Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study / Rebecca E. LACEY ; Louise ARSENEAULT ; Avshalom CASPI ; Eloise CRUSH ; Andrea DANESE ; Rachel M. LATHAM ; Terrie E. MOFFITT ; Joanne B. NEWBURY ; Jonathan D. SCHAEFER ; Helen L. FISHER ; Jessie R. BALDWIN in Journal of Child Psychology and Psychiatry, 66-5 (May 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.650-658 Titre : Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca E. LACEY, Auteur ; Louise ARSENEAULT, Auteur ; Avshalom CASPI, Auteur ; Eloise CRUSH, Auteur ; Andrea DANESE, Auteur ; Rachel M. LATHAM, Auteur ; Terrie E. MOFFITT, Auteur ; Joanne B. NEWBURY, Auteur ; Jonathan D. SCHAEFER, Auteur ; Helen L. FISHER, Auteur ; Jessie R. BALDWIN, Auteur Article en page(s) : p.650-658 Langues : Anglais (eng) Mots-clés : Protective factors  ACEs  twin differences  adult social support  maternal warmth  psychopathology  resilience Index. décimale : PER Périodiques Résumé : Background Adverse childhood experiences (ACEs) are associated with mental health problems, but many children who experience ACEs do not develop such difficulties. A warm and supportive adult presence in childhood is associated with a lower likelihood of developing mental health problems after exposure to ACEs. However, it is unclear whether this association is causal, as previous research has not accounted for genetic and environmental confounding. Methods We used the twin-difference design to strengthen causal inference about whether a warm and supportive adult presence protects children exposed to ACEs from mental health problems. Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a UK population-representative birth cohort of 2,232 same-sex twins. ACEs were measured prospectively from ages 5 to 12. Maternal warmth was assessed at ages 5 and 10 through maternal speech samples. Adult support was assessed through child reports at age 12. Mental health problems were assessed through interviews at age 12 with parents and teachers and participants at age 18. Results Among children exposed to ACEs, those who experienced greater maternal warmth and adult support had lower levels of mental health problems at ages 12 and 18. In monozygotic twin-difference analyses, the protective effects of maternal warmth and adult support on mental health were attenuated by 70% for maternal warmth and 81% for adult support, compared to phenotypic analyses. Twins who experienced greater maternal warmth and adult support had minimal or no difference in mental health compared to their co-twins, concordant for ACE exposure. Conclusions The apparent protective effect of a warm, supportive adult against mental health problems following ACEs is largely explained by genetic and environmental confounding. This suggests that interventions which boost maternal warmth and adult support should be supplemented by components addressing wider family environments and heritable vulnerabilities in children exposed to adversity, to improve mental health. En ligne : https://doi.org/10.1111/jcpp.14070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554 [article] Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study [Texte imprimé et/ou numérique] / Rebecca E. LACEY, Auteur ; Louise ARSENEAULT, Auteur ; Avshalom CASPI, Auteur ; Eloise CRUSH, Auteur ; Andrea DANESE, Auteur ; Rachel M. LATHAM, Auteur ; Terrie E. MOFFITT, Auteur ; Joanne B. NEWBURY, Auteur ; Jonathan D. SCHAEFER, Auteur ; Helen L. FISHER, Auteur ; Jessie R. BALDWIN, Auteur . - p.650-658. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.650-658 Mots-clés : Protective factors  ACEs  twin differences  adult social support  maternal warmth  psychopathology  resilience Index. décimale : PER Périodiques Résumé : Background Adverse childhood experiences (ACEs) are associated with mental health problems, but many children who experience ACEs do not develop such difficulties. A warm and supportive adult presence in childhood is associated with a lower likelihood of developing mental health problems after exposure to ACEs. However, it is unclear whether this association is causal, as previous research has not accounted for genetic and environmental confounding. Methods We used the twin-difference design to strengthen causal inference about whether a warm and supportive adult presence protects children exposed to ACEs from mental health problems. Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a UK population-representative birth cohort of 2,232 same-sex twins. ACEs were measured prospectively from ages 5 to 12. Maternal warmth was assessed at ages 5 and 10 through maternal speech samples. Adult support was assessed through child reports at age 12. Mental health problems were assessed through interviews at age 12 with parents and teachers and participants at age 18. Results Among children exposed to ACEs, those who experienced greater maternal warmth and adult support had lower levels of mental health problems at ages 12 and 18. In monozygotic twin-difference analyses, the protective effects of maternal warmth and adult support on mental health were attenuated by 70% for maternal warmth and 81% for adult support, compared to phenotypic analyses. Twins who experienced greater maternal warmth and adult support had minimal or no difference in mental health compared to their co-twins, concordant for ACE exposure. Conclusions The apparent protective effect of a warm, supportive adult against mental health problems following ACEs is largely explained by genetic and environmental confounding. This suggests that interventions which boost maternal warmth and adult support should be supplemented by components addressing wider family environments and heritable vulnerabilities in children exposed to adversity, to improve mental health. En ligne : https://doi.org/10.1111/jcpp.14070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554

Difficulties with emotion regulation as a transdiagnostic mechanism linking child maltreatment with the emergence of psychopathology / David G. WEISSMAN in Development and Psychopathology, 31-3 (August 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-3 (August 2019) . - p.899-915 Titre : Difficulties with emotion regulation as a transdiagnostic mechanism linking child maltreatment with the emergence of psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : David G. WEISSMAN, Auteur ; Debbie BITRAN, Auteur ; Adam Bryant MILLER, Auteur ; Jonathan D. SCHAEFER, Auteur ; Margaret A. SHERIDAN, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.899-915 Langues : Anglais (eng) Mots-clés : adversity  attention bias  p factor  rumination  threat Index. décimale : PER Périodiques Résumé : Childhood maltreatment is associated with increased risk for most forms of psychopathology. We examine emotion dysregulation as a transdiagnostic mechanism linking maltreatment with general psychopathology. A sample of 262 children and adolescents participated; 162 (61.8%) experienced abuse or exposure to domestic violence. We assessed four emotion regulation processes (cognitive reappraisal, attention bias to threat, expressive suppression, and rumination) and emotional reactivity. Psychopathology symptoms were assessed concurrently and at a 2-year longitudinal follow-up. A general psychopathology factor (p factor), representing co-occurrence of psychopathology symptoms across multiple internalizing and externalizing domains, was estimated using confirmatory factor analysis. Maltreatment was associated with heightened emotional reactivity and greater use of expressive suppression and rumination. The association of maltreatment with attention bias varied across development, with maltreated children exhibiting a bias toward threat and adolescents a bias away from threat. Greater emotional reactivity and engagement in rumination mediated the longitudinal association between maltreatment and increased general psychopathology over time. Emotion dysregulation following childhood maltreatment occurs at multiple stages of the emotion generation process, in some cases varies across development, and serves as a transdiagnostic mechanism linking child maltreatment with general psychopathology. En ligne : http://dx.doi.org/10.1017/S0954579419000348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Difficulties with emotion regulation as a transdiagnostic mechanism linking child maltreatment with the emergence of psychopathology [Texte imprimé et/ou numérique] / David G. WEISSMAN, Auteur ; Debbie BITRAN, Auteur ; Adam Bryant MILLER, Auteur ; Jonathan D. SCHAEFER, Auteur ; Margaret A. SHERIDAN, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.899-915. Langues : Anglais (eng) in Development and Psychopathology > 31-3 (August 2019) . - p.899-915 Mots-clés : adversity  attention bias  p factor  rumination  threat Index. décimale : PER Périodiques Résumé : Childhood maltreatment is associated with increased risk for most forms of psychopathology. We examine emotion dysregulation as a transdiagnostic mechanism linking maltreatment with general psychopathology. A sample of 262 children and adolescents participated; 162 (61.8%) experienced abuse or exposure to domestic violence. We assessed four emotion regulation processes (cognitive reappraisal, attention bias to threat, expressive suppression, and rumination) and emotional reactivity. Psychopathology symptoms were assessed concurrently and at a 2-year longitudinal follow-up. A general psychopathology factor (p factor), representing co-occurrence of psychopathology symptoms across multiple internalizing and externalizing domains, was estimated using confirmatory factor analysis. Maltreatment was associated with heightened emotional reactivity and greater use of expressive suppression and rumination. The association of maltreatment with attention bias varied across development, with maltreated children exhibiting a bias toward threat and adolescents a bias away from threat. Greater emotional reactivity and engagement in rumination mediated the longitudinal association between maltreatment and increased general psychopathology over