Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample / Ellen VAN DER PLAS in Journal of Autism and Developmental Disorders, 46-9 (September 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3115-3125 Titre : Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample Type de document : Texte imprimé et/ou numérique Auteurs : Ellen VAN DER PLAS, Auteur ; Annie DUPUIS, Auteur ; Paul ARNOLD, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur Article en page(s) : p.3115-3125 Langues : Anglais (eng) Mots-clés : Autism  Attention/deficits hyperactivity disorder  Obsessive compulsive disorder  Familial  Traits  Community sample Index. décimale : PER Périodiques Résumé : We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The “sibling effect” on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only. En ligne : http://dx.doi.org/10.1007/s10803-016-2853-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 [article] Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample [Texte imprimé et/ou numérique] / Ellen VAN DER PLAS, Auteur ; Annie DUPUIS, Auteur ; Paul ARNOLD, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur . - p.3115-3125. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3115-3125 Mots-clés : Autism  Attention/deficits hyperactivity disorder  Obsessive compulsive disorder  Familial  Traits  Community sample Index. décimale : PER Périodiques Résumé : We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The “sibling effect” on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only. En ligne : http://dx.doi.org/10.1007/s10803-016-2853-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292

Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders / Elizabeth W. PANG in Autism Research, 16-3 (March 2023)  

Public ISBD [article]  inAutism Research > 16-3 (March 2023) . - p.535-542 Titre : Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth W. PANG, Auteur ; Chris HAMMILL, Auteur ; Margot J. TAYLOR, Auteur ; Jamie NEAR, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur ; Paul D. ARNOLD, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur Article en page(s) : p.535-542 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain. Recent evidence has shown the involvement of the cerebellum in cognition and affect regulation, and cerebellar atypical function or damage is reported frequently in NDDs. Magnetic resonance spectroscopy studies have reported decreases in GABA in cortical brain areas in the NDDs, however, GABA levels in the cerebellum have not been examined. To determine possible group effects, we used a MEGA-PRESS acquisition to investigate GABA+ levels in a cerebellar voxel in 343 individuals (aged 2.5-22?years) with ASD, ADHD, OCD and controls. Using a mixed effects model, we found no significant differences between groups in GABA+ concentration. Our findings suggest that cerebellar GABA+ levels do not differentiate NDD groups. En ligne : https://doi.org/10.1002/aur.2888 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498 [article] Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders [Texte imprimé et/ou numérique] / Elizabeth W. PANG, Auteur ; Chris HAMMILL, Auteur ; Margot J. TAYLOR, Auteur ; Jamie NEAR, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur ; Paul D. ARNOLD, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur . - p.535-542. Langues : Anglais (eng) in Autism Research > 16-3 (March 2023) . - p.535-542 Index. décimale : PER Périodiques Résumé : Abstract Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain. Recent evidence has shown the involvement of the cerebellum in cognition and affect regulation, and cerebellar atypical function or damage is reported frequently in NDDs. Magnetic resonance spectroscopy studies have reported decreases in GABA in cortical brain areas in the NDDs, however, GABA levels in the cerebellum have not been examined. To determine possible group effects, we used a MEGA-PRESS acquisition to investigate GABA+ levels in a cerebellar voxel in 343 individuals (aged 2.5-22?years) with ASD, ADHD, OCD and controls. Using a mixed effects model, we found no significant differences between groups in GABA+ concentration. Our findings suggest that cerebellar GABA+ levels do not differentiate NDD groups. En ligne : https://doi.org/10.1002/aur.2888 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498

Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample / Aneta D. KRAKOWSKI in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1534-1543 Titre : Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample Type de document : Texte imprimé et/ou numérique Auteurs : Aneta D. KRAKOWSKI, Auteur ; Katherine Tombeau COST, Auteur ; Peter SZATMARI, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Muhammad AYUB, Auteur ; Elizabeth KELLEY, Auteur ; Rob NICOLSON, Auteur ; Eleanor PULLENAYEGUM, Auteur ; Carolina BARNETT-TAPIA, Auteur Article en page(s) : p.1534-1543 Langues : Anglais (eng) Mots-clés : Humans  Attention Deficit Disorder with Hyperactivity/diagnosis/genetics  Autism Spectrum Disorder/diagnosis  Parents  Phenotype  Surveys and Questionnaires  Adhd  Asd  factor analysis  measurement invariance  measurement structure Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) have considerable overlap, supporting the need for a dimensional framework that examines neurodevelopmental domains which cross traditional diagnostic boundaries. In the following study, we use factor analysis to deconstruct the ASD-ADHD phenotype into its underlying phenotypic domains and test for measurement invariance across adaptive functioning, age, gender and ASD/ADHD clinical diagnoses. METHODS: Participants included children and youth (aged 3-20 years) with a clinical diagnosis of ASD (n=727) or ADHD (n=770) for a total of 1,497 participants. Parents of these children completed the Social Communication Questionnaire (SCQ), a measure of autism symptoms, and the Strengths and Weaknesses of ADHD and Normal Behaviour (SWAN) questionnaire, a measure of ADHD symptoms. An exploratory factor analysis (EFA) was performed on combined SCQ and SWAN items. This was followed by a confirmatory factor analysis (CFA) and tests of measurement invariance. RESULTS: EFA revealed a four-factor solution (inattention, hyperactivity/impulsivity, social-communication, and restricted, repetitive, behaviours and interests (RRBI)) and a CFA confirmed good model fit. This solution also showed good model fit across subgroups of interest. CONCLUSIONS: Our study shows that a combined ASD-ADHD phenotype is characterized by two latent ASD domains (social communication and RRBIs) and two latent ADHD domains (inattention and hyperactivity/impulsivity). We established measurement invariance of the derived measurement model across adaptive functioning, age, gender and ASD/ADHD diagnoses. En ligne : http://dx.doi.org/10.1111/jcpp.13609 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample [Texte imprimé et/ou numérique] / Aneta D. KRAKOWSKI, Auteur ; Katherine Tombeau COST, Auteur ; Peter SZATMARI, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Muhammad AYUB, Auteur ; Elizabeth KELLEY, Auteur ; Rob NICOLSON, Auteur ; Eleanor PULLENAYEGUM, Auteur ; Carolina BARNETT-TAPIA, Auteur . - p.1534-1543. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1534-1543 Mots-clés : Humans  Attention Deficit Disorder with Hyperactivity/diagnosis/genetics  Autism Spectrum Disorder/diagnosis  Parents  Phenotype  Surveys and Questionnaires  Adhd  Asd  factor analysis  measurement invariance  measurement structure Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) have considerable overlap, supporting the need for a dimensional framework that examines neurodevelopmental domains which cross traditional diagnostic boundaries. In the following study, we use factor analysis to deconstruct the ASD-ADHD phenotype into its underlying phenotypic domains and test for measurement invariance across adaptive functioning, age, gender and ASD/ADHD clinical diagnoses. METHODS: Participants included children and youth (aged 3-20 years) with a clinical diagnosis of ASD (n=727) or ADHD (n=770) for a total of 1,497 participants. Parents of these children completed the Social Communication Questionnaire (SCQ), a measure of autism symptoms, and the Strengths and Weaknesses of ADHD and Normal Behaviour (SWAN) questionnaire, a measure of ADHD symptoms. An exploratory factor analysis (EFA) was performed on combined SCQ and SWAN items. This was followed by a confirmatory factor analysis (CFA) and tests of measurement invariance. RESULTS: EFA revealed a four-factor solution (inattention, hyperactivity/impulsivity, social-communication, and restricted, repetitive, behaviours and interests (RRBI)) and a CFA confirmed good model fit. This solution also showed good model fit across subgroups of interest. CONCLUSIONS: Our study shows that a combined ASD-ADHD phenotype is characterized by two latent ASD domains (social communication and RRBIs) and two latent ADHD domains (inattention and hyperactivity/impulsivity). We established measurement invariance of the derived measurement model across adaptive functioning, age, gender and ASD/ADHD diagnoses. En ligne : http://dx.doi.org/10.1111/jcpp.13609 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores / Annie DUPUIS in Journal of Autism and Developmental Disorders, 51-5 (May 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1417-1427 Titre : Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores Type de document : Texte imprimé et/ou numérique Auteurs : Annie DUPUIS, Auteur ; Michael J. MOON, Auteur ; Jessica BRIAN, Auteur ; Stelios GEORGIADES, Auteur ; Tomer LEVY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rob NICOLSON, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur Article en page(s) : p.1417-1427 Langues : Anglais (eng) Mots-clés : Abas  Adaptive behaviors  Autism spectrum disorder  Children  Vineland Index. décimale : PER Périodiques Résumé : We examined the correlation between interviewer-administered Vineland Adaptive Behavior Scale II (VABS-II) and the parent-rated Adaptive Behavior Assessment System II (ABAS-II) questionnaire in 352 participants (ages 1.5-20.8 years) with autism spectrum disorder (ASD) to determine if ABAS could be used as a screen to reduce the number of VABS interviews. Corresponding domain scores between the two measures were highly correlated but scores were significantly lower on the ABAS-II. Screening with ABAS-II significantly reduced the number of VABS-II interviews required with little cost to overall accuracy. The ABAS-II provides a cost- and time-saving alternative to the VABS-II to rule out functional impairment; however, scores are not strictly comparable between the two measures. En ligne : http://dx.doi.org/10.1007/s10803-020-04597-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 [article] Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores [Texte imprimé et/ou numérique] / Annie DUPUIS, Auteur ; Michael J. MOON, Auteur ; Jessica BRIAN, Auteur ; Stelios GEORGIADES, Auteur ; Tomer LEVY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rob NICOLSON, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur . - p.1417-1427. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1417-1427 Mots-clés : Abas  Adaptive behaviors  Autism spectrum disorder  Children  Vineland Index. décimale : PER Périodiques Résumé : We examined the correlation between interviewer-administered Vineland Adaptive Behavior Scale II (VABS-II) and the parent-rated Adaptive Behavior Assessment System II (ABAS-II) questionnaire in 352 participants (ages 1.5-20.8 years) with autism spectrum disorder (ASD) to determine if ABAS could be used as a screen to reduce the number of VABS interviews. Corresponding domain scores between the two measures were highly correlated but scores were significantly lower on the ABAS-II. Screening with ABAS-II significantly reduced the number of VABS-II interviews required with little cost to overall accuracy. The ABAS-II provides a cost- and time-saving alternative to the VABS-II to rule out functional impairment; however, scores are not strictly comparable between the two measures. En ligne : http://dx.doi.org/10.1007/s10803-020-04597-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445

