[article]
| Titre : |
Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD) |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur |
| Article en page(s) : |
p.2511-2517 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Adolescent Adult Autism Spectrum Disorder/blood Biomarkers/blood Case-Control Studies Child Child, Preschool Humans Leukocytes, Mononuclear Male Monocytes/immunology Oxidative Stress Peroxidase/blood Serum Albumin Serum Albumin, Human Asd Autism spectrum disorder Ima Ischemia-modified albumin Lymphocytes Monocytes Myeloperoxidase Neutrophils |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Genetic, neurobiological, neurochemical, environmental factors and their interactions contribute to autism phenotypes. Blood from 48 (age range: 4-17) autism spectrum disorder diagnosed patients (ASD) and 38 age- and gender-matched healthy control subjects was analyzed for numbers of neutrophils, lymphocytes, monocytes, albumin, serum Ischemia-Modified Albumin (IMA) levels and myeloperoxidase activity. The serum IMA levels, myeloperoxidase activity and peripheral blood mononuclear cells count were significantly higher in ASD cases than in the control subjects. There were no significant differences in albumin levels between the patient and control groups. These results suggest that the immune system, oxidative stress and myeloperoxidase activity may be activated in ASD. There is a clinical benefit from the early detection of ASD using myeloperoxidase activity, IMA levels and monocyte counts. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-020-04740-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 |
in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2511-2517
[article] Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear cells in Autism Spectrum Disorder (ASD) [Texte imprimé et/ou numérique] / Mehmet Fatih CEYLAN, Auteur ; S. TURAL HESAPCIOGLU, Auteur ; C. P. YAVAS, Auteur ; A. SENAT, Auteur ; O. EREL, Auteur . - p.2511-2517. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2511-2517
| Mots-clés : |
Adolescent Adult Autism Spectrum Disorder/blood Biomarkers/blood Case-Control Studies Child Child, Preschool Humans Leukocytes, Mononuclear Male Monocytes/immunology Oxidative Stress Peroxidase/blood Serum Albumin Serum Albumin, Human Asd Autism spectrum disorder Ima Ischemia-modified albumin Lymphocytes Monocytes Myeloperoxidase Neutrophils |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Genetic, neurobiological, neurochemical, environmental factors and their interactions contribute to autism phenotypes. Blood from 48 (age range: 4-17) autism spectrum disorder diagnosed patients (ASD) and 38 age- and gender-matched healthy control subjects was analyzed for numbers of neutrophils, lymphocytes, monocytes, albumin, serum Ischemia-Modified Albumin (IMA) levels and myeloperoxidase activity. The serum IMA levels, myeloperoxidase activity and peripheral blood mononuclear cells count were significantly higher in ASD cases than in the control subjects. There were no significant differences in albumin levels between the patient and control groups. These results suggest that the immune system, oxidative stress and myeloperoxidase activity may be activated in ASD. There is a clinical benefit from the early detection of ASD using myeloperoxidase activity, IMA levels and monocyte counts. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-020-04740-9 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 |
|
Faire une suggestion Affiner la rechercheCorrection to: Serum Ischemia-Modified Albumin Levels, Myeloperoxidase Activity and Peripheral Blood Mononuclear Cells in Autism Spectrum Disorder (ASD) / Mehmet Fatih CEYLAN in Journal of Autism and Developmental Disorders, 51-7 (July 2021)
