Erratum to: White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder / Miriam COOPER in Journal of Autism and Developmental Disorders, 44-11 (November 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2755-2755 Titre : Erratum to: White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder Type de document : texte imprimé Auteurs : Miriam COOPER, Auteur ; Anita THAPAR, Auteur ; Derek K. JONES, Auteur Article en page(s) : p.2755-2755 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-014-2162-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Erratum to: White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder [texte imprimé] / Miriam COOPER, Auteur ; Anita THAPAR, Auteur ; Derek K. JONES, Auteur . - p.2755-2755. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2755-2755 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-014-2162-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Erratum : White matter integrity in Asperger syndrome: A preliminary diffusion tensor magnetic resonance imaging study in adults / Oswald J.N. BLOEMEN in Autism Research, 4-2 (April 2011)  

Public ISBD [article]  inAutism Research > 4-2 (April 2011) . - p.160 Titre : Erratum : White matter integrity in Asperger syndrome: A preliminary diffusion tensor magnetic resonance imaging study in adults Type de document : texte imprimé Auteurs : Oswald J.N. BLOEMEN, Auteur ; Quinton DEELEY, Auteur ; Fred SUNDRAM, Auteur ; Eileen DALY, Auteur ; Gareth J. BARKER, Auteur ; Derek K. JONES, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Nicole SCHMITZ, Auteur ; Dene ROBERTSON, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur Année de publication : 2011 Article en page(s) : p.160 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.189 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Erratum : White matter integrity in Asperger syndrome: A preliminary diffusion tensor magnetic resonance imaging study in adults [texte imprimé] / Oswald J.N. BLOEMEN, Auteur ; Quinton DEELEY, Auteur ; Fred SUNDRAM, Auteur ; Eileen DALY, Auteur ; Gareth J. BARKER, Auteur ; Derek K. JONES, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Nicole SCHMITZ, Auteur ; Dene ROBERTSON, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur . - 2011 . - p.160. Langues : Anglais (eng) in Autism Research > 4-2 (April 2011) . - p.160 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.189 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adults / Oswald J.N. BLOEMEN in Autism Research, 3-5 (October 2010)  

Public ISBD [article]  inAutism Research > 3-5 (October 2010) . - p.203-213 Titre : White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adults Type de document : texte imprimé Auteurs : Oswald J.N. BLOEMEN, Auteur ; Quinton DEELEY, Auteur ; Fred SUNDRAM, Auteur ; Eileen DALY, Auteur ; Gareth J. BARKER, Auteur ; Derek K. JONES, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Nicole SCHMITZ, Auteur ; Dene ROBERTSON, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur Année de publication : 2010 Article en page(s) : p.203-213 Langues : Anglais (eng) Mots-clés : autism  Asperger syndrome  white matter  DTI  connectivity Index. décimale : PER Périodiques Résumé : Background: Autistic Spectrum Disorder (ASD), including Asperger syndrome and autism, is a highly genetic neurodevelopmental disorder. There is a consensus that ASD has a biological basis, and it has been proposed that it is a “connectivity” disorder. Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) allows measurement of the microstructural integrity of white matter (a proxy measure of “connectivity”). However, nobody has investigated the microstructural integrity of whole brain white matter in people with Asperger syndrome. Methods: We measured the fractional anisotropy (FA), mean diffusivity (MD) and radial diffusivity (RD) of white matter, using DT-MRI, in 13 adults with Asperger syndrome and 13 controls. The groups did not differ significantly in overall intelligence and age. FA, MD and RD were assessed using whole brain voxel-based techniques. Results: Adults with Asperger syndrome had a significantly lower FA than controls in 13 clusters. These were largely bilateral and included white matter in the internal capsule, frontal, temporal, parietal and occipital lobes, cingulum and corpus callosum. Conclusions: Adults with Asperger syndrome have widespread significant differences from controls in white matter microstructural integrity. En ligne : http://dx.doi.org/10.1002/aur.146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115 [article] White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adults [texte imprimé] / Oswald J.N. BLOEMEN, Auteur ; Quinton DEELEY, Auteur ; Fred SUNDRAM, Auteur ; Eileen DALY, Auteur ; Gareth J. BARKER, Auteur ; Derek K. JONES, Auteur ; Therese A.M.J. VAN AMELSVOORT, Auteur ; Nicole SCHMITZ, Auteur ; Dene ROBERTSON, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur . - 2010 . - p.203-213. Langues : Anglais (eng) in Autism Research > 3-5 (October 2010) . - p.203-213 Mots-clés : autism  Asperger syndrome  white matter  DTI  connectivity Index. décimale : PER Périodiques Résumé : Background: Autistic Spectrum Disorder (ASD), including Asperger syndrome and autism, is a highly genetic neurodevelopmental disorder. There is a consensus that ASD has a biological basis, and it has been proposed that it is a “connectivity” disorder. Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) allows measurement of the microstructural integrity of white matter (a proxy measure of “connectivity”). However, nobody has investigated the microstructural integrity of whole brain white matter in people with Asperger syndrome. Methods: We measured the fractional anisotropy (FA), mean diffusivity (MD) and radial diffusivity (RD) of white matter, using DT-MRI, in 13 adults with Asperger syndrome and 13 controls. The groups did not differ significantly in overall intelligence and age. FA, MD and RD were assessed using whole brain voxel-based techniques. Results: Adults with Asperger syndrome had a significantly lower FA than controls in 13 clusters. These were largely bilateral and included white matter in the internal capsule, frontal, temporal, parietal and occipital lobes, cingulum and corpus callosum. Conclusions: Adults with Asperger syndrome have widespread significant differences from controls in white matter microstructural integrity. En ligne : http://dx.doi.org/10.1002/aur.146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115

