Autism Spectrum Disorder Risk Factors and Autistic Traits in Gender Dysphoric Children / Doug P. VANDERLAAN in Journal of Autism and Developmental Disorders, 45-6 (June 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1742-1750 Titre : Autism Spectrum Disorder Risk Factors and Autistic Traits in Gender Dysphoric Children Type de document : Texte imprimé et/ou numérique Auteurs : Doug P. VANDERLAAN, Auteur ; Jonathan H. LEEF, Auteur ; Hayley WOOD, Auteur ; S. Kathleen HUGHES, Auteur ; Kenneth J. ZUCKER, Auteur Article en page(s) : p.1742-1750 Langues : Anglais (eng) Mots-clés : Gender dysphoria  Autism spectrum disorder  Birth weight  Parental age  Sibling sex ratio Index. décimale : PER Périodiques Résumé : Gender dysphoria (GD) and autism spectrum disorder (ASD) are associated. In 49 GD children (40 natal males), we examined ASD risk factors (i.e., birth weight, parental age, sibling sex ratio) in relation to autistic traits. Data were gathered on autistic traits, birth weight, parents’ ages at birth, sibling sex ratio, gender nonconformity, age, maternal depression, general behavioral and emotional problems, and IQ. High birth weight was associated with both high gender nonconformity and autistic traits among GD children. Developmental processes associated with high birth weight are, therefore, likely to underlie the GD–ASD link either directly or indirectly. The present study is the first to provide quantitative data bearing on possible mechanisms that lead GD and ASD to co-occur. En ligne : http://dx.doi.org/10.1007/s10803-014-2331-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Autism Spectrum Disorder Risk Factors and Autistic Traits in Gender Dysphoric Children [Texte imprimé et/ou numérique] / Doug P. VANDERLAAN, Auteur ; Jonathan H. LEEF, Auteur ; Hayley WOOD, Auteur ; S. Kathleen HUGHES, Auteur ; Kenneth J. ZUCKER, Auteur . - p.1742-1750. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1742-1750 Mots-clés : Gender dysphoria  Autism spectrum disorder  Birth weight  Parental age  Sibling sex ratio Index. décimale : PER Périodiques Résumé : Gender dysphoria (GD) and autism spectrum disorder (ASD) are associated. In 49 GD children (40 natal males), we examined ASD risk factors (i.e., birth weight, parental age, sibling sex ratio) in relation to autistic traits. Data were gathered on autistic traits, birth weight, parents’ ages at birth, sibling sex ratio, gender nonconformity, age, maternal depression, general behavioral and emotional problems, and IQ. High birth weight was associated with both high gender nonconformity and autistic traits among GD children. Developmental processes associated with high birth weight are, therefore, likely to underlie the GD–ASD link either directly or indirectly. The present study is the first to provide quantitative data bearing on possible mechanisms that lead GD and ASD to co-occur. En ligne : http://dx.doi.org/10.1007/s10803-014-2331-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

Gender diversity in a Chinese community sample and its associations with autism traits / Sylvia Yun SHI ; Hoi Ching LEI ; Cho Lam NGAN ; Doug P. VANDERLAAN ; Wang Ivy WONG in Autism Research, 17-7 (July 2024)  

Public ISBD [article]  inAutism Research > 17-7 (July 2024) . - p.1407-1416 Titre : Gender diversity in a Chinese community sample and its associations with autism traits Type de document : Texte imprimé et/ou numérique Auteurs : Sylvia Yun SHI, Auteur ; Hoi Ching LEI, Auteur ; Cho Lam NGAN, Auteur ; Doug P. VANDERLAAN, Auteur ; Wang Ivy WONG, Auteur Article en page(s) : p.1407-1416 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Emerging evidence suggests that gender dysphoria or gender diversity (GD) intersects frequently with autism spectrum disorder or autism traits. However, the magnitude and interpretation of this link continue to be debated. Most child studies on this topic were performed in clinical populations, and little is known about the generalizability of this co-occurrence to the broader community, especially to non-Western samples. Also, little is known about whether specific subdomains of autism are more strongly associated with GD. Therefore, we investigated GD and its association with autism traits in a Chinese community sample of 4-12-year-olds (N = 379; 51% birth-assigned girls). Parents provided information about GD characteristics using the standardized Gender Identity Questionnaire for Children and autism traits using the Chinese version of the Autism-Spectrum Quotient-Children. In addition, broader behavioral and emotional challenges were measured by the Behavior Problem Index (BPI) to account for psychological challenges other than autism traits. In this community sample of Chinese children, increased GD was associated with increased autism traits, even after accounting for the BPI. Of the four subscales, the Imagination and Patterns