Correction to: High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi?Center, Cross?Sectional, Case-Control Study / MÖ KÜTÜK in Journal of Autism and Developmental Disorders, 51-11 (November 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4100 Titre : Correction to: High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi?Center, Cross?Sectional, Case-Control Study Type de document : Texte imprimé et/ou numérique Auteurs : MÖ KÜTÜK, Auteur ; A. E. TUFAN, Auteur ; F. KILIÇASLAN, Auteur ; G. GÜLER, Auteur ; F. ÇELIK, Auteur ; E. ALTINTA?, Auteur ; C. GOKCEN, Auteur ; M. KARADA?, Auteur ; Ç YEKTA?, Auteur ; T. MUTLUER, Auteur ; H. KANDEMIR, Auteur ; A. BÜBER, Auteur ; Z. TOPAL, Auteur ; U. ACIKBAS, Auteur ; A. GIRAY, Auteur ; Ö KÜTÜK, Auteur Article en page(s) : p.4100 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-021-04914-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] Correction to: High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi?Center, Cross?Sectional, Case-Control Study [Texte imprimé et/ou numérique] / MÖ KÜTÜK, Auteur ; A. E. TUFAN, Auteur ; F. KILIÇASLAN, Auteur ; G. GÜLER, Auteur ; F. ÇELIK, Auteur ; E. ALTINTA?, Auteur ; C. GOKCEN, Auteur ; M. KARADA?, Auteur ; Ç YEKTA?, Auteur ; T. MUTLUER, Auteur ; H. KANDEMIR, Auteur ; A. BÜBER, Auteur ; Z. TOPAL, Auteur ; U. ACIKBAS, Auteur ; A. GIRAY, Auteur ; Ö KÜTÜK, Auteur . - p.4100. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4100 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-021-04914-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen-Adenosine Diphosphate and Collagen-Epinephrine Closure Times / N. COBAN in Autism Research, 12-7 (July 2019)  

Public ISBD [article]  inAutism Research > 12-7 (July 2019) . - p.1069-1076 Titre : Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen-Adenosine Diphosphate and Collagen-Epinephrine Closure Times Type de document : Texte imprimé et/ou numérique Auteurs : N. COBAN, Auteur ; C. GOKCEN, Auteur ; S. AKBAYRAM, Auteur ; B. CALISGAN, Auteur Année de publication : 2019 Article en page(s) : p.1069-1076 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  blood platelets  child psychiatry  platelet function tests  serotonin Index. décimale : PER Périodiques Résumé : Changes related to the serotonin system play a key role in the etiology of autism spectrum disorder (ASD). Although we know that platelets are associated with the serotonin system, their relation to ASD has not yet been elucidated. In this study, we aim to investigate platelet parameters in children with ASD. Forty patients with ASD according to Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) and 30 healthy controls were included in the study. A complete blood count was done to measure parameters relating to platelet morphology. Moreover, prothrombin time (PT) and activated partial thromboplastin time (aPTT) were evaluated. Lastly, platelet functions were assessed with a platelet functions analyzer 100 (PFA-100) device by measuring collagen-ADP and collagen-epinephrine (EPI) closure times. There was not a significant difference between the groups in terms of platelet count, mean platelet volume (MPV), platelet distribution width, plateletcrit, PT, or aPTT parameters for ASD patients when compared to the control group (P > 0.05). However, MPV in severe ASD, as quantified by the Childhood Autism Rating Scale, was found to be significantly lower when compared to mild to moderate ASD (P = 0.047). Moreover, in terms of platelet functions, the elongation in collagen-ADP and collagen-EPI closure times were significantly higher for the ASD group (P = 0.044). These results may suggest an impairment in platelet functions rather than in platelet morphology for children with ASD. Considering these results, further investigation of thrombocyte functions in the ASD may lead to a better understanding of the pathogenesis of ASD and to the development of our limited knowledge of this disorder. Autism Res 2019, 12: 1069-1076. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Serotonin is a chemical that is found in brain as wells as in blood cells that function in blood clotting in the human body. There are problems related to serotonin in brains of people who have autism. Thus, blood clotting cells may also be affected in people who have autism. In this study, we compare blood clotting functions of children with autism with that of healthy controls. En ligne : http://dx.doi.org/10.1002/aur.2122 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Evaluation of Platelet Parameters in Children with Autism Spectrum Disorder: Elongated Collagen-Adenosine Diphosphate and Collagen-Epinephrine Closure Times [Texte imprimé et/ou numérique] / N. COBAN, Auteur ; C. GOKCEN, Auteur ; S. AKBAYRAM, Auteur ; B. CALISGAN, Auteur . - 2019 . - p.1069-1076. Langues : Anglais (eng) in Autism Research > 12-7 (July 2019) . - p.1069-1076 Mots-clés : autism spectrum disorder  blood platelets  child psychiatry  platelet function tests  serotonin Index. décimale : PER Périodiques Résumé : Changes related to the serotonin system play a key role in the etiology of autism spectrum disorder (ASD). Although we know that platelets are associated with the serotonin system, their relation to ASD has not yet been elucidated. In this study, we aim to investigate platelet parameters in children with ASD. Forty patients with ASD according to Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) and 30 healthy controls were included in the study. A complete blood count was done to measure parameters relating to platelet morphology. Moreover, prothrombin time (PT) and activated partial thromboplastin time (aPTT) were evaluated. Lastly, platelet functions were assessed with a platelet functions analyzer 100 (PFA-100) device by measuring collagen-ADP and collagen-epinephrine (EPI) closure times. There was not a significant difference between the groups in terms of platelet count, mean platelet volume (MPV), platelet distribution width, plateletcrit, PT, or aPTT parameters for ASD patients when compared to the control group (P > 0.05). However, MPV in severe ASD, as quantified by the Childhood Autism Rating Scale, was found to be significantly lower when compared to mild to moderate ASD (P = 0.047). Moreover, in terms of platelet functions, the elongation in collagen-ADP and collagen-EPI closure times were significantly higher for the ASD group (P = 0.044). These results may suggest an impairment in platelet functions rather than in platelet morphology for children with ASD. Considering these results, further investigation of thrombocyte functions in the ASD may lead to a better understanding of the pathogenesis of ASD and to the development of our limited knowledge of this disorder. Autism Res 2019, 12: 1069-1076. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Serotonin is a chemical that is found in brain as wells as in blood cells that function in blood clotting in the human body. There are problems related to serotonin in brains of people who have autism. Thus, blood clotting cells may also be affected in people who have autism. In this study, we compare blood clotting functions of children with autism with that of healthy controls. En ligne : http://dx.doi.org/10.1002/aur.2122 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi-Center, Cross-Sectional, Case-Control Study / MÖ KÜTÜK in Journal of Autism and Developmental Disorders, 51-11 (November 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4086-4099 Titre : High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi-Center, Cross-Sectional, Case-Control Study Type de document : Texte imprimé et/ou numérique Auteurs : MÖ KÜTÜK, Auteur ; A. E. TUFAN, Auteur ; F. KILIÇASLAN, Auteur ; G. GÜLER, Auteur ; F. ÇELIK, Auteur ; E. ALTINTA?, Auteur ; C. GOKCEN, Auteur ; M. KARADA?, Auteur ; Ç YEKTA?, Auteur ; T. MUTLUER, Auteur ; H. KANDEMIR, Auteur ; A. BÜBER, Auteur ; Z. TOPAL, Auteur ; U. ACIKBAS, Auteur ; A. GIRAY, Auteur ; Ö KÜTÜK, Auteur Article en page(s) : p.4086-4099 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/epidemiology  Burnout, Psychological/epidemiology  Case-Control Studies  Child  Cross-Sectional Studies  Depression/epidemiology  Female  Humans  Male  Mothers  Parents  Stress, Psychological  Asd  Burnout  Depression  Parent Index. décimale : PER Périodiques Résumé : The diagnosis of autism spectrum disorder (ASD) in a child affects family processes, increases parenting stress and marital conflicts, and may lead to parental psychopathology. It may also affect the prognosis for their children. The aim of this study is to determine depression and burnout levels as well as their predictors among parents of children with ASD compared with those of healthy children. We also sought to evaluate rate of complementary and alternative medicine (CAM) interventions among parents and explore the associations of this phenomenon in an exploratory fashion. 