White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescents / F. SUNDRAM in Journal of Neurodevelopmental Disorders, 2-2 (June 2010)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 2-2 (June 2010) . - p.77-92 Titre : White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescents Type de document : texte imprimé Auteurs : F. SUNDRAM, Auteur ; Linda E. CAMPBELL, Auteur ; Rayna AZUMA, Auteur ; Eileen DALY, Auteur ; Oswald J.N. BLOEMEN, Auteur ; Gareth J. BARKER, Auteur ; Xavier CHITNIS, Auteur ; Derek K. JONES, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur Article en page(s) : p.77-92 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Young people with 22q11 Deletion Syndrome (22q11DS) are at substantial risk for developing psychosis and have significant differences in white matter (WM) volume. However, there are few in vivo studies of both WM microstructural integrity (as measured using Diffusion Tensor (DT)-MRI) and WM volume in the same individual. We used DT-MRI and structural MRI (sMRI) with voxel based morphometry (VBM) to compare, respectively, the fractional anisotropy (FA) and WM volume of 11 children and adolescents with 22q11DS and 12 controls. Also, within 22q11DS we related differences in WM to severity of schizotypy, and polymorphism of the catechol-O-methyltransferase (COMT) gene. People with 22q11DS had significantly lower FA in inter-hemispheric and brainstem and frontal, parietal and temporal lobe regions after covarying for IQ. Significant WM volumetric increases were found in the internal capsule, anterior brainstem and frontal and occipital lobes. There was a significant negative correlation between increased schizotypy scores and reduced WM FA in the right posterior limb of internal capsule and the right body and left splenium of corpus callosum. Finally, the Val allele of COMT was associated with a significant reduction in both FA and volume of WM in the frontal lobes, cingulum and corpus callosum. Young people with 22q11DS have significant differences in both WM microstructure and volume. Also, there is preliminary evidence that within 22q11DS, some regional differences in FA are associated with allelic variation in COMT and may perhaps also be associated with schizotypy. En ligne : http://dx.doi.org/10.1007/s11689-010-9043-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342 [article] White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescents [texte imprimé] / F. SUNDRAM, Auteur ; Linda E. CAMPBELL, Auteur ; Rayna AZUMA, Auteur ; Eileen DALY, Auteur ; Oswald J.N. BLOEMEN, Auteur ; Gareth J. BARKER, Auteur ; Xavier CHITNIS, Auteur ; Derek K. JONES, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Kieran C. MURPHY, Auteur ; Declan G.M. MURPHY, Auteur . - p.77-92. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 2-2 (June 2010) . - p.77-92 Index. décimale : PER Périodiques Résumé : Young people with 22q11 Deletion Syndrome (22q11DS) are at substantial risk for developing psychosis and have significant differences in white matter (WM) volume. However, there are few in vivo studies of both WM microstructural integrity (as measured using Diffusion Tensor (DT)-MRI) and WM volume in the same individual. We used DT-MRI and structural MRI (sMRI) with voxel based morphometry (VBM) to compare, respectively, the fractional anisotropy (FA) and WM volume of 11 children and adolescents with 22q11DS and 12 controls. Also, within 22q11DS we related differences in WM to severity of schizotypy, and polymorphism of the catechol-O-methyltransferase (COMT) gene. People with 22q11DS had significantly lower FA in inter-hemispheric and brainstem and frontal, parietal and temporal lobe regions after covarying for IQ. Significant WM volumetric increases were found in the internal capsule, anterior brainstem and frontal and occipital lobes. There was a significant negative correlation between increased schizotypy scores and reduced WM FA in the right posterior limb of internal capsule and the right body and left splenium of corpus callosum. Finally, the Val allele of COMT was associated with a significant reduction in both FA and volume of WM in the frontal lobes, cingulum and corpus callosum. Young people with 22q11DS have significant differences in both WM microstructure and volume. Also, there is preliminary evidence that within 22q11DS, some regional differences in FA are associated with allelic variation in COMT and may perhaps also be associated with schizotypy. En ligne : http://dx.doi.org/10.1007/s11689-010-9043-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342