subscales in birth-assigned girls and the Imagination subscale in birth-assigned boys were especially associated with GD. These findings indicate that the association between GD and autism traits generalizes to a nonclinical, non-Western sample. Clinicians and researchers working with clinical as well as community children should thus pay attention to the co-occurrence of GD and autism traits, in and outside the West. En ligne : https://dx.doi.org/https://doi.org/10.1002/aur.3075 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533 [article] Gender diversity in a Chinese community sample and its associations with autism traits [Texte imprimé et/ou numérique] / Sylvia Yun SHI, Auteur ; Hoi Ching LEI, Auteur ; Cho Lam NGAN, Auteur ; Doug P. VANDERLAAN, Auteur ; Wang Ivy WONG, Auteur . - p.1407-1416. Langues : Anglais (eng) in Autism Research > 17-7 (July 2024) . - p.1407-1416 Index. décimale : PER Périodiques Résumé : Abstract Emerging evidence suggests that gender dysphoria or gender diversity (GD) intersects frequently with autism spectrum disorder or autism traits. However, the magnitude and interpretation of this link continue to be debated. Most child studies on this topic were performed in clinical populations, and little is known about the generalizability of this co-occurrence to the broader community, especially to non-Western samples. Also, little is known about whether specific subdomains of autism are more strongly associated with GD. Therefore, we investigated GD and its association with autism traits in a Chinese community sample of 4-12-year-olds (N = 379; 51% birth-assigned girls). Parents provided information about GD characteristics using the standardized Gender Identity Questionnaire for Children and autism traits using the Chinese version of the Autism-Spectrum Quotient-Children. In addition, broader behavioral and emotional challenges were measured by the Behavior Problem Index (BPI) to account for psychological challenges other than autism traits. In this community sample of Chinese children, increased GD was associated with increased autism traits, even after accounting for the BPI. Of the four subscales, the Imagination and Patterns subscales in birth-assigned girls and the Imagination subscale in birth-assigned boys were especially associated with GD. These findings indicate that the association between GD and autism traits generalizes to a nonclinical, non-Western sample. Clinicians and researchers working with clinical as well as community children should thus pay attention to the co-occurrence of GD and autism traits, in and outside the West. En ligne : https://dx.doi.org/https://doi.org/10.1002/aur.3075 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533

Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children / Evdokia ANAGNOSTOU ; Jason P. LERCH ; Margot J. TAYLOR ; Doug P. VANDERLAAN ; Peter SZATMARI ; Jennifer CROSBIE ; Robert NICOLSON ; Stelios GEORGIADIS ; Elizabeth KELLEY ; Muhammad AYUB ; Jessica BRIAN ; Meng-Chuan LAI ; Mark R. PALMERT in Journal of Child Psychology and Psychiatry, 65-9 (September 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-9 (September 2024) . - p.1223-1236 Titre : Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children Type de document : Texte imprimé et/ou numérique Auteurs : Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur ; Margot J. TAYLOR, Auteur ; Doug P. VANDERLAAN, Auteur ; Peter SZATMARI, Auteur ; Jennifer CROSBIE, Auteur ; Robert NICOLSON, Auteur ; Stelios GEORGIADIS, Auteur ; Elizabeth KELLEY, Auteur ; Muhammad AYUB, Auteur ; Jessica BRIAN, Auteur ; Meng-Chuan LAI, Auteur ; Mark R. PALMERT, Auteur Article en page(s) : p.1223-1236 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Gender clinic and single-item questionnaire-based data report increased co-occurrence of gender diversity and neurodevelopmental conditions. The nuances of these associations are under-studied. We used a transdiagnostic approach, combining categorical and dimensional characterization of neurodiversity, to further the understanding of its associations with gender diversity in identity and expression in children. Methods Data from 291 children (Autism N = 104, ADHD N = 104, Autism?