Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 / Sinnika Birkehøj ROHD in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1540-1551 Titre : Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 Type de document : Texte imprimé et/ou numérique Auteurs : Sinnika Birkehøj ROHD, Auteur ; Carsten HJORTHØJ, Auteur ; Jessica OHLAND, Auteur ; Maja GREGERSEN, Auteur ; Nicoline HEMAGER, Auteur ; Anne SØNDERGAARD, Auteur ; Camilla Austa CHRISTIANI, Auteur ; Katrine Soeborg SPANG, Auteur ; Ditte ELLERSGAARD, Auteur ; Birgitte Klee BURTON, Auteur ; Marianne MELAU, Auteur ; Aja GREVE, Auteur ; Ditte Lou GANTRIIS, Auteur ; Jens Richardt Møllegaard JEPSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Ole MORS, Auteur ; Merete NORDENTOFT, Auteur ; Susanne HARDER, Auteur ; Anne Amalie Elgaard THORUP, Auteur Article en page(s) : p.1540-1551 Langues : Anglais (eng) Mots-clés : caregiving and child psychopathology  children at familial high risk  level of functioning  indicators of disorganized caregiving  parental mental illness Index. décimale : PER Périodiques Résumé : This study investigates indicators of disorganized caregiving among caregivers of children who have a familial predisposition of schizophrenia spectrum psychosis (SZ) or bipolar disorder (BP), and whether indicators of disorganized caregiving are associated with the caregivers' and children?s level of functioning as well as the children?s internalizing and externalizing behavior problems. Indicators of disorganized caregiving were assessed with the Caregiving Helplessness Questionnaire (CHQ). Level of functioning was evaluated using the Children?s Global Assessment Scale and the Personal and Social Performance Scale, while dimensional psychopathology were measured with the Child Behavior Checklist. 185 caregivers belonging to a SZ combined group (i.e., SZ-I + SZ co-caregiver), 110 caregivers to a BP combined group (i.e., BP-I + BP co-caregiver), and 184 caregivers to a population-based control group provided data on CHQ. Having a history of SZ or BP or being a co-caregiver to a parent with SZ or BP was associated with higher levels of experiences of helplessness and fear. Higher scores on helplessness were associated with lower level of functioning among caregivers and children and with children having externalizing/internalizing behavior problems. These results emphasize the need for interventions addressing indicators of disorganized caregiving in families with SZ or BP. En ligne : http://dx.doi.org/10.1017/S0954579422000281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Experiences of helplessness and fear among caregivers diagnosed with severe mental illness and co-caregivers: The Danish High Risk and Resilience Study - VIA 7 [Texte imprimé et/ou numérique] / Sinnika Birkehøj ROHD, Auteur ; Carsten HJORTHØJ, Auteur ; Jessica OHLAND, Auteur ; Maja GREGERSEN, Auteur ; Nicoline HEMAGER, Auteur ; Anne SØNDERGAARD, Auteur ; Camilla Austa CHRISTIANI, Auteur ; Katrine Soeborg SPANG, Auteur ; Ditte ELLERSGAARD, Auteur ; Birgitte Klee BURTON, Auteur ; Marianne MELAU, Auteur ; Aja GREVE, Auteur ; Ditte Lou GANTRIIS, Auteur ; Jens Richardt Møllegaard JEPSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Ole MORS, Auteur ; Merete NORDENTOFT, Auteur ; Susanne HARDER, Auteur ; Anne Amalie Elgaard THORUP, Auteur . - p.1540-1551. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1540-1551 Mots-clés : caregiving and child psychopathology  children at familial high risk  level of functioning  indicators of disorganized caregiving  parental mental illness Index. décimale : PER Périodiques Résumé : This study investigates indicators of disorganized caregiving among caregivers of children who have a familial predisposition of schizophrenia spectrum psychosis (SZ) or bipolar disorder (BP), and whether indicators of disorganized caregiving are associated with the caregivers' and children?s level of functioning as well as the children?s internalizing and externalizing behavior problems. Indicators of disorganized caregiving were assessed with the Caregiving Helplessness Questionnaire (CHQ). Level of functioning was evaluated using the Children?s Global Assessment Scale and the Personal and Social Performance Scale, while dimensional psychopathology were measured with the Child Behavior Checklist. 185 caregivers belonging to a SZ combined group (i.e., SZ-I + SZ co-caregiver), 110 caregivers to a BP combined group (i.e., BP-I + BP co-caregiver), and 184 caregivers to a population-based control group provided data on CHQ. Having a history of SZ or BP or being a co-caregiver to a parent with SZ or BP was associated with higher levels of experiences of helplessness and fear. Higher scores on helplessness were associated with lower level of functioning among caregivers and children and with children having externalizing/internalizing behavior problems. These results emphasize the need for interventions addressing indicators of disorganized caregiving in families with SZ or BP. En ligne : http://dx.doi.org/10.1017/S0954579422000281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis / Birgitte K. BURTON in Journal of Child Psychology and Psychiatry, 57-4 (April 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.446-456 Titre : Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Birgitte K. BURTON, Auteur ; Carsten HJORTHØJ, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Anne