White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder / Miriam COOPER in Journal of Autism and Developmental Disorders, 44-11 (November 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2742-2754 Titre : White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder Type de document : texte imprimé Auteurs : Miriam COOPER, Auteur ; Anita THAPAR, Auteur ; Derek K. JONES, Auteur Article en page(s) : p.2742-2754 Langues : Anglais (eng) Mots-clés : Diffusion MRI  ADHD  ASD  White matter  Tract-based spatial statistics  RESTORE Index. décimale : PER Périodiques Résumé : Traits of autism spectrum disorder (ASD) in children with attention-deficit/hyperactivity disorder (ADHD) have previously been found to index clinical severity. This study examined the association of ASD traits with diffusion parameters in adolescent males with ADHD (n = 17), and also compared WM microstructure relative to controls (n = 17). Significant associations (p 0.05, corrected) were found between fractional anisotropy/radial diffusivity and ASD trait severity (positive and negative correlations respectively), mostly in the right posterior limb of the internal capsule/corticospinal tract, right cerebellar peduncle and the midbrain. No case–control differences were found for the diffusion parameters investigated. This is the first report of a WM microstructural signature of autistic traits in ADHD. Thus, even in the absence of full disorder, ASD traits may index a distinctive underlying neurobiology in ADHD. En ligne : http://dx.doi.org/10.1007/s10803-014-2131-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] White Matter Microstructure Predicts Autistic Traits in Attention-Deficit/Hyperactivity Disorder [texte imprimé] / Miriam COOPER, Auteur ; Anita THAPAR, Auteur ; Derek K. JONES, Auteur . - p.2742-2754. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2742-2754 Mots-clés : Diffusion MRI  ADHD  ASD  White matter  Tract-based spatial statistics  RESTORE Index. décimale : PER Périodiques Résumé : Traits of autism spectrum disorder (ASD) in children with attention-deficit/hyperactivity disorder (ADHD) have previously been found to index clinical severity. This study examined the association of ASD traits with diffusion parameters in adolescent males with ADHD (n = 17), and also compared WM microstructure relative to controls (n = 17). Significant associations (p 0.05, corrected) were found between fractional anisotropy/radial diffusivity and ASD trait severity (positive and negative correlations respectively), mostly in the right posterior limb of the internal capsule/corticospinal tract, right cerebellar peduncle and the midbrain. No case–control differences were found for the diffusion parameters investigated. This is the first report of a WM microstructural signature of autistic traits in ADHD. Thus, even in the absence of full disorder, ASD traits may index a distinctive underlying neurobiology in ADHD. En ligne : http://dx.doi.org/10.1007/s10803-014-2131-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

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