Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies / Andrea DANESE in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.236-250 Titre : Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies Type de document : Texte imprimé et/ou numérique Auteurs : Andrea DANESE, Auteur Article en page(s) : p.236-250 Langues : Anglais (eng) Mots-clés : Childhood trauma  adverse childhood experiences  childhood abuse  childhood maltreatment  childhood victimization Index. décimale : PER Périodiques Résumé : Childhood trauma is a key modifiable risk factor for psychopathology. Despite significant scientific advances, traumatised children still have poorer long-term outcomes than nontraumatised children. New research paradigms are, thus, needed. To this end, the review examines three dominant assumptions about measurement, design and analytical strategies. Current research warns against using prospective and retrospective measures of childhood trauma interchangeably; against interpreting cross-sectional differences in putative mediating mechanisms between adults with or without a history of childhood trauma as evidence of longitudinal changes from pre-trauma conditions; and against directly applying explanatory models of resilience or vulnerability to psychopathology in traumatised children to forecast individual risk in unseen cases. The warnings equally apply to research on broader measures of adverse childhood experiences (ACEs). Further research examining these assumptions can generate new insights on how to prevent childhood trauma and its detrimental effects. En ligne : http://dx.doi.org/10.1111/jcpp.13160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 [article] Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies [Texte imprimé et/ou numérique] / Andrea DANESE, Auteur . - p.236-250. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.236-250 Mots-clés : Childhood trauma  adverse childhood experiences  childhood abuse  childhood maltreatment  childhood victimization Index. décimale : PER Périodiques Résumé : Childhood trauma is a key modifiable risk factor for psychopathology. Despite significant scientific advances, traumatised children still have poorer long-term outcomes than nontraumatised children. New research paradigms are, thus, needed. To this end, the review examines three dominant assumptions about measurement, design and analytical strategies. Current research warns against using prospective and retrospective measures of childhood trauma interchangeably; against interpreting cross-sectional differences in putative mediating mechanisms between adults with or without a history of childhood trauma as evidence of longitudinal changes from pre-trauma conditions; and against directly applying explanatory models of resilience or vulnerability to psychopathology in traumatised children to forecast individual risk in unseen cases. The warnings equally apply to research on broader measures of adverse childhood experiences (ACEs). Further research examining these assumptions can generate new insights on how to prevent childhood trauma and its detrimental effects. En ligne : http://dx.doi.org/10.1111/jcpp.13160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420

