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Auteur Sheila GAHAGAN |
Documents disponibles écrits par cet auteur (3)



Early-life adversity is associated with poor iron status in infancy / Patricia EAST ; Estela BLANCO ; Jenalee R. DOOM ; Raquel A. BURROWS ; Paulina CORREA-BURROWS ; Betsy LOZOFF ; Sheila GAHAGAN in Development and Psychopathology, 35-4 (October 2023)
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[article]
Titre : Early-life adversity is associated with poor iron status in infancy Type de document : Texte imprimé et/ou numérique Auteurs : Patricia EAST, Auteur ; Estela BLANCO, Auteur ; Jenalee R. DOOM, Auteur ; Raquel A. BURROWS, Auteur ; Paulina CORREA-BURROWS, Auteur ; Betsy LOZOFF, Auteur ; Sheila GAHAGAN, Auteur Article en page(s) : p.1856-1867 Langues : Anglais (eng) Mots-clés : early-life adversity infancy iron deficiency nutrition stress Index. décimale : PER Périodiques Résumé : Exposure to early-life adversity (ELA) and iron deficiency early in life are known risk factors for suboptimal brain and socioemotional development. Iron deficiency may arise from and co-occur with ELA, which could negatively affect development. In the present study, we investigated whether ELA is associated with iron deficiency in infants receiving no iron supplementation. This study is a secondary analysis of extant data collected in the 1990s; participants were healthy infants from working-class communities in Santiago, Chile (N = 534, 45.5% female). We measured stressful life events, maternal depression, and low home support for child development during infancy and assessed iron status when the infant was 12 months old. Slightly more than half of the infants were iron-deficient (51%), and 25.8% were iron-deficient anemic at 12 months. Results indicated that ELA was associated with lower iron levels and iron deficiency at 12 months. The findings are consistent with animal and human prenatal models of stress and iron status and provide evidence of the association between postnatal ELA and iron status in humans. The findings also highlight a nutritional pathway by which ELA may impact development and present a nutritionally-focused avenue for future research on ELA and psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579422000517 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515
in Development and Psychopathology > 35-4 (October 2023) . - p.1856-1867[article] Early-life adversity is associated with poor iron status in infancy [Texte imprimé et/ou numérique] / Patricia EAST, Auteur ; Estela BLANCO, Auteur ; Jenalee R. DOOM, Auteur ; Raquel A. BURROWS, Auteur ; Paulina CORREA-BURROWS, Auteur ; Betsy LOZOFF, Auteur ; Sheila GAHAGAN, Auteur . - p.1856-1867.
Langues : Anglais (eng)
in Development and Psychopathology > 35-4 (October 2023) . - p.1856-1867
Mots-clés : early-life adversity infancy iron deficiency nutrition stress Index. décimale : PER Périodiques Résumé : Exposure to early-life adversity (ELA) and iron deficiency early in life are known risk factors for suboptimal brain and socioemotional development. Iron deficiency may arise from and co-occur with ELA, which could negatively affect development. In the present study, we investigated whether ELA is associated with iron deficiency in infants receiving no iron supplementation. This study is a secondary analysis of extant data collected in the 1990s; participants were healthy infants from working-class communities in Santiago, Chile (N = 534, 45.5% female). We measured stressful life events, maternal depression, and low home support for child development during infancy and assessed iron status when the infant was 12 months old. Slightly more than half of the infants were iron-deficient (51%), and 25.8% were iron-deficient anemic at 12 months. Results indicated that ELA was associated with lower iron levels and iron deficiency at 12 months. The findings are consistent with animal and human prenatal models of stress and iron status and provide evidence of the association between postnatal ELA and iron status in humans. The findings also highlight a nutritional pathway by which ELA may impact development and present a nutritionally-focused avenue for future research on ELA and psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579422000517 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515 Re-examining the core features of autism: a comparison of autism spectrum disorder and fetal alcohol spectrum disorder / Somer L. BISHOP in Journal of Child Psychology and Psychiatry, 48-11 (November 2007)
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Titre : Re-examining the core features of autism: a comparison of autism spectrum disorder and fetal alcohol spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Somer L. BISHOP, Auteur ; Catherine LORD, Auteur ; Sheila GAHAGAN, Auteur Année de publication : 2007 Article en page(s) : p.1111–1121 Langues : Anglais (eng) Mots-clés : Autism-Diagnostic-Observation-Schedule-(ADOS) Autism-Diagnostic-Interview-Revised-(ADI-R) social-deficits diagnosis autistic-disorder pervasive-developmental-disorder diagnosis fetal-alcohol-syndrome social-behavior symptomatology Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and fetal alcohol spectrum disorder (FASD) are both characterized by social difficulties, but overall clinical descriptions of the two disorders are different.
