Actual and perceived speedy diagnoses are associated with mothers' unresolved reactions to a diagnosis of autism spectrum disorder for a child / P. REED in Autism, 23-7 (October 2019)  

Public ISBD [article]  inAutism > 23-7 (October 2019) . - p.1843-1852 Titre : Actual and perceived speedy diagnoses are associated with mothers' unresolved reactions to a diagnosis of autism spectrum disorder for a child Type de document : Texte imprimé et/ou numérique Auteurs : P. REED, Auteur ; A. GILES, Auteur ; S. WHITE, Auteur ; L. A. OSBORNE, Auteur Article en page(s) : p.1843-1852 Langues : Anglais (eng) Mots-clés : autism diagnosis  autism spectrum disorder  parent mental health  professional interpersonal skills  reaction to diagnosis  speed of diagnosis Index. décimale : PER Périodiques Résumé : Reaction to a child's diagnosis can strongly affect the parent, but little is known about the aspects of the diagnostic process associated with such reactions. The pre-diagnostic levels of anxiety, depression, and parenting stress of 67 volunteer mothers of children subsequently diagnosed with autism spectrum disorder were assessed, along with the children's functioning. The speed and number of professionals involved in the diagnosis were recorded, and mothers completed a post-diagnosis assessment of their perceptions of the process. Longer actual and perceived diagnosis speeds predicted resolved reactions to diagnosis. Mothers' psychological states pre-diagnosis did not predict reactions to diagnosis. Providing a measured diagnostic process, and strong relationship with mothers, rather than aiming for speed alone, may well be more productive for the parent and child. En ligne : http://dx.doi.org/10.1177/1362361319833676 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Actual and perceived speedy diagnoses are associated with mothers' unresolved reactions to a diagnosis of autism spectrum disorder for a child [Texte imprimé et/ou numérique] / P. REED, Auteur ; A. GILES, Auteur ; S. WHITE, Auteur ; L. A. OSBORNE, Auteur . - p.1843-1852. Langues : Anglais (eng) in Autism > 23-7 (October 2019) . - p.1843-1852 Mots-clés : autism diagnosis  autism spectrum disorder  parent mental health  professional interpersonal skills  reaction to diagnosis  speed of diagnosis Index. décimale : PER Périodiques Résumé : Reaction to a child's diagnosis can strongly affect the parent, but little is known about the aspects of the diagnostic process associated with such reactions. The pre-diagnostic levels of anxiety, depression, and parenting stress of 67 volunteer mothers of children subsequently diagnosed with autism spectrum disorder were assessed, along with the children's functioning. The speed and number of professionals involved in the diagnosis were recorded, and mothers completed a post-diagnosis assessment of their perceptions of the process. Longer actual and perceived diagnosis speeds predicted resolved reactions to diagnosis. Mothers' psychological states pre-diagnosis did not predict reactions to diagnosis. Providing a measured diagnostic process, and strong relationship with mothers, rather than aiming for speed alone, may well be more productive for the parent and child. En ligne : http://dx.doi.org/10.1177/1362361319833676 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

Do cognitive deficits persist into adolescence in autism? / Cathriona CANTIO in Autism Research, 11-9 (September 2018)  