THORUP, Auteur ; Merete NORDENTOFT, Auteur ; Kerstin J. PLESSEN, Auteur Article en page(s) : p.446-456 Langues : Anglais (eng) Mots-clés : Motor function  endophenotype  early detection  first-degree relatives  schizophrenia Index. décimale : PER Périodiques Résumé : Background Early detection of schizophrenia risk is a critical goal in the field. Endophenotypes in children to relatives of affected individuals may contribute to this early detection. One of the lowest cost and longest theorized domains is motor development in children. Methods A meta-analysis was conducted comparing individuals ?21 years old with affected first-degree relatives (FDR) with (1) individuals from unaffected families (controls), or (2) individuals with FDR having other psychiatric disorders. Studies were classified by motor outcome and separate meta-analyses were performed across six correlated domains, with available N varying by domain. Results Inclusion criteria were met by k = 23 independent studies with a total N = 18,582, and N across domains varying from 167 to 8619. The youth from affected families had delays in gross and fine motor development in infancy (k = 3, n = 167, Hedges'g = 0.644, confidence intervals (CI) = [0.328, 0.960], p < .001), walking milestones (k = 3, n = 608, g = 0.444, CI = [0.108, 0.780], p = .01), coordination (k = 8, n = 8619, g = 0.625, CI = [0.453, 0.797], p < .0001), and had more abnormal movements such as involuntary movements (k = 6, n = 8365, g = 0.291, CI = [0.041, 0.542], p = .02) compared with controls. However, not all effects survived correction for publication bias. Effects for neurological soft signs were small and not reliably different from zero (k = 4, n = 548, g = 0.238, CI = [?0.106, 0.583], p = .18). When comparing the FDR group to youth from families with other psychiatric disorders, the FDR group was distinguished by poorer gross and fine motor skills (k = 2, n = 275, g = 0.847, CI = [0.393, 1.300], p < .001). Conclusions Motor deficits during development likely represent an endophenotype for schizophrenia, although its specificity is limited in relation to other serious mental disorders. It holds promise as a low cost domain for early risk detection, although it will have to be combined with other indicators to achieve clinically usable prediction accuracy. Impaired coordination was the most robust result with a moderate effect size and lack of heterogeneity and publication bias. En ligne : http://dx.doi.org/10.1111/jcpp.12479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285 [article] Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis [Texte imprimé et/ou numérique] / Birgitte K. BURTON, Auteur ; Carsten HJORTHØJ, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Anne THORUP, Auteur ; Merete NORDENTOFT, Auteur ; Kerstin J. PLESSEN, Auteur . - p.446-456. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.446-456 Mots-clés : Motor function  endophenotype  early detection  first-degree relatives  schizophrenia Index. décimale : PER Périodiques Résumé : Background Early detection of schizophrenia risk is a critical goal in the field. Endophenotypes in children to relatives of affected individuals may contribute to this early detection. One of the lowest cost and longest theorized domains is motor development in children. Methods A meta-analysis was conducted comparing individuals ?21 years old with affected first-degree relatives (FDR) with (1) individuals from unaffected families (controls), or (2) individuals with FDR having other psychiatric disorders. Studies were classified by motor outcome and separate meta-analyses were performed across six correlated domains, with available N varying by domain. Results Inclusion criteria were met by k = 23 independent studies with a total N = 18,582, and N across domains varying from 167 to 8619. The youth from affected families had delays in gross and fine motor development in infancy (k = 3, n = 167, Hedges'g = 0.644, confidence intervals (CI) = [0.328, 0.960], p < .001), walking milestones (k = 3, n = 608, g = 0.444, CI = [0.108, 0.780], p = .01), coordination (k = 8, n = 8619, g = 0.625, CI = [0.453, 0.797], p < .0001), and had more abnormal movements such as involuntary movements (k = 6, n = 8365, g = 0.291, CI = [0.041, 0.542], p = .02) compared with controls. However, not all effects survived correction for publication bias. Effects for neurological soft signs were small and not reliably different from zero (k = 4, n = 548, g = 0.238, CI = [?0.106, 0.583], p = .18). When comparing the FDR group to youth from families with other psychiatric disorders, the FDR group was distinguished by poorer gross and fine motor skills (k = 2, n = 275, g = 0.847, CI = [0.393, 1.300], p < .001). Conclusions Motor deficits during development likely represent an endophenotype for schizophrenia, although its specificity is limited in relation to other serious mental disorders. It holds promise as a low cost domain for early risk detection, although it will have to be combined with other indicators to achieve clinically usable prediction accuracy. Impaired coordination was the most robust result with a moderate effect size and lack of heterogeneity and publication bias. En ligne : http://dx.doi.org/10.1111/jcpp.12479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285

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