CRISIS AFAR: an international collaborative study of the impact of the COVID-19 pandemic on mental health and service access in youth with autism and neurodevelopmental conditions / Patricia SEGURA ; Louise GALLAGHER ; Stelios GEORGIADES ; Panagiota PERVANIDOU ; Audrey THURM ; Lindsay ALEXANDER ; Evdokia ANAGNOSTOU ; Yuta AOKI ; Catherine S. BIRKEN ; Somer L. BISHOP ; Jessica BOI ; Carmela BRAVACCIO ; Helena BRENTANI ; Paola CANEVINI ; Alessandra CARTA ; Alice CHARACH ; Antonella COSTANTINO ; Katherine T. COST ; Elaine A. CRAVO ; Jennifer CROSBIE ; Chiara DAVICO ; Federica DONNO ; Junya FUJINO ; Alessandra GABELLONE ; Cristiane T. GEYER ; Tomoya HIROTA ; Stephen KANNE ; Makiko KAWASHIMA ; Elizabeth KELLEY ; Hosanna KIM ; Young Shin KIM ; So Hyun KIM ; Daphne J. KORCZAK ; Meng-Chuan LAI ; Lucia MARGARI ; Lucia MARZULLI ; Gabriele MASI ; Luigi MAZZONE ; Jane MCGRATH ; Suneeta MONGA ; Paola MOROSINI ; Shinichiro NAKAJIMA ; Antonio NARZISI ; Rob NICOLSON ; Aki NIKOLAIDIS ; Yoshihiro NODA ; Kerri NOWELL ; Miriam POLIZZI ; Joana PORTOLESE ; Maria Pia RICCIO ; Manabu SAITO ; Ida SCHWARTZ ; Anish K. SIMHAL ; Martina SIRACUSANO ; Stefano SOTGIU ; Jacob STROUD ; Fernando SUMIYA ; Yoshiyuki TACHIBANA ; Nicole TAKAHASHI ; Riina TAKAHASHI ; Hiroki TAMON ; Raffaella TANCREDI ; Benedetto VITIELLO ; Alessandro ZUDDAS ; Bennett LEVENTHAL ; Kathleen MERIKANGAS ; Michael P. MILHAM ; Adriana DI MARTINO in Molecular Autism, 14 (2023)  