Public ISBD [article]  inAutism Research > 11-9 (September 2018) . - p.1229-1238 Titre : Do cognitive deficits persist into adolescence in autism? Type de document : Texte imprimé et/ou numérique Auteurs : Cathriona CANTIO, Auteur ; S. WHITE, Auteur ; G. F. MADSEN, Auteur ; Niels BILENBERG, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur Article en page(s) : p.1229-1238 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  adolescent development  cognition  executive function  theory of mind Index. décimale : PER Périodiques Résumé : SEVERAL THEORIES HAVE ATTEMPTED TO CHARACTERISE AUTISM SPECTRUM DISORDERS (ASDS) AT THE COGNITIVE LEVEL, MOST NOTABLY: THEORY OF MIND (TOM), EXECUTIVE FUNCTION (EF), AND A LOCAL PROCESSING BIAS (LB). THE AIM OF THIS STUDY WAS TO INVESTIGATE HOW THESE COGNITIVE FUNCTIONS DEVELOP OVER TIME: The three cognitive domains (ToM, EF, and LB) were examined in a group of high-functioning children (age: 8-12, mean 10.85; IQ: 78-139, mean 105.48) with ASD and a matched group of children with neurotypical development (NTD) (IQ: 75-145, mean: 109.47), and several tasks were used within each domain to ensure the validity of the cognitive measures. Approximately 3 years later (mean age: 14.34), all children and their families were invited to participate in the follow-up (ASD, N = 21; NTD, N = 30). While the understanding of other's minds does improve from childhood to adolescence, ToM impairment persists in adolescents with ASD relative to their peers. Likewise, a development in EF was observed in the ASD group, while no significant improvement was seen in the NTD group, leading the ASD group to catch up in this domain. We did not detect any group differences at any time point regarding local bias processing (LB). Individual patterns of development were seen, but remarkably, ToM deficits were present in every child with ASD in whom we could detect any cognitive impairment at baseline, and a similar pattern was found at follow-up. These findings indicate that ToM is a persistent cognitive deficit in ASD. Autism Res 2018, 11: 1229-1238. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This was the first study to investigate the development of three well-known cognitive functions into adolescence: While the understanding of other's minds improves from childhood to adolescence, adolescents with ASD are still impaired relative to their peers. The EFs, however, seem to improve to a neurotypical level in ASD as children enter adolescence, while local processing bias seems to differentiate the groups only in early childhood. En ligne : http://dx.doi.org/10.1002/aur.1976 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Do cognitive deficits persist into adolescence in autism? [Texte imprimé et/ou numérique] / Cathriona CANTIO, Auteur ; S. WHITE, Auteur ; G. F. MADSEN, Auteur ; Niels BILENBERG, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur . - p.1229-1238. Langues : Anglais (eng) in Autism Research > 11-9 (September 2018) . - p.1229-1238 Mots-clés : Autism spectrum disorders  adolescent development  cognition  executive function  theory of mind Index. décimale : PER Périodiques Résumé : SEVERAL THEORIES HAVE ATTEMPTED TO CHARACTERISE AUTISM SPECTRUM DISORDERS (ASDS) AT THE COGNITIVE LEVEL, MOST NOTABLY: THEORY OF MIND (TOM), EXECUTIVE FUNCTION (EF), AND A LOCAL PROCESSING BIAS (LB). THE AIM OF THIS STUDY WAS TO INVESTIGATE HOW THESE COGNITIVE FUNCTIONS DEVELOP OVER TIME: The three cognitive domains (ToM, EF, and LB) were examined in a group of high-functioning children (age: 8-12, mean 10.85; IQ: 78-139, mean 105.48) with ASD and a matched group of children with neurotypical development (NTD) (IQ: 75-145, mean: 109.47), and several tasks were used within each domain to ensure the validity of the cognitive measures. Approximately 3 years later (mean age: 14.34), all children and their families were invited to participate in the follow-up (ASD, N = 21; NTD, N = 30). While the understanding of other's minds does improve from childhood to adolescence, ToM impairment persists in adolescents with ASD relative to their peers. Likewise, a development in EF was observed in the ASD group, while no significant improvement was seen in the NTD group, leading the ASD group to catch up in this domain. We did not detect any group differences at any time point regarding local bias processing (LB). Individual patterns of development were seen, but remarkably, ToM deficits were present in every child with ASD in whom we could detect any cognitive impairment at baseline, and a similar pattern was found at follow-up. These findings indicate that ToM is a persistent cognitive deficit in ASD. Autism Res 2018, 11: 1229-1238. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This was the first study to investigate the development of three well-known cognitive functions into adolescence: While the understanding of other's minds improves from childhood to adolescence, adolescents with ASD are still impaired relative to their peers. The EFs, however, seem to improve to a neurotypical level in ASD as children enter adolescence, while local processing bias seems to differentiate the groups only in early childhood. En ligne : http://dx.doi.org/10.1002/aur.1976 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

A prospective study of fetal head growth, autistic traits and autism spectrum disorder / Laura M. E. BLANKEN in Autism Research, 11-4 (April 2018)  

Public ISBD [article]  inAutism Research > 11-4 (April 2018) . - p.602-612 Titre : A prospective study of fetal head growth, autistic traits and autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Laura M. E. BLANKEN, Auteur ; A. DASS, Auteur ; Gail A. ALVARES, Auteur ; J. VAN DER ENDE, Auteur ; Nikita K. SCHOEMAKER, Auteur ; H. EL MARROUN, Auteur ; M. HICKEY, Auteur ; C. PENNELL, Auteur ; S. WHITE, Auteur ; M. T. MAYBERY, Auteur ; Cheryl DISSANAYAKE, Auteur ; Vincent W.V. JADDOE, Auteur ; F. C. VERHULST, Auteur ; H. TIEMEIER, Auteur ; W. MCINTOSH, Auteur ; T. WHITE, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.602-612 Langues : Anglais (eng) Mots-clés : brain growth  head circumference  pregnancy  prenatal  ultrasound Index. décimale : PER Périodiques Résumé : Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population-based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism-Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population-based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602-612. (c) 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. LAY SUMMARY: It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. En ligne : http://dx.doi.org/10.1002/aur.1921 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358 [article] A prospective study of fetal head growth, autistic traits and autism spectrum disorder [Texte imprimé et/ou numérique] / Laura M. E. BLANKEN, Auteur ; A. DASS, Auteur ; Gail A. ALVARES, Auteur ; J. VAN DER ENDE, Auteur ; Nikita K. SCHOEMAKER, Auteur ; H. EL MARROUN, Auteur ; M. HICKEY, Auteur ; C. PENNELL, Auteur ; S. WHITE, Auteur ; M. T. MAYBERY, Auteur ; Cheryl DISSANAYAKE, Auteur ; Vincent W.V. JADDOE, Auteur ; F. C. VERHULST, Auteur ; H. TIEMEIER, Auteur ; W. MCINTOSH, Auteur ; T. WHITE, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.602-612. Langues : Anglais (eng) in Autism Research > 11-4 (April 2018) . - p.602-612 Mots-clés : brain growth  head circumference  pregnancy  prenatal  ultrasound Index. décimale : PER Périodiques Résumé : Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population-based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism-Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population-based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602-612. (c) 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. LAY SUMMARY: It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. En ligne : http://dx.doi.org/10.1002/aur.1921 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358

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