145 children with ASD and 127 control children were enrolled along with their mothers and fathers. Beck Depression Inventory and Maslach Burnout Inventory were used to evaluate parents' depression symptoms and burnout levels. Symptoms of children with ASDs were evaluated according to the Childhood Autism Rating Scale by the clinicians. Family, child and CAM variables were screened by means of a sociodemographic data form. Descriptive, bivariate and correlation analyses were used in statistical evaluations. Predictors of burnout were evaluated with multiple regression analysis. Burnout and depression levels among parents of children with ASD were significantly elevated compared to controls. Burnout levels of mothers were significantly elevated compared to fathers while depression scores of fathers were significantly elevated compared to mothers. Maternal burnout was significantly predicted by presence of functional speech in child while paternal burnout was significantly predicted by paternal vocation. Maternal depression was associated with paternal depression, lack of speech in child and attendance of child to special education services. Paternal depression was associated with autistic symptom severity and maternal depression. More than half the parents sought CAM interventions. Education level did not affect search for CAM interventions while both maternal and paternal psychopathology and presence of epilepsy among children increased use of CAM methods. Psychological support should be provided to both mothers and fathers of a child receiving a diagnosis of ASD. Addressing parents' burnout and stress levels and facilitating their negotiation of knowledge on etiology and treatments for ASD may be beneficial for the family unit as a whole. En ligne : http://dx.doi.org/10.1007/s10803-021-04874-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] High Depression Symptoms and Burnout Levels Among Parents of Children with Autism Spectrum Disorders: A Multi-Center, Cross-Sectional, Case-Control Study [Texte imprimé et/ou numérique] / MÖ KÜTÜK, Auteur ; A. E. TUFAN, Auteur ; F. KILIÇASLAN, Auteur ; G. GÜLER, Auteur ; F. ÇELIK, Auteur ; E. ALTINTA?, Auteur ; C. GOKCEN, Auteur ; M. KARADA?, Auteur ; Ç YEKTA?, Auteur ; T. MUTLUER, Auteur ; H. KANDEMIR, Auteur ; A. BÜBER, Auteur ; Z. TOPAL, Auteur ; U. ACIKBAS, Auteur ; A. GIRAY, Auteur ; Ö KÜTÜK, Auteur . - p.4086-4099. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4086-4099 Mots-clés : Autism Spectrum Disorder/epidemiology  Burnout, Psychological/epidemiology  Case-Control Studies  Child  Cross-Sectional Studies  Depression/epidemiology  Female  Humans  Male  Mothers  Parents  Stress, Psychological  Asd  Burnout  Depression  Parent Index. décimale : PER Périodiques Résumé : The diagnosis of autism spectrum disorder (ASD) in a child affects family processes, increases parenting stress and marital conflicts, and may lead to parental psychopathology. It may also affect the prognosis for their children. The aim of this study is to determine depression and burnout levels as well as their predictors among parents of children with ASD compared with those of healthy children. We also sought to evaluate rate of complementary and alternative medicine (CAM) interventions among parents and explore the associations of this phenomenon in an exploratory fashion. 145 children with ASD and 127 control children were enrolled along with their mothers and fathers. Beck Depression Inventory and Maslach Burnout Inventory were used to evaluate parents' depression symptoms and burnout levels. Symptoms of children with ASDs were evaluated according to the Childhood Autism Rating Scale by the clinicians. Family, child and CAM variables were screened by means of a sociodemographic data form. Descriptive, bivariate and correlation analyses were used in statistical evaluations. Predictors of burnout were evaluated with multiple regression analysis. Burnout and depression levels among parents of children with ASD were significantly elevated compared to controls. Burnout levels of mothers were significantly elevated compared to fathers while depression scores of fathers were significantly elevated compared to mothers. Maternal burnout was significantly predicted by presence of functional speech in child while paternal burnout was significantly predicted by paternal vocation. Maternal depression was associated with paternal depression, lack of speech in child and attendance of child to special education services. Paternal depression was associated with autistic symptom severity and maternal depression. More than half the parents sought CAM interventions. Education level did not affect search for CAM interventions while both maternal and paternal psychopathology and presence of epilepsy among children increased use of CAM methods. Psychological support should be provided to both mothers and fathers of a child receiving a diagnosis of ASD. Addressing parents' burnout and stress levels and facilitating their negotiation of knowledge on etiology and treatments for ASD may be beneficial for the family unit as a whole. En ligne : http://dx.doi.org/10.1007/s10803-021-04874-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

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