Public ISBD [article]  inMolecular Autism > 14 (2023) . - 7 p. Titre : CRISIS AFAR: an international collaborative study of the impact of the COVID-19 pandemic on mental health and service access in youth with autism and neurodevelopmental conditions Type de document : Texte imprimé et/ou numérique Auteurs : Patricia SEGURA, Auteur ; Louise GALLAGHER, Auteur ; Stelios GEORGIADES, Auteur ; Panagiota PERVANIDOU, Auteur ; Audrey THURM, Auteur ; Lindsay ALEXANDER, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Yuta AOKI, Auteur ; Catherine S. BIRKEN, Auteur ; Somer L. BISHOP, Auteur ; Jessica BOI, Auteur ; Carmela BRAVACCIO, Auteur ; Helena BRENTANI, Auteur ; Paola CANEVINI, Auteur ; Alessandra CARTA, Auteur ; Alice CHARACH, Auteur ; Antonella COSTANTINO, Auteur ; Katherine T. COST, Auteur ; Elaine A. CRAVO, Auteur ; Jennifer CROSBIE, Auteur ; Chiara DAVICO, Auteur ; Federica DONNO, Auteur ; Junya FUJINO, Auteur ; Alessandra GABELLONE, Auteur ; Cristiane T. GEYER, Auteur ; Tomoya HIROTA, Auteur ; Stephen KANNE, Auteur ; Makiko KAWASHIMA, Auteur ; Elizabeth KELLEY, Auteur ; Hosanna KIM, Auteur ; Young Shin KIM, Auteur ; So Hyun KIM, Auteur ; Daphne J. KORCZAK, Auteur ; Meng-Chuan LAI, Auteur ; Lucia MARGARI, Auteur ; Lucia MARZULLI, Auteur ; Gabriele MASI, Auteur ; Luigi MAZZONE, Auteur ; Jane MCGRATH, Auteur ; Suneeta MONGA, Auteur ; Paola MOROSINI, Auteur ; Shinichiro NAKAJIMA, Auteur ; Antonio NARZISI, Auteur ; Rob NICOLSON, Auteur ; Aki NIKOLAIDIS, Auteur ; Yoshihiro NODA, Auteur ; Kerri NOWELL, Auteur ; Miriam POLIZZI, Auteur ; Joana PORTOLESE, Auteur ; Maria Pia RICCIO, Auteur ; Manabu SAITO, Auteur ; Ida SCHWARTZ, Auteur ; Anish K. SIMHAL, Auteur ; Martina SIRACUSANO, Auteur ; Stefano SOTGIU, Auteur ; Jacob STROUD, Auteur ; Fernando SUMIYA, Auteur ; Yoshiyuki TACHIBANA, Auteur ; Nicole TAKAHASHI, Auteur ; Riina TAKAHASHI, Auteur ; Hiroki TAMON, Auteur ; Raffaella TANCREDI, Auteur ; Benedetto VITIELLO, Auteur ; Alessandro ZUDDAS, Auteur ; Bennett LEVENTHAL, Auteur ; Kathleen MERIKANGAS, Auteur ; Michael P. MILHAM, Auteur ; Adriana DI MARTINO, Auteur Article en page(s) : 7 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : BACKGROUND: Heterogeneous mental health outcomes during the COVID-19 pandemic are documented in the general population. Such heterogeneity has not been systematically assessed in youth with autism spectrum disorder (ASD) and related neurodevelopmental disorders (NDD). To identify distinct patterns of the pandemic impact and their predictors in ASD/NDD youth, we focused on pandemic-related changes in symptoms and access to services. METHODS: Using a naturalistic observational design, we assessed parent responses on the Coronavirus Health and Impact Survey Initiative (CRISIS) Adapted For Autism and Related neurodevelopmental conditions (AFAR). Cross-sectional AFAR data were aggregated across 14 European and North American sites yielding a clinically well-characterized sample of N=1275 individuals with ASD/NDD (age=11.0?+?3.6 years; n females=277). To identify subgroups with differential outcomes, we applied hierarchical clustering across eleven variables measuring changes in symptoms and access to services. Then, random forest classification assessed the importance of socio-demographics, pre-pandemic service rates, clinical severity of ASD-associated symptoms, and COVID-19 pandemic experiences/environments in predicting the outcome subgroups. RESULTS: Clustering revealed four subgroups. One subgroup-broad symptom worsening only (20%)-included youth with worsening across a range of symptoms but with service disruptions similar to the average of the aggregate sample. The other three subgroups were, relatively, clinically stable but differed in service access: primarily modified services (23%), primarily lost services (6%), and average services/symptom changes (53%). Distinct combinations of a set of pre-pandemic services, pandemic environment (e.g., COVID-19 new cases, restrictions), experiences (e.g., COVID-19 Worries), and age predicted each outcome subgroup. LIMITATIONS: Notable limitations of the study are its cross-sectional nature and focus on the first six months of the pandemic. CONCLUSIONS: Concomitantly assessing variation in changes of symptoms and service access during the first phase of the pandemic revealed differential outcome profiles in ASD/NDD youth. Subgroups were characterized by distinct prediction patterns across a set of pre- and pandemic-related experiences/contexts. Results may inform recovery efforts and preparedness in future crises; they also underscore the critical value of international data-sharing and collaborations to address the needs of those most vulnerable in times of crisis. En ligne : http://dx.doi.org/10.1186/s13229-022-00536-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513 [article] CRISIS AFAR: an international collaborative study of the impact of the COVID-19 pandemic on mental health and service access in youth with autism and neurodevelopmental conditions [Texte imprimé et/ou numérique] / Patricia SEGURA, Auteur ; Louise GALLAGHER, Auteur ; Stelios GEORGIADES, Auteur ; Panagiota PERVANIDOU, Auteur ; Audrey THURM, Auteur ; Lindsay ALEXANDER, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Yuta AOKI, Auteur ; Catherine S. BIRKEN, Auteur ; Somer L. BISHOP, Auteur ; Jessica BOI, Auteur ; Carmela BRAVACCIO, Auteur ; Helena BRENTANI, Auteur ; Paola CANEVINI, Auteur ; Alessandra CARTA, Auteur ; Alice CHARACH, Auteur ; Antonella COSTANTINO, Auteur ; Katherine T. COST, Auteur ; Elaine A. CRAVO, Auteur ; Jennifer CROSBIE, Auteur ; Chiara DAVICO, Auteur ; Federica DONNO, Auteur ; Junya FUJINO, Auteur ; Alessandra GABELLONE, Auteur ; Cristiane T. GEYER, Auteur ; Tomoya HIROTA, Auteur ; Stephen KANNE, Auteur ; Makiko KAWASHIMA, Auteur ; Elizabeth KELLEY, Auteur ; Hosanna KIM, Auteur ; Young Shin KIM, Auteur ; So Hyun KIM, Auteur ; Daphne J. KORCZAK, Auteur ; Meng-Chuan LAI, Auteur ; Lucia MARGARI, Auteur ; Lucia MARZULLI, Auteur ; Gabriele MASI, Auteur ; Luigi MAZZONE, Auteur ; Jane MCGRATH, Auteur ; Suneeta MONGA, Auteur ; Paola MOROSINI, Auteur ; Shinichiro NAKAJIMA, Auteur ; Antonio NARZISI, Auteur ; Rob NICOLSON, Auteur ; Aki NIKOLAIDIS, Auteur ; Yoshihiro NODA, Auteur ; Kerri NOWELL, Auteur ; Miriam POLIZZI, Auteur ; Joana PORTOLESE, Auteur ; Maria Pia RICCIO, Auteur ; Manabu SAITO, Auteur ; Ida SCHWARTZ, Auteur ; Anish K. SIMHAL, Auteur ; Martina SIRACUSANO, Auteur ; Stefano SOTGIU, Auteur ; Jacob STROUD, Auteur ; Fernando SUMIYA, Auteur ; Yoshiyuki TACHIBANA, Auteur ; Nicole TAKAHASHI, Auteur ; Riina TAKAHASHI, Auteur ; Hiroki TAMON, Auteur ; Raffaella TANCREDI, Auteur ; Benedetto VITIELLO, Auteur ; Alessandro ZUDDAS, Auteur ; Bennett LEVENTHAL, Auteur ; Kathleen MERIKANGAS, Auteur ; Michael P. MILHAM, Auteur ; Adriana DI MARTINO, Auteur . - 7 p. Langues : Anglais (eng) in Molecular Autism > 14 (2023) . - 7 p. Index. décimale : PER Périodiques Résumé : BACKGROUND: Heterogeneous mental health outcomes during the COVID-19 pandemic are documented in the general population. Such heterogeneity has not been systematically assessed in youth with autism spectrum disorder (ASD) and related neurodevelopmental disorders (NDD). To identify distinct patterns of the pandemic impact and their predictors in ASD/NDD youth, we focused on pandemic-related changes in symptoms and access to services. METHODS: Using a naturalistic observational design, we assessed parent responses on the Coronavirus Health and Impact Survey Initiative (CRISIS) Adapted For Autism and Related neurodevelopmental conditions (AFAR). Cross-sectional AFAR data were aggregated across 14 European and North American sites yielding a clinically well-characterized sample of N=1275 individuals with ASD/NDD (age=11.0?+?3.6 years; n females=277). To identify subgroups with differential outcomes, we applied hierarchical clustering across eleven variables measuring changes in symptoms and access to services. Then, random forest classification assessed the importance of socio-demographics, pre-pandemic service rates, clinical severity of ASD-associated symptoms, and COVID-19 pandemic experiences/environments in predicting the outcome subgroups. RESULTS: Clustering revealed four subgroups. One subgroup-broad symptom worsening only (20%)-included youth with worsening across a range of symptoms but with service disruptions similar to the average of the aggregate sample. The other three subgroups were, relatively, clinically stable but differed in service access: primarily modified services (23%), primarily lost services (6%), and average services/symptom changes (53%). Distinct combinations of a set of pre-pandemic services, pandemic environment (e.g., COVID-19 new cases, restrictions), experiences (e.g., COVID-19 Worries), and age predicted each outcome subgroup. LIMITATIONS: Notable limitations of the study are its cross-sectional nature and focus on the first six months of the pandemic. CONCLUSIONS: Concomitantly assessing variation in changes of symptoms and service access during the first phase of the pandemic revealed differential outcome profiles in ASD/NDD youth. Subgroups were characterized by distinct prediction patterns across a set of pre- and pandemic-related experiences/contexts. Results may inform recovery efforts and preparedness in future crises; they also underscore the critical value of international data-sharing and collaborations to address the needs of those most vulnerable in times of crisis. En ligne : http://dx.doi.org/10.1186/s13229-022-00536-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513