Associations between ADHD and emotional problems from childhood to young adulthood: a longitudinal genetically sensitive study / Adi STERN in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1234-1242 Titre : Associations between ADHD and emotional problems from childhood to young adulthood: a longitudinal genetically sensitive study Type de document : Texte imprimé et/ou numérique Auteurs : Adi STERN, Auteur ; Jessica AGNEW-BLAIS, Auteur ; Andrea DANESE, Auteur ; Helen L. FISHER, Auteur ; Timothy MATTHEWS, Auteur ; Guilherme V. POLANCZYK, Auteur ; Jasmin WERTZ, Auteur ; Louise ARSENEAULT, Auteur Article en page(s) : p.1234-1242 Langues : Anglais (eng) Mots-clés : Attention deficit/hyperactivity disorder  anxiety  depression  development  genetics Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention deficit/hyperactivity disorder (ADHD) is associated with emotional problems, and their co-occurrence often leads to worse outcomes. We investigated the developmental associations between ADHD and emotional problems from childhood to early adolescence and examined the genetic and environmental contributions to their developmental link. We further tested whether this developmental association remained across the transition to young adulthood. METHODS: We used data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a cohort of 2,232 British twins. In childhood, ADHD and emotional problems were assessed at ages 5, 7, 10 and 12 with mothers' and teachers' reports. At age 18, we used self-reported symptoms according to DSM-5 criteria for ADHD, and DSM-IV for anxiety and depression. RESULTS: Longitudinal analyses showed that earlier ADHD was associated with later emotional problems consistently across childhood. However, earlier emotional problems were not associated with later ADHD symptoms. The developmental association between ADHD and later emotional problems in childhood was entirely explained by common genetic factors. Consistent with results in childhood, earlier symptoms of ADHD were associated with later emotional problems during the transition to young adulthood. CONCLUSIONS: Our findings demonstrate that ADHD symptoms are predictors of the development of emotional problems, from childhood up to young adulthood, through shared genetic influences. Interventions targeting ADHD symptoms might prevent the development of emotional problems. Clinicians treating youth with ADHD must be aware of their risk for developing emotional problems and ought to assess, monitor and treat emotional problems alongside ADHD symptoms from childhood to adulthood. En ligne : http://dx.doi.org/10.1111/jcpp.13217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 [article] Associations between ADHD and emotional problems from childhood to young adulthood: a longitudinal genetically sensitive study [Texte imprimé et/ou numérique] / Adi STERN, Auteur ; Jessica AGNEW-BLAIS, Auteur ; Andrea DANESE, Auteur ; Helen L. FISHER, Auteur ; Timothy MATTHEWS, Auteur ; Guilherme V. POLANCZYK, Auteur ; Jasmin WERTZ, Auteur ; Louise ARSENEAULT, Auteur . - p.1234-1242. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1234-1242 Mots-clés : Attention deficit/hyperactivity disorder  anxiety  depression  development  genetics Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention deficit/hyperactivity disorder (ADHD) is associated with emotional problems, and their co-occurrence often leads to worse outcomes. We investigated the developmental associations between ADHD and emotional problems from childhood to early adolescence and examined the genetic and environmental contributions to their developmental link. We further tested whether this developmental association remained across the transition to young adulthood. METHODS: We used data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a cohort of 2,232 British twins. In childhood, ADHD and emotional problems were assessed at ages 5, 7, 10 and 12 with mothers' and teachers' reports. At age 18, we used self-reported symptoms according to DSM-5 criteria for ADHD, and DSM-IV for anxiety and depression. RESULTS: Longitudinal analyses showed that earlier ADHD was associated with later emotional problems consistently across childhood. However, earlier emotional problems were not associated with later ADHD symptoms. The developmental association between ADHD and later emotional problems in childhood was entirely explained by common genetic factors. Consistent with results in childhood, earlier symptoms of ADHD were associated with later emotional problems during the transition to young adulthood. CONCLUSIONS: Our findings demonstrate that ADHD symptoms are predictors of the development of emotional problems, from childhood up to young adulthood, through shared genetic influences. Interventions targeting ADHD symptoms might prevent the development of emotional problems. Clinicians treating youth with ADHD must be aware of their risk for developing emotional problems and ought to assess, monitor and treat emotional problems alongside ADHD symptoms from childhood to adulthood. En ligne : http://dx.doi.org/10.1111/jcpp.13217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434