+?ADHD N = 17, neurotypical N = 66) aged 4-12?years enrolled in the Province of Ontario Neurodevelopmental Network were analyzed. Gender diversity was measured multi-dimensionally using a well-validated parent-report instrument, the Gender Identity Questionnaire for Children (GIQC). We used gamma regression models to determine the significant correlates of gender diversity among age, puberty, sex-assigned-at-birth, categorical neurodevelopmental diagnoses, and dimensional neurodivergent traits (using the Social Communication Questionnaire and the Strengths and Weaknesses of ADHD Symptoms and Normal Behavior Rating Scales). Internalizing and externalizing problems were included as covariates. Results Neither a categorical diagnosis of autism nor ADHD significantly correlated with current GIQC-derived scores. Instead, higher early-childhood dimensional autistic social-communication traits correlated with higher current overall gender incongruence (as defined by GIQC-14 score). This correlation was potentially moderated by sex-assigned-at-birth: greater early-childhood autistic social-communication traits were associated with higher current overall gender incongruence in assigned-males-at-birth, but not assigned-females-at-birth. For fine-grained gender diversity domains, greater autistic restricted-repetitive behavior traits were associated with greater diversity in gender identity across sexes-assigned-at-birth; greater autistic social-communication traits were associated with lower stereotypical male expression across sexes-assigned-at-birth. Conclusions Dimensional autistic traits, rather than ADHD traits or categorical neurodevelopmental diagnoses, were associated with gender diversity domains across neurodivergent and neurotypical children. The association between early-childhood autistic social-communication traits and overall current gender diversity was most evident in assigned-males-at-birth. Nuanced interrelationships between neurodivergence and gender diversity should be better understood to clarify developmental links and to offer tailored support for neurodivergent and gender-diverse populations. En ligne : https://doi.org/10.1111/jcpp.13965 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children [Texte imprimé et/ou numérique] / Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur ; Margot J. TAYLOR, Auteur ; Doug P. VANDERLAAN, Auteur ; Peter SZATMARI, Auteur ; Jennifer CROSBIE, Auteur ; Robert NICOLSON, Auteur ; Stelios GEORGIADIS, Auteur ; Elizabeth KELLEY, Auteur ; Muhammad AYUB, Auteur ; Jessica BRIAN, Auteur ; Meng-Chuan LAI, Auteur ; Mark R. PALMERT, Auteur . - p.1223-1236. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-9 (September 2024) . - p.1223-1236 Index. décimale : PER Périodiques Résumé : Background Gender clinic and single-item questionnaire-based data report increased co-occurrence of gender diversity and neurodevelopmental conditions. The nuances of these associations are under-studied. We used a transdiagnostic approach, combining categorical and dimensional characterization of neurodiversity, to further the understanding of its associations with gender diversity in identity and expression in children. Methods Data from 291 children (Autism N = 104, ADHD N = 104, Autism?+?ADHD N = 17, neurotypical N = 66) aged 4-12?years enrolled in the Province of Ontario Neurodevelopmental Network were analyzed. Gender diversity was measured multi-dimensionally using a well-validated parent-report instrument, the Gender Identity Questionnaire for Children (GIQC). We used gamma regression models to determine the significant correlates of gender diversity among age, puberty, sex-assigned-at-birth, categorical neurodevelopmental diagnoses, and dimensional neurodivergent traits (using the Social Communication Questionnaire and the Strengths and Weaknesses of ADHD Symptoms and Normal Behavior Rating Scales). Internalizing and externalizing problems were included as covariates. Results Neither a categorical diagnosis of autism nor ADHD significantly correlated with current GIQC-derived scores. Instead, higher early-childhood dimensional autistic social-communication traits correlated with higher current overall gender incongruence (as defined by GIQC-14 score). This correlation was potentially moderated by sex-assigned-at-birth: greater early-childhood autistic social-communication traits were associated with higher current overall gender incongruence in assigned-males-at-birth, but not assigned-females-at-birth. For fine-grained gender diversity domains, greater autistic restricted-repetitive behavior traits were associated with greater diversity in gender identity across sexes-assigned-at-birth; greater autistic social-communication traits were associated with lower stereotypical male expression across sexes-assigned-at-birth. Conclusions Dimensional autistic traits, rather than ADHD traits or categorical neurodevelopmental diagnoses, were associated with gender diversity domains across neurodivergent and neurotypical children. The association between early-childhood autistic social-communication traits and overall current gender diversity was most evident in assigned-males-at-birth. Nuanced interrelationships between neurodivergence and gender diversity should be better understood to clarify developmental links and to offer tailored support for neurodivergent and gender-diverse populations. En ligne : https://doi.org/10.1111/jcpp.13965 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

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