[article]
| Titre : |
Middle-childhood executive functioning mediates associations between early-childhood autism symptoms and adolescent mental health, academic and functional outcomes in autistic children |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Stephanie H. AMEIS, Auteur ; John D. HALTIGAN, Auteur ; Rachael E. LYON, Auteur ; Amanda SAWYER, Auteur ; Pat MIRENDA, Auteur ; Connor M. KERNS, Auteur ; Isabel M. SMITH, Auteur ; Tracy VAILLANCOURT, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Teresa BENNETT, Auteur ; Eric DUKU, Auteur ; Mayada ELSABBAGH, Auteur ; Stelios GEORGIADES, Auteur ; Wendy J. UNGAR, Auteur ; Anat ZAIDMAN-ZAIT, Auteur ; Meng-Chuan LAI, Auteur ; Peter SZATMARI, Auteur |
| Article en page(s) : |
p.553-562 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Adolescent Autism Spectrum Disorder Autistic Disorder/complications Child Executive Function Humans Mental Health Parents academic performance adaptive functioning internalizing/externalizing behavior longitudinal studies |
| Index. décimale : |
PER Périodiques |
| Résumé : |
BACKGROUND: Executive functioning (EF) varies in children with autism spectrum disorder (ASD) and is associated with clinical symptoms, academic, and adaptive functioning. Here, we examined whether middle-childhood EF mediates associations between early-childhood autism symptoms and adolescent outcomes in children with ASD. METHODS: The Pathways in ASD Cohort comprising children recruited at the time of ASD diagnosis (at 2-4?years-of-age) and followed prospectively across eight subsequent timepoints over ~10?years was used. A subset of Pathways participants (n=250) with Behavior Rating Inventory of Executive Function (BRIEF)-Parent Form data from at least one timepoint when participants were school-aged was analyzed. A mediation framework was used to examine whether BRIEF-measured EF across age 7-10?years (middle-childhood) mediated associations between early-childhood autism symptoms (measured using the parent-report Social Responsiveness Scale across age 2-6?years) and clinical, academic, and functional outcomes, indexed at age >10-11.8?years (early-adolescence) using the Child Behavior Checklist (CBCL)-Internalizing and Externalizing Scales, Academic Performance from the Teacher's Report Form, and Vineland Adaptive Behavior Scales. Models were rerun substituting clinician-rated and teacher-rated measures, where possible. RESULTS: Mediation models indicated a significant indirect effect of middle-childhood EF on associations between early-childhood autism symptoms and externalizing behavior, academic performance, or adaptive functioning in early adolescence; kappa squared (?(2) ) effect sizes ranged from large to small. Model findings were stable across raters. Middle-childhood EF did not mediate associations between early-childhood autism symptoms and adolescent internalizing behavior. CONCLUSIONS: Among children with an ASD diagnosis, middle-childhood EF may be one pathway through which early-childhood autism symptoms influence a variety of outcomes in early-adolescence. An experimental study targeting middle-childhood EF to improve adolescent academic, emotional/behavioral, and adaptive functioning is needed to evaluate the clinical meaningfulness of these findings. |
| En ligne : |
http://dx.doi.org/10.1111/jcpp.13493 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 |
in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.553-562
[article] Middle-childhood executive functioning mediates associations between early-childhood autism symptoms and adolescent mental health, academic and functional outcomes in autistic children [Texte imprimé et/ou numérique] / Stephanie H. AMEIS, Auteur ; John D. HALTIGAN, Auteur ; Rachael E. LYON, Auteur ; Amanda SAWYER, Auteur ; Pat MIRENDA, Auteur ; Connor M. KERNS, Auteur ; Isabel M. SMITH, Auteur ; Tracy VAILLANCOURT, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Teresa BENNETT, Auteur ; Eric DUKU, Auteur ; Mayada ELSABBAGH, Auteur ; Stelios GEORGIADES, Auteur ; Wendy J. UNGAR, Auteur ; Anat ZAIDMAN-ZAIT, Auteur ; Meng-Chuan LAI, Auteur ; Peter SZATMARI, Auteur . - p.553-562. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.553-562
| Mots-clés : |
Adolescent Autism Spectrum Disorder Autistic Disorder/complications Child Executive Function Humans Mental Health Parents academic performance adaptive functioning internalizing/externalizing behavior longitudinal studies |
| Index. décimale : |
PER Périodiques |
| Résumé : |
BACKGROUND: Executive functioning (EF) varies in children with autism spectrum disorder (ASD) and is associated with clinical symptoms, academic, and adaptive functioning. Here, we examined whether middle-childhood EF mediates associations between early-childhood autism symptoms and adolescent outcomes in children with ASD. METHODS: The Pathways in ASD Cohort comprising children recruited at the time of ASD diagnosis (at 2-4?years-of-age) and followed prospectively across eight subsequent timepoints over ~10?years was used. A subset of Pathways participants (n=250) with Behavior Rating Inventory of Executive Function (BRIEF)-Parent Form data from at least one timepoint when participants were school-aged was analyzed. A mediation framework was used to examine whether BRIEF-measured EF across age 7-10?years (middle-childhood) mediated associations between early-childhood autism symptoms (measured using the parent-report Social Responsiveness Scale across age 2-6?years) and clinical, academic, and functional outcomes, indexed at age >10-11.8?years (early-adolescence) using the Child Behavior Checklist (CBCL)-Internalizing and Externalizing Scales, Academic Performance from the Teacher's Report Form, and Vineland Adaptive Behavior Scales. Models were rerun substituting clinician-rated and teacher-rated measures, where possible. RESULTS: Mediation models indicated a significant indirect effect of middle-childhood EF on associations between early-childhood autism symptoms and externalizing behavior, academic performance, or adaptive functioning in early adolescence; kappa squared (?(2) ) effect sizes ranged from large to small. Model findings were stable across raters. Middle-childhood EF did not mediate associations between early-childhood autism symptoms and adolescent internalizing behavior. CONCLUSIONS: Among children with an ASD diagnosis, middle-childhood EF may be one pathway through which early-childhood autism symptoms influence a variety of outcomes in early-adolescence. An experimental study targeting middle-childhood EF to improve adolescent academic, emotional/behavioral, and adaptive functioning is needed to evaluate the clinical meaningfulness of these findings. |
| En ligne : |
http://dx.doi.org/10.1111/jcpp.13493 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 |
|
Middle-childhood executive functioning mediates associations between early-childhood autism symptoms and adolescent mental health, academic and functional outcomes in autistic children in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)