time. Emotion dysregulation following childhood maltreatment occurs at multiple stages of the emotion generation process, in some cases varies across development, and serves as a transdiagnostic mechanism linking child maltreatment with general psychopathology. En ligne : http://dx.doi.org/10.1017/S0954579419000348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design / Emily R. PADRUTT in Journal of Child Psychology and Psychiatry, 64-8 (August 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-8 (August 2023) . - p.1232-1241 Titre : Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design Type de document : Texte imprimé et/ou numérique Auteurs : Emily R. PADRUTT, Auteur ; Jeremy HARPER, Auteur ; Jonathan D. SCHAEFER, Auteur ; Kayla M. NELSON, Auteur ; Matt MCGUE, Auteur ; William G. IACONO, Auteur ; Sylia WILSON, Auteur Article en page(s) : p.1232-1241 Langues : Anglais (eng) Mots-clés : Pubertal timing  substance use  risky behavior  peer problems  psychopathology Index. décimale : PER Périodiques Résumé : Background Psychopathology and risky behaviors increase during adolescence, and understanding which adolescents are most at risk informs prevention and intervention efforts. Pubertal timing relative to same-sex, same-age peers is a known correlate of adolescent outcomes among both boys and girls. However, it remains unclear whether this relation is better explained by a plausible causal process or unobserved familial liability. Methods We extended previous research by examining associations between pubertal timing in early adolescence (age 14) and outcomes in later adolescence (age 17) in a community sample of 2,510 twins (49% boys, 51% girls). Results Earlier pubertal timing was associated with more substance use, risk behavior, internalizing and externalizing problems, and peer problems in later adolescence; these effects were small, consistent with previous literature. Follow-up co-twin control analyses indicated that within-twin-pair differences in pubertal timing were not associated with within-twin-pair differences in most adolescent outcomes after accounting for shared familial liability, suggesting that earlier pubertal timing and adolescent outcomes both reflect familial risk factors. Biometric models indicated that associations between earlier pubertal timing and negative adolescent outcomes were largely attributable to shared genetic liability. Conclusions Although earlier pubertal timing was associated with negative adolescent outcomes, our results suggests that these associations did not appear to be caused by earlier pubertal timing but were likely caused by shared genetic influences. En ligne : https://doi.org/10.1111/jcpp.13808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508 [article] Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design [Texte imprimé et/ou numérique] / Emily R. PADRUTT, Auteur ; Jeremy HARPER, Auteur ; Jonathan D. SCHAEFER, Auteur ; Kayla M. NELSON, Auteur ; Matt MCGUE, Auteur ; William G. IACONO, Auteur ; Sylia WILSON, Auteur . - p.1232-1241. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-8 (August 2023) . - p.1232-1241 Mots-clés : Pubertal timing  substance use  risky behavior  peer problems  psychopathology Index. décimale : PER Périodiques Résumé : Background Psychopathology and risky behaviors increase during adolescence, and understanding which adolescents are most at risk informs prevention and intervention efforts. Pubertal timing relative to same-sex, same-age peers is a known correlate of adolescent outcomes among both boys and girls. However, it remains unclear whether this relation is better explained by a plausible causal process or unobserved familial liability. Methods We extended previous research by examining associations between pubertal timing in early adolescence (age 14) and outcomes in later adolescence (age 17) in a community sample of 2,510 twins (49% boys, 51% girls). Results Earlier pubertal timing was associated with more substance use, risk behavior, internalizing and externalizing problems, and peer problems in later adolescence; these effects were small, consistent with previous literature. Follow-up co-twin control analyses indicated that within-twin-pair differences in pubertal timing were not associated with within-twin-pair differences in most adolescent outcomes after accounting for shared familial liability, suggesting that earlier pubertal timing and adolescent outcomes both reflect familial risk factors. Biometric models indicated that associations between earlier pubertal timing and negative adolescent outcomes were largely attributable to shared genetic liability. Conclusions Although earlier pubertal timing was associated with negative adolescent outcomes, our results suggests that these associations did not appear to be caused by earlier pubertal timing but were likely caused by shared genetic influences. En ligne : https://doi.org/10.1111/jcpp.13808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508

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