Method: Twenty-nine children with autism and 33 children with pervasive developmental disorder-not otherwise specified (PDD-NOS) were compared to 29 children with FASD of equivalent age and full-scale IQ. To isolate social deficits that are most unique to ASD, all participants were administered the Autism Diagnostic Observation Schedule (ADOS). Parents of the children completed the Autism Diagnostic Interview-Revised (ADI-R).
Results: Difficulties in initiating social interaction, sharing affect, and using nonverbal communication were common in children with ASD but rare in children with FASD. Socially inappropriate behaviors and difficulty with peers were common in both groups.
Conclusions: These findings suggest that whereas propensity for social interaction appears to be a differentiating factor between children with ASD and those with non-spectrum disorders, impaired quality of social interaction may be less diagnostically discriminative.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01782.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297
in Journal of Child Psychology and Psychiatry > 48-11 (November 2007) . - p.1111–1121[article] Re-examining the core features of autism: a comparison of autism spectrum disorder and fetal alcohol spectrum disorder [Texte imprimé et/ou numérique] / Somer L. BISHOP, Auteur ; Catherine LORD, Auteur ; Sheila GAHAGAN, Auteur . - 2007 . - p.1111–1121.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 48-11 (November 2007) . - p.1111–1121
Mots-clés : Autism-Diagnostic-Observation-Schedule-(ADOS) Autism-Diagnostic-Interview-Revised-(ADI-R) social-deficits diagnosis autistic-disorder pervasive-developmental-disorder diagnosis fetal-alcohol-syndrome social-behavior symptomatology Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and fetal alcohol spectrum disorder (FASD) are both characterized by social difficulties, but overall clinical descriptions of the two disorders are different.
Method: Twenty-nine children with autism and 33 children with pervasive developmental disorder-not otherwise specified (PDD-NOS) were compared to 29 children with FASD of equivalent age and full-scale IQ. To isolate social deficits that are most unique to ASD, all participants were administered the Autism Diagnostic Observation Schedule (ADOS). Parents of the children completed the Autism Diagnostic Interview-Revised (ADI-R).
Results: Difficulties in initiating social interaction, sharing affect, and using nonverbal communication were common in children with ASD but rare in children with FASD. Socially inappropriate behaviors and difficulty with peers were common in both groups.
Conclusions: These findings suggest that whereas propensity for social interaction appears to be a differentiating factor between children with ASD and those with non-spectrum disorders, impaired quality of social interaction may be less diagnostically discriminative.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01782.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 Sensitive periods for psychosocial risk in childhood and adolescence and cardiometabolic outcomes in young adulthood / Jenalee R. DOOM in Development and Psychopathology, 32-5 (December 2020)
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Titre : Sensitive periods for psychosocial risk in childhood and adolescence and cardiometabolic outcomes in young adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Jenalee R. DOOM, Auteur ; Kenia M. RIVERA, Auteur ; Estela BLANCO, Auteur ; Raquel BURROWS, Auteur ; Paulina CORREA-BURROWS, Auteur ; Patricia L. EAST, Auteur ; Betsy LOZOFF, Auteur ; Sheila GAHAGAN, Auteur Article en page(s) : p.1864-1875 Langues : Anglais (eng) Mots-clés : Adolescent Adult Body Mass Index *Cardiovascular Diseases Child Chile Female Humans Infant Longitudinal Studies Male Risk Factors Young Adult *cardiometabolic risk *infancy *metabolic syndrome *psychosocial risk *young adulthood Index. décimale : PER Périodiques Résumé : Greater psychosocial risk in childhood and adolescence predicts poorer cardiometabolic outcomes in adulthood. We assessed whether the timing of psychosocial risk from infancy through adolescence predicts cardiometabolic outcomes in young adulthood. Young adults and their mothers participated in a