Challenges in researching the immune pathways between early life adversity and psychopathology / Brie REID in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1597-1624 Titre : Challenges in researching the immune pathways between early life adversity and psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Brie REID, Auteur ; Andrea DANESE, Auteur Article en page(s) : p.1597-1624 Langues : Anglais (eng) Mots-clés : Biomarkers  Child  Humans  Inflammation  *Psychopathology  Risk Factors  *Stress, Psychological  *childhood adversity  *immunity  *inflammation  *maltreatment  *psychiatric disorders Index. décimale : PER Périodiques Résumé : Exposure to childhood adversity is a critical risk factor for the development of psychopathology. A growing field of research examines how exposure to childhood adversity is translated into biological risk for psychopathology through alterations in immune system functioning, most notably heightened levels of inflammation biomarkers. Though our knowledge about how childhood adversity can instantiate biological risk for psychopathology is growing, there remain many challenges and gaps in the field to understand how inflammation from childhood adversity contributes to psychopathology. This paper reviews research on the inflammatory outcomes arising from childhood adversity and presents four major challenges that future research must address: (a) the measurement of childhood adversity, (b) the measurement of inflammation, (c) the identification of mediators between childhood adversity and inflammation, and (d) the identification of moderators of inflammatory outcomes following childhood adversity. We discuss synergies and inconsistencies in the literature to summarize the current understanding of the association between childhood adversity, a proinflammatory phenotype, and the biological risk for psychopathology. We discuss the clinical implications of the inflammatory links between childhood adversity and psychopathology, including possibilities for intervention. Finally, this review conclude by delineates future directions for research, including issues of how best to detect, prevent, and understand these "hidden wounds" of childhood adversity. En ligne : http://dx.doi.org/10.1017/s0954579420001157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] Challenges in researching the immune pathways between early life adversity and psychopathology [Texte imprimé et/ou numérique] / Brie REID, Auteur ; Andrea DANESE, Auteur . - p.1597-1624. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1597-1624 Mots-clés : Biomarkers  Child  Humans  Inflammation  *Psychopathology  Risk Factors  *Stress, Psychological  *childhood adversity  *immunity  *inflammation  *maltreatment  *psychiatric disorders Index. décimale : PER Périodiques Résumé : Exposure to childhood adversity is a critical risk factor for the development of psychopathology. A growing field of research examines how exposure to childhood adversity is translated into biological risk for psychopathology through alterations in immune system functioning, most notably heightened levels of inflammation biomarkers. Though our knowledge about how childhood adversity can instantiate biological risk for psychopathology is growing, there remain many challenges and gaps in the field to understand how inflammation from childhood adversity contributes to psychopathology. This paper reviews research on the inflammatory outcomes arising from childhood adversity and presents four major challenges that future research must address: (a) the measurement of childhood adversity, (b) the measurement of inflammation, (c) the identification of mediators between childhood adversity and inflammation, and (d) the identification of moderators of inflammatory outcomes following childhood adversity. We discuss synergies and inconsistencies in the literature to summarize the current understanding of the association between childhood adversity, a proinflammatory phenotype, and the biological risk for psychopathology. We discuss the clinical implications of the inflammatory links between childhood adversity and psychopathology, including possibilities for intervention. Finally, this review conclude by delineates future directions for research, including issues of how best to detect, prevent, and understand these "hidden wounds" of childhood adversity. En ligne : http://dx.doi.org/10.1017/s0954579420001157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437

Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort / Sidra GOLDMAN-MELLOR in Journal of Child Psychology and Psychiatry, 57-2 (February 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.196-203 Titre : Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort Type de document : Texte imprimé et/ou numérique Auteurs : Sidra GOLDMAN-MELLOR, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Nifemi AJALA, Auteur ; Antony AMBLER, Auteur ; Andrea DANESE, Auteur ; Helen FISHER, Auteur ; Abigail HUCKER, Auteur ; Candice ODGERS, Auteur ; Teresa WILLIAMS, Auteur ; Chloe WONG, Auteur ; Terrie E. MOFFITT, Auteur Article en page(s) : p.196-203 Langues : Anglais (eng) Mots-clés : Adolescence  depression  self-perceptions  employment  longitudinal studies  mental health Index. décimale : PER Périodiques Résumé : Background Labour market disengagement among youths has lasting negative economic and social consequences, yet is poorly understood. We compared four types of work-related self-perceptions, as well as vulnerability to mental health and substance abuse problems, among youths not in education, employment or training (NEET) and among their peers. Methods Participants were from the Environmental Risk (E-Risk) longitudinal study, a nationally representative UK cohort of 2,232 twins born in 1994–1995. We measured commitment to work, job-search effort, professional/technical skills, ‘soft’ skills (e.g. teamwork, decision-making, communication), optimism about getting ahead, and mental health and substance use disorders at age 18. We also examined childhood mental health. Results At age 18, 11.6% of participants were NEET. NEET participants reported themselves as committed to work and searching for jobs with greater diligence than their non-NEET peers. However, they reported fewer ‘soft’ skills (B = ?0.98, p < .001) and felt less optimistic about their likelihood of getting ahead in life (B = ?2.41, p < .001). NEET youths also had higher rates of concurrent mental health and substance abuse problems, but these did not explain the relationship with work-related self-perceptions. Nearly 60% of NEET (vs. 35% of non-NEET) youths had already experienced ?1 mental health problem in childhood/adolescence. Associations of NEET status with concurrent mental health problems were independent of pre-existing mental health vulnerability. Conclusions Our findings indicate that while NEET is clearly an economic and mental health issue, it does not appear to be a motivation issue. Alongside skills, work-related self-perceptions and mental health problems may be targets for intervention and service provision among this high-risk population. En ligne : http://dx.doi.org/10.1111/jcpp.12459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280 [article] Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort [Texte imprimé et/ou numérique] / Sidra GOLDMAN-MELLOR, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Nifemi AJALA, Auteur ; Antony AMBLER, Auteur ; Andrea DANESE, Auteur ; Helen FISHER, Auteur ; Abigail HUCKER, Auteur ; Candice ODGERS, Auteur ; Teresa WILLIAMS, Auteur ; Chloe WONG, Auteur ; Terrie E. MOFFITT, Auteur . - p.196-203. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.196-203 Mots-clés : Adolescence  depression  self-perceptions  employment  longitudinal studies  mental health Index. décimale : PER Périodiques Résumé : Background Labour market disengagement among youths has lasting negative economic and social consequences, yet is poorly understood. We compared four types of work-related self-perceptions, as well as vulnerability to mental health and substance abuse problems, among youths not in education, employment or training (NEET) and among their peers. Methods Participants were from the Environmental Risk (E-Risk) longitudinal study, a nationally representative UK cohort of 2,232 twins born in 1994–1995. We measured commitment to work, job-search effort, professional/technical skills, ‘soft’ skills (e.g. teamwork, decision-making, communication), optimism about getting ahead, and mental health and substance use disorders at age 18. We also examined childhood mental health. Results At age 18, 11.6% of participants were NEET. NEET participants reported themselves as committed to work and searching for jobs with greater diligence than their non-NEET peers. However, they reported fewer ‘soft’ skills (B = ?0.98, p < .001) and felt less optimistic about their likelihood of getting ahead in life (B = ?2.41, p < .001). NEET youths also had higher rates of concurrent mental health and substance abuse problems, but these did not explain the relationship with work-related self-perceptions. Nearly 60% of NEET (vs. 35% of non-NEET) youths had already experienced ?1 mental health problem in childhood/adolescence. Associations of NEET status with concurrent mental health problems were independent of pre-existing mental health vulnerability. Conclusions Our findings indicate that while NEET is clearly an economic and mental health issue, it does not appear to be a motivation issue. Alongside skills, work-related self-perceptions and mental health problems may be targets for intervention and service provision among this high-risk population. En ligne : http://dx.doi.org/10.1111/jcpp.12459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280

Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences / Jamie MURPHY in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.1034-1044 Titre : Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences Type de document : Texte imprimé et/ou numérique Auteurs : Jamie MURPHY, Auteur ; Mark SHEVLIN, Auteur ; Louise ARSENEAULT, Auteur ; Richard BENTALL, Auteur ; Avshalom CASPI, Auteur ; Andrea DANESE, Auteur ; Philip HYLAND, Auteur ; Terrie E. MOFFITT, Auteur ; Helen L. FISHER, Auteur Article en page(s) : p.1034-1044 Langues : Anglais (eng) Mots-clés : birth-cohort  cross-lagged panel analysis  psychosis  self-harm  self-injurious behavior Index. décimale : PER Périodiques Résumé : A recent suicidal drive hypothesis posits that psychotic experiences (PEs) may serve to externalize internally generated and self-directed threat (i.e., self-injurious/suicidal behavior [SIB]) in order to optimize survival; however, it must first be demonstrated that such internal threat can both precede and inform PEs. The current study conducted the first known bidirectional analysis of SIB and PEs to test whether SIB could be considered as a plausible antecedent for PEs. Prospective data were utilized from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of 2232 twins, that captured SIB (any self-harm or suicidal attempt) and PEs at ages 12 and 18 years. Cross-lagged panel models demonstrated that the association between SIB at age 12 and PEs at age 18 was as strong as the association between PEs at age 12 and SIB at age 18. Indeed, the best representation of the data was a model where these paths were constrained to be equal (OR = 2.48, 95% CI = 1.63 “3.79). Clinical interview case notes for those who reported both SIB and PEs at age 18, revealed that PEs were explicitly characterized by SIB/threat/death-related content for 39% of cases. These findings justify further investigation of the suicidal drive hypothesis. En ligne : http://dx.doi.org/10.1017/S0954579420001728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences [Texte imprimé et/ou numérique] / Jamie MURPHY, Auteur ; Mark SHEVLIN, Auteur ; Louise ARSENEAULT, Auteur ; Richard BENTALL, Auteur ; Avshalom CASPI, Auteur ; Andrea DANESE, Auteur ; Philip HYLAND, Auteur ; Terrie E. MOFFITT, Auteur ; Helen L. FISHER, Auteur . - p.1034-1044. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.1034-1044 Mots-clés : birth-cohort  cross-lagged panel analysis  psychosis  self-harm  self-injurious behavior Index. décimale : PER Périodiques Résumé : A recent suicidal drive hypothesis posits that psychotic experiences (PEs) may serve to externalize internally generated and self-directed threat (i.e., self-injurious/suicidal behavior [SIB]) in order to optimize survival; however, it must first be demonstrated that such internal threat can both precede and inform PEs. The current study conducted the first known bidirectional analysis of SIB and PEs to test whether SIB could be considered as a plausible antecedent for PEs. Prospective data were utilized from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of 2232 twins, that captured SIB (any self-harm or suicidal attempt) and PEs at ages 12 and 18 years. Cross-lagged panel models demonstrated that the association between SIB at age 12 and PEs at age 18 was as strong as the association between PEs at age 12 and SIB at age 18. Indeed, the best representation of the data was a model where these paths were constrained to be equal (OR = 2.48, 95% CI = 1.63 “3.79). Clinical interview case notes for those who reported both SIB and PEs at age 18, revealed that PEs were explicitly characterized by SIB/threat/death-related content for 39% of cases. These findings justify further investigation of the suicidal drive hypothesis. En ligne : http://dx.doi.org/10.1017/S0954579420001728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

Lest we forget: comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health / Aaron REUBEN in Journal of Child Psychology and Psychiatry, 57-10 (October 2016)  

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A longitudinal twin study of victimization and loneliness from childhood to young adulthood / Timothy MATTHEWS in Development and Psychopathology, 34-1 (February 2022)  

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Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study / Helen L. FISHER in Development and Psychopathology, 27-4 (Part 2) (November 2015)  

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Measuring early life adversity: A dimensional approach / Ilana S. BERMAN in Development and Psychopathology, 34-2 (May 2022)  

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Mother's and children's ADHD genetic risk, household chaos and children's ADHD symptoms: A gene-environment correlation study / Jessica AGNEW-BLAIS in Journal of Child Psychology and Psychiatry, 63-10 (October 2022)  

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A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents / Alicia J. PEEL in Journal of Child Psychology and Psychiatry, 64-2 (February 2023)  

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The developmental course of loneliness in adolescence: Implications for mental health, educational attainment, and psychosocial functioning / Timothy MATTHEWS in Development and Psychopathology, 35-2 (May 2023)  

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