Gender diversity is correlated with dimensional neurodivergent traits but not categorical neurodevelopmental diagnoses in children / Evdokia ANAGNOSTOU ; Jason P. LERCH ; Margot J. TAYLOR ; Doug P. VANDERLAAN ; Peter SZATMARI ; Jennifer CROSBIE ; Robert NICOLSON ; Stelios GEORGIADIS ; Elizabeth KELLEY ; Muhammad AYUB ; Jessica BRIAN ; Meng-Chuan LAI ; Mark R. PALMERT in Journal of Child Psychology and Psychiatry, 65-9 (September 2024)  

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Inattention and hyperactive/impulsive component scores do not differentiate between autism spectrum disorder and attention-deficit/hyperactivity disorder in a clinical sample / Aneta D. KRAKOWSKI in Molecular Autism, 11 (2020)  

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Obsessive-compulsive disorder in children and youth: neurocognitive function in clinic and community samples / Russell SCHACHAR in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

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The persistence of cognitive deficits in remitted and unremitted ADHD: a case for the state-independence of response inhibition / Tara MCAULEY in Journal of Child Psychology and Psychiatry, 55-3 (March 2014)  

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Transdiagnostic Patterns of Sensory Processing in Autism and ADHD / Anahid POURTOUSI ; Connie YANG ; Zining DING ; Bobby STOJANOSKI ; Evdokia ANAGNOSTOU ; Robert NICOLSON ; Elizabeth KELLEY ; Stelios GEORGIADES ; Jennifer CROSBIE ; Russell SCHACHAR ; Muhammad AYUB ; Ryan A. STEVENSON in Journal of Autism and Developmental Disorders, 54-1 (January 2024)  

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