longitudinal study beginning in infancy in Santiago, Chile (N = 1040). At infancy, 5 years, 10 years, and adolescence, mothers reported on depressive symptoms, stressful experiences, support for child development in the home, father absence, parental education, and socioeconomic status (SES) to create a psychosocial risk composite at each time point. Young adults (52.1% female; 21-27 years) provided fasting serum samples and participated in anthropometric and blood pressure (BP) assessments, including a dual-energy X-ray absorptiometry (DXA) scan for measuring body fat. Greater infant psychosocial risk was associated with a greater young adult metabolic syndrome score (? = 0.07, 95% confidence intervals (CI): 0.01 to 0.13, p = 0.02), a higher body mass index and waist circumference composite (? = 0.08, 95% CI: 0.03 to 0.13, p = 0.002), and a higher body fat (DXA) composite (? = 0.07, 95% CI: 0.01 to 0.12, p = 0.02). No psychosocial risk measure from any time point was associated with BP. Infant psychosocial risk predicted cardiometabolic outcomes in young adulthood better than psychosocial risk at 5 years, 10 years, or adolescence, mean of psychosocial risk from infancy through adolescence, and maximum of psychosocial risk at any one time. Consistent with the Developmental Origins of Health and Disease model, findings suggest that infancy is a sensitive period for psychosocial risk leading to poorer cardiometabolic outcomes in young adulthood. En ligne : http://dx.doi.org/10.1017/s0954579420001248 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437
in Development and Psychopathology > 32-5 (December 2020) . - p.1864-1875[article] Sensitive periods for psychosocial risk in childhood and adolescence and cardiometabolic outcomes in young adulthood [Texte imprimé et/ou numérique] / Jenalee R. DOOM, Auteur ; Kenia M. RIVERA, Auteur ; Estela BLANCO, Auteur ; Raquel BURROWS, Auteur ; Paulina CORREA-BURROWS, Auteur ; Patricia L. EAST, Auteur ; Betsy LOZOFF, Auteur ; Sheila GAHAGAN, Auteur . - p.1864-1875.
Langues : Anglais (eng)
in Development and Psychopathology > 32-5 (December 2020) . - p.1864-1875
Mots-clés : Adolescent Adult Body Mass Index *Cardiovascular Diseases Child Chile Female Humans Infant Longitudinal Studies Male Risk Factors Young Adult *cardiometabolic risk *infancy *metabolic syndrome *psychosocial risk *young adulthood Index. décimale : PER Périodiques Résumé : Greater psychosocial risk in childhood and adolescence predicts poorer cardiometabolic outcomes in adulthood. We assessed whether the timing of psychosocial risk from infancy through adolescence predicts cardiometabolic outcomes in young adulthood. Young adults and their mothers participated in a longitudinal study beginning in infancy in Santiago, Chile (N = 1040). At infancy, 5 years, 10 years, and adolescence, mothers reported on depressive symptoms, stressful experiences, support for child development in the home, father absence, parental education, and socioeconomic status (SES) to create a psychosocial risk composite at each time point. Young adults (52.1% female; 21-27 years) provided fasting serum samples and participated in anthropometric and blood pressure (BP) assessments, including a dual-energy X-ray absorptiometry (DXA) scan for measuring body fat. Greater infant psychosocial risk was associated with a greater young adult metabolic syndrome score (? = 0.07, 95% confidence intervals (CI): 0.01 to 0.13, p = 0.02), a higher body mass index and waist circumference composite (? = 0.08, 95% CI: 0.03 to 0.13, p = 0.002), and a higher body fat (DXA) composite (? = 0.07, 95% CI: 0.01 to 0.12, p = 0.02). No psychosocial risk measure from any time point was associated with BP. Infant psychosocial risk predicted cardiometabolic outcomes in young adulthood better than psychosocial risk at 5 years, 10 years, or adolescence, mean of psychosocial risk from infancy through adolescence, and maximum of psychosocial risk at any one time. Consistent with the Developmental Origins of Health and Disease model, findings suggest that infancy is a sensitive period for psychosocial risk leading to poorer cardiometabolic outcomes in young adulthood. En ligne : http://dx.doi.org/10.1017/s0954579420001248 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437