes. En ligne : http://dx.doi.org/10.1007/s10803-015-2408-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263

Gestational Age and Autism Spectrum Disorder: Trends in Risk Over Time / Hjördis Osk ATLADOTTIR in Autism Research, 9-2 (February 2016)  

Public ISBD [article]  inAutism Research > 9-2 (February 2016) . - p.224-231 Titre : Gestational Age and Autism Spectrum Disorder: Trends in Risk Over Time Type de document : Texte imprimé et/ou numérique Auteurs : Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; T. B. HENRIKSEN, Auteur ; L. HJORT, Auteur ; Erik T. PARNER, Auteur Article en page(s) : p.224-231 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  autism  gestational age  preterm birth  time trend Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is a serious neurodevelopmental disorder. Several previous studies have identified preterm birth as a risk factor for ASD but none has studied whether the association between gestational age and ASD has changed over time. This is a Danish population-based follow-up study including live-born singletons born in Denmark between 1980 and 2009, identified in the Danish Medical Birth Registry, a study population of 1,775,397 children. We used a Cox regression model combined with spline to study the risk for ASD by gestational age across three decades of birth cohorts. We included 19,020 children diagnosed with ASD. Across all birth year cohorts, we found that the risk of being diagnosed with ASD increased with lower gestational age (P-value: <0.01). Across all gestational weeks, we found a statistically significant higher risk estimates in birth cohort 1980 to 1989, compared to birth cohorts 1990 to 1999 and 2000 to 2009, respectively. No statistically significant difference in risk estimates was observed between birth cohort 1990 to 1999 and 2000 to 2009. The observed time trend in risk of ASD after preterm birth may reflect: (1) a change in the risk profile of persons with ASD due to the broadening of ASD diagnostic criteria over time; or (2) improved neonatal care for low GA infants, which has reduced risk of adverse outcomes like ASD in preterm children. En ligne : http://dx.doi.org/10.1002/aur.1525 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282 [article] Gestational Age and Autism Spectrum Disorder: Trends in Risk Over Time [Texte imprimé et/ou numérique] / Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; T. B. HENRIKSEN, Auteur ; L. HJORT, Auteur ; Erik T. PARNER, Auteur . - p.224-231. Langues : Anglais (eng) in Autism Research > 9-2 (February 2016) . - p.224-231 Mots-clés : autism spectrum disorder  autism  gestational age  preterm birth  time trend Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is a serious neurodevelopmental disorder. Several previous studies have identified preterm birth as a risk factor for ASD but none has studied whether the association between gestational age and ASD has changed over time. This is a Danish population-based follow-up study including live-born singletons born in Denmark between 1980 and 2009, identified in the Danish Medical Birth Registry, a study population of 1,775,397 children. We used a Cox regression model combined with spline to study the risk for ASD by gestational age across three decades of birth cohorts. We included 19,020 children diagnosed with ASD. Across all birth year cohorts, we found that the risk of being diagnosed with ASD increased with lower gestational age (P-value: <0.01). Across all gestational weeks, we found a statistically significant higher risk estimates in birth cohort 1980 to 1989, compared to birth cohorts 1990 to 1999 and 2000 to 2009, respectively. No statistically significant difference in risk estimates was observed between birth cohort 1990 to 1999 and 2000 to 2009. The observed time trend in risk of ASD after preterm birth may reflect: (1) a change in the risk profile of persons with ASD due to the broadening of ASD diagnostic criteria over time; or (2) improved neonatal care for low GA infants, which has reduced risk of adverse outcomes like ASD in preterm children. En ligne : http://dx.doi.org/10.1002/aur.1525 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282

Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders / Hjördis Osk ATLADOTTIR in Journal of Autism and Developmental Disorders, 40-12 (December 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-12 (December 2010) . - p.1423-1430 Titre : Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hjördis Osk ATLADOTTIR, Auteur ; Poul THORSEN, Auteur ; Lars OSTERGAARD, Auteur ; Diana SCHENDEL, Auteur ; Sanne LEMCKE, Auteur ; Morsi W. ABDALLAH, Auteur ; Erik T. PARNER, Auteur Année de publication : 2010 Article en page(s) : p.1423-1430 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autism  Infection  Influenza  Prenatal infection  Maternal infection Index. décimale : PER Périodiques Résumé : Exposure to prenatal infection has been suggested to cause deficiencies in fetal neurodevelopment. In this study we included all children born in Denmark from 1980, through 2005. Diagnoses of autism spectrum disorders (ASDs) and maternal infection were obtained through nationwide registers. Data was analyzed using Cox proportional hazards regression. No association was found between any maternal infection and diagnosis of ASDs in the child when looking at the total period of pregnancy: adjusted hazard ratio = 1.14 (CI: 0.96–1.34). However, admission to hospital due to maternal viral infection in the first trimester and maternal bacterial infection in the second trimester were found to be associated with diagnosis of ASDs in the offspring, adjusted hazard ratio = 2.98 (CI: 1.29–7.15) and adjusted hazard ratio = 1.42 (CI: 1.08–1.87), respectively. Our results support prior hypotheses concerning early prenatal viral infection increasing the risk of ASDs. En ligne : http://dx.doi.org/10.1007/s10803-010-1006-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114 [article] Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Hjördis Osk ATLADOTTIR, Auteur ; Poul THORSEN, Auteur ; Lars OSTERGAARD, Auteur ; Diana SCHENDEL, Auteur ; Sanne LEMCKE, Auteur ; Morsi W. ABDALLAH, Auteur ; Erik T. PARNER, Auteur . - 2010 . - p.1423-1430. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-12 (December 2010) . - p.1423-1430 Mots-clés : Autism spectrum disorder  Autism  Infection  Influenza  Prenatal infection  Maternal infection Index. décimale : PER Périodiques Résumé : Exposure to prenatal infection has been suggested to cause deficiencies in fetal neurodevelopment. In this study we included all children born in Denmark from 1980, through 2005. Diagnoses of autism spectrum disorders (ASDs) and maternal infection were obtained through nationwide registers. Data was analyzed using Cox proportional hazards regression. No association was found between any maternal infection and diagnosis of ASDs in the child when looking at the total period of pregnancy: adjusted hazard ratio = 1.14 (CI: 0.96–1.34). However, admission to hospital due to maternal viral infection in the first trimester and maternal bacterial infection in the second trimester were found to be associated with diagnosis of ASDs in the offspring, adjusted hazard ratio = 2.98 (CI: 1.29–7.15) and adjusted hazard ratio = 1.42 (CI: 1.08–1.87), respectively. Our results support prior hypotheses concerning early prenatal viral infection increasing the risk of ASDs. En ligne : http://dx.doi.org/10.1007/s10803-010-1006-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114

Patterns of Contact with Hospital for Children with an Autism Spectrum Disorder: A Danish Register-Based Study / Hjördis Osk ATLADOTTIR in Journal of Autism and Developmental Disorders, 42-8 (August 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1717-1728 Titre : Patterns of Contact with Hospital for Children with an Autism Spectrum Disorder: A Danish Register-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Marlene B. LAURITSEN, Auteur ; Tine Brink HENRIKSEN, Auteur ; Erik T. PARNER, Auteur Année de publication : 2012 Article en page(s) : p.1717-1728 Langues : Anglais (eng) Mots-clés : Autistic disorder  Autism  Hospitalization  Admission  Hospital contact  Comorbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to study patterns of contact with hospital for children with autism spectrum disorder (ASD) using Danish population based register data. We included all children born in Denmark from 1994 through 2002. We found that children diagnosed with ASD had an increased rate of contact with hospital, almost regardless of the cause for the hospital contact. Given the overall association between hospital contact for various causes and ASD observed in these data, hospital data should be used cautiously in future studies searching for associations between a specific disease and ASD. If the increased rate of hospital contact overall for children with ASD is not considered, then misleading over interpretations might be made of observed associations between specific diseases and ASD. En ligne : http://dx.doi.org/10.1007/s10803-011-1416-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Patterns of Contact with Hospital for Children with an Autism Spectrum Disorder: A Danish Register-Based Study [Texte imprimé et/ou numérique] / Hjördis Osk ATLADOTTIR, Auteur ; Diana SCHENDEL, Auteur ; Marlene B. LAURITSEN, Auteur ; Tine Brink HENRIKSEN, Auteur ; Erik T. PARNER, Auteur . - 2012 . - p.1717-1728. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1717-1728 Mots-clés : Autistic disorder  Autism  Hospitalization  Admission  Hospital contact  Comorbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to study patterns of contact with hospital for children with autism spectrum disorder (ASD) using Danish population based register data. We included all children born in Denmark from 1994 through 2002. We found that children diagnosed with ASD had an increased rate of contact with hospital, almost regardless of the cause for the hospital contact. Given the overall association between hospital contact for various causes and ASD observed in these data, hospital data should be used cautiously in future studies searching for associations between a specific disease and ASD. If the increased rate of hospital contact overall for children with ASD is not considered, then misleading over interpretations might be made of observed associations between specific diseases and ASD. En ligne : http://dx.doi.org/10.1007/s10803-011-1416-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

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